Landmark detection in Cardiac Magnetic Resonance Imaging Using A Convolutional Neural Network
National Heart, Lung and Blood Institute, National Institutes of Health（美国国立卫生研究院心肺血液研究所）；Barts Heart Centre, Barts Health NHS Trust（巴特健康国民保健信托巴特心脏中心）；National Amyloidosis Centre, Royal Free Hospital（皇家自由医院国家淀粉样变性病中心）
Hui Xue, Jessica Artico, Marianna Fontana, James C Moon, Rhodri H Davies, Peter Kellman
Purpose: To develop a convolutional neural network (CNN) solution for robust landmark detection in cardiac MR images.
Methods: This retrospective study included cine, LGE and T1 mapping scans from two hospitals. The training set included 2,329 patients and 34,019 images. A hold-out test set included 531 patients and 7,723 images. CNN models were developed to detect two mitral valve plane and apical points on long-axis (LAX) images. On short-axis (SAX) images, anterior and posterior RV insertion points and LV center were detected. Model outputs were compared to manual labels by two operators for accuracy with a t-test for statistical significance. The trained model was deployed to MR scanners.
Results: For the LAX images, success detection was 99.8% for cine, 99.4% for LGE. For the SAX, success rate was 96.6%, 97.6% and 98.9% for cine, LGE and T1-mapping. The L2 distances between model and manual labels were 2 to 3.5 mm, indicating close agreement between model landmarks to manual labels. No significant differences were found for the anterior RV insertion angle and LV length by the models and operators for all views and imaging sequences. Model inference on MR scanner took 610ms/5.6s on GPU/CPU, respectively, for a typical cardiac cine series.
Conclusions: This study developed, validated and deployed a CNN solution for robust landmark detection in both long and short-axis CMR images for cine, LGE and T1 mapping sequences, with the accuracy comparable to the inter-operator variation.
Automatic segmentation of myocardial contours and relevant areas like infraction and no-reflow is an important step for the quantitative evaluation of myocardial infarction. In this work, we propose a cascaded convolutional neural network for automatic myocardial infarction segmentation from delayed-enhancement cardiac MRI. We first use a 2D U-Net to focus on the intra-slice information to perform a preliminary segmentation. After that, we use a 3D U-Net to utilize the volumetric spatial information for a subtle segmentation. Our method is evaluated on the MICCAI 2020 EMIDEC challenge dataset …
Research Institute for Signals, Systems and Computational Intelligence, sinc(i)（信号、系统与计算智能研究所）；CONICET（国家科学技术研究委员会）；Universidad Nacional del Litoral（国立滨海大学）
In this work we address the problem of landmark-based segmentation for anatomical structures. We propose HybridGNet, an encoder-decoder neural architecture which combines standard convolutions for image feature encoding, with graph convolutional neural networks to decode plausible representations of anatomical structures. We benchmark the proposed architecture considering other standard landmark and pixel-based models for anatomical segmentation in chest x-ray images, and found that HybridGNet is more robust to image occlusions. We also show that it can be used to construct landmark-based segm…
United Imaging Intelligence（联影智能）；UIH America, Inc.（联影美国公司）
Real-time cardiac cine MRI does not require ECG gating in the data acquisition and is more useful for patients who can not hold their breaths or have abnormal heart rhythms. However, to achieve fast image acquisition, real-time cine commonly acquires highly undersampled data, which imposes a significant challenge for MRI image reconstruction. We propose a residual convolutional RNN for real-time cardiac cine reconstruction. To the best of our knowledge, this is the first work applying deep learning approach to Cartesian real-time cardiac cine reconstruction. Based on the evaluation from radiol…
