Convolutional Neural Networks (CNN) have emerged as powerful tools for learning discriminative image features. In this paper, we propose a framework of 3-D fully CNN models for Glioblastoma segmentation from multi-modality MRI data. By generalizing CNN models to true 3-D convolutions in learning 3-D tumor MRI data, the proposed approach utilizes a unique network architecture to decouple image pixels. Specifically, we design a convolutional layer with pre-defined Difference- of-Gaussian (DoG) filters to perform true 3-D convolution incorporating local neighborhood information at each pixel. We then use three trained convolutional layers that act to decouple voxels from the initial 3-D convolution. The proposed framework allows identification of high-level tumor structures on MRI. We evaluate segmentation performance on the BRATS segmentation dataset with 274 tumor samples. Extensive experimental results demonstrate encouraging performance of the proposed approach comparing to the state-of-the-art methods. Our data-driven approach achieves a median Dice score accuracy of 89% in whole tumor glioblastoma segmentation, revealing a generalized low-bias possibility to learn from medium-size MRI datasets.
The glioblastoma multiforme is the most common malignant primary brain tumor and is one of the highest malignant human neoplasms. During the course of disease, the evaluation of tumor volume is an essential part of the clinical follow-up. However, manual segmentation for acquisition of tumor volume is a time-consuming process. In this paper, a new approach for the automatic segmentation and volume determination of glioblastomas (glioblastoma multiforme) is presented and evaluated. The approach uses a user-defined seed point inside the glioma to set up a directed 3D graph. The nodes of the grap…
National University of Singapore（新加坡国立大学）；University of Moratuwa（莫拉图瓦大学）
The accurate prognosis of Glioblastoma Multiforme (GBM) plays an essential role in planning correlated surgeries and treatments. The conventional models of survival prediction rely on radiomic features using magnetic resonance imaging (MRI). In this paper, we propose a radiogenomic overall survival (OS) prediction approach by incorporating gene expression data with radiomic features such as shape, geometry, and clinical information. We exploit TCGA (The Cancer Genomic Atlas) dataset and synthesize the missing MRI modalities using a fully convolutional network (FCN) in a conditional Generative …
Postoperative glioblastoma segmentation: Development of a fully automated pipeline using deep convolutional neural networks and comparison with currently available models
Río Hortega University Hospital（里奥·奥尔特加大学医院）；Universidad de Valladolid（巴利亚多利德大学）；Center for Biomedical Research in Network of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN)（生物工程、生物材料和纳米医学网络生物医学研究中心）；Albacete University Hospital（阿尔瓦塞特大学医院）；La Princesa University Hospital（拉普林塞萨大学医院）；UiT The Arctic University of Norway（挪威北极大学）；University Hospital of North Norway（北挪威大学医院）；St. Olavs University Hospital（圣奥拉夫大学医院）；Norwegian University of Science and Technology（挪威科技大学）；St. Olavs Hospital, Trondheim University Hospital（圣奥拉夫医院，特隆赫姆大学医院）；de Octubre University Hospital (i + 12)（10月12日大学医院）；Complutense University（马德里康普顿斯大学）；Instituto de Investigación Sanitaria, 12 de Octubre University Hospital (i + 12)（10月12日大学医院卫生研究所）；Institute for Research in Mathematics (IMUVA), University of Valladolid（巴利亚多利德大学数学研究所）
University of Cambridge（剑桥大学）；Shanghai General Hospital（上海市第一人民医院）；Shanghai Jiao Tong University（上海交通大学）；Southern University of Science and Technology（南方科技大学）；University of Bath（巴斯大学）
We present an Expectation-Maximization (EM) Regularized Deep Learning (EMReDL) model for weakly supervised tumor segmentation. The proposed framework is tailored to glioblastoma, a type of malignant tumor characterized by its diffuse infiltration into the surrounding brain tissue, which poses significant challenge to treatment target and tumor burden estimation using conventional structural MRI. Although physiological MRI provides more specific information regarding tumor infiltration, the relatively low resolution hinders a precise full annotation. This has motivated us to develop a weakly su…
Department of Health Technology, Technical University of Denmark（丹麦技术大学健康技术系）；Department of Oncology, The Finsen Center, Rigshospitalet（哥本哈根大学医院芬森中心肿瘤学系）；Department of Clinical Physiology, Nuclear Medicine and PET, Center of Diagnostic Investigation, Rigshospitalet（哥本哈根大学医院诊断研究中心临床生理学、核医学与正电子发射断层扫描科）；Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School（哈佛医学院麻省总医院Athinoula A. Martinos生物医学成像中心）
Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties generalizing across data acquisitions, or are only applicable to pre-operative MR data. In this paper we aim to address these issues by introducing novel imaging features that can be automatically computed from MR images and fed into machine learning models to predict patient survival. The features we propose have a direct biological interpretation: They measure the…
