BrainSegDMlF: A Dynamic Fusion-enhanced SAM for Brain Lesion Segmentation
Southern University of Science and Technology(南方科技大学);Jarvis Research Center, Tencent YouTu Lab(腾讯优图实验室);Westlake University(西湖大学);Shenzhen University of Advanced Technology(深圳先进技术大学);Tencent YouTu Lab(腾讯优图实验室);Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences(深圳先进技术研究所,中国科学院)
The segmentation of substantial brain lesions is a significant and challenging task in the field of medical image segmentation. Substantial brain lesions in brain imaging exhibit high heterogeneity, with indistinct boundaries between lesion regions and normal brain tissue. Small lesions in single slices are difficult to identify, making the accurate and reproducible segmentation of abnormal regions, as well as their feature description, highly complex. Existing methods have the following limitations: 1) They rely solely on single-modal information for learning, neglecting the multi-modal information commonly used in diagnosis. This hampers the ability to comprehensively acquire brain lesion information from multiple perspectives and prevents the effective integration and utilization of multi-modal data inputs, thereby limiting a holistic understanding of lesions. 2) They are constrained by the amount of data available, leading to low sensitivity to small lesions and difficulty in detecting subtle pathological changes. 3) Current SAM-based models rely on external prompts, which cannot achieve automatic segmentation and, to some extent, affect diagnostic efficiency.To address these issues, we have developed a large-scale fully automated segmentation model specifically designed for brain lesion segmentation, named BrainSegDMLF. This model has the following features: 1) Dynamic Modal Interactive Fusion (DMIF) module that processes and integrates multi-modal data during the encoding process, providing the SAM encoder with more comprehensive modal information. 2) Layer-by-Layer Upsampling Decoder, enabling the model to extract rich low-level and high-level features even with limited data, thereby detecting the presence of small lesions. 3) Automatic segmentation masks, allowing the model to generate lesion masks automatically without requiring manual prompts.
{S$^3$-Mamba}: Small-Size-Sensitive Mamba for Lesion Segmentation
Shenzhen University(深圳大学);University of Nottingham Ningbo China(宁波诺丁汉大学);Guangxi Medical University(广西医科大学);City University of Hong Kong(香港城市大学);University of Nottingham(诺丁汉大学)
University of Chinese Academy of Sciences(中国科学院大学)
Weakly-supervised learning under image-level labels supervision has been widely applied to semantic segmentation of medical lesions regions. However, 1) most existing models rely on effective constraints to explore the internal representation of lesions, which only produces inaccurate and coarse lesions regions; 2) they ignore the strong probabilistic dependencies between target lesions dataset (e.g., enteroscopy images) and well-to-annotated source diseases dataset (e.g., gastroscope images). To better utilize these dependencies, we present a new semantic lesions representation transfer model…
Multi-Sequence Parotid Gland Lesion Segmentation via Expert Text-Guided Segment Anything Model
Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University(中山大学附属第一医院放射科);Department of Radiology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center(中山大学南方学院肿瘤学国家重点实验室、癌症医学创新中心、中山大学肿瘤中心放射科);Department of Radiology, Shantou Central Hospital(汕头市中心医院放射科);Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University(广东省恶性肿瘤表观遗传学与基因调控重点实验室、中山大学附属第一医院医学研究中心、中山大学);Department of Radiology, Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University(中山大学附属山田医院放射科)
The success of supervised lesion segmentation algorithms using Computed Tomography (CT) exams depends significantly on the quantity and variability of samples available for training. While annotating such data constitutes a challenge itself, the variability of lesions in the dataset also depends on the prevalence of different types of lesions. This phenomenon adds an inherent bias to lesion segmentation algorithms that can be diminished, among different possibilities, using aggressive data augmentation methods. In this paper, we present a method for implanting realistic lesions in CT slices to…
NVIDIA AI Technology Center(英伟达人工智能技术中心);Nanyang Technological University(南洋理工大学);Monash University(莫纳什大学)
Lesion detection from computed tomography (CT) scans is challenging compared to natural object detection because of two major reasons: small lesion size and small inter-class variation. Firstly, the lesions usually only occupy a small region in the CT image. The feature of such small region may not be able to provide sufficient information due to its limited spatial feature resolution. Secondly, in CT scans, the lesions are often indistinguishable from the background since the lesion and non-lesion areas may have very similar appearances. To tackle both problems, we need to enrich the feature …
