Point process modeling is gaining increasing attention, as point process type data are emerging in numerous scientific applications. In this article, motivated by a neuronal spike trains study, we propose a novel point process regression model, where both the response and the predictor can be a high-dimensional point process. We model the predictor effects through the conditional intensities using a set of basis transferring functions in a convolutional fashion. We organize the corresponding transferring coefficients in the form of a three-way tensor, then impose the low-rank, sparsity, and subgroup structures on this coefficient tensor. These structures help reduce the dimensionality, integrate information across different individual processes, and facilitate the interpretation. We develop a highly scalable optimization algorithm for parameter estimation. We derive the large sample error bound for the recovered coefficient tensor, and establish the subgroup identification consistency, while allowing the dimension of the multivariate point process to diverge. We demonstrate the efficacy of our method through both simulations and a cross-area neuronal spike trains analysis in a sensory cortex study.
There are many data sources available that report related variables of interest that are also referenced over geographic regions and time; however, there are relatively few general statistical methods that one can readily use that incorporate these multivariate-spatio-temporal dependencies. As such, we introduce the multivariate-spatio-temporal mixed effects model (MSTM) to analyze areal data with multivariate-spatio-temporal dependencies. The proposed MSTM extends the notion of Moran's I basis functions to the multivariate-spatio-temporal setting. This extension leads to several methodologica…
I begin my discussion by summarizing the methodology proposed and new distributional results on multivariate log-Gamma derived in the paper. Then, I draw an interesting connection between their work with mean field variational Bayes. Lastly, I make some comments on the simulation results and the performance of the proposed Poisson multivariate spatio-temporal mixed effects model (P-MSTM).
This paper contributes to the multivariate analysis of marked spatio-temporal point process data by introducing different partial point characteristics and extending the spatial dependence graph model formalism. Our approach yields a unified framework for different types of spatio-temporal data including both, purely qualitatively (multivariate) cases and multivariate cases with additional quantitative marks. The proposed graphical model is defined through partial spectral density characteristics, it is highly computationally efficient and reflects the conditional similarity among sets of spat…
We first pursue the study of how hierarchy provides a well-adapted tool for the analysis of change. Then, using a time sequence-constrained hierarchical clustering, we develop the practical aspects of a new approach to wavelet regression. This provides a new way to link hierarchical relationships in a multivariate time series data set with external signals. Violence data from the Colombian conflict in the years 1990 to 2004 is used throughout. We conclude with some proposals for further study on the relationship between social violence and market forces, viz. between the Colombian conflict and…
Multivariate time series (MTS) regression tasks are common in many real-world data mining applications including finance, cybersecurity, energy, healthcare, prognostics, and many others. Due to the tremendous success of deep learning (DL) algorithms in various domains including image recognition and computer vision, researchers started adopting these techniques for solving MTS data mining problems, many of which are targeted for safety-critical and cost-critical applications. Unfortunately, DL algorithms are known for their susceptibility to adversarial examples which also makes the DL regress…
When it comes to datasets with a tremendous amount of predictors, variable reduction techniques such as PCA or FA are often used. In this paper, the elastic net, which lies in between the LASSO method and ridge regression, is used as a variable reduction technique followed by further analysis with multivariate regression. Specifically, a messy only dataset is used to show how it can be 'tidied' up and broken down into sensible subsets using the aforementioned method.
RE-EM tree is a tree-based method that combines the regression tree and the linear mixed effects model for modeling univariate response longitudinal or clustered data. In this paper, we generalize the RE-EM tree method to multivariate response data, by adopting the Multivariate Regression Tree method proposed by De'Ath [2002]. The Multivariate RE-EM tree method estimates a population-level single tree structure that is driven by the multiple responses simultaneously and object-level random effects for each response variable, where correlation between the response variables and between the asso…
We propose a new class of estimators of the multivariate response linear regression coefficient matrix that exploits the assumption that the response and predictors have a joint multivariate Normal distribution. This allows us to indirectly estimate the regression coefficient matrix through shrinkage estimation of the parameters of the inverse regression, or the conditional distribution of the predictors given the responses. We establish a convergence rate bound for estimators in our class and we study two examples. The first example estimator exploits an assumption that the inverse regression…
We propose a goodness-of-fit test for the distribution of errors from a multivariate indirect regression model. The test statistic is based on the Khmaladze transformation of the empirical process of standardized residuals. This goodness-of-fit test is consistent at the root-n rate of convergence, and the test can maintain power against local alternatives converging to the null at a root-n rate.
