Breast cancer is the most common cancer in women worldwide. The most common screening technology is mammography. To reduce the cost and workload of radiologists, we propose a computer aided detection approach for classifying and localizing calcifications and masses in mammogram images. To improve on conventional approaches, we apply deep convolutional neural networks (CNN) for automatic feature learning and classifier building. In computer-aided mammography, deep CNN classifiers cannot be trained directly on full mammogram images because of the loss of image details from resizing at input layers. Instead, our classifiers are trained on labelled image patches and then adapted to work on full mammogram images for localizing the abnormalities. State-of-the-art deep convolutional neural networks are compared on their performance of classifying the abnormalities. Experimental results indicate that VGGNet receives the best overall accuracy at 92.53\% in classifications. For localizing abnormalities, ResNet is selected for computing class activation maps because it is ready to be deployed without structural change or further training. Our approach demonstrates that deep convolutional neural network classifiers have remarkable localization capabilities despite no supervision on the location of abnormalities is provided.
IMT School for Advanced Studies Lucca（卢卡IMT高等研究院）；Fondazione Gabriele Monasterio（加布里埃莱·莫纳斯特里奥基金会）；Azienda USL Toscana Nord Ovest (ATNO)（托斯卡纳西北部地方卫生局（ATNO））
Cluster of microcalcifications can be an early sign of breast cancer. In this paper we propose a novel approach based on convolutional neural networks for the detection and segmentation of microcalcification clusters. In this work we used 283 mammograms to train and validate our model, obtaining an accuracy of 98.22% in the detection of preliminary suspect regions and of 97.47% in the segmentation task. Our results show how deep learning could be an effective tool to effectively support radiologists during mammograms examination.
In this paper, we describe our method for classification of brain magnetic resonance (MR) images into different abnormalities and healthy classes based on the deep neural network. We propose our method to detect high and low-grade glioma, multiple sclerosis, and Alzheimer diseases as well as healthy cases. Our network architecture has ten learning layers that include seven convolutional layers and three fully connected layers. We have achieved a promising result in five categories of brain images (classification task) with 95.7% accuracy.
Isfahan University of Technology（伊斯法罕理工大学）；University of Michigan（密歇根大学）
Automating classification and segmentation process of abnormal regions in different body organs has a crucial role in most of medical imaging applications such as funduscopy, endoscopy, and dermoscopy. Detecting multiple abnormalities in each type of images is necessary for better and more accurate diagnosis procedure and medical decisions. In recent years portable medical imaging devices such as capsule endoscopy and digital dermatoscope have been introduced and made the diagnosis procedure easier and more efficient. However, these portable devices have constrained power resources and limited…
University College London（伦敦大学学院）；King’s College London（伦敦国王学院）
State-of-the-art deep learning methods for image processing are evolving into increasingly complex meta-architectures with a growing number of modules. Among them, region-based fully convolutional networks (R-FCN) and deformable convolutional nets (DCN) can improve CAD for mammography: R-FCN optimizes for speed and low consumption of memory, which is crucial for processing the high resolutions of to 50 micrometers used by radiologists. Deformable convolution and pooling can model a wide range of mammographic findings of different morphology and scales, thanks to their versatility. In this stud…
Chest X-Rays (CXRs) are widely used for diagnosing abnormalities in the heart and lung area. Automatically detecting these abnormalities with high accuracy could greatly enhance real world diagnosis processes. Lack of standard publicly available dataset and benchmark studies, however, makes it difficult to compare various detection methods. In order to overcome these difficulties, we have used a publicly available Indiana CXR, JSRT and Shenzhen dataset and studied the performance of known deep convolutional network (DCN) architectures on different abnormalities. We find that the same DCN archi…
A Lightweight CNN Integrated Compact Convolutional Transformer for Multi-Scale Feature Learning and reducing computational complexity for breast cancer mammography image detection and classification
PDPM Indian Institute of Information Technology, Design and Manufacturing（PDPM印度信息技术设计与制造学院）
Wireless Capsule Endoscopy is one of the most advanced non-invasive methods for the examination of gastrointestinal tracts. An intelligent computer-aided diagnostic system for detecting gastrointestinal abnormalities like polyp, bleeding, inflammation, etc. is highly exigent in wireless capsule endoscopy image analysis. Abnormalities greatly differ in their shape, size, color, and texture, and some appear to be visually similar to normal regions. This poses a challenge in designing a binary classifier due to intra-class variations. In this study, a hybrid convolutional neural network is propos…
