Functional data analysis is a fast evolving branch of statistics. Estimation procedures for the popular functional linear model either suffer from lack of robustness or are computationally burdensome. To address these shortcomings, a flexible family of penalized lower-rank estimators based on a bounded loss function is proposed. The proposed class of estimators is shown to be consistent and can attain high rates of convergence with respect to prediction error under weak regularity conditions. These results can be generalized to higher dimensions under similar assumptions. The finite-sample performance of the proposed family of estimators is investigated by a Monte-Carlo study which shows that these estimators reach high efficiency while offering protection against outliers. The proposed estimators compare favorably to existing approaches robust as well as non-robust alternatives. The good performance of the method is also illustrated on a complex real dataset.
We consider a heteroscedastic regression model in which some of the regression coefficients are zero but it is not known which ones. Penalized quantile regression is a useful approach for analyzing such data. By allowing different covariates to be relevant for modeling conditional quantile functions at different quantile levels, it provides a more complete picture of the conditional distribution of a response variable than mean regression. Existing work on penalized quantile regression has been mostly focused on point estimation. Although bootstrap procedures have recently been shown to be eff…
Skew normal mixture models provide a more flexible framework than the popular normal mixtures for modelling heterogeneous data with asymmetric behaviors. Due to the unboundedness of likelihood function and the divergency of shape parameters, the maximum likelihood estimators of the parameters of interest are often not well defined, leading to dissatisfactory inferential process. We put forward a proposal to deal with these issues simultaneously in the context of penalizing the likelihood function. The resulting penalized maximum likelihood estimator is proved to be strongly consistent when the…
The von Mises-Fisher distribution is one of the most widely used probability distributions to describe directional data. Finite mixtures of von Mises-Fisher distributions have found numerous applications. However, the likelihood function for the finite mixture of von Mises-Fisher distributions is unbounded and consequently the maximum likelihood estimation is not well defined. To address the problem of likelihood degeneracy, we consider a penalized maximum likelihood approach whereby a penalty function is incorporated. We prove strong consistency of the resulting estimator. An Expectation-Maxi…
The popularity of penalized regression in high-dimensional data analysis has led to a demand for new inferential tools for these models. False discovery rate control is widely used in high-dimensional hypothesis testing, but has only recently been considered in the context of penalized regression. Almost all of this work, however, has focused on lasso-penalized linear regression. In this paper, we derive a general method for controlling the marginal false discovery rate that can be applied to any penalized likelihood-based model, such as logistic regression and Cox regression. Our approach is …
Discriminant analysis is a useful classification method. Variable selection for discriminant analysis is becoming more and more im- portant in a high-dimensional setting. This paper is concerned with the binary-class problems of main and interaction effects selection for the quadratic discriminant analysis. We propose a new penalized quadratic discriminant analysis (QDA) for variable selection in binary classification. Under sparsity assumption on the relevant variables, we conduct a penalized liner regression to derive sparse QDA by plug- ging the main and interaction effects in the model. Th…
We propose a new class of nonconvex penalty functions, based on data depth functions, for multitask sparse penalized regression. These penalties quantify the relative position of rows of the coefficient matrix from a fixed distribution centered at the origin. We derive the theoretical properties of an approximate one-step sparse estimator of the coefficient matrix using local linear approximation of the penalty function, and provide algorithm for its computation. For orthogonal design and independent responses, the resulting thresholding rule enjoys near-minimax optimal risk performance, simil…
In this paper, for Lasso penalized linear regression models in high-dimensional settings, we propose a modified cross-validation method for selecting the penalty parameter. The methodology is extended to other penalties, such as Elastic Net. We conduct extensive simulation studies and real data analysis to compare the performance of the modified cross-validation method with other methods. It is shown that the popular $K$-fold cross-validation method includes many noise variables in the selected model, while the modified cross-validation works well in a wide range of coefficient and correlation…
This article considers a linear model in a high dimensional data scenario. We propose a process which uses multiple loss functions both to select relevant predictors and to estimate parameters, and study its asymptotic properties. Variable selection is conducted by a procedure called "vote", which aggregates results from penalized loss functions. Using multiple objective functions separately simplifies algorithms and allows parallel computing, which is convenient and fast. As a special example we consider a quantile regression model, which optimally combines multiple quantile levels. We show t…
Penalized spline regression is a popular method for scatterplot smoothing, but there has long been a debate on how to construct confidence intervals for penalized spline fits. Due to the penalty, the fitted smooth curve is a biased estimate of the target function. Many methods, including Bayesian intervals and the simple-shift bias-reduction, have been proposed to upgrade the coverage of the confidence intervals, but these methods usually fail to adequately improve the situation at predictor values where the function is sharply curved. In this paper, we develop a novel approach to improving th…
The subject of tail estimation for randomly censored data from a heavy tailed distribution receives growing attention, motivated by applications for instance in actuarial statistics. The bias of the available estimators of the extreme value index can be substantial and depends strongly on the amount of censoring. We review the available estimators, propose a new bias reduced estimator, and show how shrinkage estimation can help to keep the MSE under control. A bootstrap algorithm is proposed to construct confidence intervals. We compare these new proposals with the existing estimators through …
We present a new method for post-selection inference for L1 (lasso)-penalized likelihood models, including generalized regression models. Our approach generalizes the post-selection framework presented in Lee et al (2014). The method provides p-values and confidence intervals that are asymptotically valid, conditional on the inherent selection done by the lasso. We present applications of this work to (regularized) logistic regression, Cox's proportional hazards model and the graphical lasso.
