Explainable COVID-19 Detection Using Chest CT Scans and Deep Learning
Institute for Neuro- and Bioinformatics, University of Lübeck（吕贝克大学神经与生物信息学研究所）；Department of Mathematics, Faculty of Science, South Valley University（南谷大学理学院数学系）
Hammam Alshazly, Christoph Linse, Erhardt Barth, Thomas Martinetz
This paper explores how well deep learning models trained on chest CT images can diagnose COVID-19 infected people in a fast and automated process. To this end, we adopt advanced deep network architectures and propose a transfer learning strategy using custom-sized input tailored for each deep architecture to achieve the best performance. We conduct extensive sets of experiments on two CT image datasets, namely the SARS-CoV-2 CT-scan and the COVID19-CT. The obtained results show superior performances for our models compared with previous studies, where our best models achieve average accuracy, precision, sensitivity, specificity and F1 score of 99.4%, 99.6%, 99.8%, 99.6% and 99.4% on the SARS-CoV-2 dataset; and 92.9%, 91.3%, 93.7%, 92.2% and 92.5% on the COVID19-CT dataset, respectively. Furthermore, we apply two visualization techniques to provide visual explanations for the models' predictions. The visualizations show well-separated clusters for CT images of COVID-19 from other lung diseases, and accurate localizations of the COVID-19 associated regions.
The Coronavirus Disease 2019 (COVID-19) has spread globally and caused serious damage. Chest X-ray images are widely used for COVID-19 diagnosis and the Artificial Intelligence method can increase efficiency and accuracy. In the Challenge of Chest XR COVID-19 detection in Ethics and Explainability for Responsible Data Science (EE-RDS) conference 2021, we proposed a method that combined Swin Transformer and Transformer in Transformer to classify chest X-ray images as three classes: COVID-19, Pneumonia, and Normal (healthy) and achieved 0.9475 accuracies on the test set.
University of Chittagong（吉大港大学）；Charles Sturt University（查尔斯特大学）
This paper proposed an ensemble of deep convolutional neural networks (CNN) based on EfficientNet, named ECOVNet, to detect COVID-19 using a large chest X-ray data set. At first, the open-access large chest X-ray collection is augmented, and then ImageNet pre-trained weights for EfficientNet is transferred with some customized fine-tuning top layers that are trained, followed by an ensemble of model snapshots to classify chest X-rays corresponding to COVID-19, normal, and pneumonia. The predictions of the model snapshots, which are created during a single training, are combined through two ens…
3D CT-scan base on chest is one of the controversial topisc of the researcher nowadays. There are many tasks to diagnose the disease through CT-scan images, include Covid19. In this paper, we propose a method that custom and combine Deep Neural Network to classify the series of 3D CT-scans chest images. In our methods, we experiment with 2 backbones is DenseNet 121 and ResNet 101. In this proposal, we separate the experiment into 2 tasks, one is for 2 backbones combination of ResNet and DenseNet, one is for DenseNet backbones combination.
Sabaragamuwa University of Sri Lanka（斯里兰卡萨伯勒格穆沃大学）
The novel coronavirus variant, which is also widely known as COVID-19, is currently a common threat to all humans across the world. Effective recognition of COVID-19 using advanced machine learning methods is a timely need. Although many sophisticated approaches have been proposed in the recent past, they still struggle to achieve expected performances in recognizing COVID-19 using chest X-ray images. In addition, the majority of them are involved with the complex pre-processing task, which is often challenging and time-consuming. Meanwhile, deep networks are end-to-end and have shown promisin…
Concordia University（康考迪亚大学）；Sunnybrook Health Sciences Centre（桑尼布鲁克健康科学中心）；University of Toronto（多伦多大学）；McGill University（麦吉尔大学）
Novel Coronavirus disease (COVID-19) is a highly contagious respiratory infection that has had devastating effects on the world. Recently, new COVID-19 variants are emerging making the situation more challenging and threatening. Evaluation and quantification of COVID-19 lung abnormalities based on chest Computed Tomography (CT) scans can help determining the disease stage, efficiently allocating limited healthcare resources, and making informed treatment decisions. During pandemic era, however, visual assessment and quantification of COVID-19 lung lesions by expert radiologists become expensiv…
Saratoga High School（萨拉托加高中）；Stanford University（斯坦福大学）