Road accident can be triggered by wet road because it decreases skid resistance. To prevent the road accident, detecting road surface abnomality is highly useful. In this paper, we propose the deep learning based cost-effective real-time anomaly detection architecture, naming with non-compression auto-encoder (NCAE). The proposed architecture can reflect forward and backward causality of time series information via convolutional operation. Moreover, the above architecture shows higher anomaly detection performance of published anomaly detection model via experiments. We conclude that NCAE as a…
We present a novel Convolutional Neural Network (CNN) based approach for one class classification. The idea is to use a zero centered Gaussian noise in the latent space as the pseudo-negative class and train the network using the cross-entropy loss to learn a good representation as well as the decision boundary for the given class. A key feature of the proposed approach is that any pre-trained CNN can be used as the base network for one class classification. The proposed One Class CNN (OC-CNN) is evaluated on the UMDAA-02 Face, Abnormality-1001, FounderType-200 datasets. These datasets are rel…
Diagnostic Image Analysis Group, Department of Radiology and Nuclear Medicine, RadboudUMC Nijmegen（拉德堡德大学医学中心放射与核医学科诊断影像分析组）
We investigate the addition of symmetry and temporal context information to a deep Convolutional Neural Network (CNN) with the purpose of detecting malignant soft tissue lesions in mammography. We employ a simple linear mapping that takes the location of a mass candidate and maps it to either the contra-lateral or prior mammogram and Regions Of Interest (ROI) are extracted around each location. We subsequently explore two different architectures (1) a fusion model employing two datastreams were both ROIs are fed to the network during training and testing and (2) a stage-wise approach where a s…
Segmentation has been a major task in neuroimaging. A large number of automated methods have been developed for segmenting healthy and diseased brain tissues. In recent years, deep learning techniques have attracted a lot of attention as a result of their high accuracy in different segmentation problems. We present a new deep learning based segmentation method, DeepMRSeg, that can be applied in a generic way to a variety of segmentation tasks. The proposed architecture combines recent advances in the field of biomedical image segmentation and computer vision. We use a modified UNet architectur…
Virginia Polytechnic Institute and State University (Virginia Tech)（弗吉尼亚理工大学（Virginia Tech））；Department of Mechanical Engineering（机械工程系）；Autonomous Systems and Intelligent Machines (ASIM) Lab（自主系统与智能机器（ASIM）实验室）；Graduate Research Assistant（研究生研究助理）
This paper introduces MuRAD (Musculoskeletal Radiograph Abnormality Detection tool), a tool that can help radiologists automate the detection of abnormalities in musculoskeletal radiographs (bone X-rays). MuRAD utilizes a Convolutional Neural Network (CNN) that can accurately predict whether a bone X-ray is abnormal, and leverages Class Activation Map (CAM) to localize the abnormality in the image. MuRAD achieves an F1 score of 0.822 and a Cohen's kappa of 0.699, which is comparable to the performance of expert radiologists.
Escola Politécnica, Universidade de São Paulo（圣保罗大学理工学院）；Instituto do Câncer do Estado de São Paulo（圣保罗州癌症研究所）；Faculdade de Medicina, Universidade de São Paulo（圣保罗大学医学院）
Some recent studies have described deep convolutional neural networks to diagnose breast cancer in mammograms with similar or even superior performance to that of human experts. One of the best techniques does two transfer learnings: the first uses a model trained on natural images to create a "patch classifier" that categorizes small subimages; the second uses the patch classifier to scan the whole mammogram and create the "single-view whole-image classifier". We propose to make a third transfer learning to obtain a "two-view classifier" to use the two mammographic views: bilateral craniocaud…
CapsoNet: A CNN-Transformer Ensemble for Multi-Class Abnormality Detection in Video Capsule Endoscopy
Department of Computer Science and Engineering, National Institute of Technology Rourkela（计算机科学与工程系，印度国立技术学院鲁尔克ela分校）；Department of Artificial Intelligence and Data Sciences, Indira Gandhi Delhi Technical University for Women（人工智能与数据科学系，印度甘地德里技术女子大学）
Early detection of breast cancer in mammography screening via deep-learning based computer-aided detection systems shows promising potential in improving the curability and mortality rates of breast cancer. However, many clinical centres are restricted in the amount and heterogeneity of available data to train such models to (i) achieve promising performance and to (ii) generalise well across acquisition protocols and domains. As sharing data between centres is restricted due to patient privacy concerns, we propose a potential solution: sharing trained generative models between centres as subs…