Maximum likelihood estimation in logistic regression with mixed effects is known to often result in estimates on the boundary of the parameter space. Such estimates, which include infinite values for fixed effects and singular or infinite variance components, can cause havoc to numerical estimation procedures and inference. We introduce an appropriately scaled additive penalty to the log-likelihood function, or an approximation thereof, which penalizes the fixed effects by the Jeffreys' invariant prior for the model with no random effects and the variance components by a composition of negativ…
Penalized quantile regression (QR) is widely used for studying the relationship between a response variable and a set of predictors under data heterogeneity in high-dimensional settings. Compared to penalized least squares, scalable algorithms for fitting penalized QR are lacking due to the non-differentiable piecewise linear loss function. To overcome the lack of smoothness, a recently proposed convolution-type smoothed method brings an interesting tradeoff between statistical accuracy and computational efficiency for both standard and penalized quantile regressions. In this paper, we propose…
Analyzing multi-layered graphical models provides insight into understanding the conditional relationships among nodes within layers after adjusting for and quantifying the effects of nodes from other layers. We obtain the penalized maximum likelihood estimator for Gaussian multi-layered graphical models, based on a computational approach involving screening of variables, iterative estimation of the directed edges between layers and undirected edges within layers and a final refitting and stability selection step that provides improved performance in finite sample settings. We establish the co…
We consider both $\ell _{0}$-penalized and $\ell _{0}$-constrained quantile regression estimators. For the $\ell _{0}$-penalized estimator, we derive an exponential inequality on the tail probability of excess quantile prediction risk and apply it to obtain non-asymptotic upper bounds on the mean-square parameter and regression function estimation errors. We also derive analogous results for the $\ell _{0}$-constrained estimator. The resulting rates of convergence are nearly minimax-optimal and the same as those for $\ell _{1}$-penalized and non-convex penalized estimators. Further, we charact…
Quantile regression predicts the $τ$-quantile of the conditional distribution of a response variable given the explanatory variable for $τ\in(0,1)$. The aim of this paper is to establish the asymptotic distribution of the quantile estimator obtained by penalized spline method. A simulation and an exploration of real data are performed to validate our results.