Chest X-rays of coronavirus disease 2019 (COVID-19) patients are frequently obtained to determine the extent of lung disease and are a valuable source of data for creating artificial intelligence models. Most work to date assessing disease severity on chest imaging has focused on segmenting computed tomography (CT) images; however, given that CTs are performed much less frequently than chest X-rays for COVID-19 patients, automated lung lesion segmentation on chest X-rays could be clinically valuable. There currently exists a universal shortage of chest X-rays with ground truth COVID-19 lung le…
National Institute of Technology Delhi（德里国家技术学院）；Indian Institute of Technology, Roorkee（印度理工学院鲁尔基分校）
Biomedical imaging analysis combined with artificial intelligence (AI) methods has proven to be quite valuable in order to diagnose COVID-19. So far, various classification models have been used for diagnosing COVID-19. However, classification of patients based on their severity level is not yet analyzed. In this work, we classify covid images based on the severity of the infection. First, we pre-process the X-ray images using a median filter and histogram equalization. Enhanced X-ray images are then augmented using SMOTE technique for achieving a balanced dataset. Pre-trained Resnet50, VGG16 …
Pakistan Institute of Engineering & Applied Sciences（巴基斯坦工程与应用科学学院）；PIEAS Artificial Intelligence Center (PAIC)（PIEAS人工智能中心）；Center for Mathematical Sciences（数学科学中心）
COVID-19 is a highly contagious respiratory infection that has affected a large population across the world and continues with its devastating consequences. It is imperative to detect COVID-19 at the earliest to limit the span of infection. In this work, a new classification technique CB-STM-RENet based on deep Convolutional Neural Network (CNN) and Channel Boosting is proposed for the screening of COVID-19 in chest X-Rays. In this connection, to learn the COVID-19 specific radiographic patterns, a new convolution block based on split-transform-merge (STM) is developed. This new block systemat…
University of Waterloo（滑铁卢大学）；Waterloo AI Institute（滑铁卢人工智能研究院）；DarwinAI Corp.（达尔文人工智能公司）
After more than two years since the beginning of the COVID-19 pandemic, the pressure of this crisis continues to devastate globally. The use of chest X-ray (CXR) imaging as a complementary screening strategy to RT-PCR testing is not only prevailing but has greatly increased due to its routine clinical use for respiratory complaints. Thus far, many visual perception models have been proposed for COVID-19 screening based on CXR imaging. Nevertheless, the accuracy and the generalization capacity of these models are very much dependent on the diversity and the size of the dataset they were trained…
Semnan University（塞姆南大学）；Amirkabir University of Technology（阿米尔卡比尔理工大学）
The Coronavirus was detected in Wuhan, China in late 2019 and then led to a pandemic with a rapid worldwide outbreak. The number of infected people has been swiftly increasing since then. Therefore, in this study, an attempt was made to propose a new and efficient method for automatic diagnosis of Corona disease from X-ray images using Deep Neural Networks (DNNs). In the proposed method, the DensNet169 was used to extract the features of the patients' Chest X-Ray (CXR) images. The extracted features were given to a feature selection algorithm (i.e., ANOVA) to select a number of them. Finally, …
Kobe University Graduate School of Medicine（神户大学医学院）；Kyoto University Graduate School of Medicine（京都大学医学院）
Purpose: This study aimed to develop and validate computer-aided diagnosis (CXDx) system for classification between COVID-19 pneumonia, non-COVID-19 pneumonia, and the healthy on chest X-ray (CXR) images. Materials and Methods: From two public datasets, 1248 CXR images were obtained, which included 215, 533, and 500 CXR images of COVID-19 pneumonia patients, non-COVID-19 pneumonia patients, and the healthy samples. The proposed CADx system utilized VGG16 as a pre-trained model and combination of conventional method and mixup as data augmentation methods. Other types of pre-trained models were …
This technical report proposes the use of a deep convolutional neural network as a preliminary diagnostic method in the analysis of chest computed tomography images from patients with symptoms of Severe Acute Respiratory Syndrome (SARS) and suspected COVID-19 disease, especially on occasions when the delay of the RT-PCR result and the absence of urgent care could result in serious temporary, long-term, or permanent health damage. The model was trained on 83,391 images, validated on 15,297, and tested on 22,185 figures, achieving an F1-Score of 98%, 97.59% in Cohen's Kappa, 98.4% in Accuracy, a…
Middlesex University（密德萨斯大学）；Newham University Hospital（纽汉大学医院）；Barts Health NHS Trust（巴茨健康国民医疗服务信托）
