Reliable Tuberculosis Detection using Chest X-ray with Deep Learning, Segmentation and Visualization
University of Dhaka(达卡大学);Qatar University(卡塔尔大学);Bangabandhu Sheikh Mujib Medical University(邦班杜·谢赫·穆吉布医科大学);Hamad General Hospital(哈马德综合医院);Weill Cornell Medicine – Qatar(威尔康奈尔医学院卡塔尔分校);Universiti Kebangsaan Malaysia(马来西亚国民大学);North South University(北南大学);College of Engineering, Qatar University(卡塔尔大学工程学院)
Tawsifur Rahman, Amith Khandakar, Muhammad Abdul Kadir, Khandaker R. Islam, Khandaker F. Islam, Rashid Mazhar, Tahir Hamid, Mohammad T. Islam, Zaid B. Mahbub, M… 展开作者
Tawsifur Rahman, Amith Khandakar, Muhammad Abdul Kadir, Khandaker R. Islam, Khandaker F. Islam, Rashid Mazhar, Tahir Hamid, Mohammad T. Islam, Zaid B. Mahbub, Mohamed Arselene Ayari, Muhammad E. H. Chowdhury
Tuberculosis (TB) is a chronic lung disease that occurs due to bacterial infection and is one of the top 10 leading causes of death. Accurate and early detection of TB is very important, otherwise, it could be life-threatening. In this work, we have detected TB reliably from the chest X-ray images using image pre-processing, data augmentation, image segmentation, and deep-learning classification techniques. Several public databases were used to create a database of 700 TB infected and 3500 normal chest X-ray images for this study. Nine different deep CNNs (ResNet18, ResNet50, ResNet101, ChexNet, InceptionV3, Vgg19, DenseNet201, SqueezeNet, and MobileNet), which were used for transfer learning from their pre-trained initial weights and trained, validated and tested for classifying TB and non-TB normal cases. Three different experiments were carried out in this work: segmentation of X-ray images using two different U-net models, classification using X-ray images, and segmented lung images. The accuracy, precision, sensitivity, F1-score, specificity in the detection of tuberculosis using X-ray images were 97.07 %, 97.34 %, 97.07 %, 97.14 % and 97.36 % respectively. However, segmented lungs for the classification outperformed than whole X-ray image-based classification and accuracy, precision, sensitivity, F1-score, specificity were 99.9 %, 99.91 %, 99.9 %, 99.9 %, and 99.52 % respectively. The paper also used a visualization technique to confirm that CNN learns dominantly from the segmented lung regions results in higher detection accuracy. The proposed method with state-of-the-art performance can be useful in the computer-aided faster diagnosis of tuberculosis.
Vellore Institute of Technology, Chennai(韦洛尔理工学院(金奈校区))
Tuberculosis is an infectious disease that is leading to the death of millions of people across the world. The mortality rate of this disease is high in patients suffering from immuno-compromised disorders. The early diagnosis of this disease can save lives and can avoid further complications. But the diagnosis of TB is a very complex task. The standard diagnostic tests still rely on traditional procedures developed in the last century. These procedures are slow and expensive. So this paper presents an automatic approach for the diagnosis of TB from posteroanterior chest x-rays. This is a two-…
National Library of Medicine, National Institutes of Health(美国国立医学图书馆,美国国立卫生研究院)
Deep learning (DL) models are state-of-the-art in segmenting anatomical and disease regions of interest (ROIs) in medical images. Particularly, a large number of DL-based techniques have been reported using chest X-rays (CXRs). However, these models are reportedly trained on reduced image resolutions for reasons related to the lack of computational resources. Literature is sparse in discussing the optimal image resolution to train these models for segmenting the Tuberculosis (TB)-consistent lesions in CXRs. In this study, we investigated the performance variations using an Inception-V3 UNet mo…
National Library of Medicine, National Institutes of Health(美国国立卫生研究院国家医学图书馆)
Automated segmentation of tuberculosis (TB)-consistent lesions in chest X-rays (CXRs) using deep learning (DL) methods can help reduce radiologist effort, supplement clinical decision-making, and potentially result in improved patient treatment. The majority of works in the literature discuss training automatic segmentation models using coarse bounding box annotations. However, the granularity of the bounding box annotation could result in the inclusion of a considerable fraction of false positives and negatives at the pixel level that may adversely impact overall semantic segmentation perform…
Indian Institute of Technology Delhi(印度德里理工学院);Teleradiology Solutions(远程放射学解决方案公司);CSIR-Institute of Genomics and Integrative Biology(CSIR基因组学与整合生物学研究所);Christian Medical College(基督教医学院)
