We propose a novel approach for automatic extraction (instance segmentation) of fibers from low resolution 3D X-ray computed tomography scans of short glass fiber reinforced polymers. We have designed a 3D instance segmentation architecture built upon a deep fully convolutional network for semantic segmentation with an extra output for embedding learning. We show that the embedding learning is capable of learning a mapping of voxels to an embedded space in which a standard clustering algorithm can be used to distinguish between different instances of an object in a volume. In addition, we discuss a merging post-processing method which makes it possible to process volumes of any size. The proposed 3D instance segmentation network together with our merging algorithm is the first known to authors knowledge procedure that produces results good enough, that they can be used for further analysis of low resolution fiber composites CT scans.
Volume Graphics GmbH(Volume Graphics有限公司);University Medical Center Mannheim, Heidelberg University(海德堡大学曼海姆大学医学中心);Heidelberg University(海德堡大学);University of Padova(帕多瓦大学)
We present the first attempt to perform short glass fiber semantic segmentation from X-ray computed tomography volumetric datasets at medium (3.9 μm isotropic) and low (8.3 μm isotropic) resolution using deep learning architectures. We performed experiments on both synthetic and real CT scans and evaluated deep fully convolutional architectures with both 2D and 3D kernels. Our artificial neural networks outperform existing methods at both medium and low resolution scans.
University of British Columbia(不列颠哥伦比亚大学);University of Nottingham(诺丁汉大学);Weill Cornell Medicine-Qatar(威尔康奈尔医学院卡塔尔分院)
Semantic image segmentation is one of the most important tasks in medical image analysis. Most state-of-the-art deep learning methods require a large number of accurately annotated examples for model training. However, accurate annotation is difficult to obtain especially in medical applications. In this paper, we propose a spatially constrained deep convolutional neural network (DCNN) to achieve smooth and robust image segmentation using inaccurately annotated labels for training. In our proposed method, image segmentation is formulated as a graph optimization problem that is solved by a DCNN…
National Institutes of Health Clinical Center(美国国立卫生研究院临床中心)
This paper reports Deep LOGISMOS approach to 3D tumor segmentation by incorporating boundary information derived from deep contextual learning to LOGISMOS - layered optimal graph image segmentation of multiple objects and surfaces. Accurate and reliable tumor segmentation is essential to tumor growth analysis and treatment selection. A fully convolutional network (FCN), UNet, is first trained using three adjacent 2D patches centered at the tumor, providing contextual UNet segmentation and probability map for each 2D patch. The UNet segmentation is then refined by Gaussian Mixture Model (GMM) a…
In depth-sensing applications ranging from home robotics to AR/VR, it will be common to acquire 3D scans of interior spaces repeatedly at sparse time intervals (e.g., as part of regular daily use). We propose an algorithm that analyzes these "rescans" to infer a temporal model of a scene with semantic instance information. Our algorithm operates inductively by using the temporal model resulting from past observations to infer an instance segmentation of a new scan, which is then used to update the temporal model. The model contains object instance associations across time and thus can be used …
Stanford University(斯坦福大学);Brown University(布朗大学);Google(谷歌);DeepMind(深度思维);Technical University of Munich(慕尼黑工业大学)
We introduce ScanComplete, a novel data-driven approach for taking an incomplete 3D scan of a scene as input and predicting a complete 3D model along with per-voxel semantic labels. The key contribution of our method is its ability to handle large scenes with varying spatial extent, managing the cubic growth in data size as scene size increases. To this end, we devise a fully-convolutional generative 3D CNN model whose filter kernels are invariant to the overall scene size. The model can be trained on scene subvolumes but deployed on arbitrarily large scenes at test time. In addition, we propo…
Mandible bone segmentation from computed tomography (CT) scans is challenging due to mandible's structural irregularities, complex shape patterns, and lack of contrast in joints. Furthermore, connections of teeth to mandible and mandible to remaining parts of the skull make it extremely difficult to identify mandible boundary automatically. This study addresses these challenges by proposing a novel framework where we define the segmentation as two complementary tasks: recognition and delineation. For recognition, we use random forest regression to localize mandible in 3D. For delineation, we p…