This paper is concerned with asymptotic theory for penalized spline estimator in bivariate additive model. The focus of this paper is put upon the penalized spline estimator obtained by the backfitting algorithm. The convergence of the algorithm as well as the uniqueness of its solution are shown. The asymptotic bias and variance of penalized spline estimator are derived by an efficient use of the asymptotic results for the penalized spline estimator in marginal univariate model. Asymptotic normality of estimator is also developed, by which an approximate confidence interval can be obtained. S…
Confidence intervals based on penalized maximum likelihood estimators such as the LASSO, adaptive LASSO, and hard-thresholding are analyzed. In the known-variance case, the finite-sample coverage properties of such intervals are determined and it is shown that symmetric intervals are the shortest. The length of the shortest intervals based on the hard-thresholding estimator is larger than the length of the shortest interval based on the adaptive LASSO, which is larger than the length of the shortest interval based on the LASSO, which in turn is larger than the standard interval based on the ma…
This work studies the statistical properties of the maximum penalized likelihood approach in a semi-parametric framework. We recall the penalized likelihood approach for estimating a function and review some asymptotic results. We investigate the properties of two estimators of the variance of maximum penalized likelihood estimators: sandwich estimator and a Bayesian estimator. The coverage rates of confidence intervals based on these estimators are studied through a simulation study of survival data. In a first simulation the coverage rates for the survival function and the hazard function ar…
We study the distributions of the LASSO, SCAD, and thresholding estimators, in finite samples and in the large-sample limit. The asymptotic distributions are derived for both the case where the estimators are tuned to perform consistent model selection and for the case where the estimators are tuned to perform conservative model selection. Our findings complement those of Knight and Fu (2000) and Fan and Li (2001). We show that the distributions are typically highly nonnormal regardless of how the estimator is tuned, and that this property persists in large samples. The uniform convergence rat…
$\ell_1$-penalized Multinomial Regression: Estimation, inference, and prediction, with an application to risk factor identification for different dementia subtypes
We study the asymptotic properties of the SCAD-penalized least squares estimator in sparse, high-dimensional, linear regression models when the number of covariates may increase with the sample size. We are particularly interested in the use of this estimator for simultaneous variable selection and estimation. We show that under appropriate conditions, the SCAD-penalized least squares estimator is consistent for variable selection and that the estimators of nonzero coefficients have the same asymptotic distribution as they would have if the zero coefficients were known in advance. Simulation s…
This paper studies the non-asymptotic merits of the double $\ell_1$-regularized for heterogeneous overdispersed count data via negative binomial regressions. Under the restricted eigenvalue conditions, we prove the oracle inequalities for Lasso estimators of two partial regression coefficients for the first time, using concentration inequalities of empirical processes. Furthermore, derived from the oracle inequalities, the consistency and convergence rate for the estimators are the theoretical guarantees for further statistical inference. Finally, both simulations and a real data analysis demo…
In this paper, we propose a one-pass algorithm on MapReduce for penalized linear regression \[f_λ(α, β) = \|Y - α\mathbf{1} - Xβ\|_2^2 + p_λ(β)\] where $α$ is the intercept which can be omitted depending on application; $β$ is the coefficients and $p_λ$ is the penalized function with penalizing parameter $λ$. $f_λ(α, β)$ includes interesting classes such as Lasso, Ridge regression and Elastic-net. Compared to latest iterative distributed algorithms requiring multiple MapReduce jobs, our algorithm achieves huge performance improvement; moreover, our algorithm is exact compared to the approximat…
This paper develops a general theory on rates of convergence of penalized spline estimators for function estimation when the likelihood functional is concave in candidate functions, where the likelihood is interpreted in a broad sense that includes conditional likelihood, quasi-likelihood, and pseudo-likelihood. The theory allows all feasible combinations of the spline degree, the penalty order, and the smoothness of the unknown functions. According to this theory, the asymptotic behaviors of the penalized spline estimators depends on interplay between the spline knot number and the penalty pa…
The RNA-sequencing (RNA-seq) is becoming increasingly popular for quantifying gene expression levels. Since the RNA-seq measurements are relative in nature, between-sample normalization of counts is an essential step in differential expression (DE) analysis. The normalization of existing DE detection algorithms is ad hoc and performed once for all prior to DE detection, which may be suboptimal since ideally normalization should be based on non-DE genes only and thus coupled with DE detection. We propose a unified statistical model for joint normalization and DE detection of log-transformed RNA…
We propose an algorithm, semismooth Newton coordinate descent (SNCD), for the elastic-net penalized Huber loss regression and quantile regression in high dimensional settings. Unlike existing coordinate descent type algorithms, the SNCD updates each regression coefficient and its corresponding subgradient simultaneously in each iteration. It combines the strengths of the coordinate descent and the semismooth Newton algorithm, and effectively solves the computational challenges posed by dimensionality and nonsmoothness. We establish the convergence properties of the algorithm. In addition, we p…
We propose a new method, semi-penalized inference with direct false discovery rate control (SPIDR), for variable selection and confidence interval construction in high-dimensional linear regression. SPIDR first uses a semi-penalized approach to constructing estimators of the regression coefficients. We show that the SPIDR estimator is ideal in the sense that it equals an ideal least squares estimator with high probability under a sparsity and other suitable conditions. Consequently, the SPIDR estimator is asymptotically normal. Based on this distributional result, SPIDR determines the selectio…
In this paper, we propose a new semiparametric regression estimator by using a hybrid technique of a parametric approach and a nonparametric penalized spline method. The overall shape of the true regression function is captured by the parametric part, while its residual is consistently estimated by the nonparametric part. Asymptotic theory for the proposed semiparametric estimator is developed, showing that its behavior is dependent on the asymptotics for the nonparametric penalized spline estimator as well as on the discrepancy between the true regression function and the parametric part. As …
This paper discusses asymptotic theory for penalized spline estimators in generalized additive models. The purpose of this paper is to establish the asymptotic bias and variance as well as the asymptotic normality of the penalized spline estimators proposed by Marx and Eilers (1998). Furthermore, the asymptotics for the penalized quasi likelihood fit in mixed models are also discussed.
