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arXiv 1912.03383cs.CV

Deep Distance Transform for Tubular Structure Segmentation in CT Scans

Johns Hopkins University(约翰斯·霍普金斯大学);University of California San Diego(加利福尼亚大学圣迭戈分校);Tongji University(同济大学);The Johns Hopkins University School of Medicine(约翰斯·霍普金斯大学医学院)

Yan Wang, Xu Wei, Fengze Liu, Jieneng Chen, Yuyin Zhou, Wei Shen, Elliot K. Fishman, Alan L. Yuille

英文摘要:

Tubular structure segmentation in medical images, e.g., segmenting vessels in CT scans, serves as a vital step in the use of computers to aid in screening early stages of related diseases. But automatic tubular structure segmentation in CT scans is a challenging problem, due to issues such as poor contrast, noise and complicated background. A tubular structure usually has a cylinder-like shape which can be well represented by its skeleton and cross-sectional radii (scales). Inspired by this, we propose a geometry-aware tubular structure segmentation method, Deep Distance Transform (DDT), which combines intuitions from the classical distance transform for skeletonization and modern deep segmentation networks. DDT first learns a multi-task network to predict a segmentation mask for a tubular structure and a distance map. Each value in the map represents the distance from each tubular structure voxel to the tubular structure surface. Then the segmentation mask is refined by leveraging the shape prior reconstructed from the distance map. We apply our DDT on six medical image datasets. The experiments show that (1) DDT can boost tubular structure segmentation performance significantly (e.g., over 13% improvement measured by DSC for pancreatic duct segmentation), and (2) DDT additionally provides a geometrical measurement for a tubular structure, which is important for clinical diagnosis (e.g., the cross-sectional scale of a pancreatic duct can be an indicator for pancreatic cancer).

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