This paper is responding to the MIA-COV19 challenge to classify COVID from non-COVID based on CT lung images. The COVID-19 virus has devastated the world in the last eighteen months by infecting more than 182 million people and causing over 3.9 million deaths. The overarching aim is to predict the diagnosis of the COVID-19 virus from chest radiographs, through the development of explainable vision transformer deep learning techniques, leading to population screening in a more rapid, accurate and transparent way. In this competition, there are 5381 three-dimensional (3D) datasets in total, incl…
COMSATS University Islamabad（伊斯兰堡COMSATS大学）；Bacha Khan University（巴查汗大学）；Chung-Ang University（中央大学）；University of Malaya（马来亚大学）；University Malaysia Sabah（马来西亚沙巴大学）；Institute of Space Technology（空间技术研究所）
The ongoing COVID-19 pandemic has already taken millions of lives and damaged economies across the globe. Most COVID-19 deaths and economic losses are reported from densely crowded cities. It is comprehensible that the effective control and prevention of epidemic/pandemic infectious diseases is vital. According to WHO, testing and diagnosis is the best strategy to control pandemics. Scientists worldwide are attempting to develop various innovative and cost-efficient methods to speed up the testing process. This paper comprehensively evaluates the applicability of the recent top ten state-of-th…
COVID-19 is a global pandemic, and detecting them is a momentous task for medical professionals today due to its rapid mutations. Current methods of examining chest X-rays and CT scan requires profound knowledge and are time consuming, which suggests that it shrinks the precious time of medical practitioners when people's lives are at stake. This study tries to assist this process by achieving state-of-the-art performance in classifying chest X-rays by fine-tuning Vision Transformer(ViT). The proposed approach uses pretrained models, fine-tuned for detecting the presence of COVID-19 disease on…
The 2019 novel coronavirus (COVID-19) has spread rapidly all over the world and it is affecting the whole society. The current gold standard test for screening COVID-19 patients is the polymerase chain reaction test. However, the COVID-19 test kits are not widely available and time-consuming. Thus, as an alternative, chest X-rays are being considered for quick screening. Since the presentation of COVID-19 in chest X-rays is varied in features and specialization in reading COVID-19 chest X-rays are required thus limiting its use for diagnosis. To address this challenge of reading chest X-rays b…
Cupertino High School（库比蒂诺高中）；Stanford University（斯坦福大学）
Coronavirus disease 2019 (COVID-19) is the highly contagious illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The standard diagnostic testing procedure for COVID-19 is testing a nasopharyngeal swab for SARS-CoV-2 nucleic acid using a real-time polymerase chain reaction (PCR), which can take multiple days to provide a diagnosis. Another widespread form of testing is rapid antigen testing, which has a low sensitivity compared to PCR, but is favored for its quick diagnosis time of usually 15-30 minutes. Patients who test positive for COVID-19 demonstrate diffuse alv…
University of South Florida（南佛罗里达大学）；University of California, San Francisco（加利福尼亚大学旧金山分校）
Testing for COVID-19 has been unable to keep up with the demand. Further, the false negative rate is projected to be as high as 30% and test results can take some time to obtain. X-ray machines are widely available and provide images for diagnosis quickly. This paper explores how useful chest X-ray images can be in diagnosing COVID-19 disease. We have obtained 122 chest X-rays of COVID-19 and over 4,000 chest X-rays of viral and bacterial pneumonia. A pretrained deep convolutional neural network has been tuned on 102 COVID-19 cases and 102 other pneumonia cases in a 10-fold cross validation. T…
University of Saskatchewan（萨斯喀彻温大学）；International Road Dynamics（国际道路动力学公司）；National Institute of Technology, Trichy（特里奇国家理工学院）
One of the primary clinical observations for screening the infectious by the novel coronavirus is capturing a chest x-ray image. In most of the patients, a chest x-ray contains abnormalities, such as consolidation, which are the results of COVID-19 viral pneumonia. In this study, research is conducted on efficiently detecting imaging features of this type of pneumonia using deep convolutional neural networks in a large dataset. It is demonstrated that simple models, alongside the majority of pretrained networks in the literature, focus on irrelevant features for decision-making. In this paper,…
São Paulo State University (UNESP)（圣保罗州立大学（UNESP））
