We use a combination of extreme value theory, survival analysis and computer-intensive methods to analyze the mortality of Italian and French semi-supercentenarians for whom there are validated records. After accounting for the effects of the sampling frame, there appears to be a constant rate of mortality beyond age 108 years and no difference between countries and cohorts. These findings are consistent with previous work based on the International Database on Longevity and suggest that any physical upper bound for humans is so large that it is unlikely to be approached. There is no evidence of differences in survival between women and men after age 108 in the Italian data and the International Database on Longevity; however survival is lower for men in the French data.
A Hierarchical Multilevel Inference Framework for Structural Cardiovascular Risk Modeling: County-Scale Analysis of Cardiovascular Mortality in Ohio and Pennsylvania (1999-2020)
Howard University（霍华德大学）；UC Riverside（加州大学河滨分校）；California Institute of Technology（加州理工学院）；Dalian University of Technology（大连理工大学）
BACKGROUND. The majority of countries in Africa and nearly one third of all countries require mortality models to infer complete age schedules of mortality, required for population estimates, projections/forecasts and many other tasks in demography and epidemiology. Models that relate child mortality to mortality at other ages are important because all countries have measures of child mortality. OBJECTIVE. 1) Design a general model for age-specific mortality that provides a standard way to relate covariates to age-specific mortality. 2) Calibrate that model using the relationship between child…
We propose a probabilistic mortality forecasting model that can be applied to derive forecasts for populations with regular and irregular mortality developments. Our model (1) uses rates of mortality improvement to model dynamic age patterns of mortality change and it can (2) optionally complement the mortality trend of a country of interest with that of at least one reference country. Retrospective mortality forecasts for British and Danish women from 1991 to 2011 suggest that our model can generate smaller forecast errors than other widely accepted approaches like, for instance, the Lee-Cart…
An essential input of annuity pricing is the future retiree mortality. From observed age-specific mortality data, modeling and forecasting can be taken place in two routes. On the one hand, we can first truncate the available data to retiree ages and then produce mortality forecasts based on a partial age-range model. On the other hand, with all available data, we can first apply a full age-range model to produce forecasts and then truncate the mortality forecasts to retiree ages. We investigate the difference in modeling the logarithmic transformation of the central mortality rates between a …
Age-specific mortality improvements are non-uniform, neither across ages nor across time. We propose a two-step procedure to estimate the rates of mortality improvement (RMI) in age-specific death rates (ASDR) at ages 85 and above for ten European countries from 1950 to 2019. In the first step, we smooth the raw death counts and estimate ASDR using four different methods: one parametric (gamma-Gompertz-Makeham), two non-parametric (P-splines and PCLM), and a novel Bayesian procedure to handle fluctuations resulting from ages with zero death counts. We compare the goodness of fit of the four sm…
Age-specific mortality rates are often disaggregated by different attributes, such as sex, state and ethnicity. Forecasting age-specific mortality rates at the national and sub-national levels plays an important role in developing social policy. However, independent forecasts at the sub-national levels may not add up to the forecasts at the national level. To address this issue, we consider reconciling forecasts of age-specific mortality rates, extending the methods of Hyndman et al. (2011) to functional time series, where age is considered as a continuum. The grouped functional time series me…
In order to implement disease-specific interventions in young age groups, policy makers in low- and middle-income countries require timely and accurate estimates of age- and cause-specific child mortality. High quality data is not available in settings where these interventions are most needed, but there is a push to create sample registration systems that collect detailed mortality information. Current methods that estimate mortality from this data employ multistage frameworks without rigorous statistical justification that separately estimate all-cause and cause-specific mortality and are no…
In a recent article in PNAS, Case and Deaton show a figure illustrating "a marked increase in the all-cause mortality of middle-aged white non-Hispanic men and women in the United States between 1999 and 2013." The authors state that their numbers "are not age-adjusted within the 10-y 45-54 age group." They calculated the mortality rate each year by dividing the total number of deaths for the age group by the population of the age group. We suspected an aggregation bias. After adjusting for changes in age composition, we find there is no longer a steady increase in mortality rates for this age…
Forecasts of mortality provide vital information about future populations, with implications for pension and health-care policy as well as for decisions made by private companies about life insurance and annuity pricing. Stochastic mortality forecasts allow the uncertainty in mortality predictions to be taken into consideration when making policy decisions and setting product prices. Longer lifespans imply that forecasts of mortality at ages 90 and above will become more important in such calculations. This paper presents a Bayesian approach to the forecasting of mortality that jointly estimat…
There has been growing interest on forecasting mortality. In this article, we propose a novel dynamic Bayesian approach for modeling and forecasting the age-at-death distribution, focusing on a three-components mixture of a Dirac mass, a Gaussian distribution and a Skew-Normal distribution. According to the specified model, the age-at-death distribution is characterized via seven parameters corresponding to the main aspects of infant, adult and old-age mortality. The proposed approach focuses on coherent modeling of multiple countries, and following a Bayesian approach to inference we allow to…