Rice University（莱斯大学）；Prudence Medical Technologies Ltd（审慎医疗技术有限公司）
We train an enhanced deep convolutional neural network in order to identify eight cardiac abnormalities from the standard 12-lead electrocardiograms (ECGs) using the dataset of 14000 ECGs. Instead of straightforwardly applying an end-to-end deep learning approach, we find that deep convolutional neural networks enhanced with sophisticated hand crafted features show advantages in reducing generalization errors. Additionally, data preprocessing and augmentation are essential since the distribution of eight cardiac abnormalities are highly biased in the given dataset. Our approach achieves promis…
University of Dundee（邓迪大学）；Technical University of Munich（慕尼黑工业大学）；Shenzhen Institute of Artificial Intelligence and Robotics for Society（深圳人工智能与机器人研究院）；Southern University of Science and Technology（南方科技大学）
Analysis and modeling of the ventricles and myocardium are important in the diagnostic and treatment of heart diseases. Manual delineation of those tissues in cardiac MR (CMR) scans is laborious and time-consuming. The ambiguity of the boundaries makes the segmentation task rather challenging. Furthermore, the annotations on some modalities such as Late Gadolinium Enhancement (LGE) MRI, are often not available. We propose an end-to-end segmentation framework based on convolutional neural network (CNN) and adversarial learning. A dilated residual U-shape network is used as a segmentor to genera…
Graz University of Technology（格拉茨工业大学）；Ludwig Boltzmann Institute for Clinical Forensic Imaging（路德维希·玻尔兹曼临床法医成像研究所）
In many medical image analysis applications, often only a limited amount of training data is available, which makes training of convolutional neural networks (CNNs) challenging. In this work on anatomical landmark localization, we propose a CNN architecture that learns to split the localization task into two simpler sub-problems, reducing the need for large training datasets. Our fully convolutional SpatialConfiguration-Net (SCN) dedicates one component to locally accurate but ambiguous candidate predictions, while the other component improves robustness to ambiguities by incorporating the spa…
Towards Robust Cardiac Segmentation using Graph Convolutional Networks
Norwegian University of Science and Technology（挪威科技大学）；University of Oslo（奥斯陆大学）；GE Research（GE研究中心）；St. Olavs hospital（圣奥拉夫斯医院）；Levanger hospital（莱旺厄尔医院）；SINTEF Health（辛特福健康研究院）
Austin Health（奥斯汀健康）；The University of Melbourne（墨尔本大学）；Kings College London（伦敦国王学院）；I-MED Radiology（I-MED放射科）；University of Porto（波尔图大学）
Objectives: To develop an image-based automatic deep learning method to classify cardiac MR images by sequence type and imaging plane for improved clinical post-processing efficiency. Methods: Multi-vendor cardiac MRI studies were retrospectively collected from 4 centres and 3 vendors. A two-head convolutional neural network ('CardiSort') was trained to classify 35 sequences by imaging sequence (n=17) and plane (n=10). Single vendor training (SVT) on single centre images (n=234 patients) and multi-vendor training (MVT) with multicentre images (n = 479 patients, 3 centres) was performed. Model …
In the field of medical image, deep convolutional neural networks(ConvNets) have achieved great success in the classification, segmentation, and registration tasks thanks to their unparalleled capacity to learn image features. However, these tasks often require large amounts of manually annotated data and are labor-intensive. Therefore, it is of significant importance for us to study unsupervised semantic feature learning tasks. In our work, we propose to learn features in medical images by training ConvNets to recognize the geometric transformation applied to images and present a simple self-…
Cine cardiac MRI reconstruction using a convolutional recurrent network with refinement
