Purpose: Retinoblastoma (RB) is the most common eye tumor in childhood and can be treated external radiotherapy. The purpose of this work is to evaluate the adequacy of Monte Carlo simulations and the accuracy of a commercial treatment planning system by means of experimental measurements. Dose measurements in water were performed using a dedicated collimator.
Methods: A 6MV Varian Clinac 2100 C/D and a dedicated collimator are used for RB treatment. The collimator conforms a D-shaped off-axis field whose irradiated area can be either 5.2 or 3.1cm$^2$. Depth dose distributions and lateral profiles were measured and compared with Monte Carlo simulations run with PENELOPE and with calculations performed with the analytical anisotropic algorithm (AAA) using the gamma test.
Results: PENELOPE simulations agree well with the experimental data with discrepancies in the dose profiles less than 3mm of distance-to-agreement and 3% of dose. Discrepancies between the results of AAA and the experimental data reach 3mm and 6%. The agreement in the penumbra region between AAA and the experiment is noticeably worse than that between the latter and PENELOPE. The percentage of voxels passing the gamma test when comparing PENELOPE (AAA) and the experiment is on average 99% (93%) assuming a 3mm distance-to-agreement and a discrepancy of 3% of dose.
Conclusions: Although the discrepancies between AAA and experimental results are noticeable, it is possible to consider this algorithm for routine treatment planning of RB patients, provided the limitations of the algorithm are known and taken into account by the medical physicist. Monte Carlo simulation is essential for knowing these limitations. Monte Carlo simulation is required for optimizing the treatment technique and the dedicated collimator.
Low noise optimization of an electron beam current transformer for conventional radiotherapy up to ultra high dose rate irradiations
超高剂量率电子束，也称为FLASH放射治疗，在一些临床前癌症治疗研究中变得越来越重要。然而，由于在辐照会话期间使用的剂量率，迄今为止不存在实时剂量监测装置。在这项工作中，我们提出了一个束电流互感器（BCT）的发展，从铁磁组件的选择和实现的屏蔽的前端电子设计的基础上的跨阻抗电路，以执行低噪声优化的检测器。BCT样机能够监测1.2 \textmu A ~ 200 mA的束流，信号的上升时间常数优于20 ns，下降速率低于0.05 $\cdot$ s $^{-1}$。初步的现场测量也提出。目标是将实时测量射束电流的BCT系统与监测射束形状和位置的电离室相结合，以提供可靠的剂量监测系统。
Comment on "Comparing gold nano-particle enhanced radiotherapy with protons, megavoltage photons and kilovoltage photons: A Monte Carlo simulation" by Lin et al [Phys. Med. Biol. 59 (2014) 7675-7689]
Dependence of the Radical Dynamics on the Beam Temporal Profile in FLASH Radiotherapy
State Key Laboratory of Nuclear Physics and Technology and Institute of Heavy Ion Physics, School of Physics, Peking University（北京大学物理学院重离子物理研究所核物理与技术国家重点实验室）；Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Radiation Oncology, Peking University Cancer Hospital & Institute（北京大学肿瘤医院暨肿瘤研究所放射肿瘤科教育部癌变与转化研究重点实验室）；Department of Health Technology and Informatics, The Hong Kong Polytechnic University（香港理工大学健康技术与信息学系）；Beijing Laser Acceleration Innovation Center（北京激光加速器创新中心）；State Key Laboratory of Heavy Oil Processing, China University of Petroleum（中国石油大学（华东）重油加工国家重点实验室）；Guangdong Institute of Laser Plasma Accelerator Technology（广东激光等离子体加速器技术研究所）
A combined dose and microdosimetric modeling framework incorporating volume effects correlates with tissue sparing in proton minibeam radiotherapy