Mekelle Institute of Technology - Mekelle University（梅克莱大学梅克莱理工学院）；FDRE Ministry of Innovation and Technology（埃塞俄比亚联邦民主共和国创新与技术部）；College of Health Science - Mekelle University（梅克莱大学健康科学学院）
Breast cancer is prevalent in Ethiopia that accounts 34% among women cancer patients. The diagnosis technique in Ethiopia is manual which was proven to be tedious, subjective, and challenging. Deep learning techniques are revolutionizing the field of medical image analysis and hence in this study, we proposed Convolutional Neural Networks (CNNs) for breast mass detection so as to minimize the overheads of manual analysis. CNN architecture is designed for the feature extraction stage and adapted both the Region Proposal Network (RPN) and Region of Interest (ROI) portion of the faster R-CNN for …
Image-Based Breast Implant Detection for Mammography Dataset Curation and Near-Real-Time Deployment: Comparing Foundation Models and Task-Specific Convolutional Models
Emory University School of Medicine（埃默里大学医学院）；University of Maryland（马里兰大学）
Automatic identification of patients with luminal and non-luminal subtypes during a routine mammography screening can support clinicians in streamlining breast cancer therapy planning. Recent machine learning techniques have shown promising results in molecular subtype classification in mammography; however, they are highly dependent on pixel-level annotations, handcrafted, and radiomic features. In this work, we provide initial insights into the luminal subtype classification in full mammogram images trained using only image-level labels. Transfer learning is applied from a breast abnormality…
New York University（纽约大学）；Northwell Health（诺斯韦尔健康）
Applying deep learning methods to mammography assessment has remained a challenging topic. Dense noise with sparse expressions, mega-pixel raw data resolution, lack of diverse examples have all been factors affecting performance. The lack of pixel-level ground truths have especially limited segmentation methods in pushing beyond approximately bounding regions. We propose a classification approach grounded in high performance tissue assessment as an alternative to all-in-one localization and assessment models that is also capable of pinpointing the causal pixels. First, the objective of the mam…
University of São Paulo（圣保罗大学）；Eco & Mama Diagnóstico Digital（Eco & Mama数字诊断公司）
Early detection of breast cancer can increase treatment efficiency. Architectural Distortion (AD) is a very subtle contraction of the breast tissue and may represent the earliest sign of cancer. Since it is very likely to be unnoticed by radiologists, several approaches have been proposed over the years but none using deep learning techniques. To train a Convolutional Neural Network (CNN), which is a deep neural architecture, is necessary a huge amount of data. To overcome this problem, this paper proposes a data augmentation approach applied to clinical image dataset to properly train a CNN. …
University of Genova（热那亚大学）；University of Trento（特伦托大学）；SAP SE（思爱普公司）；Istituto Italiano di Tecnologia（意大利理工学院）；Polytechnique Montréal（蒙特利尔综合理工学院）
Most of the crowd abnormal event detection methods rely on complex hand-crafted features to represent the crowd motion and appearance. Convolutional Neural Networks (CNN) have shown to be a powerful tool with excellent representational capacities, which can leverage the need for hand-crafted features. In this paper, we show that keeping track of the changes in the CNN feature across time can facilitate capturing the local abnormality. We specifically propose a novel measure-based method which allows measuring the local abnormality in a video by combining semantic information (inherited from ex…
Understanding model predictions is critical in healthcare, to facilitate rapid verification of model correctness and to guard against use of models that exploit confounding variables. We introduce the challenging new task of explainable multiple abnormality classification in volumetric medical images, in which a model must indicate the regions used to predict each abnormality. To solve this task, we propose a multiple instance learning convolutional neural network, AxialNet, that allows identification of top slices for each abnormality. Next we incorporate HiResCAM, an attention mechanism, to …
Google-MedGemma Based Abnormality Detection in Musculoskeletal radiographs
University of Texas at Arlington, Texas, United States（德克萨斯大学阿灵顿分校）；University of Engineering and Management, Kolkata, India（工程与管理大学）；Sardar Vallabhbhai National Institute of Technology, Surat, India（萨达尔·瓦拉布尔希国家理工学院）
University of Girona（赫罗纳大学）；Parc Tauli Hospital Universitari（帕克陶利大学医院）；Institut d’Investigacio i Innovacio Parc Tauli (I3PT)（帕克陶利研究与创新研究所（I3PT））