COVID-19 quickly became a global pandemic after only four months of its first detection. It is crucial to detect this disease as soon as possible to decrease its spread. The use of chest X-ray (CXR) images became an effective screening strategy, complementary to the reverse transcription-polymerase chain reaction (RT-PCR). Convolutional neural networks (CNNs) are often used for automatic image classification and they can be very useful in CXR diagnostics. In this paper, 21 different CNN architectures are tested and compared in the task of identifying COVID-19 in CXR images. They were applied t…
COVID-19, also known as Novel Coronavirus Disease, is a highly contagious disease that first surfaced in China in late 2019. SARS-CoV-2 is a coronavirus that belongs to the vast family of coronaviruses that causes this disease. The sickness originally appeared in Wuhan, China in December 2019 and quickly spread to over 213 nations, becoming a global pandemic. Fever, dry cough, and tiredness are the most typical COVID-19 symptoms. Aches, pains, and difficulty breathing are some of the other symptoms that patients may face. The majority of these symptoms are indicators of respiratory infections …
University of Turin（都灵大学）；Azienda Ospedaliera Città della Salute e della Scienza Presidio Molinette（健康与科学城医院莫利内特分院）；AOU San Luigi Gonzaga（圣路易吉·贡扎加大学医院）
Early screening of patients is a critical issue in order to assess immediate and fast responses against the spread of COVID-19. The use of nasopharyngeal swabs has been considered the most viable approach; however, the result is not immediate or, in the case of fast exams, sufficiently accurate. Using Chest X-Ray (CXR) imaging for early screening potentially provides faster and more accurate response; however, diagnosing COVID from CXRs is hard and we should rely on deep learning support, whose decision process is, on the other hand, "black-boxed" and, for such reason, untrustworthy. We propos…
IIIT-Delhi（印度德里信息技术学院）；IIT Jodhpur（印度焦特布尔理工学院）；Ashwini Hospital（阿什维尼医院）；Ramakant Heart Care Centre（拉马坎特心脏护理中心）；TeleRadiology Solutions（远程放射学解决方案公司）
With increasing number of COVID-19 cases globally, all the countries are ramping up the testing numbers. While the RT-PCR kits are available in sufficient quantity in several countries, others are facing challenges with limited availability of testing kits and processing centers in remote areas. This has motivated researchers to find alternate methods of testing which are reliable, easily accessible and faster. Chest X-Ray is one of the modalities that is gaining acceptance as a screening modality. Towards this direction, the paper has two primary contributions. Firstly, we present the COVID-1…
Ecole Nationale des Télécommunications et des Technologies de l'Information et de la Communication (ENSTTIC)（国立电信与信息通信技术学院）；University of Djillali Liabes（吉拉利·利亚贝斯大学）；Konya Technical University（科尼亚技术大学）
In medical practice, the contribution of information technology can be considerable. Most of these practices include the images that medical assistance uses to identify different pathologies of the human body. One of them is X-ray images which cover much of our work in this paper. Chest x-rays have played an important role in Covid 19 identification and diagnosis. The Covid 19 virus has been declared a global pandemic since 2020 after the first case found in Wuhan China in December 2019. Our goal in this project is to be able to classify different chest X-ray images containing Covid 19, viral …
Amirkabir University of Technology（阿米尔卡比尔理工大学）；Semnan University（塞姆南大学）
In late 2019 and after COVID-19 pandemic in the world, many researchers and scholars have tried to provide methods for detection of COVID-19 cases. Accordingly, this study focused on identifying COVID-19 cases from chest X-ray images. In this paper, a novel approach to diagnosing coronavirus disease from X-ray images was proposed. In the proposed method, DenseNet169 deep neural network was used to extract the features of X-ray images taken from the patients' chest and the extracted features were then given as input to the Extreme Gradient Boosting (XGBoost) algorithm so that it could perform t…
University of Michigan（密歇根大学）；Henry Ford Health System（亨利·福特医疗系统）；Molecular Medicine Institute（分子医学研究所）
CXR-Net is a two-module Artificial Intelligence pipeline for the quick detection of SARS-CoV-2 from chest X-rays (CXRs). Module 1 was trained on a public dataset of 6395 CXRs with radiologist annotated lung contours to generate masks of the lungs that overlap the heart and large vasa. Module 2 is a hybrid convnet in which the first convolutional layer with learned coefficients is replaced by a layer with fixed coefficients provided by the Wavelet Scattering Transform (WST). Module 2 takes as inputs the patients CXRs and corresponding lung masks calculated by Module 1, and produces as outputs a…