Universitat Pompeu Fabra(庞培法布拉大学);University of Adelaide(阿德莱德大学);Catalan Institution for Research and Advanced Studies (ICREA)(加泰罗尼亚研究与高级研究所(ICREA))
We study the impact of different loss functions on lesion segmentation from medical images. Although the Cross-Entropy (CE) loss is the most popular option when dealing with natural images, for biomedical image segmentation the soft Dice loss is often preferred due to its ability to handle imbalanced scenarios. On the other hand, the combination of both functions has also been successfully applied in this kind of tasks. A much less studied problem is the generalization ability of all these losses in the presence of Out-of-Distribution (OoD) data. This refers to samples appearing in test time t…
Mask-Enhanced Segment Anything Model for Tumor Lesion Semantic Segmentation
Beihang University(北京航空航天大学);Hangzhou Innovation Institute, Beihang University(北京航空航天大学杭州创新研究院);Institute of Information Engineering, Chinese Academy of Sciences(中国科学院信息工程研究所);The Chinese University of Hong Kong(香港中文大学);Sun Yat-sen University(中山大学);Peking University Cancer Hospital & Institute(北京大学肿瘤医院暨研究所);Nanjing University(南京大学)
Monitoring the progression of lesions is important for clinical response. Summary statistics such as lesion volume are objective and easy to interpret, which can help clinicians assess lesion growth or decay. CNNs are commonly used in medical image segmentation for their ability to produce useful features within large contexts and their associated efficient iterative patch-based training. Many CNN architectures require hundreds of thousands parameters to yield a good segmentation. In this work, an efficient, computationally inexpensive CNN is implemented to estimate the number of lesion voxels…
Tsinghua University(清华大学);Huazhong University of Science and Technology(华中科技大学)
Segmentation of infected areas in chest CT volumes is of great significance for further diagnosis and treatment of COVID-19 patients. Due to the complex shapes and varied appearances of lesions, a large number of voxel-level labeled samples are generally required to train a lesion segmentation network, which is a main bottleneck for developing deep learning based medical image segmentation algorithms. In this paper, we propose a weakly-supervised lesion segmentation framework by embedding the Generative Adversarial training process into the Segmentation Network, which is called GASNet. GASNet …
Ischemic Stroke Lesion Segmentation challenge (ISLES 2022) offers a platform for researchers to compare their solutions to 3D segmentation of ischemic stroke regions from 3D MRIs. In this work, we describe our solution to ISLES 2022 segmentation task. We re-sample all images to a common resolution, use two input MRI modalities (DWI and ADC) and train SegResNet semantic segmentation network from MONAI. The final submission is an ensemble of 15 models (from 3 runs of 5-fold cross validation). Our solution (team name NVAUTO) achieves the top place in terms of Dice metric (0.824), and overall rank…
We present Spectral GUI, a multiplatform breast MR image analysis tool designed to facilitate the segmentation of fibro glandular tissues and lesions in T1 weighted breast MR images via a graphical user interface (GUI). Spectral GUIR uses spectrum loft method [1] for breast MR image segmentation. Not only is it interactive, but robust and expeditious at the same time. Being devoid of any machine learning algorithm, it shows exceptionally high execution speed with minimal overheads. The accuracy of the results has been simultaneously measured using performance metrics and expert entailment. The…
Tarbiat Modares University(塔比亚特莫达雷斯大学);Islamic Azad University Science and Research Branch(伊斯兰阿扎德大学科学与研究分校)
At present, cancer is one of the most important health issues in the world. Because early detection and appropriate treatment in cancer are very effective in the recovery and survival of patients, image processing as a diagnostic tool can help doctors to diagnose in the first recognition of cancer. One of the most important steps in diagnosing a skin lesion is to automatically detect the border of the skin image because the accuracy of the next steps depends on it. If these subtleties are identified, they can have a great impact on the diagnosis of the disease. Therefore, there is a good oppor…