We introduce 3D-SIS, a novel neural network architecture for 3D semantic instance segmentation in commodity RGB-D scans. The core idea of our method is to jointly learn from both geometric and color signal, thus enabling accurate instance predictions. Rather than operate solely on 2D frames, we observe that most computer vision applications have multi-view RGB-D input available, which we leverage to construct an approach for 3D instance segmentation that effectively fuses together these multi-modal inputs. Our network leverages high-resolution RGB input by associating 2D images with the volume…
Yes, it can. Data augmentation is perhaps the oldest preprocessing step in computer vision literature. Almost every computer vision model trained on imaging data uses some form of augmentation. In this paper, we use the inter-vertebral disk segmentation task alongside a deep residual U-Net as the learning model, to explore the effectiveness of augmentation. In the extreme, we observed that a model trained on patches extracted from just one scan, with each patch augmented 50 times; achieved a Dice score of 0.73 in a validation set of 40 cases. Qualitative evaluation indicated a clinically usabl…
Thanks to the capacity for long-range dependencies and robustness to irregular shapes, vision transformers and deformable convolutions are emerging as powerful vision techniques of segmentation.Meanwhile, Graph Convolution Networks (GCN) optimize local features based on global topological relationship modeling. Particularly, they have been proved to be effective in addressing issues in medical imaging segmentation tasks including multi-domain generalization for low-quality images. In this paper, we present a novel, effective, and robust framework for medical image segmentation, namely, UGforme…
Point2Tree(P2T) -- framework for parameter tuning of semantic and instance segmentation used with mobile laser scanning data in coniferous forest
Norwegian Institute for Bioeconomy Research (NIBIO)(挪威生物经济研究所(NIBIO));University College London(伦敦大学学院);NERC National Centre for Earth Observation(NERC国家地球观测中心)
University of Pittsburgh(匹兹堡大学);Carnegie Mellon University(卡内基梅隆大学);The University of Melbourne(墨尔本大学)
An organ segmentation method that can generalize to unseen contrasts and scanner settings can significantly reduce the need for retraining of deep learning models. Domain Generalization (DG) aims to achieve this goal. However, most DG methods for segmentation require training data from multiple domains during training. We propose a novel adversarial domain generalization method for organ segmentation trained on data from a \emph{single} domain. We synthesize the new domains via learning an adversarial domain synthesizer (ADS) and presume that the synthetic domains cover a large enough area of …
A wide range of techniques can be considered for segmentation of images of nanostructured surfaces. Manually segmenting these images is time-consuming and results in a user-dependent segmentation bias, while there is currently no consensus on the best automated segmentation methods for particular techniques, image classes, and samples. Any image segmentation approach must minimise the noise in the images to ensure accurate and meaningful statistical analysis can be carried out. Here we develop protocols for the segmentation of images of 2D assemblies of gold nanoparticles formed on silicon sur…
UD-Mamba: A pixel-level uncertainty-driven Mamba model for medical image segmentation
University of California, Santa Cruz(加州大学圣克鲁兹分校);Johns Hopkins University(约翰霍普金斯大学);Stanford University(斯坦福大学);Mohamed bin Zayed University of Artificial Intelligence(穆罕默德·本·扎耶德人工智能大学);University of Adelaide(阿德莱德大学)
University of Freiburg(弗莱堡大学);Toyota Research Institute(丰田研究院)
Understanding the semantic characteristics of the environment is a key enabler for autonomous robot operation. In this paper, we propose a deep convolutional neural network (DCNN) for the semantic segmentation of a LiDAR scan into the classes car, pedestrian or bicyclist. This architecture is based on dense blocks and efficiently utilizes depth separable convolutions to limit the number of parameters while still maintaining state-of-the-art performance. To make the predictions from the DCNN temporally consistent, we propose a Bayes filter based method. This method uses the predictions from the…
Georgia Institute of Technology(佐治亚理工学院);Telecom Paris(巴黎电信学院);Medicine School of Tunis(突尼斯医学院)
Breast cancer is one of the factors that cause the increase of mortality of women. The most widely used method for diagnosing this geological disease i.e. breast cancer is the ultrasound scan. Several key features such as the smoothness and the texture of the tumor captured through ultrasound scans encode the abnormality of the breast tumors (malignant from benign). However, ultrasound scans are often noisy and include irrelevant parts of the breast that may bias the segmentation of eventual tumors. In this paper, we are going to extract the region of interest ( i.e, bounding boxes of the tumo…