The Rio Hortega University Hospital Glioblastoma dataset: a comprehensive collection of preoperative, early postoperative and recurrence MRI scans (RHUH-GBM)
Glioblastomas are the most common malignant brain tumors in adults. Approximately 200000 people die each year from Glioblastoma in the world. Glioblastoma patients have a median survival of 12 months with optimal therapy and about 4 months without treatment. Glioblastomas appear as heterogeneous necrotic masses with irregular peripheral enhancement, surrounded by vasogenic edema. The current standard of care includes surgical resection, radiotherapy and chemotherapy, which require accurate segmentation of brain tumor subregions. For effective treatment planning, it is vital to identify the met…
Glioblastoma Overall Survival Prediction With Vision Transformers
Department of Electronic, Information and Bioengineering, Politecnico di Milano（电子、信息与生物工程系，米兰理工大学）；Department of Neuroradiology, Fondazione IRCCS Istituto Neurologico Carlo Besta（放射学系，IRCCS神经科学卡洛·贝斯塔研究所）
Segmentation of glioblastomas in early post-operative multi-modal MRI with deep neural networks
SINTEF Digital（SINTEF数字研究所）；Norwegian University of Science and Technology（挪威科技大学）；Amsterdam University Medical Centers（阿姆斯特丹大学医学中心）；Twee Steden Hospital（双城医院）；University College London（伦敦大学学院）
Reutlingen University（罗伊特林根大学）；Menoufia University（梅努菲亚大学）；Karlsruhe Institute of Technology（卡尔斯鲁厄理工学院）
Glioblastomas are the most aggressive fast-growing primary brain cancer which originate in the glial cells of the brain. Accurate identification of the malignant brain tumor and its sub-regions is still one of the most challenging problems in medical image segmentation. The Brain Tumor Segmentation Challenge (BraTS) has been a popular benchmark for automatic brain glioblastomas segmentation algorithms since its initiation. In this year, BraTS 2021 challenge provides the largest multi-parametric (mpMRI) dataset of 2,000 pre-operative patients. In this paper, we propose a new aggregation of two …
Decoding MGMT Methylation: A Step Towards Precision Medicine in Glioblastoma
National University of Computer and Emerging Sciences（国立计算机与新兴科学大学）；Oryx Universal College with Liverpool John Moores University（羚羊环球学院与利物浦约翰摩尔斯大学）；Al-Balqa Applied University（巴尔卡应用大学）
Future Processing Healthcare（未来医疗处理公司）；Silesian University of Technology（西里西亚工业大学）；Medical University of Silesia in Katowice（卡托维兹西里西亚医科大学）；ZSM Chorzów（霍茹夫ZSM医院）；University Clinical Centre（大学临床中心）；Roche Pharmaceutical Research & Early Development（罗氏制药研究与早期开发部）
Tumor burden assessment by magnetic resonance imaging (MRI) is central to the evaluation of treatment response for glioblastoma. This assessment is complex to perform and associated with high variability due to the high heterogeneity and complexity of the disease. In this work, we tackle this issue and propose a deep learning pipeline for the fully automated end-to-end analysis of glioblastoma patients. Our approach simultaneously identifies tumor sub-regions, including the enhancing tumor, peritumoral edema and surgical cavity in the first step, and then calculates the volumetric and bidimens…
This paper proposes to use deep radiomic features (DRFs) from a convolutional neural network (CNN) to model fine-grained texture signatures in the radiomic analysis of recurrent glioblastoma (rGBM). We use DRFs to predict survival of rGBM patients with preoperative T1-weighted post-contrast MR images (n=100). DRFs are extracted from regions of interest labelled by a radiation oncologist and used to compare between short-term and long-term survival patient groups. Random forest (RF) classification is employed to predict survival outcome (i.e., short or long survival), as well as to identify hig…
University of California at Riverside（加州大学河滨分校）；Emory University（埃默里大学）；Riverside Community Hospital（河滨社区医院）
While deep learning approaches have shown remarkable performance in many imaging tasks, most of these methods rely on availability of large quantities of data. Medical image data, however, is scarce and fragmented. Generative Adversarial Networks (GANs) have recently been very effective in handling such datasets by generating more data. If the datasets are very small, however, GANs cannot learn the data distribution properly, resulting in less diverse or low-quality results. One such limited dataset is that for the concurrent gain of 19 and 20 chromosomes (19/20 co-gain), a mutation with posit…
College of Electronic Science and Engineering, Jilin University（吉林大学电子科学与工程学院）；Wake Forest School of Medicine（维克森林医学院）