Early detection of melanoma is difficult for the human eye but a crucial step towards reducing its death rate. Computerized detection of these melanoma and other skin lesions is necessary. The central research question in this paper is "How to segment skin lesion images using a neural network with low available data?". This question is divided into three sub questions regarding best performing network structure, training data and training method. First theory associated with these questions is discussed. Literature states that U-net CNN structures have excellent performances on the segmentatio…
Institute for Infocomm Research (I2R), Agency for Science, Technology and Research (A*STAR)(新加坡科技研究局(A*STAR)资讯通信研究院(I2R));Nanyang Technological University(南洋理工大学);National University of Singapore(新加坡国立大学)
Label scarcity has been a long-standing issue for biomedical image segmentation, due to high annotation costs and professional requirements. Recently, active learning (AL) strategies strive to reduce annotation costs by querying a small portion of data for annotation, receiving much traction in the field of medical imaging. However, most of the existing AL methods have to initialize models with some randomly selected samples followed by active selection based on various criteria, such as uncertainty and diversity. Such random-start initialization methods inevitably introduce under-value redund…
National Taiwan University(台湾大学);Santa Clara University(圣克拉拉大学);QNAP Systems, Inc(威联通科技股份有限公司);Taipei Hospital(台北医院);National Taiwan University Hospital(台湾大学附属医院)
Semantic segmentation of medical images with deep learning models is rapidly developed. In this study, we benchmarked state-of-the-art deep learning segmentation algorithms on our clinical stereotactic radiosurgery dataset, demonstrating the strengths and weaknesses of these algorithms in a fairly practical scenario. In particular, we compared the model performances with respect to their sampling method, model architecture, and the choice of loss functions, identifying the suitable settings for their applications and shedding light on the possible improvements.
Warren Alpert Medical School of Brown University(布朗大学沃伦·阿尔珀特医学院);Emory University School of Medicine(埃默里大学医学院);University of Florida School of Medicine(佛罗里达大学医学院);Brown University(布朗大学)
Automated segmentation of medical imaging is of broad interest to clinicians and machine learning researchers alike. The goal of segmentation is to increase efficiency and simplicity of visualization and quantification of regions of interest within a medical image. Image segmentation is a difficult task because of multiparametric heterogeneity within the images, an obstacle that has proven especially challenging in efforts to automate the segmentation of brain lesions from non-contrast head computed tomography (CT). In this research, we have experimented with multiple available deep learning a…
Segmenting skin lesions images is relevant both for itself and for assisting in lesion classification, but suffers from the challenge in obtaining annotated data. In this work, we show that segmentation may improve with less data, by selecting the training samples with best inter-annotator agreement, and conditioning the ground-truth masks to remove excessive detail. We perform an exhaustive experimental design considering several sources of variation, including three different test sets, two different deep-learning architectures, and several replications, for a total of 540 experimental runs.…
Institute of High Performance Computing, A*STAR(新加坡科技研究局高性能计算研究所);Institute for Infocomm Research, A*STAR(新加坡科技研究局资讯通信研究院);National Skin Center, National Healthcare Group(国立皮肤中心,国立保健集团)
In this study, a multi-task deep neural network is proposed for skin lesion analysis. The proposed multi-task learning model solves different tasks (e.g., lesion segmentation and two independent binary lesion classifications) at the same time by exploiting commonalities and differences across tasks. This results in improved learning efficiency and potential prediction accuracy for the task-specific models, when compared to training the individual models separately. The proposed multi-task deep learning model is trained and evaluated on the dermoscopic image sets from the International Skin Ima…
CenterMamba-SAM: Center-Prioritized Scanning and Temporal Prototypes for Brain Lesion Segmentation
Northeastern University, Boston, United States(东北大学);Stevens Institute of Technology, Hoboken, United States(史蒂文斯理工学院);Rutgers University, Newark, United States(罗格斯大学);Lehigh University, Bethlehem, United States(莱恩大学);University of the Cumberlands, Williamsburg, United States(坎伯兰大学)
TP-DRSeg: Improving Diabetic Retinopathy Lesion Segmentation with Explicit Text-Prompts Assisted SAM
Monash-Airdoc Research(莫纳什-鹰瞳研究中心);Monash University(莫纳什大学);Monash Medical AI Group(莫纳什医学人工智能集团);School of Computer Science and Engineering, Sun Yat-sen University(中山大学计算机科学与工程学院)