With the increased availability of 3D data, the need for solutions processing those also increased rapidly. However, adding dimension to already reliably accurate 2D approaches leads to immense memory consumption and higher computational complexity. These issues cause current hardware to reach its limitations, with most methods forced to reduce the input resolution drastically. Our main contribution is a novel deep 3D semantic segmentation method for gun detection in baggage CT scans that enables fast training and low video memory consumption for high-resolution voxelized volumes. We introduce…
Chongqing University of Posts and Telecommunications(重庆邮电大学);Stomatological Hospital of Chongqing Medical University(重庆医科大学附属口腔医院);Macau University of Science and Technology(澳门科技大学);Xi’an Jiaotong University(西安交通大学);ShanghaiTech University(上海科技大学);Shanghai United Imaging Intelligence Co., Ltd.(上海联影智能科技有限公司);The University of Hong Kong(香港大学)
Precise segmentation of teeth from intra-oral scanner images is an essential task in computer-aided orthodontic surgical planning. The state-of-the-art deep learning-based methods often simply concatenate the raw geometric attributes (i.e., coordinates and normal vectors) of mesh cells to train a single-stream network for automatic intra-oral scanner image segmentation. However, since different raw attributes reveal completely different geometric information, the naive concatenation of different raw attributes at the (low-level) input stage may bring unnecessary confusion in describing and dif…
Image segmentation plays a pivotal role in several medical-imaging applications by assisting the segmentation of the regions of interest. Deep learning-based approaches have been widely adopted for semantic segmentation of medical data. In recent years, in addition to 2D deep learning architectures, 3D architectures have been employed as the predictive algorithms for 3D medical image data. In this paper, we propose a 3D stack-based deep learning technique for segmenting manifestations of consolidation and ground-glass opacities in 3D Computed Tomography (CT) scans. We also present a comparison…
UC San Diego(加州大学圣地亚哥分校);General Electric Global Research(通用电气全球研究中心)
Ultrasound scanning is essential in several medical diagnostic and therapeutic applications. It is used to visualize and analyze anatomical features and structures that influence treatment plans. However, it is both labor intensive, and its effectiveness is operator dependent. Real-time accurate and robust automatic detection and tracking of anatomical structures while scanning would significantly impact diagnostic and therapeutic procedures to be consistent and efficient. In this paper, we propose a deep learning framework to automatically detect and track a specific anatomical target structu…
Indian Institute of Technology Jodhpur(印度理工学院焦特布尔分校);Indian Institute of Technology Mandi(印度理工学院曼迪分校)
In this paper, we propose a novel deep learning architecture combining stacked Bi-directional LSTM and LSTMs with the Siamese network architecture for segmentation of brain fibers, obtained from tractography data, into anatomically meaningful clusters. The proposed network learns the structural difference between fibers of different classes, which enables it to classify fibers with high accuracy. Importantly, capturing such deep inter and intra class structural relationship also ensures that the segmentation is robust to relative rotation among test and training data, hence can be used with un…
Segmentation of mandibles in CT scans during virtual surgical planning is crucial for 3D surgical planning in order to obtain a detailed surface representation of the patients bone. Automatic segmentation of mandibles in CT scans is a challenging task due to large variation in their shape and size between individuals. In order to address this challenge we propose a convolutional neural network approach for mandible segmentation in CT scans by considering the continuum of anatomical structures through different planes. The proposed convolutional neural network adopts the architecture of the U-N…
Indian Institute of Technology, Mandi(印度理工学院曼迪分校);Indian Institute of Technology, Jodhpur(印度理工学院焦特布尔分校)
The segregation of brain fiber tractography data into distinct and anatomically meaningful clusters can help to comprehend the complex brain structure and early investigation and management of various neural disorders. We propose a novel stacked bidirectional long short-term memory(LSTM) based segmentation network, (BrainSegNet) for human brain fiber tractography data classification. We perform a two-level hierarchical classification a) White vs Grey matter (Macro) and b) White matter clusters (Micro). BrainSegNet is trained over three brain tractography data having over 250,000 fibers each. O…
Heidelberg University(海德堡大学);University Medical Center Mannheim(曼海姆大学医学中心);Interdisciplinary Center for Scientific Computing (IWR)(跨学科科学计算中心(IWR));Volume Graphics GmbH(Volume Graphics有限公司);University of Padova(帕多瓦大学)