We introduce a covariate-specific total variation penalty in two semiparametric models for the rate function of recurrent event process. The two models are a stratified Cox model, introduced in Prentice et al. (1981), and a stratified Aalen's additive model. We show the consistency and asymptotic normality of our penalized estimators. We demonstrate, through a simulation study, that our estimators outperform classical estimators for small to moderate sample sizes. Finally an application to the bladder tumour data of Byar (1980) is presented.
The authors consider the problem of estimating the density $g$ of independent and identically distributed variables $X\_i$, from a sample $Z\_1, ..., Z\_n$ where $Z\_i=X\_i+σε\_i$, $i=1, ..., n$, $ε$ is a noise independent of $X$, with $σε$ having known distribution. They present a model selection procedure allowing to construct an adaptive estimator of $g$ and to find non-asymptotic bounds for its $\mathbb{L}\_2(\mathbb{R})$-risk. The estimator achieves the minimax rate of convergence, in most cases where lowers bounds are available. A simulation study gives an illustration of the good practi…
Since its early use in least squares regression problems, the l1-penalization framework for variable selection has been employed in conjunction with a wide range of loss functions encompassing regression, classification and survival analysis. While a well developed theory exists for the l1-penalized least squares estimates, few results concern the behavior of l1-penalized estimates for general loss functions. In this paper, we derive two results concerning penalized estimates for a wide array of penalty and loss functions. Our first result characterizes the asymptotic distribution of penalized…
The Graduate University for Advanced Science (SOKENDAI)(综合研究大学院大学(SOKENDAI))
We propose an estimator of prediction error using an approximate message passing (AMP) algorithm that can be applied to a broad range of sparse penalties. Following Stein's lemma, the estimator of the generalized degrees of freedom, which is a key quantity for the construction of the estimator of the prediction error, is calculated at the AMP fixed point. The resulting form of the AMP-based estimator does not depend on the penalty function, and its value can be further improved by considering the correlation between predictors. The proposed estimator is asymptotically unbiased when the compone…
We consider partly linear transformation models applied to current status data. The unknown quantities are the transformation function, a linear regression parameter and a nonparametric regression effect. It is shown that the penalized MLE for the regression parameter is asymptotically normal and efficient and converges at the parametric rate, although the penalized MLE for the transformation function and nonparametric regression effect are only $n^{1/3}$ consistent. Inference for the regression parameter based on a block jackknife is investigated. We also study computational issues and demons…
Many statistical estimation procedures lead to nonconvex optimization problems. Algorithms to solve these are often guaranteed to output a stationary point of the optimization problem. Oracle inequalities are an important theoretical instrument to asses the statistical performance of an estimator. Oracle results have focused on the theoretical properties of the uncomputable (global) minimum or maximum. In the present work a general framework used for convex optimization problems to derive oracle inequalities for stationary points is extended. A main new ingredient of these oracle inequalities …
In finite mixtures of location-scale distributions, if there is no constraint or penalty on the parameters, then the maximum likelihood estimator does not exist because the likelihood is unbounded. To avoid this problem, we consider a penalized likelihood, where the penalty is a function of the minimum of the ratios of the scale parameters and the sample size. It is shown that the penalized maximum likelihood estimator is strongly consistent. We also analyze the consistency of a penalized maximum likelihood estimator where the penalty is imposed on the scale parameters themselves.