Pseudoprogression (PsP) occurs in 20-30% of patients with glioblastoma multiforme (GBM) after receiving the standard treatment. In the course of post-treatment magnetic resonance imaging (MRI), PsP exhibits similarities in shape and intensity to the true tumor progression (TTP) of GBM. So, these similarities pose challenges on the differentiation of these types of progression and hence the selection of the appropriate clinical treatment strategy. In this paper, we introduce DC-AL GAN, a novel feature learning method based on deep convolutional generative adversarial network (DCGAN) and AlexNet…
Glioblastoma Multiforme is a very aggressive type of brain tumor. Due to spatial and temporal intra-tissue inhomogeneity, location and the extent of the cancer tissue, it is difficult to detect and dissect the tumor regions. In this paper, we propose survival prognosis models using four regressors operating on handcrafted image-based and radiomics features. We hypothesize that the radiomics shape features have the highest correlation with survival prediction. The proposed approaches were assessed on the Brain Tumor Segmentation (BraTS-2020) challenge dataset. The highest accuracy of image feat…
Treatment-wise Glioblastoma Survival Inference with Multi-parametric Preoperative MRI
Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School（戈登医学影像中心，麻省总医院和哈佛医学院）；University of Southern California（南加州大学）；Yale University（耶鲁大学）
We propose a novel technique to incorporate attention within convolutional neural networks using feature maps generated by a separate convolutional autoencoder. Our attention architecture is well suited for incorporation with deep convolutional networks. We evaluate our model on benchmark segmentation datasets in skin cancer segmentation and lung lesion segmentation. Results show highly competitive performance when compared with U-Net and it's residual variant.
We present a simple and effective framework for simultaneous semantic segmentation and instance segmentation with Fully Convolutional Networks (FCNs). The method, called BiSeg, predicts instance segmentation as a posterior in Bayesian inference, where semantic segmentation is used as a prior. We extend the idea of position-sensitive score maps used in recent methods to a fusion of multiple score maps at different scales and partition modes, and adopt it as a robust likelihood for instance segmentation inference. As both Bayesian inference and map fusion are performed per pixel, BiSeg is a full…
University of Bern（伯尔尼大学）；University Hospital and University of Bern（伯尔尼大学医院和伯尔尼大学）
This paper proposes a novel approach for uncertainty quantification in dense Conditional Random Fields (CRFs). The presented approach, called Perturb-and-MPM, enables efficient, approximate sampling from dense multi-label CRFs via random perturbations. An analytic error analysis was performed which identified the main cause of approximation error as well as showed that the error is bounded. Spatial uncertainty maps can be derived from the Perturb-and-MPM model, which can be used to visualize uncertainty in image segmentation results. The method is validated on synthetic and clinical Magnetic R…
This paper summarizes our method and validation results for the ISIC Challenge 2018 - Skin Lesion Analysis Towards Melanoma Detection - Task 1: Lesion Segmentation
This paper summarizes our method and validation results for the ISBI Challenge 2017 - Skin Lesion Analysis Towards Melanoma Detection - Part I: Lesion Segmentation
In this paper, we propose a novel medical image segmentation using iterative deep learning framework. We have combined an iterative learning approach and an encoder-decoder network to improve segmentation results, which enables to precisely localize the regions of interest (ROIs) including complex shapes or detailed textures of medical images in an iterative manner. The proposed iterative deep convolutional encoder-decoder network consists of two main paths: convolutional encoder path and convolutional decoder path with iterative learning. Experimental results show that the proposed iterative …
Indian Institute of Technology Kharagpur（印度理工学院卡拉格普尔分校）
Automatic segmentation of retinal blood vessels from fundus images plays an important role in the computer aided diagnosis of retinal diseases. The task of blood vessel segmentation is challenging due to the extreme variations in morphology of the vessels against noisy background. In this paper, we formulate the segmentation task as a multi-label inference task and utilize the implicit advantages of the combination of convolutional neural networks and structured prediction. Our proposed convolutional neural network based model achieves strong performance and significantly outperforms the state…
Quantitative analysis of brain MRI at the age of 6 months is difficult because of the limited contrast between white matter and gray matter. In this study, we use a dilated triplanar convolutional neural network in combination with a non-dilated 3D convolutional neural network for the segmentation of white matter, gray matter and cerebrospinal fluid in infant brain MR images, as provided by the MICCAI grand challenge on 6-month infant brain MRI segmentation.