Background and Objective: Tuberculosis (TB) is a significant public health issue and a leading cause of death worldwide. Millions of deaths can be averted by early diagnosis and successful treatment of TB patients. Automated diagnosis of TB holds vast potential to assist medical experts in expediting and improving its diagnosis, especially in developing countries like India, where there is a shortage of trained medical experts and radiologists. To date, several deep learning based methods for automated detection of TB from chest radiographs have been proposed. However, the performance of a few…
Tuberculosis (TB) is a contagious bacterial airborne disease, and is one of the top 10 causes of death worldwide. According to the World Health Organization (WHO), around 1.8 billion people are infected with TB and 1.6 million deaths were reported in 2018. More importantly,95% of cases and deaths were from developing countries. Yet, TB is a completely curable disease through early diagnosis. To achieve this goal one of the key requirements is efficient utilization of existing diagnostic technologies, among which chest X-ray is the first line of diagnostic tool used for screening for active TB.…
National Library of Medicine, National Institutes of Health(美国国立卫生研究院国家医学图书馆);Clinical Center, National Institutes of Health(美国国立卫生研究院临床中心);Saint Louis University(圣路易斯大学)
Chest X-rays are the most commonly performed diagnostic examination to detect cardiopulmonary abnormalities. However, the presence of bony structures such as ribs and clavicles can obscure subtle abnormalities, resulting in diagnostic errors. This study aims to build a deep learning-based bone suppression model that identifies and removes these occluding bony structures in frontal CXRs to assist in reducing errors in radiological interpretation, including DL workflows, related to detecting manifestations consistent with tuberculosis (TB). Several bone suppression models with various deep archi…
Advancing Diagnostic Precision: Leveraging Machine Learning Techniques for Accurate Detection of Covid-19, Pneumonia, and Tuberculosis in Chest X-Ray Images
Concordia University(康考迪亚大学);North South University(北南大学)
Pretraining has sparked groundswell of interest in deep learning workflows to learn from limited data and improve generalization. While this is common for 2D image classification tasks, its application to 3D medical imaging tasks like chest CT interpretation is limited. We explore the idea of whether pretraining a model on realistic videos could improve performance rather than training the model from scratch, intended for tuberculosis type classification from chest CT scans. To incorporate both spatial and temporal features, we develop a hybrid convolutional neural network (CNN) and recurrent …
Chulalongkorn University(朱拉隆功大学);Thai Health AI Foundation(泰国健康人工智能基金会);Johns Hopkins Bloomberg School of Public Health(约翰斯·霍普金斯大学布隆伯格公共卫生学院)
Machine learning has been an emerging tool for various aspects of infectious diseases including tuberculosis surveillance and detection. However, WHO provided no recommendations on using computer-aided tuberculosis detection software because of the small number of studies, methodological limitations, and limited generalizability of the findings. To quantify the generalizability of the machine-learning model, we developed a Deep Convolutional Neural Network (DCNN) model using a TB-specific CXR dataset of one population (National Library of Medicine Shenzhen No.3 Hospital) and tested it with non…
Radboud University Medical Center(拉德堡德大学医学中心);Community Health Solutions(社区健康解决方案公司);Interactive Research and Development(互动研究与发展机构);The Indus Health Network(印度河健康网络);Thirona(Thirona公司);Universal Delft Ltd.(代尔夫特环球有限公司)
There is a growing interest in the automated analysis of chest X-Ray (CXR) as a sensitive and inexpensive means of screening susceptible populations for pulmonary tuberculosis. In this work we evaluate the latest version of CAD4TB, a commercial software platform designed for this purpose. Version 6 of CAD4TB was released in 2018 and is here tested on a fully independent dataset of 5565 CXR images with GeneXpert (Xpert) sputum test results available (854 Xpert positive subjects). A subset of 500 subjects (50% Xpert positive) was reviewed and annotated by 5 expert observers independently to obta…
The use of ImageNet pre-trained networks is becoming widespread in the medical imaging community. It enables training on small datasets, commonly available in medical imaging tasks. The recent emergence of a large Chest X-ray dataset opened the possibility for learning features that are specific to the X-ray analysis task. In this work, we demonstrate that the features learned allow for better classification results for the problem of Tuberculosis detection and enable generalization to an unseen dataset. To accomplish the task of feature learning, we train a DenseNet-121 CNN on 112K images fro…