Ohio University(俄亥俄大学);University of Kentucky(肯塔基大学)
In this paper, we develop a two-stage neural network solution for the challenging task of white-matter lesion segmentation. To cope with the vast vari- ability in lesion sizes, we sample brain MR scans with patches at three differ- ent dimensions and feed them into separate fully convolutional neural networks (FCNs). In the second stage, we process large and small lesion separately, and use ensemble-nets to combine the segmentation results generated from the FCNs. A novel activation function is adopted in the ensemble-nets to improve the segmen- tation accuracy measured by Dice Similarity Coef…
Tel Aviv University(特拉维夫大学);Technion - Israel Institute of Technology(以色列理工学院)
Training data is the key component in designing algorithms for medical image analysis and in many cases it is the main bottleneck in achieving good results. Recent progress in image generation has enabled the training of neural network based solutions using synthetic data. A key factor in the generation of new samples is controlling the important appearance features and potentially being able to generate a new sample of a specific class with different variants. In this work we suggest the synthesis of new data by mixing the class specified and unspecified representation of different factors in…
SAM-Swin: SAM-Driven Dual-Swin Transformers with Adaptive Lesion Enhancement for Laryngo-Pharyngeal Tumor Detection
College of Big Data and Internet, Shenzhen Technology University(深圳技术大学大数据与互联网学院);The First Affiliated Hospital, Sun Yat-Sen University(中山大学附属第一医院);Aberdeen Institute of Data Science and Artificial Intelligence, South China Normal University(华南师范大学阿伯丁数据科学与人工智能学院)
TU Munich(慕尼黑工业大学);Johns Hopkins University(约翰斯·霍普金斯大学)
Generative Adversarial Networks (GANs) have been successfully used to synthesize realistically looking images of faces, scenery and even medical images. Unfortunately, they usually require large training datasets, which are often scarce in the medical field, and to the best of our knowledge GANs have been only applied for medical image synthesis at fairly low resolution. However, many state-of-the-art machine learning models operate on high resolution data as such data carries indispensable, valuable information. In this work, we try to generate realistically looking high resolution images of …
The identification of lesion within medical image data is necessary for diagnosis, treatment and prognosis. Segmentation and classification approaches are mainly based on supervised learning with well-paired image-level or voxel-level labels. However, labeling the lesion in medical images is laborious requiring highly specialized knowledge. We propose a medical image synthesis model named abnormal-to-normal translation generative adversarial network (ANT-GAN) to generate a normal-looking medical image based on its abnormal-looking counterpart without the need for paired training data. Unlike t…
The Chinese University of Hong Kong(香港中文大学);Imsight Medical Technology, Inc.(Imsight医疗科技公司)
Automatic skin lesion segmentation on dermoscopic images is an essential component in computer-aided diagnosis of melanoma. Recently, many fully supervised deep learning based methods have been proposed for automatic skin lesion segmentation. However, these approaches require massive pixel-wise annotation from experienced dermatologists, which is very costly and time-consuming. In this paper, we present a novel semi-supervised method for skin lesion segmentation by leveraging both labeled and unlabeled data. The network is optimized by the weighted combination of a common supervised loss for l…
In this paper, a novel approach for automatic segmentation and classification of skin lesions is proposed. Initially, skin images are filtered to remove unwanted hairs and noise and then the segmentation process is carried out to extract lesion areas. For segmentation, a region growing method is applied by automatic initialization of seed points. The segmentation performance is measured with different well known measures and the results are appreciable. Subsequently, the extracted lesion areas are represented by color and texture features. SVM and k-NN classifiers are used along with their fus…
Technical University of Munich(慕尼黑工业大学);Klinikum rechts der Isar(伊萨尔河畔临床医院);University of Dundee(邓迪大学)
Segmentation of both large and small white matter hyperintensities/lesions in brain MR images is a challenging task which has drawn much attention in recent years. We propose a multi-scale aggregation model framework to deal with volume-varied lesions. Firstly, we present a specifically-designed network for small lesion segmentation called Stack-Net, in which multiple convolutional layers are connected, aiming to preserve rich local spatial information of small lesions before the sub-sampling layer. Secondly, we aggregate multi-scale Stack-Nets with different receptive fields to learn multi-sc…
