双凹-盘状胶囊在拉伸流和电场中的变形
Deformation of a biconcave-discoid capsule in extensional flow and electric field
摘要：
除了理解红细胞（RBC）在血流中的行为之外，双凹盘状（红细胞的经验形状）胶囊在生物流体动力学和流变学领域中有许多应用。因此，进行了详细的分析，以了解单轴拉伸流和电场的RBC和双凹盘状聚合物胶囊在轴对称制度的变形的影响。采用Stokes流的轴对称边界积分方法，以Skalak膜本构关系作为区域不可压RBC/双凹盘状囊膜的模型，数值计算了瞬态变形。当弹性能被粘性或麦克斯韦电应力克服时，观察到显著的双凹盘状到长球形的转变。此外，膜应力的意义，在变形过程中，并在稳定状态和不同的变形模式。这项研究将有助于设计一个在电场作用下的生物细胞人工系统。
英文摘要：
Biconcave-discoid (empirical shape of a red blood cell) capsule finds numerous applications in the field of bio-fluid dynamics and rheology, apart from understanding the behavior of red blood cells (RBC) in blood flow. A detailed analysis is, therefore, carried out to understand the effects of the uniaxial extensional flow and electric field on the deformation of a RBC and biconcave-discoid polymeric capsule in the axisymmetric regime. The transient deformation is computed numerically using axisymmetric boundary integral method for Stokes flow considering the Skalak membrane constitutive law as the model for the area incompressible RBC/biconcave-discoid capsule membrane. A remarkable biconcave-discoid to prolate spheroid transition is observed when the elastic energy is overcome by the viscous or Maxwell electric stresses. Moreover, the significance of membrane stresses developed during the deformation and at steady state and different modes of deformation are presented. This study should be useful in designing an artificial system involving biological cells under an electric field.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