Deep learning-based lung segmentation and automatic regional template in chest X-ray images for pediatric tuberculosis
Universidad Politécnica de Madrid(马德里理工大学);CIBER-BBN(生物工程、生物材料与纳米医学网络研究中心);Children’s National Hospital(国家儿童医院);George Washington University School of Medicine(乔治华盛顿大学医学院);ISGlobal(巴塞罗那全球健康研究所);Hospital Clínic(巴塞罗那临床医院);Universitat de Barcelona(巴塞罗那大学);Stellenbosch University(斯泰伦博斯大学)
The results of chest X-ray (CXR) analysis of 2D images to get the statistically reliable predictions (availability of tuberculosis) by computer-aided diagnosis (CADx) on the basis of deep learning are presented. They demonstrate the efficiency of lung segmentation, lossless and lossy data augmentation for CADx of tuberculosis by deep convolutional neural network (CNN) applied to the small and not well-balanced dataset even. CNN demonstrates ability to train (despite overfitting) on the pre-processed dataset obtained after lung segmentation in contrast to the original not-segmented dataset. Los…
University of Waterloo(滑铁卢大学);Waterloo Artificial Intelligence Institute(滑铁卢人工智能研究所);DarwinAI Corp.(DarwinAI公司);Niagara Health(尼亚加拉健康中心);McMaster University(麦克马斯特大学);Thunder Bay Regional Health Sciences Centre(桑德贝地区健康科学中心);Northern Ontario School of Medicine(北安大略医学院)
Tuberculosis (TB) remains a global health problem, and is the leading cause of death from an infectious disease. A crucial step in the treatment of tuberculosis is screening high risk populations and the early detection of the disease, with chest x-ray (CXR) imaging being the most widely-used imaging modality. As such, there has been significant recent interest in artificial intelligence-based TB screening solutions for use in resource-limited scenarios where there is a lack of trained healthcare workers with expertise in CXR interpretation. Motivated by this pressing need and the recent recom…
Stop TB Partnership(遏制结核病伙伴关系);International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b)(孟加拉国国际腹泻病研究中心)
Artificial intelligence (AI) products can be trained to recognize tuberculosis (TB)-related abnormalities on chest radiographs. Various AI products are available commercially, yet there is lack of evidence on how their performance compared with each other and with radiologists. We evaluated five AI software products for screening and triaging TB using a large dataset that had not been used to train any commercial AI products. Individuals (>=15 years old) presenting to three TB screening centers in Dhaka, Bangladesh, were recruited consecutively. All CXR were read independently by a group of th…
Google Health(谷歌健康);Advanced Clinical(先进临床);Apollo Radiology International(阿波罗国际放射学);Center of Infectious Disease Research in Zambia(赞比亚传染病研究中心);Sibanye Stillwater(斯班耶-斯蒂尔沃特);Clickmedix
Tuberculosis (TB) is a top-10 cause of death worldwide. Though the WHO recommends chest radiographs (CXRs) for TB screening, the limited availability of CXR interpretation is a barrier. We trained a deep learning system (DLS) to detect active pulmonary TB using CXRs from 9 countries across Africa, Asia, and Europe, and utilized large-scale CXR pretraining, attention pooling, and noisy student semi-supervised learning. Evaluation was on (1) a combined test set spanning China, India, US, and Zambia, and (2) an independent mining population in South Africa. Given WHO targets of 90% sensitivity an…
Bharti School of Telecommunications Technology & Management, Indian Institute of Technology Delhi(印度理工学院德里分校巴蒂电信技术与管理学院);Teleradiology Solutions(远程放射学解决方案公司);CSIR-Institute of Genomics and Integrative Biology(CSIR基因组学与整合生物学研究所);Christian Medical College, Vellore(韦洛尔基督教医学院)
A chest radiograph, commonly called chest x-ray (CxR), plays a vital role in the diagnosis of various lung diseases, such as lung cancer, tuberculosis, pneumonia, and many more. Automated segmentation of the lungs is an important step to design a computer-aided diagnostic tool for examination of a CxR. Precise lung segmentation is considered extremely challenging because of variance in the shape of the lung caused by health issues, age, and gender. The proposed work investigates the use of an efficient deep convolutional neural network for accurate segmentation of lungs from CxR. We attempt an…
Henan Provincial Chest Hospital(河南省胸科医院);Harbin Institute of Technology(哈尔滨工业大学);Huiying Medical Technology (Beijing) Co., Ltd.(慧影医疗科技(北京)有限公司)
Objective: We propose an end-to-end CNN-based locating model for pulmonary tuberculosis (TB) diagnosis in radiographs. This model makes full use of chest radiograph (X-ray) for its improved accessibility, reduced cost and high accuracy for TB disease. Methods: Several specialized improvements are proposed for detection task in medical field. A false positive (FP) restrictor head is introduced for FP reduction. Anchor-oriented network heads is proposed in the position regression section. An optimization of loss function is designed for hard example mining. Results: The experimental results show…