Early detection of breast cancer has a major contribution to curability, and using mammographic images, this can be achieved non-invasively. Supervised deep learning, the dominant CADe tool currently, has played a great role in object detection in computer vision, but it suffers from a limiting property: the need of a large amount of labelled data. This becomes stricter when it comes to medical datasets which require high-cost and time-consuming annotations. Furthermore, medical datasets are usually imbalanced, a condition that often hinders classifiers performance. The aim of this paper is to…
Purdue University（普渡大学）；Ahsanullah University of Science and Technology（阿萨努拉科技大学）
Anomaly detection (AD) in a surveillance scenario is an emerging and challenging field of research. For autonomous vehicles like drones or cars, it is immensely important to distinguish between normal and abnormal states in real-time. Additionally, we also need to detect any device malfunction. But the nature and degree of abnormality may vary depending upon the actual environment and adversary. As a result, it is impractical to model all cases a-priori and use supervised methods to classify. Also, an autonomous vehicle provides various data types like images and other analog or digital sensor…
Mammography is the most widely used method to screen breast cancer. Because of its mostly manual nature, variability in mass appearance, and low signal-to-noise ratio, a significant number of breast masses are missed or misdiagnosed. In this work, we present how Convolutional Neural Networks can be used to directly classify pre-segmented breast masses in mammograms as benign or malignant, using a combination of transfer learning, careful pre-processing and data augmentation to overcome limited training data. We achieve state-of-the-art results on the DDSM dataset, surpassing human performance,…
The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer on screening mammograms using an "end-to-end" training approach that efficiently leverages training datasets with either complete clinical annotation or only the cancer status (label) of the whole image. In this approach, lesion annotations are required only in the initial training stage, and subsequent stages require only image-level labels, eliminating the …
Machine learning models for radiology benefit from large-scale data sets with high quality labels for abnormalities. We curated and analyzed a chest computed tomography (CT) data set of 36,316 volumes from 19,993 unique patients. This is the largest multiply-annotated volumetric medical imaging data set reported. To annotate this data set, we developed a rule-based method for automatically extracting abnormality labels from free-text radiology reports with an average F-score of 0.976 (min 0.941, max 1.0). We also developed a model for multi-organ, multi-disease classification of chest CT volum…
Breast cancer is considered as the most fatal type of cancer among women worldwide and it is crucially important to be diagnosed at its early stages. In the current study, we aim to represent a fast and efficient framework which consists of two main parts:1- image classification, and 2- tumor region segmentation. At the initial stage, the images are classified into the two categories of normal and abnormal. Since the Deep Neural Networks have performed successfully in machine vision task, we would employ the convolutional neural networks for the classification of images. In the second stage, t…
Multivariate Analysis on Performance Gaps of Artificial Intelligence Models in Screening Mammography
Kennesaw State University（肯尼索州立大学）；Emory University（埃默里大学）；Washington University in St. Louis School of Medicine（圣路易斯华盛顿大学医学院）；Mayo Clinic Arizona（梅奥诊所亚利桑那分院）；Arizona State University（亚利桑那州立大学）；York University（约克大学）
Computer Vision and Robotics Institute, University of Girona（赫罗纳大学计算机视觉与机器人研究所）；University of Barcelona（巴塞罗那大学）；Faculty of Medicine, University of Girona（赫罗纳大学医学院）；Parc Tauli Hospital Universitari（陶利公园大学医院）；Institut d’Investigacio Parc Tauli I3PT（陶利公园研究所）
Medical image synthesis has gained a great focus recently, especially after the introduction of Generative Adversarial Networks (GANs). GANs have been used widely to provide anatomically-plausible and diverse samples for augmentation and other applications, including segmentation and super resolution. In our previous work, Deep Convolutional GANs were used to generate synthetic mammogram lesions, masses mainly, that could enhance the classification performance in imbalanced datasets. In this new work, a deeper investigation was carried out to explore other aspects of the generated images evalu…
Temporal activity localization in long videos is an important problem. The cost of obtaining frame level label for long Wireless Capsule Endoscopy (WCE) videos is prohibitive. In this paper, we propose an end-to-end temporal abnormality localization for long WCE videos using only weak video level labels. Physicians use Capsule Endoscopy (CE) as a non-surgical and non-invasive method to examine the entire digestive tract in order to diagnose diseases or abnormalities. While CE has revolutionized traditional endoscopy procedures, a single CE examination could last up to 8 hours generating as muc…