National Institute of Technology Delhi（德里国家理工学院）；Indian Institute of Technology, Roorkee（鲁尔基印度理工学院）
Background and Objective: During pandemics, the use of artificial intelligence (AI) approaches combined with biomedical science play a significant role in reducing the burden on the healthcare systems and physicians. The rapid increment in cases of COVID-19 has led to an increase in demand for hospital beds and other medical equipment. However, since medical facilities are limited, it is recommended to diagnose patients as per the severity of the infection. Keeping this in mind, we share our research in detecting COVID-19 as well as assessing its severity using chest-CT scans and Deep Learning…
Tampere University（坦佩雷大学）；Qatar University（卡塔尔大学）；Reem Medical Center（里姆医疗中心）；Hamad Medical Corporation Hospital（哈马德医疗公司医院）
Coronavirus disease 2019 (COVID-19) has rapidly become a global health concern after its first known detection in December 2019. As a result, accurate and reliable advance warning system for the early diagnosis of COVID-19 has now become a priority. The detection of COVID-19 in early stages is not a straightforward task from chest X-ray images according to expert medical doctors because the traces of the infection are visible only when the disease has progressed to a moderate or severe stage. In this study, our first aim is to evaluate the ability of recent \textit{state-of-the-art} Machine Le…
Universidad de Antioquia（安蒂奥基亚大学）；Johns Hopkins University（约翰斯·霍普金斯大学）；Universidad Politécnica de Madrid（马德里理工大学）
Current standard protocols used in the clinic for diagnosing COVID-19 include molecular or antigen tests, generally complemented by a plain chest X-Ray. The combined analysis aims to reduce the significant number of false negatives of these tests, but also to provide complementary evidence about the presence and severity of the disease. However, the procedure is not free of errors, and the interpretation of the chest X-Ray is only restricted to radiologists due to its complexity. With the long term goal to provide new evidence for the diagnosis, this paper presents an evaluation of different m…
Andalusian Research Institute in Data Science and Computational Intelligence（安达卢西亚数据科学与计算智能研究所）；University of Granada（格拉纳达大学）；University of Vigo（维戈大学）；University of Alicante（阿利坎特大学）
Currently, Coronavirus disease (COVID-19), one of the most infectious diseases in the 21st century, is diagnosed using RT-PCR testing, CT scans and/or Chest X-Ray (CXR) images. CT (Computed Tomography) scanners and RT-PCR testing are not available in most medical centers and hence in many cases CXR images become the most time/cost effective tool for assisting clinicians in making decisions. Deep learning neural networks have a great potential for building COVID-19 triage systems and detecting COVID-19 patients, especially patients with low severity. Unfortunately, current databases do not allo…
University of Waterloo（滑铁卢大学）；DarwinAI Corp.（DarwinAI公司）；Niagara Health（尼亚加拉医疗）；McMaster University（麦克马斯特大学）；Thunder Bay Regional Health Sciences Centre（桑德贝地区健康科学中心）；Northern Ontario School of Medicine（北部安大略医学院）
The world is still struggling in controlling and containing the spread of the COVID-19 pandemic caused by the SARS-CoV-2 virus. The medical conditions associated with SARS-CoV-2 infections have resulted in a surge in the number of patients at clinics and hospitals, leading to a significantly increased strain on healthcare resources. As such, an important part of managing and handling patients with SARS-CoV-2 infections within the clinical workflow is severity assessment, which is often conducted with the use of chest x-ray (CXR) images. In this work, we introduce COVID-Net CXR-S, a convolution…
Technical University of Munich（慕尼黑工业大学）；Stanford University（斯坦福大学）
Interpreting chest radiograph, a.ka. chest x-ray, images is a necessary and crucial diagnostic tool used by medical professionals to detect and identify many diseases that may plague a patient. Although the images themselves contain a wealth of valuable information, their usefulness may be limited by how well they are interpreted, especially when the reviewing radiologist may be fatigued or when or an experienced radiologist is unavailable. Research in the use of deep learning models to analyze chest radiographs yielded impressive results where, in some instances, the models outperformed pract…
Mohamed bin Zayed University of Artificial Intelligence（穆罕默德·本·扎耶德人工智能大学）