Institute for Digital Communications, University of Edinburgh（爱丁堡大学数字通信研究所）；Institute of Information Science and Technologies “Alessandro Faedo”, National Research Council of Italy (CNR)（意大利国家研究委员会信息科学与技术研究所（亚历山德罗·法埃多））；Department of Information Engineering, University of Pisa（比萨大学信息工程系）；Institute for Infrastructure and Environment, University of Edinburgh（爱丁堡大学基础设施与环境研究所）；The Alan Turing Institute（阿兰·图灵研究所）
University of Auckland（奥克兰大学）；Johns Hopkins Medical Center（约翰斯·霍普金斯医疗中心）；University of Wisconsin School of Medicine and Public Health（威斯康星大学医学与公共卫生学院）；Aalborg University（奥尔堡大学）；Auckland Bioengineering Institute（奥克兰生物工程研究所）；Eindhoven University of Technology（埃因霍温理工大学）
The shape and motion of the heart provide essential clues to understanding the mechanisms of cardiovascular disease. With the advent of large-scale cardiac imaging data, statistical atlases become a powerful tool to provide automated and precise quantification of the status of patient-specific heart geometry with respect to reference populations. The Multi-Ethnic Study of Atherosclerosis (MESA), begun in 2000, was the first large cohort study to incorporate cardiovascular MRI in over 5000 participants, and there is now a wealth of follow-up data over 20 years. Building a machine learning based…
Image Sciences Institute（影像科学研究所）；University Medical Center Utrecht（乌得勒支大学医学中心）；Department of Radiology（放射科）
Detection of coronary artery stenosis in coronary CT angiography (CCTA) requires highly personalized surface meshes enclosing the coronary lumen. In this work, we propose to use graph convolutional networks (GCNs) to predict the spatial location of vertices in a tubular surface mesh that segments the coronary artery lumen. Predictions for individual vertex locations are based on local image features as well as on features of neighboring vertices in the mesh graph. The method was trained and evaluated using the publicly available Coronary Artery Stenoses Detection and Quantification Evaluation …
View planning for the acquisition of cardiac magnetic resonance imaging (CMR) requires acquaintance with the cardiac anatomy and remains a challenging task in clinical practice. Existing approaches to its automation relied either on an additional volumetric image not typically acquired in clinic routine, or on laborious manual annotations of cardiac structural landmarks. This work presents a clinic-compatible and annotation-free system for automatic CMR view planning. The system mines the spatial relationship -- more specifically, locates and exploits the intersecting lines -- between the sour…
Rochester Institute of Technology（罗切斯特理工学院）；Dalhousie University（达尔豪斯大学）
Personalization of cardiac models involves the optimization of organ tissue properties that vary spatially over the non-Euclidean geometry model of the heart. To represent the high-dimensional (HD) unknown of tissue properties, most existing works rely on a low-dimensional (LD) partitioning of the geometrical model. While this exploits the geometry of the heart, it is of limited expressiveness to allow partitioning that is small enough for effective optimization. Recently, a variational auto-encoder (VAE) was utilized as a more expressive generative model to embed the HD optimization into the …
ImViA Laboratory, Université de Bourgogne Franche-Comté（ImViA实验室，弗朗什-孔泰大学）
Ear consists of the smallest bones in the human body and does not contain significant amount of distinct landmark points that may be used to register a preoperative CT-scan with the surgical video in an augmented reality framework. Learning based algorithms may be used to help the surgeons to identify landmark points. This paper presents a convolutional neural network approach to landmark detection in preoperative ear CT images and then discusses an augmented reality system that can be used to visualize the cochlear axis on an otologic surgical video.
