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arXiv 2602.09219math.STstat.TH

非线性逆问题中随机观测的拟合性检验

Goodness-of-fit testing for nonlinear inverse problems with random observations

Remo Kretschmann, Han Cheng Lie

AI总结:

本文提出了一种非线性逆问题中随机观测的拟合性检验方法,通过后验收缩速率分析,建立了区分备择假设与原假设的能力,并应用于药代动力学中的常微分方程问题。

摘要:

本文关注非参数拟合性检验在非线性逆问题中的应用,其中观测数据是随机的。基于高斯过程先验分布的贝叶斯后验分布被证明在一定速率下均匀收缩于一组真实参数集上。相应的后验均值被证明在后验收缩速率下均匀收敛,满足集中不等式。通过基于后验均值和最大后验估计量的极小插值检验,建立了在后验收缩速率下区分有界备择假设与复合原假设的能力。这些结果应用于由常微分方程初值问题所支配的一类逆问题,这类问题在药代动力学中广泛应用。对于此类问题,证明了均匀后验收缩速率,并利用其建立区分性。

英文摘要:

This work is concerned with nonparametric goodness-of-fit testing in the context of nonlinear inverse problems with random observations. Bayesian posterior distributions based upon a Gaussian process prior distribution are proven to contract at a certain rate uniformly over a set of true parameters. The corresponding posterior mean is shown to converge uniformly at the posterior contraction rate in the sense of satisfying a concentration inequality. Distinguishability for bounded alternatives separated from a composite null hypothesis at the posterior contraction rate is established using infimum plug-in tests based on the posterior mean and also on maximum a posteriori estimators. The results are applied to a class of inverse problems governed by ordinary differential equation initial value problems that is widely used in pharmacokinetics. For this class, uniform posterior contraction rates are proven and then used to establish distinguishability.

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