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arXiv 2004.05725cs.SIphysics.soc-phq-bio.PE
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具有间接传播联系和有限接触信息的动态网络上的疫苗接种策略

Vaccination strategies on dynamic networks with indirect transmission links and limited contact information

Md Shahzamal, Raja Jurdak, Bernard Mans, Frank de Hoog, Dean Paini

摘要:

传染病仍然是现代社会的主要全球负担,每年造成1300万人死亡。降低传染病发病率和死亡率的一种方法是通过预防性或有针对性的疫苗接种。然而,目前的疫苗接种策略依赖于难以获得且成本高昂的高度特异性的个体接触信息,以识别有影响力的传播个体。目前的方法也只注重个人之间的直接接触传播,而忽视了间接传播,即病原体可以在一个感染个体和一个易感个体之间传播,这些个体在短时间内访问同一地点而不见面。本文提出了一种新的疫苗接种策略,依赖于粗粒度的接触信息,直接和间接,可以很容易和有效地收集。我们的策略不是跟踪个人的确切接触程度,而是使用人们访问的地方类型来估计个人的接触程度范围,考虑直接和间接接触。我们进行了广泛的模拟,以评估我们的战略相比,最先进的疫苗接种策略的性能。结果表明,我们的策略实现了与Oracle方法相当的性能,并且在考虑间接链接时优于所有现有策略。

英文摘要:

Infectious diseases are still a major global burden for modern society causing 13 million deaths annually. One way to reduce the morbidity and mortality rates from infectious diseases is through preventative or targeted vaccinations. Current vaccination strategies, however, rely on the highly specific individual contact information that is difficult and costly to obtain, in order to identify influential spreading individuals. Current approaches also focus only on direct contacts between individuals for spreading, and disregard indirect transmission where a pathogen can spread between one infected individual and one susceptible individual that visit the same location within a short time-frame without meeting. This paper presents a novel vaccination strategy that relies on coarse-grained contact information, both direct and indirect, that can be easily and efficiently collected. Rather than tracking exact contact degrees of individuals, our strategy uses the types of places people visit to estimate a range of contact degrees for individuals, considering both direct and indirect contacts. We conduct extensive simulations to evaluate the performance of our strategy in comparison to the state of the art's vaccination strategies. Results show that our strategy achieves comparable performance to the oracle approach and outperforms all existing strategies when considering indirect links.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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