Tsinghua University（清华大学）；Microsoft Research Asia（微软亚洲研究院）
We present the first fully convolutional end-to-end solution for instance-aware semantic segmentation task. It inherits all the merits of FCNs for semantic segmentation and instance mask proposal. It performs instance mask prediction and classification jointly. The underlying convolutional representation is fully shared between the two sub-tasks, as well as between all regions of interest. The proposed network is highly integrated and achieves state-of-the-art performance in both accuracy and efficiency. It wins the COCO 2016 segmentation competition by a large margin. Code would be released a…
Convolutional networks are powerful visual models that yield hierarchies of features. We show that convolutional networks by themselves, trained end-to-end, pixels-to-pixels, exceed the state-of-the-art in semantic segmentation. Our key insight is to build "fully convolutional" networks that take input of arbitrary size and produce correspondingly-sized output with efficient inference and learning. We define and detail the space of fully convolutional networks, explain their application to spatially dense prediction tasks, and draw connections to prior models. We adapt contemporary classificat…
Raidionics: an open software for pre- and postoperative central nervous system tumor segmentation and standardized reporting
SINTEF Digital（挪威科技工业研究院数字分院）；Norwegian University of Science and Technology (NTNU)（挪威科技大学（NTNU））；St. Olavs hospital, Trondheim University Hospital（特隆赫姆大学医院圣奥拉夫斯医院）
Image segmentation is an important step in most visual tasks. While convolutional neural networks have shown to perform well on single image segmentation, to our knowledge, no study has been been done on leveraging recurrent gated architectures for video segmentation. Accordingly, we propose a novel method for online segmentation of video sequences that incorporates temporal data. The network is built from fully convolutional element and recurrent unit that works on a sliding window over the temporal data. We also introduce a novel convolutional gated recurrent unit that preserves the spatial …
Convolutional networks are powerful visual models that yield hierarchies of features. We show that convolutional networks by themselves, trained end-to-end, pixels-to-pixels, improve on the previous best result in semantic segmentation. Our key insight is to build "fully convolutional" networks that take input of arbitrary size and produce correspondingly-sized output with efficient inference and learning. We define and detail the space of fully convolutional networks, explain their application to spatially dense prediction tasks, and draw connections to prior models. We adapt contemporary cla…
In this work, we propose a multi-modal Convolutional Neural Network (CNN) approach for brain tumor segmentation. We investigate how to combine different modalities efficiently in the CNN framework.We adapt various fusion methods, which are previously employed on video recognition problem, to the brain tumor segmentation problem,and we investigate their efficiency in terms of memory and performance.Our experiments, which are performed on BRATS dataset, lead us to the conclusion that learning separate representations for each modality and combining them for brain tumor segmentation could increas…
Medical imaging based prostate cancer diagnosis procedure uses intra-operative transrectal ultrasound (TRUS) imaging to visualize the prostate shape and location to collect tissue samples. Correct tissue sampling from prostate requires accurate prostate segmentation in TRUS images. To achieve this, this study uses a novel residual connection based fully convolutional network. The advantage of this segmentation technique is that it requires no pre-processing of TRUS images to perform the segmentation. Thus, it offers a faster and straightforward prostate segmentation from TRUS images. Results s…
Segmentation of mandibles in CT scans during virtual surgical planning is crucial for 3D surgical planning in order to obtain a detailed surface representation of the patients bone. Automatic segmentation of mandibles in CT scans is a challenging task due to large variation in their shape and size between individuals. In order to address this challenge we propose a convolutional neural network approach for mandible segmentation in CT scans by considering the continuum of anatomical structures through different planes. The proposed convolutional neural network adopts the architecture of the U-N…