Comparing different algorithms for segmenting glass fibers in industrial computed tomography (CT) scans is difficult due to the absence of a standard reference dataset. In this work, we introduce a set of annotated scans of short-fiber reinforced polymers (SFRP) as well as synthetically created CT volume data together with the evaluation metrics. We suggest both the metrics and this data set as a reference for studying the performance of different algorithms. The real scans were acquired by a Nikon MCT225 X-ray CT system. The simulated scans were created by the use of an in-house computational…
University of North Carolina at Charlotte(北卡罗来纳大学夏洛特分校);University of Science and Technology Beijing(北京科技大学);Scoop Medical
Brain tumor segmentation plays a pivotal role in medical image processing. In this work, we aim to segment brain MRI volumes. 3D convolution neural networks (CNN) such as 3D U-Net and V-Net employing 3D convolutions to capture the correlation between adjacent slices have achieved impressive segmentation results. However, these 3D CNN architectures come with high computational overheads due to multiple layers of 3D convolutions, which may make these models prohibitive for practical large-scale applications. To this end, we propose a highly efficient 3D CNN to achieve real-time dense volumetric …
Chest X-ray (CXR) is one of the most commonly prescribed medical imaging procedures, often with over 2-10x more scans than other imaging modalities such as MRI, CT scan, and PET scans. These voluminous CXR scans place significant workloads on radiologists and medical practitioners. Organ segmentation is a crucial step to obtain effective computer-aided detection on CXR. In this work, we propose Structure Correcting Adversarial Network (SCAN) to segment lung fields and the heart in CXR images. SCAN incorporates a critic network to impose on the convolutional segmentation network the structural …
Instance segmentation is a problem of significance in computer vision. However, preparing annotated data for this task is extremely time-consuming and costly. By combining the advantages of 3D scanning, reasoning, and GAN-based domain adaptation techniques, we introduce a novel pipeline named SRDA to obtain large quantities of training samples with very minor effort. Our pipeline is well-suited to scenes that can be scanned, i.e. most indoor and some outdoor scenarios. To evaluate our performance, we build three representative scenes and a new dataset, with 3D models of various common objects …
Lesion segmentation in medical imaging serves as an effective tool for assessing tumor sizes and monitoring changes in growth. However, not only is manual lesion segmentation time-consuming, but it is also expensive and requires expert radiologist knowledge. Therefore many hospitals rely on a loose substitute called response evaluation criteria in solid tumors (RECIST). Although these annotations are far from precise, they are widely used throughout hospitals and are found in their picture archiving and communication systems (PACS). Therefore, these annotations have the potential to serve as a…
Biomediq A/S(Biomediq公司);University of Copenhagen(哥本哈根大学)
Scanner drift is a well-known magnetic resonance imaging (MRI) artifact characterized by gradual signal degradation and scan intensity changes over time. In addition, hardware and software updates may imply abrupt changes in signal. The combined effects are particularly challenging for automatic image analysis methods used in longitudinal studies. The implication is increased measurement variation and a risk of bias in the estimations (e.g. in the volume change for a structure). We proposed two quite different approaches for scanner drift normalization and demonstrated the performance for segm…
City University of New York(纽约市立大学);The College of Staten Island(史泰登岛学院);The City College(城市学院);Memorial Sloan-Kettering (MSK) Cancer Center(纪念斯隆-凯特琳癌症中心)
Lung segmentation in computerized tomography (CT) images is an important procedure in various lung disease diagnosis. Most of the current lung segmentation approaches are performed through a series of procedures with manually empirical parameter adjustments in each step. Pursuing an automatic segmentation method with fewer steps, in this paper, we propose a novel deep learning Generative Adversarial Network (GAN) based lung segmentation schema, which we denote as LGAN. Our proposed schema can be generalized to different kinds of neural networks for lung segmentation in CT images and is evaluat…
Quantitative computed tomography (QCT) is a standard method to determine bone mineral density (BMD) in the spine. Traditionally single 8 - 10 mm thick slices have been analyzed only. Current spiral CT scanners provide true 3D acquisition schemes allowing for a more differential BMD analysis and an assessment of geometric parameters, which may improve fracture prediction. We developed a novel 3D segmentation approach that combines deformable balloons, multi seeded volume growing, and dedicated morphological operations to extract the vertebral bodies. An anatomy-oriented coordinate system attach…
Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center(美国国立卫生研究院临床中心放射与成像科学部成像生物标志物和计算机辅助诊断实验室);Ping An Insurance Company of China(中国平安保险(集团)股份有限公司)