Friedrich-Alexander University（弗里德里希-亚历山大大学）；Siemens Healthineers（西门子医疗）；Johns Hopkins University School of Medicine（约翰·霍普金斯大学医学院）
Electroanatomic mapping as routinely acquired in ablation therapy of ventricular tachycardia is the gold standard method to identify the arrhythmogenic substrate. To reduce the acquisition time and still provide maps with high spatial resolution, we propose a novel deep learning method based on graph convolutional neural networks to estimate the depolarization time in the myocardium, given sparse catheter data on the left ventricular endocardium, ECG, and magnetic resonance images. The training set consists of data produced by a computational model of cardiac electrophysiology on a large cohor…
Shanghai Jiao Tong University（上海交通大学）；University of Sydney（悉尼大学）；Ruijin Hospital, Shanghai Jiao Tong University School of Medicine（上海交通大学医学院瑞金医院）
Motion estimation is a fundamental step in dynamic medical image processing for the assessment of target organ anatomy and function. However, existing image-based motion estimation methods, which optimize the motion field by evaluating the local image similarity, are prone to produce implausible estimation, especially in the presence of large motion. In this study, we provide a novel motion estimation framework of Dense-Sparse-Dense (DSD), which comprises two stages. In the first stage, we process the raw dense image to extract sparse landmarks to represent the target organ anatomical topology…
Quantification of cardiac structures in non-contrast CT (NCCT) could improve cardiovascular risk stratification. However, setting a manual reference to train a fully convolutional network (FCN) for automatic segmentation of NCCT images is hardly feasible, and an FCN trained on coronary CT angiography (CCTA) images would not generalize to NCCT. Therefore, we propose to train an FCN with virtual non-contrast (VNC) images from a dual-layer detector CT scanner and a reference standard obtained on perfectly aligned CCTA images.
NVIDIA（英伟达）；MGH and BWH Center for Clinical Data Science（麻省总医院与布列根和妇女医院临床数据科学中心）
We propose a 4D convolutional neural network (CNN) for the segmentation of retrospective ECG-gated cardiac CT, a series of single-channel volumetric data over time. While only a small subset of volumes in the temporal sequence is annotated, we define a sparse loss function on available labels to allow the network to leverage unlabeled images during training and generate a fully segmented sequence. We investigate the accuracy of the proposed 4D network to predict temporally consistent segmentations and compare with traditional 3D segmentation approaches. We demonstrate the feasibility of the 4D…
University of Kansas（堪萨斯大学）；Rochester Institute of Technology（罗切斯特理工学院）
Patient-specific left ventricle (LV) myocardial models have the potential to be used in a variety of clinical scenarios for improved diagnosis and treatment plans. Cine cardiac magnetic resonance (MR) imaging provides high resolution images to reconstruct patient-specific geometric models of the LV myocardium. With the advent of deep learning, accurate segmentation of cardiac chambers from cine cardiac MR images and unsupervised learning for image registration for cardiac motion estimation on a large number of image datasets is attainable. Here, we propose a deep leaning-based framework for th…
In this work, we implement a fully convolutional segmenter featuring both a learned group structure and a regularized weight-pruner to reduce the high computational cost in volumetric image segmentation. We validated our framework on the ACDC dataset featuring one healthy and four pathology groups imaged throughout the cardiac cycle. Our technique achieved Dice scores of 96.8% (LV blood-pool), 93.3% (RV blood-pool) and 90.0% (LV Myocardium) with five-fold cross-validation and yielded similar clinical parameters as those estimated from the ground truth segmentation data. Based on these results,…
We present a method for highly efficient landmark detection that combines deep convolutional neural networks with well established model-based fitting algorithms. Motivated by established model-based fitting methods such as active shapes, we use a PCA of the landmark positions to allow generative modeling of facial landmarks. Instead of computing the model parameters using iterative optimization, the PCA is included in a deep neural network using a novel layer type. The network predicts model parameters in a single forward pass, thereby allowing facial landmark detection at several hundreds of…