In the isointense stage, the accurate volumetric image segmentation is a challenging task due to the low contrast between tissues. In this paper, we propose a novel very deep network architecture based on a densely convolutional network for volumetric brain segmentation. The proposed network architecture provides a dense connection between layers that aims to improve the information flow in the network. By concatenating features map of fine and coarse dense blocks, it allows capturing multi-scale contextual information. Experimental results demonstrate significant advantages of the proposed me…
Isfahan University of Technology（伊斯法罕理工大学）；University of British Columbia（不列颠哥伦比亚大学）；University of Michigan（密歇根大学）；McMaster University（麦克马斯特大学）
One of the essential tasks in medical image analysis is segmentation and accurate detection of borders. Lesion segmentation in skin images is an essential step in the computerized detection of skin cancer. However, many of the state-of-the-art segmentation methods have deficiencies in their border detection phase. In this paper, a new class of fully convolutional network is proposed, with new dense pooling layers for segmentation of lesion regions in skin images. This network leads to highly accurate segmentation of lesions on skin lesion datasets which outperforms state-of-the-art algorithms …
In the last decade, deep learning has contributed to advances in a wide range computer vision tasks including texture analysis. This paper explores a new approach for texture segmentation using deep convolutional neural networks, sharing important ideas with classic filter bank based texture segmentation methods. Several methods are developed to train Fully Convolutional Networks to segment textures in various applications. We show in particular that these networks can learn to recognize and segment a type of texture, e.g. wood and grass from texture recognition datasets (no training segmentat…
Department of Computer Science（计算机科学系）；University of Saskatchewan, Canada（萨斯喀彻温大学）
In this paper, we propose an efficient architecture for semantic image segmentation using the depth-to-space (D2S) operation. Our D2S model is comprised of a standard CNN encoder followed by a depth-to-space reordering of the final convolutional feature maps. Our approach eliminates the decoder portion of traditional encoder-decoder segmentation models and reduces the amount of computation almost by half. As a participant of the DeepGlobe Road Extraction competition, we evaluate our models on the corresponding road segmentation dataset. Our highly efficient D2S models exhibit comparable perfor…
CISPA Helmholtz Center for Information Security（CISPA 亥姆霍兹信息安全中心）；Max Planck Institute for Informatics（马克斯·普朗克信息学研究所）
Recently, learning-based image synthesis has enabled to generate high-resolution images, either applying popular adversarial training or a powerful perceptual loss. However, it remains challenging to successfully leverage synthetic data for improving semantic segmentation with additional synthetic images. Therefore, we suggest to generate intermediate convolutional features and propose the first synthesis approach that is catered to such intermediate convolutional features. This allows us to generate new features from label masks and include them successfully into the training procedure in ord…
Recent leading approaches to semantic segmentation rely on deep convolutional networks trained with human-annotated, pixel-level segmentation masks. Such pixel-accurate supervision demands expensive labeling effort and limits the performance of deep networks that usually benefit from more training data. In this paper, we propose a method that achieves competitive accuracy but only requires easily obtained bounding box annotations. The basic idea is to iterate between automatically generating region proposals and training convolutional networks. These two steps gradually recover segmentation ma…
Semantic segmentation has recently witnessed major progress, where fully convolutional neural networks have shown to perform well. However, most of the previous work focused on improving single image segmentation. To our knowledge, no prior work has made use of temporal video information in a recurrent network. In this paper, we introduce a novel approach to implicitly utilize temporal data in videos for online semantic segmentation. The method relies on a fully convolutional network that is embedded into a gated recurrent architecture. This design receives a sequence of consecutive video fram…
We introduce an accurate lung segmentation model for chest radiographs based on deep convolutional neural networks. Our model is based on atrous convolutional layers to increase the field-of-view of filters efficiently. To improve segmentation performances further, we also propose a multi-stage training strategy, network-wise training, which the current stage network is fed with both input images and the outputs from pre-stage network. It is shown that this strategy has an ability to reduce falsely predicted labels and produce smooth boundaries of lung fields. We evaluate the proposed model on…