Lesion segmentation on computed tomography (CT) scans is an important step for precisely monitoring changes in lesion/tumor growth. This task, however, is very challenging since manual segmentation is prohibitively time-consuming, expensive, and requires professional knowledge. Current practices rely on an imprecise substitute called response evaluation criteria in solid tumors (RECIST). Although these markers lack detailed information about the lesion regions, they are commonly found in hospitals' picture archiving and communication systems (PACS). Thus, these markers have the potential to se…
Technical University of Munich(慕尼黑工业大学);University of California, Irvine(加利福尼亚大学尔湾分校)
The segmentation of liver lesions is crucial for detection, diagnosis and monitoring progression of liver cancer. However, design of accurate automated methods remains challenging due to high noise in CT scans, low contrast between liver and lesions, as well as large lesion variability. We propose a 3D automatic, unsupervised method for liver lesions segmentation using a phase separation approach. It is assumed that liver is a mixture of two phases: healthy liver and lesions, represented by different image intensities polluted by noise. The Cahn-Hilliard equation is used to remove the noise an…
University of Marburg(马尔堡大学);Fraunhofer MEVIS – Institute for Medical Image Computing(弗劳恩霍夫梅维斯医学图像计算研究所)
Diffusion Tensor Imaging (DTI) provides the possibility of estimating the location and course of eloquent structures in the human brain. Knowledge about this is of high importance for preoperative planning of neurosurgical interventions and for intraoperative guidance by neuronavigation in order to minimize postoperative neurological deficits. Therefore, the segmentation of these structures as closed, three-dimensional object is necessary. In this contribution, two methods for fiber bundle segmentation between two defined regions are compared using software phantoms (abstract model and anatomi…
Bilkent University(比尔肯特大学);Koc University School of Medicine(科克大学医学院);Koc University(科克大学)
The Henle's fiber layer (HFL) in the retina carries valuable information on the macular condition of an eye. However, in the common practice, this layer is not separately segmented but rather included in the outer nuclear layer since it is difficult to perceive HFL contours on standard optical coherence tomography (OCT) imaging. Due to its variable reflectivity under an imaging beam, delineating the HFL contours necessitates directional OCT, which requires additional imaging. This paper addresses this issue by introducing a shape-preserving network, FourierNet, that achieves HFL segmentation i…
This paper addresses the task of separating ground points from airborne LiDAR point cloud data in urban areas. A novel ground filtering method using scan line segmentation is proposed here, which we call SLSGF. It utilizes the scan line information in LiDAR data to segment the LiDAR data. The similarity measurements are designed to make it possible to segment complex roof structures into a single segment as much as possible so the topological relationships between the roof and the ground are simpler, which will benefit the labeling process. In the labeling process, the initial ground segments …
In this paper, we introduce a Bayesian deep learning based model for segmenting the photoreceptor layer in pathological OCT scans. Our architecture provides accurate segmentations of the photoreceptor layer and produces pixel-wise epistemic uncertainty maps that highlight potential areas of pathologies or segmentation errors. We empirically evaluated this approach in two sets of pathological OCT scans of patients with age-related macular degeneration, retinal vein oclussion and diabetic macular edema, improving the performance of the baseline U-Net both in terms of the Dice index and the area …
3D tooth segmentation is an important task for digital orthodontics. Several Deep Learning methods have been proposed for automatic tooth segmentation from 3D dental models or intraoral scans. These methods require annotated 3D intraoral scans. Manually annotating 3D intraoral scans is a laborious task. One approach is to devise self-supervision methods to reduce the manual labeling effort. Compared to other types of point cloud data like scene point cloud or shape point cloud data, 3D tooth point cloud data has a very regular structure and a strong shape prior. We look at how much representat…
Segmentation in 3D scans is playing an increasingly important role in current clinical practice supporting diagnosis, tissue quantification, or treatment planning. The current 3D approaches based on convolutional neural networks usually suffer from at least three main issues caused predominantly by implementation constraints - first, they require resizing the volume to the lower-resolutional reference dimensions, second, the capacity of such approaches is very limited due to memory restrictions, and third, all slices of volumes have to be available at any given training or testing time. We add…