Quick and accurate diagnosis is of paramount importance to mitigate the effects of COVID-19 infection, particularly for severe cases. Enormous effort has been put towards developing deep learning methods to classify and detect COVID-19 infections from chest radiography images. However, recently some questions have been raised surrounding the clinical viability and effectiveness of such methods. In this work, we investigate the impact of multi-task learning (classification and segmentation) on the ability of CNNs to differentiate between various appearances of COVID-19 infections in the lung. W…
In 2019, the entire world is facing a situation of health emergency due to a newly emerged coronavirus (COVID-19). Almost 196 countries are affected by covid-19, while USA, Italy, China, Spain, Iran, and France have the maximum active cases of COVID-19. The issues, medical and healthcare departments are facing in delay of detecting the COVID-19. Several artificial intelligence based system are designed for the automatic detection of COVID-19 using chest x-rays. In this article we will discuss the different approaches used for the detection of COVID-19 and the challenges we are facing. It is ma…
The coronavirus continues to disrupt our everyday lives as it spreads at an exponential rate. It needs to be detected quickly in order to quarantine positive patients so as to avoid further spread. This work proposes a new convolutional neural network (CNN) architecture called 'slow Encoding CNN. The proposed model's best performance wrt Sensitivity, Positive Predictive Value (PPV) found to be SP=0.67, PP=0.98, SN=0.96, and PN=0.52 on AI AGAINST COVID19 - Screening X-ray images for COVID-19 Infections competition's test data samples. SP and PP stand for the Sensitivity and PPV of the COVID-19 …
In this study, a dataset of X-ray images from patients with common viral pneumonia, bacterial pneumonia, confirmed Covid-19 disease was utilized for the automatic detection of the Coronavirus disease. The point of the investigation is to assess the exhibition of cutting edge convolutional neural system structures proposed over the ongoing years for clinical picture order. In particular, the system called Transfer Learning was received. With transfer learning, the location of different variations from the norm in little clinical picture datasets is a reachable objective, regularly yielding amaz…
There are multiple papers published about different AI models for the COVID-19 diagnosis with promising results. Unfortunately according to the reviews many of the papers do not reach the level of sophistication needed for a clinically usable model. In this paper I go through multiple review papers, guidelines, and other relevant material in order to generate more comprehensive requirements for the future papers proposing a AI based diagnosis of the COVID-19 from chest X-ray data (CXR). Main findings are that a clinically usable AI needs to have an extremely good documentation, comprehensive s…
One of the critical tools for early detection and subsequent evaluation of the incidence of lung diseases is chest radiography. This study presents a real-world implementation of a convolutional neural network (CNN) based Carebot Covid app to detect COVID-19 from chest X-ray (CXR) images. Our proposed model takes the form of a simple and intuitive application. Used CNN can be deployed as a STOW-RS prediction endpoint for direct implementation into DICOM viewers. The results of this study show that the deep learning model based on DenseNet and ResNet architecture can detect SARS-CoV-2 from CXR …
Indian Institute of Technology Delhi（德里印度理工学院）；University of Bath（巴斯大学）；Indian Institute of Technology Kanpur（坎普尔印度理工学院）；All India Institute of Medical Sciences Delhi（德里全印度医学科学研究所）
The exponential increase in COVID-19 patients is overwhelming healthcare systems across the world. With limited testing kits, it is impossible for every patient with respiratory illness to be tested using conventional techniques (RT-PCR). The tests also have long turn-around time, and limited sensitivity. Detecting possible COVID-19 infections on Chest X-Ray may help quarantine high risk patients while test results are awaited. X-Ray machines are already available in most healthcare systems, and with most modern X-Ray systems already digitized, there is no transportation time involved for the …
Sierra Research S.L（塞拉研究有限公司）；Universidad de Alicante（阿利坎特大学）；Medbravo（Medbravo医疗公司）；Fundación para el Fomento de la Investigación Sanitario y Biomédica de la Comunidad Valenciana（瓦伦西亚自治区卫生与生物医学研究促进基金会）；Hospital San Juan de Alicante（阿利坎特圣胡安医院）；Universidad Miguel Hernández（米格尔·埃尔南德斯大学）
In this work we present a method for the detection of radiological findings, their location and differential diagnoses from chest x-rays. Unlike prior works that focus on the detection of few pathologies, we use a hierarchical taxonomy mapped to the Unified Medical Language System (UMLS) terminology to identify 189 radiological findings, 22 differential diagnosis and 122 anatomic locations, including ground glass opacities, infiltrates, consolidations and other radiological findings compatible with COVID-19. We train the system on one large database of 92,594 frontal chest x-rays (AP or PA, st…
