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arXiv 0907.3215cs.CV
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组织图像的全自动3D重建

Fully Automatic 3D Reconstruction of Histological Images

The University of Nottingham(诺丁汉大学)

Ulas Bagci, Li Bai

摘要:

在本文中,我们提出了一个计算框架,从2D组织切片的3D体积重建使用注册算法在特征空间。为了提高重建的3D体积的质量,首先,通过强度标准化过程来校正图像中的强度变化,该强度标准化过程将图像强度标度映射到标准标度,其中相似的强度对应于相似的组织。其次,提出了一种子体积方法,通过划分标准化切片成组的三维重建。第三,为了提高重建过程的质量,一个自动的最佳参考层选择算法的基础上迭代评估图像熵和均方误差的配准过程。最后,我们证明了参考切片的选择对配准质量和随后的3D重建有显着的影响。

英文摘要:

In this paper, we propose a computational framework for 3D volume reconstruction from 2D histological slices using registration algorithms in feature space. To improve the quality of reconstructed 3D volume, first, intensity variations in images are corrected by an intensity standardization process which maps image intensity scale to a standard scale where similar intensities correspond to similar tissues. Second, a subvolume approach is proposed for 3D reconstruction by dividing standardized slices into groups. Third, in order to improve the quality of the reconstruction process, an automatic best reference slice selection algorithm is developed based on an iterative assessment of image entropy and mean square error of the registration process. Finally, we demonstrate that the choice of the reference slice has a significant impact on registration quality and subsequent 3D reconstruction.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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