arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 1808.07977physics.flu-dyn
收藏

血液本构模型的比较

A Comparison of Constitutive Models of Blood

Corina S. Drapaca, Zhifeng Zhang, Ruifan Meng

摘要:

准确预测血液力学行为的数学模型有助于开发与临床应用相关的生物医学设备和药物。文献中存在的模型足够复杂,以符合各种体外实验观察结果。最新的技术进步开启了研究体内血流的可能性,这可能在创造用于健康监测和治疗目的的生物相容性植入物方面发挥重要作用。然而,大多数现有的模型可能无法预测体内的血液行为,因为它们需要许多难以在体内找到的参数,并且它们没有结合特定于活体中血流的相关耦合化学机械动力学。最近,我们使用Drapaca和Sivaloganathan [J. Elast.,107:105-123,2012]以研究血液循环。在这个数学公式中,变形张量速率的空间导数用Caputo分数导数表示。本文的目的是通过一个轴对称的圆形刚性和不可渗透的管道,其中的血液是由上述分数模型,卡森的模型,和幂律模型描述的Poiffille流动的血液进行比较。虽然这三种模型的速度分布看起来相似,分数模型提供了一个更好的拟合发表的实验数据。

英文摘要:

Mathematical models that accurately predict the mechanical behavior of blood can contribute to the development of biomedical devices and medications which are relevant in clinical applications. The models existing in the literature are complex enough in order to agree with various in vitro experimental observations. Latest technological advancements opened the possibility of studying blood flow in vivo which could play an important role in the creation of biocompatible implants for health monitoring and treatment purposes. However, most of existing models may fail to predict blood behavior in vivo because they require many parameters which are difficult to find in vivo and they do not incorporate pertinent coupled chemo-mechanical dynamics specific to blood flow in a living body. Recently, we used the fractional model of continuum mechanics proposed by Drapaca and Sivaloganathan [J. Elast.,107: 105-123, 2012] to study blood circulation. In this mathematical formulation the spatial derivatives of the rate of deformation tensor are expressed using Caputo fractional derivatives. The aim of this paper is to compare the Poiseuille flows of blood through an axi-symmetric circular rigid and impermeable pipe where the blood is described by the above mentioned fractional model, the Casson's model, and the power law model. Although the velocity profiles of these three models look similar, the fractional model provides a better fitting to published experimental data.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