Semi-supervised learning (SSL) leverages both labeled and unlabeled data for training models when the labeled data is limited and the unlabeled data is vast. Frequently, the unlabeled data is more widely available than the labeled data, hence this data is used to improve the level of generalization of a model when the labeled data is scarce. However, in real-world settings unlabeled data might depict a different distribution than the labeled dataset distribution. This is known as distribution mismatch. Such problem generally occurs when the source of unlabeled data is different from the labele…
Qatar University（卡塔尔大学）；Bangladesh University of Engineering and Technology（孟加拉国工程技术大学）；Reem Medical Center（Reem医疗中心）；Hamad General Hospital（哈马德综合医院）；Weill Cornell Medicine - Qatar（威尔康奈尔医学院卡塔尔分校）
Coronavirus disease 2019 (COVID-19) has been the main agenda of the whole world, since it came into sight in December 2019 as it has significantly affected the world economy and healthcare system. Given the effects of COVID-19 on pulmonary tissues, chest radiographic imaging has become a necessity for screening and monitoring the disease. Numerous studies have proposed Deep Learning approaches for the automatic diagnosis of COVID-19. Although these methods achieved astonishing performance in detection, they have used limited chest X-ray (CXR) repositories for evaluation, usually with a few hun…
Indian Institute of Information Technology, Sri City, Chittoor（印度信息技术学院，斯里城，奇图尔）；Indian Institute of Information Technology, Allahabad（印度信息技术学院，阿拉哈巴德）
Covid-19 global pandemic continues to devastate health care systems across the world. At present, the Covid-19 testing is costly and time-consuming. Chest X-Ray (CXR) testing can be a fast, scalable, and non-invasive method. The existing methods suffer due to the limited CXR samples available from Covid-19. Thus, inspired by the limitations of the open-source work in this field, we propose attention guided contrastive CNN architecture (AC-CovidNet) for Covid-19 detection in CXR images. The proposed method learns the robust and discriminative features with the help of contrastive loss. Moreover…
Warsaw University of Technology（华沙理工大学）；Sano Centre for Computational Medicine（萨诺计算医学中心）；Jagiellonian University（雅盖隆大学）；Tooploox
A critical step in the fight against COVID-19, which continues to have a catastrophic impact on peoples lives, is the effective screening of patients presented in the clinics with severe COVID-19 symptoms. Chest radiography is one of the promising screening approaches. Many studies reported detecting COVID-19 in chest X-rays accurately using deep learning. A serious limitation of many published approaches is insufficient attention paid to explaining decisions made by deep learning models. Using explainable artificial intelligence methods, we demonstrate that model decisions may rely on confoun…
Universidade do Vale do Rio dos Sinos（瓦莱杜里奥杜斯辛诺斯大学）
Early identification of patients with COVID-19 is essential to enable adequate treatment and to reduce the burden on the health system. The gold standard for COVID-19 detection is the use of RT-PCR tests. However, due to the high demand for tests, these can take days or even weeks in some regions of Brazil. Thus, an alternative for detecting COVID-19 is the analysis of Digital Chest X-rays (XR). Changes due to COVID-19 can be detected in XR, even in asymptomatic patients. In this context, models based on deep learning have great potential to be used as support systems for diagnosis or as scree…
University of Chittagong（吉大港大学）；Charles Sturt University（查尔斯特大学）
The COVID-19 pandemic continues to severely undermine the prosperity of the global health system. To combat this pandemic, effective screening techniques for infected patients are indispensable. There is no doubt that the use of chest X-ray images for radiological assessment is one of the essential screening techniques. Some of the early studies revealed that the patient's chest X-ray images showed abnormalities, which is natural for patients infected with COVID-19. In this paper, we proposed a parallel-dilated convolutional neural network (CNN) based COVID-19 detection system from chest x-ray…
Spreading of COVID-19 virus has increased the efforts to provide testing kits. Not only the preparation of these kits had been hard, rare, and expensive but also using them is another issue. Results have shown that these kits take some crucial time to recognize the virus, in addition to the fact that they encounter with 30% loss. In this paper, we have studied the usage of x-ray pictures which are ubiquitous, for the classification of COVID-19 chest Xray images, by the existing convolutional neural networks (CNNs). We intend to train chest x-rays of infected and not infected ones with differen…