Indian Institute of Technology Kharagpur（印度理工学院卡拉格普尔分校）；Intel Technology India Pvt. Ltd.（英特尔印度技术私人有限公司）
Early works on medical image compression date to the 1980's with the impetus on deployment of teleradiology systems for high-resolution digital X-ray detectors. Commercially deployed systems during the period could compress 4,096 x 4,096 sized images at 12 bpp to 2 bpp using lossless arithmetic coding, and over the years JPEG and JPEG2000 were imbibed reaching upto 0.1 bpp. Inspired by the reprise of deep learning based compression for natural images over the last two years, we propose a fully convolutional autoencoder for diagnostically relevant feature preserving lossy compression. This is f…
NYU Langone Health（纽约大学朗格尼医学中心）；Jagiellonian University（雅盖隆大学）；New York University（纽约大学）
3D imaging enables accurate diagnosis by providing spatial information about organ anatomy. However, using 3D images to train AI models is computationally challenging because they consist of 10x or 100x more pixels than their 2D counterparts. To be trained with high-resolution 3D images, convolutional neural networks resort to downsampling them or projecting them to 2D. We propose an effective alternative, a neural network that enables efficient classification of full-resolution 3D medical images. Compared to off-the-shelf convolutional neural networks, our network, 3D Globally-Aware Multiple …
University of Engineering and Technology Taxila（塔克西拉工程技术大学）；University of Surrey（萨里大学）；King Abdul Aziz University（阿卜杜勒·阿齐兹国王大学）；King Saud University（沙特国王大学）
The science of solving clinical problems by analyzing images generated in clinical practice is known as medical image analysis. The aim is to extract information in an effective and efficient manner for improved clinical diagnosis. The recent advances in the field of biomedical engineering has made medical image analysis one of the top research and development area. One of the reason for this advancement is the application of machine learning techniques for the analysis of medical images. Deep learning is successfully used as a tool for machine learning, where a neural network is capable of au…
DEIM, Universitat Rovira i Virgili, Spain（西班牙塔拉戈纳大学（DEIM））；Imaging Informatics Division, Bioinformatics Institute, Singapore（新加坡生物信息学研究所成像信息学部门）；Kayakalp Hospital, 110084 New Delhi, India（印度新德里Kayakalp医院）；Hospital Universitari Sant Joan de Reus, Spain（西班牙圣胡安·德雷斯医院）
This paper proposes a novel approach based on conditional Generative Adversarial Networks (cGAN) for breast mass segmentation in mammography. We hypothesized that the cGAN structure is well-suited to accurately outline the mass area, especially when the training data is limited. The generative network learns intrinsic features of tumors while the adversarial network enforces segmentations to be similar to the ground truth. Experiments performed on dozens of malignant tumors extracted from the public DDSM dataset and from our in-house private dataset confirm our hypothesis with very high Dice c…
Mammography is the most widely used gold standard for screening breast cancer, where, mass detection is considered as the prominent step. Detecting mass in the breast is, however, an arduous problem as they usually have large variations between them in terms of shape, size, boundary, and texture. In this literature, the process of mass detection is automated with the use of transfer learning techniques of Deep Convolutional Neural Networks (DCNN). Pre-trained VGG19 network is used to extract features which are then followed by bagged decision tree for features selection and then a Support Vect…
Breast cancer has the highest incidence and second highest mortality rate for women in the US. Our study aims to utilize deep learning for benign/malignant classification of mammogram tumors using a subset of cases from the Digital Database of Screening Mammography (DDSM). Though it was a small dataset from the view of Deep Learning (about 1000 patients), we show that currently state of the art architectures of deep learning can find a robust signal, even when trained from scratch. Using convolutional neural networks (CNNs), we are able to achieve an accuracy of 85% and an ROC AUC of 0.91, whi…
Princeton University（普林斯顿大学）；The Chinese University of Hong Kong（香港中文大学）；Microsoft（微软）；UCLA（加州大学洛杉矶分校）；Beth Israel Deaconess Medical Center（贝斯以色列女执事医疗中心）；Microsoft Research New England（微软新英格兰研究院）；VSCO
We propose DeepMiner, a framework to discover interpretable representations in deep neural networks and to build explanations for medical predictions. By probing convolutional neural networks (CNNs) trained to classify cancer in mammograms, we show that many individual units in the final convolutional layer of a CNN respond strongly to diseased tissue concepts specified by the BI-RADS lexicon. After expert annotation of the interpretable units, our proposed method is able to generate explanations for CNN mammogram classification that are consistent with ground truth radiology reports on the Di…
