Large language models (LLMs) are increasingly used as decision-support tools in data-constrained scientific workflows, where correctness and validity are critical. However, evaluation practices often emphasize stability or reproducibility across repeated runs. While these properties are desirable, stability alone does not guar- antee agreement with statistical ground truth when such references are available. We introduce a controlled behavioral evaluation framework that explicitly sep- arates four dimensions of LLM decision-making: stability, correctness, prompt sensitivity, and output validity under fixed statistical inputs. We evaluate multi- ple LLMs using a statistical gene prioritization task derived from differential ex- pression analysis across prompt regimes involving strict and relaxed significance thresholds, borderline ranking scenarios, and minor wording variations. Our ex- periments show that LLMs can exhibit near-perfect run-to-run stability while sys- tematically diverging from statistical ground truth, over-selecting under relaxed thresholds, responding sharply to minor prompt wording changes, or producing syntactically plausible gene identifiers absent from the input table. Although sta- bility reflects robustness across repeated runs, it does not guarantee agreement with statistical ground truth in structured scientific decision tasks. These findings highlight the importance of explicit ground-truth validation and output validity checks when deploying LLMs in automated or semi-automated scientific work- flows.
Induced Numerical Instability: Hidden Costs in Multimodal Large Language Models
School of Computing(计算学院);Information Systems, Singapore Management University, Singapore(信息系统,新加坡管理大学,新加坡);Information Systems Department, Rutgers Business School, New Jersey, USA(信息系统系,罗格斯商学院,新泽西,美国)
CausalGame: Benchmarking Causal Thinking of LLM Agents in Games
MBZUAI(穆罕默德·本·扎耶德人工智能大学);Carnegie Mellon University(卡内基梅隆大学);Hong Kong Baptist University(香港浸会大学);University of Oxford(牛津大学);New York University, Abu Dhabi(纽约大学阿布扎比分校)
Benchmark Illusion: Disagreement among LLMs and Its Scientific Consequences
Department of Political Science, Purdue University(政治学系,普渡大学);Kellogg School of Management, Center for Science of Science and Innovation, Northwestern Innovation Institute, Ryan Institute on Complexity, and McCormick School of Engineering(凯洛格管理学院、科学与创新中心、西北创新研究所、复杂性研究院以及麦科马克工程学院)
Systematic Failures in Collective Reasoning under Distributed Information in Multi-Agent LLMs
School of Computer Science, Carnegie Mellon University, Pittsburgh, USA(计算机科学学院,卡内基梅隆大学,匹兹堡,美国);School of Environment and Society, Institute of Science Tokyo, Tokyo, Japan(环境与社会学院,东京科学研究所,东京,日本)
From Weak Task Specifications to Scientific Extraction Agents: Optimizing Task Construction
University of Science and Technology of China(中国科学技术大学);State Key Laboratory of Cognitive Intelligence(认知智能全国重点实验室);CCCC Second Highway Consultants Co., Ltd.(中交第二公路勘察设计研究院有限公司)
Encoded but Not Routed: Explaining the Table-Chart Gap in Scientific Claim Verification
The University of Tokyo(东京大学);NII LLMC(日本信息处理学会LLMC);National Institute of Informatics(日本信息处理研究所);University of Göttingen(哥廷根大学);Inria, LS2N, Nantes Université(法国国家信息与自动化技术研究院(Inria)、LS2N实验室、南特大学)
Demystifying Scientific Problem-Solving in LLMs by Probing Knowledge and Reasoning
Department of Computer Science, Yale University;Department of Molecular \& Cellular Biology, Harvard University;Allen Institute for AI;Department of Computer Science, Northwestern University
SciIF: Benchmarking Scientific Instruction Following Towards Rigorous Scientific Intelligence
Shanghai AI Laboratory(上海人工智能实验室);University of Science and Technology of China(中国科学技术大学);Shanghai Jiao Tong University(上海交通大学);The Chinese University of Hong Kong(香港中文大学);University of Sydney(悉尼大学);Fudan University(复旦大学);Tsinghua University(清华大学);Beihang University(北航大学)
A quantum learning approach based on Hidden Markov Models for failure scenarios generation
EDF Lab Saclay(法国电力公司萨克莱实验室);LIPN - CNRS UMR 7030(法国国家科学研究中心LIPN实验室(UMR 7030));Université Sorbonne Paris Nord(索邦巴黎北大学);La Maison des Sciences Numériques(数字科学之家)
Scientifically-Interpretable Reasoning Network (ScIReN): Discovering Hidden Relationships in the Carbon Cycle and Beyond
Department of Informatics and Intelligent Systems, Institute of Energy and the Environment, The Pennsylvania State University(信息学与智能系统系,能源与环境研究所,宾夕法尼亚州立大学)
FLAT: Revealing Hidden Latent-Conditioned Backdoor Failures in Federated Learning
College of Engineering and Computer Science, VinUniversity(VinUniversity工程与计算机科学学院);VinUni-Illinois Smart Health Center, VinUniversity(VinUniversity-VinUni-Illinois智能健康中心);Siebel School of Computing and Data Science, University of Illinois Urbana-Champaign(伊利诺伊大学厄巴纳-香槟分校Siebel计算与数据科学学院);Faculty of Computer Science and Information Technology, Universiti Malaya(马来亚大学计算机科学与信息技术学院)
Uncertainties in Physics-informed Inverse Problems: The Hidden Risk in Scientific AI
Graduate School of Social and Data Sciences(社会科学与数据科学研究生院);Hitotsubashi University(立命馆大学);Department of Electrical and Electronic Engineering(电子工程系);Nihon University(日立大学)
When Molecular Similarity Works: Property Cliffs Reveal Hidden Errors
School of Economics and Management(经济管理学院);School of Computer Science(计算机科学学院);Department of Data Science and Artificial Intelligence(数据科学与人工智能系);College of Computer Science and Technology(计算机科学与技术学院);School of Life Sciences and Technology(生命科学与技术学院)