A spatiotemporal Bayesian hierarchical model of heat-related mortality in Catalonia, Spain (2012--2022): The role of environmental and socioeconomic modifiers
University of Girona（赫罗纳大学）；Universitat de Vic -- Central de Catalunya (UVic-UCC)（维克大学--加泰罗尼亚中部大学）
The United Nations released official probabilistic population projections (PPP) for all countries for the first time in July 2014. These were obtained by projecting the period total fertility rate (TFR) and life expectancy at birth ($e_0$) using Bayesian hierarchical models, yielding a large set of future trajectories of TFR and $e_0$ for all countries and future time periods to 2100, sampled from their joint predictive distribution. Each trajectory was then converted to age-specific mortality and fertility rates, and population was projected using the cohort-component method. This yielded a l…
In this work we present a spatial approach to model and investigate mortality data referenced over a Lexis structure. We decompose the force of mortality into two interpretable components: a Markov random field, smooth with respect to time, age and cohort which explains the main pattern of mortality; and a secondary component of independent shocks, accounting for additional non-smooth mortality. Inference is based on a hierarchical Bayesian approach with Markov chain Monte Carlo computations. We present an extensive application to data from the Human Mortality Database about 37 countries. For …
Widespread population aging has made it critical to understand death rates at old ages. However, studying mortality at old ages is challenging because the data are sparse: numbers of survivors and deaths get smaller and smaller with age. We show how to address this challenge by using principled model selection techniques to empirically evaluate theoretical mortality models. We test nine different theoretical models of old-age death rates by fitting them to 360 high-quality datasets on cohort mortality above age 80. Models that allow for the possibility of decelerating death rates tend to fit b…
Application of some basic notions and statistics of ageing distributions used in mathematical theory of reliability including the Gini-type index is discussed as a methodological tool for investigation of human population ageing and longevity. In opposite to the traditionally used median and mean lifetime, the GTI requires only one calendar year snap-shot data to reveal the population ageing or rejuvenating. The case study illustrating the suggested techniques is based on the Australia 1921 and Australia 2009 mortality data from the Human Mortality Database (http://www.mortality.org)
Age-specific mortality rates are often disaggregated by different attributes, such as sex, state, ethnic group and socioeconomic status. In making social policies and pricing annuity at national and subnational levels, it is important not only to forecast mortality accurately, but also to ensure that forecasts at the subnational level add up to the forecasts at the national level. This motivates recent developments in grouped functional time series methods (Shang and Hyndman, 2017) to reconcile age-specific mortality forecasts. We extend these grouped functional time series forecasting methods…
A robust multilevel functional data method is proposed to forecast age-specific mortality rate and life expectancy for two or more populations in developed countries with high-quality vital registration systems. It uses a robust multilevel functional principal component analysis of aggregate and population-specific data to extract the common trend and population-specific residual trend among populations. This method is applied to age- and sex-specific mortality rate and life expectancy for the United Kingdom from 1922 to 2011, and its forecast accuracy is then further compared with standard mu…
Model averaging combines forecasts obtained from a range of models, and it often produces more accurate forecasts than a forecast from a single model. The crucial part of forecast accuracy improvement in using the model averaging lies in the determination of optimal weights from a finite sample. If the weights are selected sub-optimally, this can affect the accuracy of the model-averaged forecasts. Instead of choosing the optimal weights, we consider trimming a set of models before equally averaging forecasts from the selected superior models. Motivated by Hansen, Lunde and Nason (2011), we ap…
In areas of application, including actuarial science and demography, it is increasingly common to consider a time series of curves; an example of this is age-specific mortality rates observed over a period of years. Given that age can be treated as a discrete or continuous variable, a dimension reduction technique, such as principal component analysis, is often implemented. However, in the presence of moderate to strong temporal dependence, static principal component analysis commonly used for analyzing independent and identically distributed data may not be adequate. As an alternative, we con…
This paper presents a novel approach for modeling mortality rates above age 70 by proposing a mixture-based model. This model is compared to four other widely used models: the Beard, Gompertz, Makeham, and Perks models. Our model can capture the complex behavior of mortality rates at all ages, providing a more accurate representation of the data. To evaluate the performance of our model, we applied it to two countries with different data quality: Japan and Brazil. Our results show that the proposed model outperforms the other models in both countries, particularly in Japan where it obtained an…
When modeling sub-national mortality rates, it is important to incorporate any possible correlation among sub-populations to improve forecast accuracy. Moreover, forecasts at the sub-national level should aggregate consistently across the forecasts at the national level. In this study, we apply a grouped multivariate functional time series to forecast Australian regional and remote age-specific mortality rates and reconcile forecasts in a group structure using various methods. Our proposed method compares favorably to a grouped univariate functional time series forecasting method by comparing …