AI Research Group, Institute of Mathematics(人工智能研究组,数学研究所);Eötvös Loránd University(罗兰大学)
Chest X-ray is the most common test among medical imaging modalities. It is applied for detection and differentiation of, among others, lung cancer, tuberculosis, and pneumonia, the last with importance due to the COVID-19 disease. Integrating computer-aided detection methods into the radiologist diagnostic pipeline, greatly reduces the doctors' workload, increasing reliability and quantitative analysis. Here we present a novel deep learning approach for lung segmentation, a basic, but arduous task in the diagnostic pipeline. Our method uses state-of-the-art fully convolutional neural networks…
Comparative Analysis of Deep Learning Architectures for Multi-Disease Classification of Single-Label Chest X-rays
Department of Computer Science, College of Science, Charmo University(查莫大学计算机科学系,科学学院);Department of Software Engineering, University of Raparin(拉帕林大学软件工程系)
Radboud University Medical Center(拉德堡德大学医学中心);Netherlands Cancer Institute (NKI)(荷兰癌症研究所);Z 2 Sky Technologies Inc.(Z 2 Sky 技术公司);Johns Hopkins University(约翰斯·霍普金斯大学);University of Science and Technology of China(中国科学技术大学);Institute of Computing Technology, CAS(中国科学院计算技术研究所)
Clinical evidence has shown that rib-suppressed chest X-rays (CXRs) can improve the reliability of pulmonary disease diagnosis. However, previous approaches on generating rib-suppressed CXR face challenges in preserving details and eliminating rib residues. We hereby propose a GAN-based disentanglement learning framework called Rib Suppression GAN, or RSGAN, to perform rib suppression by utilizing the anatomical knowledge embedded in unpaired computed tomography (CT) images. In this approach, we employ a residual map to characterize the intensity difference between CXR and the corresponding ri…
Institute for Neuro- and Bioinformatics, University of Lübeck(吕贝克大学神经与生物信息学研究所);Department of Mathematics, Faculty of Science, South Valley University(南谷大学理学院数学系)
This paper explores how well deep learning models trained on chest CT images can diagnose COVID-19 infected people in a fast and automated process. To this end, we adopt advanced deep network architectures and propose a transfer learning strategy using custom-sized input tailored for each deep architecture to achieve the best performance. We conduct extensive sets of experiments on two CT image datasets, namely the SARS-CoV-2 CT-scan and the COVID19-CT. The obtained results show superior performances for our models compared with previous studies, where our best models achieve average accuracy,…
Monash University(莫纳什大学);IBM Research Australia(IBM澳大利亚研究院)
The widely used ChestX-ray14 dataset addresses an important medical image classification problem and has the following caveats: 1) many lung pathologies are visually similar, 2) a variant of diseases including lung cancer, tuberculosis, and pneumonia are present in a single scan, i.e. multiple labels and 3) The incidence of healthy images is much larger than diseased samples, creating imbalanced data. These properties are common in medical domain. Existing literature uses stateof- the-art DensetNet/Resnet models being transfer learned where output neurons of the networks are trained for indivi…
Contrastive learning is a form of self-supervision that can leverage unlabeled data to produce pretrained models. While contrastive learning has demonstrated promising results on natural image classification tasks, its application to medical imaging tasks like chest X-ray interpretation has been limited. In this work, we propose MoCo-CXR, which is an adaptation of the contrastive learning method Momentum Contrast (MoCo), to produce models with better representations and initializations for the detection of pathologies in chest X-rays. In detecting pleural effusion, we find that linear models t…
Artificial intelligence (AI) and specifically machine learning is making inroads into number of fields. Machine learning is replacing and/or complementing humans in a certain type of domain to make systems perform tasks more efficiently and independently. Healthcare is a worthy domain to merge with AI and Machine learning to get things to work smoother and efficiently. The X-ray based detection and classification of diseases related to chest is much needed in this modern era due to the low number of quality radiologists. This thesis focuses on the classification of Pneumonia and Tuberculosis t…
Google Health, Google(谷歌健康,谷歌);Apollo Radiology International(阿波罗国际放射医学);Northwestern Medicine(西北医学)
