Significance: Imaging neural activity in myelinated tissue using optical coherence tomography (OCT) creates new possibilities for functional imaging in the peripheral and central nervous systems. Aim: To investigate changes in OCT images in response to evoked neural activity in sciatic nerve of rat in vitro. Approach: M-scans were obtained on peripheral nerves of rat using a swept source polarisation sensitive OCT system, while a nerve cuff acquired electrical neural recordings. From a total of 10 subjects: 3 had no stimulation (controls), 3 had paw stimulation, and 4 had nerve stimulation. Changes in the OCT signal intensity, phase retardation, phase, and frequency spectra were calculated for each subject and reference samples of a mirror and microspheres in solution. Results: Observed changes in intensity in 3 paw stimulation and 2 nerve stimulation subjects and changes in frequency spectra amplitude in 2 paw stimulation subjects were above the reference noise level and were temporally consistent with osmotic swelling from ion currents during neural activity. Conclusion: Light scattering changes produced by osmotic swelling, which have previously been characterised in squid and crab nerve, are also thought to occur in myelinated fibres on a scale which is detectable using OCT
Variation is the Norm: Brain State Dynamics Evoked By Emotional Video Clips
Northeastern University(东北大学);Victoria University of Wellington(惠灵顿维多利亚大学);University of Miami(迈阿密大学);University of Arizona(亚利桑那大学);Dartmouth College(达特茅斯学院);Massachusetts General Hospital(麻省总医院)
Inferring brain plasticity rule under long-term stimulation with structured recurrent dynamics
Southern University of Science and Technology(南方科技大学);Center for Neurocognition and Social Behavior, Institute of Artificial Intelligence, SUAT(深圳大学人工智能学院神经认知与社会行为中心);Shenzhen Loop Area Institute(深圳河套学院)
Input correlations impede suppression of chaos and learning in balanced rate networks
Zuckerman Mind, Brain, Behavior Institute, Columbia University(哥伦比亚大学祖克曼心智、大脑与行为研究所);The Abdus Salam International Centre for Theoretical Physics(阿卜杜勒·萨拉姆国际理论物理中心);Institute of Genetics, University of Bonn(波恩大学遗传学研究所)
A Transformer-based deep neural network model for SSVEP classification
Southwest University of Science and Technology(西南科技大学);University of Electronic Science and Technology of China(电子科技大学);Nanyang Technological University(南洋理工大学)