ImViA Laboratory, University of Burgundy（勃艮第大学ImViA实验室）；CHU Dijon（第戎大学医院）；CGFL；Institut Curie（居里研究所）
In this paper, we propose a new deep learning framework for an automatic myocardial infarction evaluation from clinical information and delayed enhancement-MRI (DE-MRI). The proposed framework addresses two tasks. The first task is automatic detection of myocardial contours, the infarcted area, the no-reflow area, and the left ventricular cavity from a short-axis DE-MRI series. It employs two segmentation neural networks. The first network is used to segment the anatomical structures such as the myocardium and left ventricular cavity. The second network is used to segment the pathological area…
GE Vingmed Ultrasound, GE Healthcare（通用电气医疗集团GE Vingmed超声部门）；University of Oslo（奥斯陆大学）；Norwegian Computing Center（挪威计算中心）
Two-dimensional echocardiography (2DE) measurements of left ventricle (LV) dimensions are highly significant markers of several cardiovascular diseases. These measurements are often used in clinical care despite suffering from large variability between observers. This variability is due to the challenging nature of accurately finding the correct temporal and spatial location of measurement endpoints in ultrasound images. These images often contain fuzzy boundaries and varying reflection patterns between frames. In this work, we present a convolutional neural network (CNN) based approach to aut…
Zhengzhou University of Light Industry（郑州轻工业大学）；University of Southern Mississippi（南密西西比大学）；Michigan Technological University（密歇根理工大学）；New York Presbyterian Queens Hospital（纽约长老会皇后医院）；The First Affiliated Hospital of Nanjing Medical University（南京医科大学第一附属医院）
Automatic identification of proper image frames at the end-diastolic (ED) and end-systolic (ES) frames during the review of invasive coronary angiograms (ICA) is important to assess blood flow during a cardiac cycle, reconstruct the 3D arterial anatomy from bi-planar views, and generate the complementary fusion map with myocardial images. The current identification method primarily relies on visual interpretation, making it not only time-consuming but also less reproducible. In this paper, we propose a new method to automatically identify angiographic image frames associated with the ED and ES…
Compared to abstract features, significant objects, so-called landmarks, are a more natural means for vehicle localization and navigation, especially in challenging unstructured environments. The major challenge is to recognize landmarks in various lighting conditions and changing environment (growing vegetation) while only having few training samples available. We propose a new method which leverages Deep Learning as well as model-based methods to overcome the need of a large data set. Using RGB images and light detection and ranging (LiDAR) point clouds, our approach combines state-of-the-ar…
University of California, Los Angeles（加州大学洛杉矶分校）；University of Alberta（阿尔伯塔大学）；Mazankowski Alberta Heart Institute（马赞科夫斯基阿尔伯塔心脏研究所）
This study proposes a fully automated approach for the left atrial segmentation from routine cine long-axis cardiac magnetic resonance image sequences using deep convolutional neural networks and Bayesian filtering. The proposed approach consists of a classification network that automatically detects the type of long-axis sequence and three different convolutional neural network models followed by unscented Kalman filtering (UKF) that delineates the left atrium. Instead of training and predicting all long-axis sequence types together, the proposed approach first identifies the image sequence t…
Anatomical landmarks are a crucial prerequisite for many medical imaging tasks. Usually, the set of landmarks for a given task is predefined by experts. The landmark locations for a given image are then annotated manually or via machine learning methods trained on manual annotations. In this paper, in contrast, we present a method to automatically discover and localize anatomical landmarks in medical images. Specifically, we consider landmarks that attract the visual attention of humans, which we term visually salient landmarks. We illustrate the method for fetal neurosonographic images. First…
Towards a vision foundation model for comprehensive assessment of Cardiac MRI