Facebook AI Research（Facebook人工智能研究院）；University of Oxford（牛津大学）
Convolutional networks are the de-facto standard for analyzing spatio-temporal data such as images, videos, and 3D shapes. Whilst some of this data is naturally dense (e.g., photos), many other data sources are inherently sparse. Examples include 3D point clouds that were obtained using a LiDAR scanner or RGB-D camera. Standard "dense" implementations of convolutional networks are very inefficient when applied on such sparse data. We introduce new sparse convolutional operations that are designed to process spatially-sparse data more efficiently, and use them to develop spatially-sparse convol…
Semantic segmentation is an important preliminary step towards automatic medical image interpretation. Recently deep convolutional neural networks have become the first choice for the task of pixel-wise class prediction. While incorporating prior knowledge about the structure of target objects has proven effective in traditional energy-based segmentation approaches, there has not been a clear way for encoding prior knowledge into deep learning frameworks. In this work, we propose a new loss term that encodes the star shape prior into the loss function of an end-to-end trainable fully convoluti…
We introduce a novel approach for temporal activity segmentation with timestamp supervision. Our main contribution is a graph convolutional network, which is learned in an end-to-end manner to exploit both frame features and connections between neighboring frames to generate dense framewise labels from sparse timestamp labels. The generated dense framewise labels can then be used to train the segmentation model. In addition, we propose a framework for alternating learning of both the segmentation model and the graph convolutional model, which first initializes and then iteratively refines the …
Télécom Paris - Institut Polytechnique de Paris（巴黎理工学院巴黎电信学院）；Università di Napoli Parthenope（那不勒斯帕泰诺佩大学）；La Rochelle Université（拉罗谢尔大学）
Semantic segmentation is a fundamental topic in computer vision. Several deep learning methods have been proposed for semantic segmentation with outstanding results. However, these models require a lot of densely annotated images. To address this problem, we propose a new algorithm that uses HyperGraph Convolutional Networks for Weakly-supervised Semantic Segmentation (HyperGCN-WSS). Our algorithm constructs spatial and k-Nearest Neighbor (k-NN) graphs from the images in the dataset to generate the hypergraphs. Then, we train a specialized HyperGraph Convolutional Network (HyperGCN) architectu…
Automatic segmentation of medical images is among most demanded works in the medical information field since it saves time of the experts in the field and avoids human error factors. In this work, a method based on Conditional Adversarial Networks and Fully Convolutional Networks is proposed for the automatic segmentation of the liver MRIs. The proposed method, without any post-processing, is achieved the second place in the SIU Liver Segmentation Challenge 2018, data of which is provided by Dokuz Eylül University. In this paper, some improvements for the post-processing step are also proposed…
University of Science and Technology of China（中国科学技术大学）；Tsinghua University（清华大学）；The Hong Kong University of Science and Technology（香港科技大学）
This paper proposes a convolutional neural network that can fuse high-level prior for semantic image segmentation. Motivated by humans' vision recognition system, our key design is a three-layer generative structure consisting of high-level coding, middle-level segmentation and low-level image to introduce global prior for semantic segmentation. Based on this structure, we proposed a generative model called conditional variational auto-encoder (CVAE) that can build up the links behind these three layers. These important links include an image encoder that extracts high level info from image, a…
Deep learning (DL) based semantic segmentation methods have been providing state-of-the-art performance in the last few years. More specifically, these techniques have been successfully applied to medical image classification, segmentation, and detection tasks. One deep learning technique, U-Net, has become one of the most popular for these applications. In this paper, we propose a Recurrent Convolutional Neural Network (RCNN) based on U-Net as well as a Recurrent Residual Convolutional Neural Network (RRCNN) based on U-Net models, which are named RU-Net and R2U-Net respectively. The proposed …