University of Leeds（利兹大学）；Leeds Teaching Hospitals NHS Trust（利兹教学医院 NHS 信托基金）
Since the emergence of COVID-19, deep learning models have been developed to identify COVID-19 from chest X-rays. With little to no direct access to hospital data, the AI community relies heavily on public data comprising numerous data sources. Model performance results have been exceptional when training and testing on open-source data, surpassing the reported capabilities of AI in pneumonia-detection prior to the COVID-19 outbreak. In this study impactful models are trained on a widely used open-source data and tested on an external test set and a hospital dataset, for the task of classifyin…
Beijing University of Posts and Telecommunications（北京邮电大学）
The COVID-19 epidemic has become a major safety and health threat worldwide. Imaging diagnosis is one of the most effective ways to screen COVID-19. This project utilizes several open-source or public datasets to present an open-source dataset of COVID-19 CXRs, named COVID-19-CXR-Dataset, and introduces a deep convolutional neural network model. The model validates on 740 test images and achieves 87.3% accuracy, 89.67 % precision, and 84.46% recall, and correctly classifies 98 out of 100 COVID-19 x-ray images in test set with more than 81% prediction probability under the condition of 95% conf…
School of Computing and Information Technology, University of Wollongong（卧龙岗大学计算与信息技术学院）
The Coronavirus Disease 2019 (COVID-19) is affecting increasingly large number of people worldwide, posing significant stress to the health care systems. Early and accurate diagnosis of COVID-19 is critical in screening of infected patients and breaking the person-to-person transmission. Chest X-ray (CXR) based computer-aided diagnosis of COVID-19 using deep learning becomes a promising solution to this end. However, the diverse and various radiographic features of COVID-19 make it challenging, especially when considering each CXR scan typically only generates one single image. Data scarcity i…
Classification of COVID-19 in Chest X-ray Images Using Fusion of Deep Features and LightGBM
Amirkabir University of Technology（阿米尔卡比尔理工大学）；Semnan University（塞姆南大学）；University of New Mexico（新墨西哥大学）；Technical and Vocational University (TVU)（技术与职业大学（TVU））
National Center for Biotechnology Information (NCBI)（美国国家生物技术信息中心）；National Library of Medicine (NLM)（美国国家医学图书馆）；National Institutes of Health (NIH)（美国国立卫生研究院）；Weill Cornell Medicine（威尔康奈尔医学院）；University of Texas at Arlington（德克萨斯大学阿灵顿分校）
The latest threat to global health is the COVID-19 outbreak. Although there exist large datasets of chest X-rays (CXR) and computed tomography (CT) scans, few COVID-19 image collections are currently available due to patient privacy. At the same time, there is a rapid growth of COVID-19-relevant articles in the biomedical literature. Here, we present COVID-19-CT-CXR, a public database of COVID-19 CXR and CT images, which are automatically extracted from COVID-19-relevant articles from the PubMed Central Open Access (PMC-OA) Subset. We extracted figures, associated captions, and relevant figure…
Amirkabir University of Technology（阿米尔卡比尔理工大学）；Semnan University（塞姆南大学）
The new coronavirus (known as COVID-19) was first identified in Wuhan and quickly spread worldwide, wreaking havoc on the economy and people's everyday lives. Fever, cough, sore throat, headache, exhaustion, muscular aches, and difficulty breathing are all typical symptoms of COVID-19. A reliable detection technique is needed to identify affected individuals and care for them in the early stages of COVID-19 and reduce the virus's transmission. The most accessible method for COVID-19 identification is RT-PCR; however, due to its time commitment and false-negative results, alternative options mu…
Universidad Autónoma de Manizales（马尼萨莱斯自治大学）；Universidad Nacional de Colombia（哥伦比亚国立大学）
There is a necessity to develop affordable, and reliable diagnostic tools, which allow containing the COVID-19 spreading. Machine Learning (ML) algorithms have been proposed to design support decision-making systems to assess chest X-ray images, which have proven to be useful to detect and evaluate disease progression. Many research articles are published around this subject, which makes it difficult to identify the best approaches for future work. This paper presents a systematic review of ML applied to COVID-19 detection using chest X-ray images, aiming to offer a baseline for researchers in…