Siemens Healthineers（西门子医疗）；Klinikum rechts der Isar, Technical University of Munich（慕尼黑工业大学 rechts der Isar 医院）；Siemens Healthineers AG（西门子医疗股份公司）；Imperial College London（伦敦帝国学院）
Amsterdam UMC, University of Amsterdam（阿姆斯特丹大学阿姆斯特丹大学医学中心）；Amsterdam University Medical Center, University of Amsterdam（阿姆斯特丹大学阿姆斯特丹大学医学中心）；University Medical Center Utrecht（乌得勒支大学医学中心）
Segmentation of cardiac anatomical structures in cardiac magnetic resonance images (CMRI) is a prerequisite for automatic diagnosis and prognosis of cardiovascular diseases. To increase robustness and performance of segmentation methods this study combines automatic segmentation and assessment of segmentation uncertainty in CMRI to detect image regions containing local segmentation failures. Three state-of-the-art convolutional neural networks (CNN) were trained to automatically segment cardiac anatomical structures and obtain two measures of predictive uncertainty: entropy and a measure deriv…
Image-guided radiation therapy can benefit from accurate motion tracking by ultrasound imaging, in order to minimize treatment margins and radiate moving anatomical targets, e.g., due to breathing. One way to formulate this tracking problem is the automatic localization of given tracked anatomical landmarks throughout a temporal ultrasound sequence. For this, we herein propose a fully-convolutional Siamese network that learns the similarity between pairs of image regions containing the same landmark. Accordingly, it learns to localize and thus track arbitrary image features, not only predefine…
Cardiac left ventricle (LV) quantification provides a tool for diagnosing cardiac diseases. Automatic calculation of all relevant LV indices from cardiac MR images is an intricate task due to large variations among patients and deformation during the cardiac cycle. Typical methods are based on segmentation of the myocardium or direct regression from MR images. To consider cardiac motion and deformation, recurrent neural networks and spatio-temporal convolutional neural networks (CNNs) have been proposed. We study an approach combining state-of-the-art models and emphasizing transfer learning t…
University Medical Center Utrecht（乌得勒支大学医学中心）；Amsterdam UMC, University of Amsterdam（阿姆斯特丹大学阿姆斯特丹医学中心）；University of Twente（特文特大学）；Wageningen University（瓦赫宁根大学）
In this study, we propose a fast and accurate method to automatically localize anatomical landmarks in medical images. We employ a global-to-local localization approach using fully convolutional neural networks (FCNNs). First, a global FCNN localizes multiple landmarks through the analysis of image patches, performing regression and classification simultaneously. In regression, displacement vectors pointing from the center of image patches towards landmark locations are determined. In classification, presence of landmarks of interest in the patch is established. Global landmark locations are o…
University of Sherbrooke（舍布鲁克大学）；University of Bourgogne Franche-Comte（勃艮第-弗朗什孔泰大学）；CASIS inc.（CASIS公司）；University of Lyon（里昂大学）
Convolutional neural networks (CNN) have had unprecedented success in medical imaging and, in particular, in medical image segmentation. However, despite the fact that segmentation results are closer than ever to the inter-expert variability, CNNs are not immune to producing anatomically inaccurate segmentations, even when built upon a shape prior. In this paper, we present a framework for producing cardiac image segmentation maps that are guaranteed to respect pre-defined anatomical criteria, while remaining within the inter-expert variability. The idea behind our method is to use a well-trai…
The University of Winnipeg（温尼伯大学）；Qatar University（卡塔尔大学）；Hamad Medical Corporation（哈马德医疗公司）
Cardiac imaging known as echocardiography is a non-invasive tool utilized to produce data including images and videos, which cardiologists use to diagnose cardiac abnormalities in general and myocardial infarction (MI) in particular. Echocardiography machines can deliver abundant amounts of data that need to be quickly analyzed by cardiologists to help them make a diagnosis and treat cardiac conditions. However, the acquired data quality varies depending on the acquisition conditions and the patient's responsiveness to the setup instructions. These constraints are challenging to doctors especi…
A versatile foundation model for cine cardiac magnetic resonance image analysis tasks