Interpretable pap smear cell representation for cervical cancer screening
Kyungpook National University（庆北国立大学）；Clinical Omics Institute, Kyungpook National University（庆北国立大学临床组学研究所）；Kyungpook National University Chilgok Hospital（庆北国立大学漆谷医院）
Purdue University（普渡大学）；Ahsanullah University of Science and Technology（阿赫桑乌拉科技大学）
Autonomous aerial surveillance using drone feed is an interesting and challenging research domain. To ensure safety from intruders and potential objects posing threats to the zone being protected, it is crucial to be able to distinguish between normal and abnormal states in real-time. Additionally, we also need to consider any device malfunction. However, the inherent uncertainty embedded within the type and level of abnormality makes supervised techniques less suitable since the adversary may present a unique anomaly for intrusion. As a result, an unsupervised method for anomaly detection is …
Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated methods for DBT classification are handling the variable number of slices and retaining slice-to-slice changes. We propose a novel deep 2D convolutional neural network (CNN) architecture for DBT classification that simultaneously overcomes both challenges. Our approach operates on the full volume, regardless of the number of slices, and allows the use of pre-trai…
Universitat Rovira i Virgili（罗维拉-威尔吉利大学）；Bioinformatics Institute, A*STAR（新加坡科技研究局生物信息学研究所）；Hospital Universitari Sant Joan de Reus（雷乌斯圣琼大学医院）
Mammogram inspection in search of breast tumors is a tough assignment that radiologists must carry out frequently. Therefore, image analysis methods are needed for the detection and delineation of breast masses, which portray crucial morphological information that will support reliable diagnosis. In this paper, we proposed a conditional Generative Adversarial Network (cGAN) devised to segment a breast mass within a region of interest (ROI) in a mammogram. The generative network learns to recognize the breast mass area and to create the binary mask that outlines the breast mass. In turn, the ad…
Screening mammography is an important front-line tool for the early detection of breast cancer, and some 39 million exams are conducted each year in the United States alone. Here, we describe a multi-scale convolutional neural network (CNN) trained with a curriculum learning strategy that achieves high levels of accuracy in classifying mammograms. Specifically, we first train CNN-based patch classifiers on segmentation masks of lesions in mammograms, and then use the learned features to initialize a scanning-based model that renders a decision on the whole image, trained end-to-end on outcome …
Comparative Analysis of Segment Anything Model and U-Net for Breast Tumor Detection in Ultrasound and Mammography Images
Florida Atlantic University（佛罗里达大西洋大学）；University of Massachusetts Lowell（马萨诸塞大学洛厄尔分校）；Shahid Beheshti University of Medical Sciences（沙希德·贝赫什提医科大学）；Missouri University of Science and Technology（密苏里科技大学）；Florida International University（佛罗里达国际大学）
Breast cancer is the second leading cause of cancer death among women worldwide. Nevertheless, it is also one of the most treatable malignances if detected early. Screening for breast cancer with digital mammography (DM) has been widely used. However it demonstrates limited sensitivity for women with dense breasts. An emerging technology in the field is contrast-enhanced digital mammography (CEDM), which includes a low energy (LE) image similar to DM, and a recombined image leveraging tumor neoangiogenesis similar to breast magnetic resonance imaging (MRI). CEDM has shown better diagnostic acc…
Shenzhen University（深圳大学）；Tencent Holdings Limited（腾讯控股有限公司）；Nvidia Corporation（英伟达公司）；National Institutes of Health（美国国立卫生研究院）
Fine-grained classification of cervical cells into different abnormality levels is of great clinical importance but remains very challenging. Contrary to traditional classification methods that rely on hand-crafted or engineered features, convolution neural network (CNN) can classify cervical cells based on automatically learned deep features. However, CNN in previous studies do not involve cell morphological information, and it is unknown whether morphological features can be directly modeled by CNN to classify cervical cells. This paper presents a CNN-based method that combines cell image ap…
Universidad Técnica Particular de Loja（洛哈技术大学）；Universitat Politécnica de Valencia（瓦伦西亚理工大学）；University of Waterloo（滑铁卢大学）
Breast cancer is the most common invasive cancer in women, and the second main cause of death. Breast cancer screening is an efficient method to detect indeterminate breast lesions early. The common approaches of screening for women are tomosynthesis and mammography images. However, the traditional manual diagnosis requires an intense workload by pathologists, who are prone to diagnostic errors. Thus, the aim of this study is to build a deep convolutional neural network method for automatic detection, segmentation, and classification of breast lesions in mammography images. Based on deep learn…