University of Trento（特伦托大学）；Trento Institute for Fundamental Physics and Application (TIFPA)（特伦托基础物理与应用研究所）；Istituto Nazionale Fisica Nucleare (INFN), Sezione di Catania（意大利国家核物理研究所（INFN），卡塔尼亚分部）；The Department of Physics & Astronomy at Louisiana State University (LSU)（路易斯安那州立大学物理与天文学系）；Department of Civil, Environmental and Mechanical Engineering, University of Trento（特伦托大学土木、环境与机械工程系）
Review of oxygen measurement and relevance to the mechanisms of FLASH radiotherapy
Thayer School of Engineering at Dartmouth（达特茅斯学院泰耶尔工程学院）；Giesel School of Medicine at Dartmouth（达特茅斯学院吉塞尔医学院）；University of Wisconsin School of Medicine and Public Health（威斯康星大学医学院和公共卫生学院）
Compact dose delivery of laser-accelerated high-energy electron beams towards radiotherapy applications
Zhengzhou University（郑州大学）；Tsinghua University（清华大学）；Beijing Academy of Artificial Intelligence（北京智源人工智能研究院）；Institute of High Energy Physics, Chinese Academy of Sciences（中国科学院高能物理研究所）
A feasible dose-volume estimation of radiotherapy treatment with optimal transport using a concept for transportation of Ricci-flat time-varying dose-volume
A volumetric Modulated Arc Therapy (VMAT) combined with deep inspiration breath hold (DIBH) technique for adjuvant irradiation for left sided breast cancer
Charge Collection Efficiency in Air-Vented Plane-Parallel Ionisation Chambers at Ultra-High Dose Rates: A Self-Consistent Garfield++ Monte Carlo Model Including Space-Charge Effects and Ion Recombination
Université libre de Bruxelles (ULB)（布鲁塞尔自由大学）；Ion Beam Applications SA（离子束应用公司）
DoseRAD2026 Challenge dataset: AI accelerated photon and proton dose calculation for radiotherapy
Department of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany（路德维希-马克西米利安慕尼黑大学医学院放射肿瘤科，慕尼黑大学医院，慕尼黑，德国）；Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany（放射肿瘤学中的医学物理部门，德国癌症研究中心（DKFZ），海德堡，德国）；National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Heidelberg, Germany（肿瘤放射研究国家中心（NCRO），海德堡放射肿瘤学研究所（HIRO），海德堡，德国）；GSI Helmholtzzentrum für Schwerionenforschung, Biophysics Department, Darmstadt, Germany（重离子研究中心GSI，生物物理部门，达姆施塔特，德国）；Department of Physics and Astronomy, Heidelberg University, Heidelberg, Germany（海德堡大学物理与天文学系，海德堡，德国）；Institute of Biomedical Engineering, Karlsruhe Institute of Technology, Baden-Württemberg, Germany（生物医学工程研究所，卡尔斯鲁厄理工学院，巴登-符腾堡，德国）；Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands（放射治疗科，乌得勒支大学医学中心，乌得勒支，荷兰）；Department of Radiation Oncology, Amsterdam UMC location Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Cancer Treatment and Quality of Life, Amsterdam, Netherlands（放射肿瘤学系，阿姆斯特丹自由大学阿姆斯特丹校区，阿姆斯特丹癌症中心，癌症治疗与生活质量，阿姆斯特丹，荷兰）；Center for Proton Therapy, Paul Scherrer Institute (PSI), Villigen, Switzerland（质子治疗中心，瑞士保罗·谢尔研究所（PSI），维利根，瑞士）；Department of Radiation Oncology, University Hospital Heidelberg, Heidelberg, Germany（放射肿瘤学系，海德堡大学医院，海德堡，德国）；Radiation Physics, Department of Hematology, Oncology, and Radiation Physics, Skåne University Hospital, Lund, Sweden（放射物理，血液学、肿瘤学和放射物理部门，斯德哥尔摩大学医院，吕勒奥，瑞典）；Delft University of Technology, Department of Radiation Science and Technology, Delft, Netherlands（代尔夫特理工大学，辐射科学与技术系，代尔夫特，荷兰）；Radformation Inc., New York, US（Radformation公司，纽约，美国）
Focal-point scanning for dose delivery and optimization with focused laser-accelerated very-high-energy electron beams
Zhengzhou University（郑州大学）；Tsinghua University（清华大学）；Microsoft Research, AI for Science（微软研究院 AI for 科学）；The First Affiliated Hospital of Zhengzhou University（郑州大学第一附属医院）；University of Michigan, Ann Arbor（密歇根大学安娜堡分校）；National Institute of Metrology（中国计量科学研究院）