Much of the research on multiple comparison and simultaneous inference in the past sixty years or so has been for the comparisons of several population means. Spurrier (1999) seems to be the first to study the multiple comparison of several simple linear regression lines by using simultaneous confidence bands. In this paper, the work of Liu et al. (2004) for finite comparisons of several univariate linear regression models by using simultaneous confidence bands has been extended to finite comparison of several multivariate linear regression models by using simultaneous confidence tubes. We sho…
We propose a new prediction method for multivariate linear regression problems where the number of features is less than the sample size but the number of outcomes is extremely large. Many popular procedures, such as penalized regression procedures, require parameter tuning that is computationally untenable in such large-scale problems. We take a different approach, motivated by ideas from simultaneous estimation problems, that performs linear shrinkage on ordinary least squares parameter estimates. Our approach is extremely computationally efficient and tuning-free. We show that it can asympt…
Univariate or multivariate ordinal responses are often assumed to arise from a latent continuous parametric distribution, with covariate effects which enter linearly. We introduce a Bayesian nonparametric modeling approach for univariate and multivariate ordinal regression, which is based on mixture modeling for the joint distribution of latent responses and covariates. The modeling framework enables highly flexible inference for ordinal regression relationships, avoiding assumptions of linearity or additivity in the covariate effects. In standard parametric ordinal regression models, computat…
We develop a new method to fit the multivariate response linear regression model that exploits a parametric link between the regression coefficient matrix and the error covariance matrix. Specifically, we assume that the correlations between entries in the multivariate error random vector are proportional to the cosines of the angles between their corresponding regression coefficient matrix columns, so as the angle between two regression coefficient matrix columns decreases, the correlation between the corresponding errors increases. We highlight two models under which this parameterization ar…
Nonparametric estimators of a regression function with circular response and Rd-valued predictor are considered in this work. Local polynomial type estimators are proposed and studied. Expressions for their asymptotic biases and variances are derived, and some guidelines to select asymptotically local optimal bandwidth matrices are also given. The finite sample behavior of the proposed estimators is assessed through simulations and their performance is also illustrated with a real data set.
Groupwise Predictor Envelope Models for Multivariate Linear Regression
The Institute of Statistical Mathematics（统计数学研究所）；Graduate School of Mathematics, Kyushu University（九州大学大学院数理学府）；Faculty of Mathematics, Kyushu University（九州大学数学部）
We propose a new, nonparametric method for multivariate regression subject to convexity or concavity constraints on the response function. Convexity constraints are common in economics, statistics, operations research, financial engineering and optimization, but there is currently no multivariate method that is computationally feasible for more than a few hundred observations. We introduce Convex Adaptive Partitioning (CAP), which creates a globally convex regression model from locally linear estimates fit on adaptively selected covariate partitions. CAP is computationally efficient, in stark …
This paper proposes a maximum-likelihood approach to jointly estimate marginal conditional quantiles of multivariate response variables in a linear regression framework. We consider a slight reparameterization of the Multivariate Asymmetric Laplace distribution proposed by Kotz et al (2001) and exploit its location-scale mixture representation to implement a new EM algorithm for estimating model parameters. The idea is to extend the link between the Asymmetric Laplace distribution and the well-known univariate quantile regression model to a multivariate context, i.e. when a multivariate depend…
In this paper, we develop a systematic theory for high dimensional analysis of variance in multivariate linear regression, where the dimension and the number of coefficients can both grow with the sample size. We propose a new \emph{U}~type test statistic to test linear hypotheses and establish a high dimensional Gaussian approximation result under fairly mild moment assumptions. Our general framework and theory can be applied to deal with the classical one-way multivariate ANOVA and the nonparametric one-way MANOVA in high dimensions. To implement the test procedure in practice, we introduce …
In this paper, we propose the use of geodesic distances in conjunction with multivariate distance matrix regression, called geometric-MDMR, as a powerful first step analysis method for manifold-valued data. Manifold-valued data is appearing more frequently in the literature from analyses of earthquake to analysing brain patterns. Accounting for the structure of this data increases the complexity of your analysis, but allows for much more interpretable results in terms of the data. To test geometric-MDMR, we develop a method to simulate functional connectivity matrices for fMRI data to perform …
This paper presents a practical and simple fully nonparametric multivariate smoothing procedure that adapts to the underlying smoothness of the true regression function. Our estimator is easily computed by successive application of existing base smoothers (without the need of selecting an optimal smoothing parameter), such as thin-plate spline or kernel smoothers. The resulting smoother has better out of sample predictive capabilities than the underlying base smoother, or competing structurally constrained models (GAM) for small dimension (3 < d < 8) and moderate sample size (n < 800). Moreove…