Chest radiography (CXR) is the most widely-used thoracic clinical imaging modality and is crucial for guiding the management of cardiothoracic conditions. The detection of specific CXR findings has been the main focus of several artificial intelligence (AI) systems. However, the wide range of possible CXR abnormalities makes it impractical to build specific systems to detect every possible condition. In this work, we developed and evaluated an AI system to classify CXRs as normal or abnormal. For development, we used a de-identified dataset of 248,445 patients from a multi-city hospital networ…
The infection of respiratory coronavirus disease 2019 (COVID-19) starts with the upper respiratory tract and as the virus grows, the infection can progress to lungs and develop pneumonia. The conventional way of COVID-19 diagnosis is reverse transcription polymerase chain reaction (RT-PCR), which is less sensitive during early stages; especially if the patient is asymptomatic, which may further cause more severe pneumonia. In this context, several deep learning models have been proposed to identify pulmonary infections using publicly available chest X-ray (CXR) image datasets for early diagnos…
University of Chittagong(吉大港大学);Charles Sturt University(查尔斯特大学)
The COVID-19 pandemic continues to severely undermine the prosperity of the global health system. To combat this pandemic, effective screening techniques for infected patients are indispensable. There is no doubt that the use of chest X-ray images for radiological assessment is one of the essential screening techniques. Some of the early studies revealed that the patient's chest X-ray images showed abnormalities, which is natural for patients infected with COVID-19. In this paper, we proposed a parallel-dilated convolutional neural network (CNN) based COVID-19 detection system from chest x-ray…
Chest X-Rays (CXRs) are widely used for diagnosing abnormalities in the heart and lung area. Automatically detecting these abnormalities with high accuracy could greatly enhance real world diagnosis processes. Lack of standard publicly available dataset and benchmark studies, however, makes it difficult to compare various detection methods. In order to overcome these difficulties, we have used a publicly available Indiana CXR, JSRT and Shenzhen dataset and studied the performance of known deep convolutional network (DCN) architectures on different abnormalities. We find that the same DCN archi…
Technical University of Munich(慕尼黑工业大学);Stanford University(斯坦福大学)
Interpreting chest radiograph, a.ka. chest x-ray, images is a necessary and crucial diagnostic tool used by medical professionals to detect and identify many diseases that may plague a patient. Although the images themselves contain a wealth of valuable information, their usefulness may be limited by how well they are interpreted, especially when the reviewing radiologist may be fatigued or when or an experienced radiologist is unavailable. Research in the use of deep learning models to analyze chest radiographs yielded impressive results where, in some instances, the models outperformed pract…
Scientific Computing and Imaging Institute, University of Utah(犹他大学科学计算与成像研究所);Department of Radiology and Imaging Sciences, University of Utah(犹他大学放射学与影像科学系)
Knowledge of what spatial elements of medical images deep learning methods use as evidence is important for model interpretability, trustiness, and validation. There is a lack of such techniques for models in regression tasks. We propose a method, called visualization for regression with a generative adversarial network (VR-GAN), for formulating adversarial training specifically for datasets containing regression target values characterizing disease severity. We use a conditional generative adversarial network where the generator attempts to learn to shift the output of a regressor through cre…
New York University(纽约大学);The University of Alabama(阿拉巴马大学);Université Quisqueya(基斯克亚大学);NYU Grossman School of Medicine(纽约大学格罗斯曼医学院)
Chest computed tomography (CT) imaging adds valuable insight in the diagnosis and management of pulmonary infectious diseases, like tuberculosis (TB). However, due to the cost and resource limitations, only X-ray images may be available for initial diagnosis or follow up comparison imaging during treatment. Due to their projective nature, X-rays images may be more difficult to interpret by clinicians. The lack of publicly available paired X-ray and CT image datasets makes it challenging to train a 3D reconstruction model. In addition, Chest X-ray radiology may rely on different device modaliti…
Dedan Kimathi University of Technology(德丹·基马蒂理工大学)
