AI 中文总结
研究脂质和液晶中分子组织到介观形状转变，通过偏振光学显微镜研究单油酸甘油酯掺杂8CB液滴温度依赖结构演变，发现内部单油酸甘油酯浓度和外部脂质环境共同调控相变等，揭示相关转变及形态动力学机制，确立脂质相关参数的关键作用。
AI 中文摘要
脂质和液晶为研究分子尺度组织如何转化为介观尺度形状转变提供了有用平台。烃链堆积变化可改变界面秩序、锚定条件和弹性应力，可能将分子组织与液滴形态耦合。本文研究了分散在磷脂水溶液中的单油酸甘油酯掺杂的4-辛基-4'-氰基联苯（8CB）液滴的温度依赖性结构演变。利用偏振光学显微镜表明，内部单油酸甘油酯浓度和外部脂质环境共同调节加热过程中的相变、细丝化和更大变形。液滴经历耦合的近晶-向列-各向同性转变，仅在近晶态观察到细长细丝。在近晶-向列转变时，观察到液滴形状变形的突然和不连续开始，揭示了与体相中间相转变耦合的形状变化转变。这是首次报道与近晶-向列相转变同时发生的不连续液滴形状变化转变。改变内部和外部脂质含量可重定向细丝主导的近晶响应和更多无定形向列形状变化之间的重构途径。界面张力测量进一步表明，液晶-水界面张力的更强降低不一定产生细丝化或变形。相反，观察到的形态动力学源于体相弹性、中间相结构和脂质介导的界面组织之间的耦合。这些发现确立了脂质组成和烃链结构是控制液晶液滴热诱导形状转变的关键参数。
英文摘要
Lipids and liquid crystals provide a useful platform for addressing how molecular-scale organization is translated into mesoscale shape transformation. Variations in hydrocarbon-chain packing can modify interfacial order, anchoring conditions, and elastic stresses, potentially coupling molecular organization to droplet morphology. Here, we investigate the temperature-dependent structural evolution of monoolein-doped 4-octyl-4'-cyanobiphenyl (8CB) droplets dispersed in aqueous phospholipid solutions. Using polarized optical microscopy, we show that the internal monoolein concentration and the external lipid environment jointly regulate phase transitions, thin filamentation, and larger deformations during heating. The droplets undergo coupled smectic-nematic-isotropic transitions, with extended thin filaments observed exclusively in the smectic regime. At the smectic-to-nematic transition, we observe an abrupt and discontinuous onset of droplet shape deformation, revealing a shape-change transition coupled to the bulk mesophase transition. To our knowledge, this is the first report of a discontinuous droplet-shape-change transition coincident with a smectic-to-nematic phase transition. Varying the internal and external lipid contents redirects the reconfiguration pathway between filament-dominated smectic responses and more amorphous nematic shape changes. Interfacial tension measurements further show that stronger reductions in liquid-crystal-aqueous interfacial tension do not necessarily produce filamentation or deformation. Instead, the observed morphodynamics arise from the coupling between bulk elasticity, mesophase structure, and lipid-mediated interfacial organization. These findings establish lipid composition and hydrocarbon-chain architecture as key parameters governing thermally induced shape transformations in liquid crystal droplets.