Automatic lesion segmentation in dermoscopy images is an essential step for computer-aided diagnosis of melanoma. The dermoscopy images exhibits rotational and reflectional symmetry, however, this geometric property has not been encoded in the state-of-the-art convolutional neural networks based skin lesion segmentation methods. In this paper, we present a deeply supervised rotation equivariant network for skin lesion segmentation by extending the recent group rotation equivariant network~\cite{cohen2016group}. Specifically, we propose the G-upsampling and G-projection operations to adapt the …
University of Science and Technology of China(中国科学技术大学);Institute of Computing Technology, CAS(中国科学院计算技术研究所)
Self-paced curriculum learning (SCL) has demonstrated its great potential in computer vision, natural language processing, etc. During training, it implements easy-to-hard sampling based on online estimation of data difficulty. Most SCL methods commonly adopt a loss-based strategy of estimating data difficulty and deweighting the `hard' samples in the early training stage. While achieving success in a variety of applications, SCL stills confront two challenges in a medical image analysis task, such as universal lesion detection, featuring insufficient and highly class-imbalanced data: (i) the …
Acute stroke lesion segmentation tasks are of great clinical interest as they can help doctors make better informed treatment decisions. Magnetic resonance imaging (MRI) is time demanding but can provide images that are considered gold standard for diagnosis. Automated stroke lesion segmentation can provide with an estimate of the location and volume of the lesioned tissue, which can help in the clinical practice to better assess and evaluate the risks of each treatment. We propose a deep learning methodology for acute and sub-acute stroke lesion segmentation using multimodal MR imaging. The p…
Data-driven models are now deployed in a plethora of real-world applications - including automated diagnosis - but models learned from data risk learning biases from that same data. When models learn spurious correlations not found in real-world situations, their deployment for critical tasks, such as medical decisions, can be catastrophic. In this work we address this issue for skin-lesion classification models, with two objectives: finding out what are the spurious correlations exploited by biased networks, and debiasing the models by removing such spurious correlations from them. We perform…
Lesion synthesis received much attention with the rise of efficient generative models for augmenting training data, drawing lesion evolution scenarios, or aiding expert training. The quality and diversity of synthesized data are highly dependent on the annotated data used to train the models, which not rarely struggle to derive very different yet realistic samples from the training ones. That adds an inherent bias to lesion segmentation algorithms and limits synthesizing lesion evolution scenarios efficiently. This paper presents a method for decoupling shape and density for liver lesion synth…
A Clinical-oriented Multi-level Contrastive Learning Method for Disease Diagnosis in Low-quality Medical Images
Northeastern University(东北大学);Key Laboratory of Intelligent Computing in Medical Image of Ministry of Education(医学图像智能计算教育部重点实验室);National Frontiers Science Center for Industrial Intelligence and Systems Optimization(工业智能与系统优化全国前沿科学中心)
School of Information Technology and Electrical Engineering, University of Queensland(昆士兰大学信息技术与电气工程学院);Science and Engineering Faculty, Queensland University of Technology(昆士兰科技大学科学与工程学院)
Previous studies on computer aided detection/diagnosis (CAD) in 4D breast magnetic resonance imaging (MRI) regard lesion detection, segmentation and characterization as separate tasks, and typically require users to manually select 2D MRI slices or regions of interest as the input. In this work, we present a breast MRI CAD system that can handle 4D multimodal breast MRI data, and integrate lesion detection, segmentation and characterization with no user intervention. The proposed CAD system consists of three major stages: region candidate generation, feature extraction and region candidate cla…
Adapting Segment Anything Model 3 for Concept-Driven Lesion Segmentation in Medical Images: An Experimental Study
The Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, University of Texas Southwestern Medical Center(德克萨斯大学西南医学中心放射肿瘤学系医学人工智能与自动化(MAIA)实验室);Medical Image Processing Group, Department of Radiology, University of Pennsylvania(宾夕法尼亚大学放射学系医学图像处理组);Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center(德克萨斯大学西南医学中心内科学系消化与肝脏疾病科)