UCL Hawkes Institute, Department of Medical Physics and Biomedical Engineering, University College London（伦敦大学霍克斯研究所、医学物理与生物医学工程系、伦敦大学学院）；InstaDeep；Department of Computing, Imperial College London（伦敦帝国学院计算机系）；Department of Brain Sciences, Imperial College London（伦敦帝国学院脑科学系）；Institute of Cardiovascular Sciences, University College London（伦敦大学学院心血管科学研究所）；Barts Heart Centre, Barts Health NHS Trust（巴特斯心脏中心、巴特斯健康 NHS信托）
Heart Institute (InCor/HC.FMUSP)（心脏研究所（InCor/HC.FMUSP））
CNN (Convolutional Neural Network) models have been successfully used for segmentation of the left ventricle (LV) in cardiac MRI (Magnetic Resonance Imaging), providing clinical measurements. In practice, two questions arise with deployment of CNNs: 1) when is it better to use a shallow model instead of a deeper one? 2) how the size of a dataset might change the network performance? We propose a framework to answer them, by experimenting with deep and shallow versions of three U-Net families, trained from scratch in six subsets varying from 100 to 10,000 images, different network sizes, learni…
In recent years, convolutional neural networks have demonstrated promising performance in a variety of medical image segmentation tasks. However, when a trained segmentation model is deployed into the real clinical world, the model may not perform optimally. A major challenge is the potential poor-quality segmentations generated due to degraded image quality or domain shift issues. There is a timely need to develop an automated quality control method that can detect poor segmentations and feedback to clinicians. Here we propose a novel deep generative model-based framework for quality control …
Enhancing Alzheimer's Diagnosis: Leveraging Anatomical Landmarks in Graph Convolutional Neural Networks on Tetrahedral Meshes
School of Computing and Augmented Intelligence, Arizona State University, Tempe, AZ, USA（计算与增强智能学院，亚利桑那州立大学）；Amazon AGI, Redmond, WA, USA（亚马逊人工智慧部门）；Banner Alzheimer’s Institute, Phoenix, AZ, USA（贝纳尔德阿尔茨海默病研究所）
In this work, we develop a neural network-based method to convert a noisy motion signal generated from segmenting rebinned list-mode cardiac SPECT images, to that of a high-quality surrogate signal, such as those seen from external motion tracking systems (EMTs). This synthetic surrogate will be used as input to our pre-existing motion correction technique developed for EMT surrogate signals. In our method, we test two families of neural networks to translate noisy internal motion to external surrogate: 1) fully connected networks and 2) convolutional neural networks. Our dataset consists of c…
WarpPINN-fibers: improved cardiac strain estimation from cine-MR with physics-informed neural networks
Millennium Institute for Intelligent Healthcare Engineering, iHEALTH；Department of Mechanical；Metallurgical Engineering, School of Engineering, Pontificia Universidad Cat\'olica de Chile, Santiago, Chile；Institute for Biological；Medical Engineering, Schools of Engineering, Medicine
University of Leeds（利兹大学）；University of Oxford（牛津大学）；Queen Mary University of London（伦敦玛丽女王大学）；Barts Health NHS Trust（巴茨健康国民保健制度信托基金）
Large prospective epidemiological studies acquire cardiovascular magnetic resonance (CMR) images for pre-symptomatic populations and follow these over time. To support this approach, fully automatic large-scale 3D analysis is essential. In this work, we propose a novel deep neural network using both CMR images and patient metadata to directly predict cardiac shape parameters. The proposed method uses the promising ability of statistical shape models to simplify shape complexity and variability together with the advantages of convolutional neural networks for the extraction of solid visual feat…
CONICET（阿根廷国家科学与技术研究理事会）；The Bariloche Atomic Center（巴里洛切原子中心）；Instituto Balseiro（巴尔塞罗研究所）；Universidad Nacional de Cuyo（库约国立大学）；Sanatorio San Carlos（圣卡洛斯疗养院）；National Atomic Energy Commission (Comisión Nacional de Energía Atómica, CNEA)（国家原子能委员会（CNEA））
Background: Artificial intelligence techniques have shown great potential in cardiology, especially in quantifying cardiac biventricular function, volume, mass, and ejection fraction (EF). However, its use in clinical practice is not straightforward due to its poor reproducibility with cases from daily practice, among other reasons. Objectives: To validate a new artificial intelligence tool in order to quantify the cardiac biventricular function (volume, mass, and EF). To analyze its robustness in the clinical area, and the computational times compared with conventional methods. Methods: A tot…