Johns Hopkins University(约翰斯·霍普金斯大学);University of California San Diego(加利福尼亚大学圣迭戈分校);Tongji University(同济大学);The Johns Hopkins University School of Medicine(约翰斯·霍普金斯大学医学院)
Tubular structure segmentation in medical images, e.g., segmenting vessels in CT scans, serves as a vital step in the use of computers to aid in screening early stages of related diseases. But automatic tubular structure segmentation in CT scans is a challenging problem, due to issues such as poor contrast, noise and complicated background. A tubular structure usually has a cylinder-like shape which can be well represented by its skeleton and cross-sectional radii (scales). Inspired by this, we propose a geometry-aware tubular structure segmentation method, Deep Distance Transform (DDT), which…
The Johns Hopkins University(约翰斯·霍普金斯大学);The Johns Hopkins University School of Medicine(约翰斯·霍普金斯大学医学院)
Automatic segmentation of an organ and its cystic region is a prerequisite of computer-aided diagnosis. In this paper, we focus on pancreatic cyst segmentation in abdominal CT scan. This task is important and very useful in clinical practice yet challenging due to the low contrast in boundary, the variability in location, shape and the different stages of the pancreatic cancer. Inspired by the high relevance between the location of a pancreas and its cystic region, we introduce extra deep supervision into the segmentation network, so that cyst segmentation can be improved with the help of rela…
The Johns Hopkins University(约翰斯·霍普金斯大学);Shanghai University(上海大学);The Johns Hopkins University School of Medicine(约翰斯·霍普金斯大学医学院)
Deep neural networks have been widely adopted for automatic organ segmentation from abdominal CT scans. However, the segmentation accuracy of some small organs (e.g., the pancreas) is sometimes below satisfaction, arguably because deep networks are easily disrupted by the complex and variable background regions which occupies a large fraction of the input volume. In this paper, we formulate this problem into a fixed-point model which uses a predicted segmentation mask to shrink the input region. This is motivated by the fact that a smaller input region often leads to more accurate segmentation…
Berkeley Institute for Data Science, University of California, Berkeley(加州大学伯克利分校伯克利数据科学研究所);Lawrence Berkeley National Laboratory(劳伦斯伯克利国家实验室)
Fiber-reinforced ceramic-matrix composites are advanced materials resistant to high temperatures, with application to aerospace engineering. Their analysis depends on the detection of embedded fibers, with semi-supervised techniques usually employed to separate fibers within the fiber beds. Here we present an open computational pipeline to detect fibers in ex-situ X-ray computed tomography fiber beds. To separate the fibers in these samples, we tested four different architectures of fully convolutional neural networks. When comparing our neural network approach to a semi-supervised one, we obt…
Istituto Italiano di Tecnologia(意大利理工学院);Fondazione Bruno Kessler(布鲁诺·凯斯勒基金会);Huawei Technologies Ltd.(华为技术有限公司);Università di Verona(维罗纳大学)
In this paper, we tackle the task of automatically analyzing 3D volumetric scans obtained from computed tomography (CT) devices. In particular, we address a particular task for which data is very limited: the segmentation of ancient Egyptian mummies CT scans. We aim at digitally unwrapping the mummy and identify different segments such as body, bandages and jewelry. The problem is complex because of the lack of annotated data for the different semantic regions to segment, thus discouraging the use of strongly supervised approaches. We, therefore, propose a weakly supervised and efficient inter…
National Institutes of Health Clinical Center(美国国立卫生研究院临床中心)
Organ segmentation is a prerequisite for a computer-aided diagnosis (CAD) system to detect pathologies and perform quantitative analysis. For anatomically high-variability abdominal organs such as the pancreas, previous segmentation works report low accuracies when comparing to organs like the heart or liver. In this paper, a fully-automated bottom-up method is presented for pancreas segmentation, using abdominal computed tomography (CT) scans. The method is based on a hierarchical two-tiered information propagation by classifying image patches. It labels superpixels as pancreas or not via poo…
Harvard Medical School(哈佛医学院);The University of Sydney(悉尼大学);The University of New South Wales(新南威尔士大学)
White matter fiber clustering (WMFC) enables parcellation of white matter tractography for applications such as disease classification and anatomical tract segmentation. However, the lack of ground truth and the ambiguity of fiber data (the points along a fiber can equivalently be represented in forward or reverse order) pose challenges to this task. We propose a novel WMFC framework based on unsupervised deep learning. We solve the unsupervised clustering problem as a self-supervised learning task. Specifically, we use a convolutional neural network to learn embeddings of input fibers, using …