University of Campinas (UNICAMP)(坎皮纳斯州立大学(UNICAMP))
Despite the growing availability of high-quality public datasets, the lack of training samples is still one of the main challenges of deep-learning for skin lesion analysis. Generative Adversarial Networks (GANs) appear as an enticing alternative to alleviate the issue, by synthesizing samples indistinguishable from real images, with a plethora of works employing them for medical applications. Nevertheless, carefully designed experiments for skin-lesion diagnosis with GAN-based data augmentation show favorable results only on out-of-distribution test sets. For GAN-based data anonymization $-$ …
Beijing Institute of Technology(北京理工大学);Peking University Third Hospital(北京大学第三医院);Deepwise AI Lab(深度智耀人工智能实验室)
Brain lesion segmentation provides a valuable tool for clinical diagnosis, and convolutional neural networks (CNNs) have achieved unprecedented success in the task. Data augmentation is a widely used strategy that improves the training of CNNs, and the design of the augmentation method for brain lesion segmentation is still an open problem. In this work, we propose a simple data augmentation approach, dubbed as CarveMix, for CNN-based brain lesion segmentation. Like other "mix"-based methods, such as Mixup and CutMix, CarveMix stochastically combines two existing labeled images to generate new…
Morphology-Enhanced CAM-Guided SAM for weakly supervised Breast Lesion Segmentation
Beijing University of Technology(北京工业大学);KTH Royal Institute of Technology(瑞典皇家理工学院);Institut du Cerveau – Paris Brain Institute - ICM(巴黎脑研究所);CNRS(法国国家科学研究中心);Inria(法国国家信息与自动化研究所);Inserm(法国国家健康与医学研究院);AP-HP(巴黎公立医院集团)
Istituto Italiano di Tecnologia(意大利理工学院);University of Genoa(热那亚大学);Fondation Campus Biotech Geneva(日内瓦校园生物技术基金会);San Raffaele Scientific Institute(圣拉斐尔科学研究所);University of Verona(维罗纳大学);Fondazione Bruno Kessler(布鲁诺·凯斯勒基金会)
In this paper, we present an automated approach for segmenting multiple sclerosis (MS) lesions from multi-modal brain magnetic resonance images. Our method is based on a deep end-to-end 2D convolutional neural network (CNN) for slice-based segmentation of 3D volumetric data. The proposed CNN includes a multi-branch downsampling path, which enables the network to encode information from multiple modalities separately. Multi-scale feature fusion blocks are proposed to combine feature maps from different modalities at different stages of the network. Then, multi-scale feature upsampling blocks ar…
MIT(麻省理工学院);Philips Research North America(飞利浦北美研究院)
We present a fully convolutional neural network for segmenting ischemic stroke lesions in CT perfusion images for the ISLES 2018 challenge. Treatment of stroke is time sensitive and current standards for lesion identification require manual segmentation, a time consuming and challenging process. Automatic segmentation methods present the possibility of accurately identifying lesions and improving treatment planning. Our model is based on the PSPNet, a network architecture that makes use of pyramid pooling to provide global and local contextual information. To learn the varying shapes of the le…
Shenyang Institute of Automation, Chinese Academy of Sciences(中国科学院沈阳自动化研究所);Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences(中国科学院机器人与智能制造创新研究院);University of Chinese Academy of Sciences(中国科学院大学);Chinese PLA General Hospital(中国人民解放军总医院);University of Arkansas at Little Rock(阿肯色大学小石城分校);Indiana University-Purdue University Indianapolis(印第安纳大学-普渡大学印第安纳波利斯分校)
Weakly-supervised learning has attracted growing research attention on medical lesions segmentation due to significant saving in pixel-level annotation cost. However, 1) most existing methods require effective prior and constraints to explore the intrinsic lesions characterization, which only generates incorrect and rough prediction; 2) they neglect the underlying semantic dependencies among weakly-labeled target enteroscopy diseases and fully-annotated source gastroscope lesions, while forcefully utilizing untransferable dependencies leads to the negative performance. To tackle above issues, …
Convolutional neural networks (CNNs) have achieved the state-of-the-art performance in skin lesion analysis. Compared with single CNN classifier, combining the results of multiple classifiers via fusion approaches shows to be more effective and robust. Since the skin lesion datasets are usually limited and statistically biased, while designing an effective fusion approach, it is important to consider not only the performance of each classifier on the training/validation dataset, but also the relative discriminative power (e.g., confidence) of each classifier regarding an individual sample in t…