arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2102.02506cond-mat.softcond-mat.mtrl-sciphysics.bio-ph
收藏

弹性介质中空化对液滴尺寸的控制

Cavitation controls droplet sizes in elastic media

Estefania Vidal-Henriquez, David Zwicker

摘要:

生物细胞使用液滴来分离组分并在空间上控制其内部。实验表明,复杂,拥挤的细胞环境影响液滴的排列和它们的大小。为了理解这种行为,我们在这里构建了一个理论描述的液滴在弹性基质中生长,这是由实验在合成系统中的单分散乳液在温度下降过程中形成的动机。我们表明,大液滴只形成时,他们打破周围的矩阵在空化事件。与空化相关联的能量屏障使小液滴在网格尺寸的量级上稳定,并减少成核的随机效应。因此,空化液滴具有相似的尺寸和高度相关的位置。特别是,我们预测空化液滴的密度,随着冷却速度的增加,在实验中。我们的模型还表明如何调整冷却协议和成核点的密度影响液滴尺寸分布。总之,我们的理论解释了弹性基质如何影响合成系统中的液滴,并为理解生物学案例提供了一个框架。

英文摘要:

Biological cells use droplets to separate components and spatially control their interior. Experiments demonstrate that the complex, crowded cellular environment affects the droplet arrangement and their sizes. To understand this behavior, we here construct a theoretical description of droplets growing in an elastic matrix, which is motivated by experiments in synthetic systems where monodisperse emulsions form during a temperature decrease. We show that large droplets only form when they break the surrounding matrix in a cavitation event. The energy barrier associated with cavitation stabilizes small droplets on the order of the mesh size and diminishes the stochastic effects of nucleation. Consequently, the cavitated droplets have similar sizes and highly correlated positions. In particular, we predict the density of cavitated droplets, which increases with faster cooling, as in the experiments. Our model also suggests how adjusting the cooling protocol and the density of nucleation sites affects the droplet size distribution. In summary, our theory explains how elastic matrices affect droplets in the synthetic system and it provides a framework for understanding the biological case.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