基因组进化和生长的极小模型
Minimal model for genome evolution and growth
摘要:
对典型微生物基因组的文本分析表明,它们具有长度短得多的DNA序列的统计特征。这种特殊的性质支持了一种进化模型,即基因组通过随机突变进化,但主要是通过随机片段自我复制生长。基因组主要通过自我复制增长,这与所有基因组中的重复序列普遍存在,基因组内和基因组间同源基因在所有生命形式中占优势的观察结果一致。该模型预言了两种相互竞争的进化模式的共存:经典达尔文主义的渐进变化和“间断平衡”中设想的随机爆发。
英文摘要:
Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random mutation but primarily grows by random segmental self-copying. That genomes grew mostly by self-copying is consistent with the observation that repeat sequences in all genomes are widespread and intragenomic and intergenomic homologous genes are preponderance across all life forms. The model predicates the coexistence of the two competing modes of evolution: the gradual changes of classical Darwinism and the stochastic spurts envisioned in ``punctuated equilibrium''.
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