The decrease in the increase in death rates at old ages is a phenomenon that has repeatedly been discussed in demographic research. While mortality deceleration can be explained in the gamma-Gompertz model as an effect of selection in heterogeneous populations, this phenomenon can be difficult to assess statistically because it relates to the tail of the distribution of the ages at death. By using a focused information criterion (FIC) for model selection, we can directly target model performance at those advanced ages. The gamma-Gompertz model is reduced to the competing Gompertz model without…
We aim to assess the impact of a pandemic data point on the calibration of a stochastic multi-population mortality projection model and its resulting projections for future mortality rates. Throughout the paper we put focus on the Li & Lee mortality model, which has become a standard for projecting mortality in Belgium and the Netherlands. We calibrate this mortality model on annual deaths and exposures at the level of individual ages. This type of mortality data is typically collected, produced and reported with a significant delay of -- for some countries -- several years on a platform such …
Age-disaggregated health data is crucial for effective public health planning and monitoring. Monitoring under-five mortality, for example, requires highly detailed age data since the distribution of potential causes of death varies substantially within the first few years of life. Comparative researchers often have to rely on multiple data sources yet, these sources often have ages aggregated at different levels, making it difficult to combine the data into a single, coherent picture. To address this challenge in the context of under-five cause-specific mortality, we propose a Bayesian approa…
Many investigations have used panel methods to study the relationships between fluctuations in economic activity and mortality. A broad consensus has emerged on the overall procyclical nature of mortality: perhaps counter-intuitively, mortality typically rises above its trend during expansions. This consensus has been tarnished by inconsistent reports on the specific age groups and mortality causes involved. We show that these inconsistencies result, in part, from the trend specifications used in previous panel models. Standard econometric panel analysis involves fitting regression models usin…
Geographic patterns in stroke mortality have been studied as far back as the 1960s, when a region of the southeastern United States became known as the "stroke belt" due to its unusually high rates of stroke mortality. While stroke mortality rates are known to increase exponentially with age, an investigation of spatiotemporal trends by age group at the county-level is daunting due to the preponderance of small population sizes and/or few stroke events by age group. Here, we harness the power of a complex, nonseparable multivariate space-time model which borrows strength across space, time, an…
Coronavirus disease 2019 (COVID-19) is associated with a very high number of casualties in the general population. Assessing the exact magnitude of this number is a non-trivial problem, as relying only on officially reported COVID-19 associated fatalities runs the risk of incurring in several kinds of biases. One of the ways to approach the issue is to compare overall mortality during the pandemic with expected mortality computed using the observed mortality figures of previous years. In this paper, we build on existing methodology and propose two ways to compute expected as well as excess mor…
A multilevel functional data method is adapted for forecasting age-specific mortality for two or more populations in developed countries with high-quality vital registration systems. It uses multilevel functional principal component analysis of aggregate and population-specific data to extract the common trend and population-specific residual trend among populations. If the forecasts of population-specific residual trends do not show a long-term trend, then convergence in forecasts may be achieved. This method is first applied to age- and sex-specific data for the United Kingdom, and its forec…
The original version of Bayesian reconstruction, a method for estimating age-specific fertility, mortality, migration and population counts of the recent past with uncertainty, produced estimates for female-only populations. Here we show how two-sex populations can be similarly reconstructed and probabilistic estimates of various sex ratio quantities obtained. We demonstrate the method by reconstructing the populations of India from 1971 to 2001, Thailand from 1960 to 2000, and Laos from 1985 to 2005. We found evidence that in India, sex ratio at birth exceeded its conventional upper limit of …
Moderation effects and elasticities in compositional regression with a total. Application to Bayesian spatiotemporal modelling of all-cause mortality from environmental stressors
University of Girona（赫罗纳大学）；Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, Instituto de Salud Carlos III（公共卫生与流行病学生物医学研究中心，卡洛斯三世健康研究所）
The study of mortality patterns is a popular research topic in many areas. We are particularly interested in mortality patterns among main causes of death associated with age-gender combinations. We use symbolic data analysis (SDA) and include three dimensions: age, gender, and patterns across main causes of death. In this study, we present an alternative method to identify clusters of EU countries with similar mortality patterns in the young population, while considering comprehensive information on the distribution of deaths among the main causes of death by different age-gender groups. We e…
BACKGROUND. Formal demography has a long history of building simple models of age schedules of demographic quantities, e.g. mortality and fertility rates. These are widely used in demographic methods to manipulate whole age schedules using few parameters. OBJECTIVE. The Singular Value Decomposition (SVD) factorizes a matrix into three matrices with useful properties including the ability to reconstruct the original matrix using many fewer, simple matrices. This work demonstrates how these properties can be exploited to build parsimonious models of whole age schedules of demographic quantities …