We derive asymptotic properties of penalized estimators for singular models for which identifiability may break and the true parameter values can lie on the boundary of the parameter space. Selection consistency of the estimators is also validated. The problem that the true values lie on the boundary is dealt with by our previous results that are applicable to singular models, besides, penalized estimation and non-ergodic statistics. In order to overcome non-identifiability, we consider a suitable penalty such as the non-convex Bridge and the adaptive Lasso that stabilizes the asymptotic behav…
We study the convergence properties, in Hellinger and related distances, of nonparametric density estimators based on measure transport. These estimators represent the measure of interest as the pushforward of a chosen reference distribution under a transport map, where the map is chosen via a maximum likelihood objective (equivalently, minimizing an empirical Kullback-Leibler loss) or a penalized version thereof. We establish concentration inequalities for a general class of penalized measure transport estimators, by combining techniques from M-estimation with analytical properties of the tra…
Inference based on the penalized density ratio model is proposed and studied. The model under consideration is specified by assuming that the log--likelihood function of two unknown densities is of some parametric form. The model has been extended to cover multiple samples problems while its theoretical properties have been investigated using large sample theory. A main application of the density ratio model is testing whether two, or more, distributions are equal. We extend these results by arguing that the penalized maximum empirical likelihood estimator has less mean square error than that …
We consider a one-dimensional diffusion process $(X_t)$ which is observed at $n+1$ discrete times with regular sampling interval $Δ$. Assuming that $(X_t)$ is strictly stationary, we propose nonparametric estimators of the drift and diffusion coefficients obtained by a penalized least squares approach. Our estimators belong to a finite-dimensional function space whose dimension is selected by a data-driven method. We provide non-asymptotic risk bounds for the estimators. When the sampling interval tends to zero while the number of observations and the length of the observation time interval te…
Penalized regression estimators are a popular tool for the analysis of sparse and high-dimensional data sets. However, penalized regression estimators defined using an unbounded loss function can be very sensitive to the presence of outlying observations, especially high leverage outliers. Moreover, it can be particularly challenging to detect outliers in high-dimensional data sets. Thus, robust estimators for sparse and high-dimensional linear regression models are in need. In this paper, we study the robust and asymptotic properties of MM-Bridge and adaptive MM-Bridge estimators: $\ell_q$-pe…
It has been shown that AIC-type criteria are asymptotically efficient selectors of the tuning parameter in non-concave penalized regression methods under the assumption that the population variance is known or that a consistent estimator is available. We relax this assumption to prove that AIC itself is asymptotically efficient and we study its performance in finite samples. In classical regression, it is known that AIC tends to select overly complex models when the dimension of the maximum candidate model is large relative to the sample size. Simulation studies suggest that AIC suffers from t…
We consider the problem of learning a coefficient vector $x_{0}$ in $R^{N}$ from noisy linear observations $y=Fx_{0}+w$ in $R^{M}$ in the high dimensional limit $M,N$ to infinity with $α=M/N$ fixed. We provide a rigorous derivation of an explicit formula -- first conjectured using heuristic methods from statistical physics -- for the asymptotic mean squared error obtained by penalized convex regression estimators such as the LASSO or the elastic net, for a class of very generic random matrices corresponding to rotationally invariant data matrices with arbitrary spectrum. The proof is based on …
In this paper, we discuss a family of robust, high-dimensional regression models for quantile and composite quantile regression, both with and without an adaptive lasso penalty for variable selection. We reformulate these quantile regression problems and obtain estimators by applying the alternating direction method of multipliers (ADMM), majorize-minimization (MM), and coordinate descent (CD) algorithms. Our new approaches address the lack of publicly available methods for (composite) quantile regression, especially for high-dimensional data, both with and without regularization. Through simu…
We consider a dynamical system with small noise for which the drift is parametrized by a finite dimensional parameter. For this model we consider minimum distance estimation from continuous time observations under $l^p$-penalty imposed on the parameters in the spirit of the Lasso approach with the aim of simultaneous estimation and model selection. We study the consistency and the asymptotic distribution of these Lasso-type estimators for different values of $p$. For $p=1$ we also consider the adaptive version of the Lasso estimator and establish its oracle properties.
Whereas translating the coding of predictor variables does not change the fit of a polynomial least squares regression, penalized polynomial regressions are potentially affected. A result on which terms can be penalized to maintain the invariance to translations of the coding has earlier been published. A generalization of a corresponding proposition, which requires a more precise mathematical framework, is presented in this short note.