This paper develops a bias correction scheme for a multivariate normal model under a general parameterization. In the model, the mean vector and the covariance matrix share the same parameters. It includes many important regression models available in the literature as special cases, such as (non)linear regression, errors-in-variables models, and so forth. Moreover, heteroscedastic situations may also be studied within our framework. We derive a general expression for the second-order biases of maximum likelihood estimates of the model parameters and show that it is always possible to obtain t…
We propose a M-quantile regression model for the analysis of multivariate, continuous, longitudinal data. M-quantile regression represents an appealing alternative to standard regression models, as it combines the robustness of quantile and the efficiency of expectile regression, providing a complete picture of the response variable distribution. Discrete, individual-specific, random parameters are used to account for both dependence within the same response recorded at different times and association between different responses observed on the same sample unit at a given time. A suitable para…
This paper studies the inference of the regression coefficient matrix under multivariate response linear regressions in the presence of hidden variables. A novel procedure for constructing confidence intervals of entries of the coefficient matrix is proposed. Our method first utilizes the multivariate nature of the responses by estimating and adjusting the hidden effect to construct an initial estimator of the coefficient matrix. By further deploying a low-dimensional projection procedure to reduce the bias introduced by the regularization in the previous step, a refined estimator is proposed …
Information visualization significantly enhances human perception by graphically representing complex data sets. The variety of visualization designs makes it challenging to efficiently evaluate all possible designs catering to users' preferences and characteristics. Most of existing evaluation methods perform user studies to obtain multivariate qualitative responses from users via questionnaires and interviews. However, these methods cannot support online evaluation of designs as they are often time-consuming. A statistical model is desired to predict users' preferences on visualization desig…
Recently, Su and Cook proposed a dimension reduction technique called the inner envelope which can be substantially more efficient than the original envelope or existing dimension reduction techniques for multivariate regression. However, their technique relied on a linear model with normally distributed error, which may be violated in practice. In this work, we propose a semiparametric variant of the inner envelope that does not rely on the linear model nor the normality assumption. We show that our proposal leads to globally and locally efficient estimators of the inner envelope spaces. We a…
A new class of copulas, termed the MGL copula class, is introduced. The new copula originates from extracting the dependence function of the multivariate generalized log-Moyal-gamma distribution whose marginals follow the univariate generalized log-Moyal-gamma (GLMGA) distribution as introduced in \citet{li2019jan}. The MGL copula can capture nonelliptical, exchangeable, and asymmetric dependencies among marginal coordinates and provides a simple formulation for regression applications. We discuss the probabilistic characteristics of MGL copula and obtain the corresponding extreme-value copula…
In many practices, scientists are particularly interested in detecting which of the predictors are truly associated with a multivariate response. It is more accurate to model multiple responses as one vector rather than separating each component one by one. This is particularly true for complex traits having multiple correlated components. A Bayesian multivariate variable selection (BMVS) approach is proposed to select important predictors influencing the multivariate response from a candidate pool with an ultrahigh dimension. By applying the sample-size-dependent spike and slab priors, the BM…
This paper describes a method for a model-based analysis of clinical safety data called multivariate Bayesian logistic regression (MBLR). Parallel logistic regression models are fit to a set of medically related issues, or response variables, and MBLR allows information from the different issues to "borrow strength" from each other. The method is especially suited to sparse response data, as often occurs when fine-grained adverse events are collected from subjects in studies sized more for efficacy than for safety investigations. A combined analysis of data from multiple studies can be perform…
In the field of materials science and engineering, statistical analysis and machine learning techniques have recently been used to predict multiple material properties from an experimental design. These material properties correspond to response variables in the multivariate regression model. This study conducts a penalized maximum likelihood procedure to estimate model parameters, including the regression coefficients and covariance matrix of response variables. In particular, we employ $l_1$-regularization to achieve a sparse estimation of regression coefficients and the inverse covariance m…
We develop Bayesian models for density regression with emphasis on discrete outcomes. The problem of density regression is approached by considering methods for multivariate density estimation of mixed scale variables, and obtaining conditional densities from the multivariate ones. The approach to multivariate mixed scale outcome density estimation that we describe represents discrete variables, either responses or covariates, as discretised versions of continuous latent variables. We present and compare several models for obtaining these thresholds in the challenging context of count data ana…