Northwestern Polytechnical University（西北工业大学）；University of Sydney（悉尼大学）；University of Pittsburgh（匹兹堡大学）；Royal Prince Alfred Hospital（皇家阿尔弗雷德亲王医院）
Advanced deep learning methods have been developed to conduct prostate MR volume segmentation in either a 2D or 3D fully convolutional manner. However, 2D methods tend to have limited segmentation performance, since large amounts of spatial information of prostate volumes are discarded during the slice-by-slice segmentation process; and 3D methods also have room for improvement, since they use isotropic kernels to perform 3D convolutions whereas most prostate MR volumes have anisotropic spatial resolution. Besides, the fully convolutional structural methods achieve good performance for localiz…
Many research works focus on leveraging the complementary geometric information of indoor depth sensors in vision tasks performed by deep convolutional neural networks, notably semantic segmentation. These works deal with a specific vision task known as "RGB-D Indoor Semantic Segmentation". The challenges and resulting solutions of this task differ from its standard RGB counterpart. This results in a new active research topic. The objective of this paper is to introduce the field of Deep Convolutional Neural Networks for RGB-D Indoor Semantic Segmentation. This review presents the most popular…
We propose a novel weakly-supervised semantic segmentation algorithm based on Deep Convolutional Neural Network (DCNN). Contrary to existing weakly-supervised approaches, our algorithm exploits auxiliary segmentation annotations available for different categories to guide segmentations on images with only image-level class labels. To make the segmentation knowledge transferrable across categories, we design a decoupled encoder-decoder architecture with attention model. In this architecture, the model generates spatial highlights of each category presented in an image using an attention model, …
Remote Sensing Technology Institute (IMF), German Aerospace Center (DLR)（德国航空航天中心（DLR）遥感技术研究所（IMF））；Signal Processing in Earth Observation (SiPEO), Technical University of Munich (TUM)（慕尼黑工业大学（TUM）地球观测信号处理（SiPEO））
Semantic segmentation in high resolution remote sensing images is a fundamental and challenging task. Convolutional neural networks (CNNs), such as fully convolutional network (FCN) and SegNet, have shown outstanding performance in many segmentation tasks. One key pillar of these successes is mining useful information from features in convolutional layers for producing high resolution segmentation maps. For example, FCN nonlinearly combines high-level features extracted from last convolutional layers; whereas SegNet utilizes a deconvolutional network which takes as input only coarse, high-leve…
Technische Universität München（慕尼黑工业大学）；Ludwig-Maximilians-University（路德维希-马克西米利安大学）；Indian Institute of Technology Kharagpur（印度理工学院克勒格布尔分校）；Johns Hopkins University（约翰斯·霍普金斯大学）
Optical coherence tomography (OCT) is used for non-invasive diagnosis of diabetic macular edema assessing the retinal layers. In this paper, we propose a new fully convolutional deep architecture, termed ReLayNet, for end-to-end segmentation of retinal layers and fluid masses in eye OCT scans. ReLayNet uses a contracting path of convolutional blocks (encoders) to learn a hierarchy of contextual features, followed by an expansive path of convolutional blocks (decoders) for semantic segmentation. ReLayNet is trained to optimize a joint loss function comprising of weighted logistic regression and…
We consider the problem of segmenting a biomedical image into anatomical regions of interest. We specifically address the frequent scenario where we have no paired training data that contains images and their manual segmentations. Instead, we employ unpaired segmentation images to build an anatomical prior. Critically these segmentations can be derived from imaging data from a different dataset and imaging modality than the current task. We introduce a generative probabilistic model that employs the learned prior through a convolutional neural network to compute segmentations in an unsupervise…
Ben-Gurion University（本-古里安大学）；The Kreitman School of Advanced Graduate Studies（克雷特曼高级研究生学院）
Live cell microscopy sequences exhibit complex spatial structures and complicated temporal behaviour, making their analysis a challenging task. Considering cell segmentation problem, which plays a significant role in the analysis, the spatial properties of the data can be captured using Convolutional Neural Networks (CNNs). Recent approaches show promising segmentation results using convolutional encoder-decoders such as the U-Net. Nevertheless, these methods are limited by their inability to incorporate temporal information, that can facilitate segmentation of individual touching cells or of …