Chest X-rays remains to be the most common imaging modality used to diagnose lung diseases. However, they necessitate the interpretation of experts (radiologists and pulmonologists), who are few. This review paper investigates the use of deep transfer learning techniques to detect COVID-19, pneumonia, and tuberculosis in chest X-ray (CXR) images. It provides an overview of current state-of-the-art CXR image classification techniques and discusses the challenges and opportunities in applying transfer learning to this domain. The paper provides a thorough examination of recent research studies t…
Purpose: Considering several patients screened due to COVID-19 pandemic, computer-aided detection has strong potential in assisting clinical workflow efficiency and reducing the incidence of infections among radiologists and healthcare providers. Since many confirmed COVID-19 cases present radiological findings of pneumonia, radiologic examinations can be useful for fast detection. Therefore, chest radiography can be used to fast screen COVID-19 during the patient triage, thereby determining the priority of patient's care to help saturated medical facilities in a pandemic situation. Methods: I…
VRVis Zentrum für Virtual Reality und Visualisierung Forschungs-GmbH(VRVis虚拟现实与可视化研究中心有限公司);Agfa NV(爱克发股份有限公司);Antwerp University Hospital(安特卫普大学医院);University of Antwerp(安特卫普大学)
To facilitate both the detection and the interpretation of findings in chest X-rays, comparison with a previous image of the same patient is very valuable to radiologists. Today, the most common approach for deep learning methods to automatically inspect chest X-rays disregards the patient history and classifies only single images as normal or abnormal. Nevertheless, several methods for assisting in the task of comparison through image registration have been proposed in the past. However, as we illustrate, they tend to miss specific types of pathological changes like cardiomegaly and effusion.…
In the field of eXplainable AI (XAI), robust "blackbox" algorithms such as Convolutional Neural Networks (CNNs) are known for making high prediction performance. However, the ability to explain and interpret these algorithms still require innovation in the understanding of influential and, more importantly, explainable features that directly or indirectly impact the performance of predictivity. A number of methods existing in literature focus on visualization techniques but the concepts of explainability and interpretability still require rigorous definition. In view of the above needs, this p…
Qatar University(卡塔尔大学);Universiti Kebangsaan Malaysia(马来西亚国民大学)
Novel Coronavirus disease (COVID-19) is an extremely contagious and quickly spreading Coronavirus infestation. Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), which outbreak in 2002 and 2011, and the current COVID-19 pandemic are all from the same family of coronavirus. This work aims to classify COVID-19, SARS, and MERS chest X-ray (CXR) images using deep Convolutional Neural Networks (CNNs). A unique database was created, so-called QU-COVID-family, consisting of 423 COVID-19, 144 MERS, and 134 SARS CXR images. Besides, a robust COVID-19 recognition syste…
Stamford University(斯坦福德大学);Charles Sturt University(查尔斯斯特大学);University of Chittagong(吉大港大学)
Due to the limited availability and high cost of the reverse transcription-polymerase chain reaction (RT-PCR) test, many studies have proposed machine learning techniques for detecting COVID-19 from medical imaging. The purpose of this study is to systematically review, assess, and synthesize research articles that have used different machine learning techniques to detect and diagnose COVID-19 from chest X-ray and CT scan images. A structured literature search was conducted in the relevant bibliographic databases to ensure that the survey solely centered on reproducible and high-quality resear…
From CNN to Transformer: A Review of Medical Image Segmentation Models
University of Electronic Science and Technology of China(电子科技大学);Deyang People’s Hospital(德阳市人民医院);Sichuan Provincial People’s Hospital(四川省人民医院);Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital(中国科学院四川转化医学研究医院)
University of Sheffield(谢菲尔德大学);Insigneo Institute for in-silico Medicine(Insigneo计算机医学研究所);University of Oxford(牛津大学);University of Lincoln(林肯大学);University of Glasgow(格拉斯哥大学);University of Brighton(布莱顿大学);Nantong University(南通大学)
The global pandemic of COVID-19 is continuing to have a significant effect on the well-being of global population, increasing the demand for rapid testing, diagnosis, and treatment. Along with COVID-19, other etiologies of pneumonia and tuberculosis constitute additional challenges to the medical system. In this regard, the objective of this work is to develop a new deep transfer learning pipeline to diagnose patients with COVID-19, pneumonia, and tuberculosis, based on chest x-ray images. We observed in some instances DenseNet and Resnet have orthogonal performances. In our proposed model, we…