We present a multivariate Gaussian process regression approach for parameter field reconstruction based on the field's measurements collected at two different scales, the coarse and fine scales. The proposed approach treats the parameter field defined at fine and coarse scales as a bivariate Gaussian process with a parameterized multiscale covariance model. We employ a full bivariate Matérn kernel as multiscale covariance model, with shape and smoothness hyperparameters that account for the coarsening relation between fine and coarse fields. In contrast to similar multiscale kriging approaches…
Quantile regression permits describing how quantiles of a scalar response variable depend on a set of predictors. Because a unique definition of multivariate quantiles is lacking, extending quantile regression to multivariate responses is somewhat complicated. In this paper, we describe a simple approach based on a two-step procedure: in the first step, quantile regression is applied to each response separately; in the second step, the joint distribution of the signs of the residuals is modeled through multinomial regression. The described approach does not require a multidimensional definitio…
In genetic studies, not only can the number of predictors obtained from microarray measurements be extremely large, there can also be multiple response variables. Motivated by such a situation, we consider semiparametric dimension reduction methods in sparse multivariate regression models. Previous studies on joint variable and rank selection have focused on parametric models while here we consider the more challenging varying-coefficient models which make the investigation on nonlinear interactions of variables possible. Spline approximation, rank constraints and concave group penalties are u…
In this article, we consider a non-parametric Bayesian approach to multivariate quantile regression. The collection of related conditional distributions of a response vector Y given a univariate covariate X is modeled using a Dependent Dirichlet Process (DDP) prior. The DDP is used to introduce dependence across x. As the realizations from a Dirichlet process prior are almost surely discrete, we need to convolve it with a kernel. To model the error distribution as flexibly as possible, we use a countable mixture of multidimensional normal distributions as our kernel. For posterior computations…
We consider the multivariate response regression problem with a regression coefficient matrix of low, unknown rank. In this setting, we analyze a new criterion for selecting the optimal reduced rank. This criterion differs notably from the one proposed in Bunea, She and Wegkamp [7] in that it does not require estimation of the unknown variance of the noise, nor depends on a delicate choice of a tuning parameter. We develop an iterative, fully data-driven procedure, that adapts to the optimal signal to noise ratio. This procedure finds the true rank in a few steps with overwhelming probability.…
In the multivariate regression, also referred to as multi-task learning in machine learning, the goal is to recover a vector-valued function based on noisy observations. The vector-valued function is often assumed to be of low rank. Although the multivariate linear regression is extensively studied in the literature, a theoretical study on the multivariate nonlinear regression is lacking. In this paper, we study reduced rank multivariate kernel ridge regression, proposed by \cite{mukherjee2011reduced}. We prove the consistency of the function predictor and provide the convergence rate. An algo…
This paper proposes a new method and algorithm for predicting multivariate responses in a regression setting. Research into classification of High Dimension Low Sample Size (HDLSS) data, in particular microarray data, has made considerable advances, but regression prediction for high-dimensional data with continuous responses has had less attention. Recently Bair et al (2006) proposed an efficient prediction method based on supervised principal component regression (PCR). Motivated by the fact that a larger number of principal components results in better regression performance, this paper ext…
Motivated by recent data analyses in biomedical imaging studies, we consider a class of image-on-scalar regression models for imaging responses and scalar predictors. We propose using flexible multivariate splines over triangulations to handle the irregular domain of the objects of interest on the images, as well as other characteristics of images. The proposed estimators of the coefficient functions are proved to be root-n consistent and asymptotically normal under some regularity conditions. We also provide a consistent and computationally efficient estimator of the covariance function. Asym…
The multivariate linear regression model is an important tool for investigating relationships between several response variables and several predictor variables. The primary interest is in inference about the unknown regression coefficient matrix. We propose multivariate bootstrap techniques as a means for making inferences about the unknown regression coefficient matrix. These bootstrapping techniques are extensions of those developed in Freedman (1981), which are only appropriate for univariate responses. Extensions to the multivariate linear regression model are made without proof. We forma…
Research on Poisson regression analysis for dependent data has been developed rapidly in the last decade. One of difficult problems in a multivariate case is how to construct a cross-correlation structure and at the meantime make sure that the covariance matrix is positive definite. To address the issue, we propose to use convolved Gaussian process (CGP) in this paper. The approach provides a semi-parametric model and offers a natural framework for modeling common mean structure and covariance structure simultaneously. The CGP enables the model to define different covariance structure for each…
