A comparative study of 2D image segmentation algorithms for traumatic brain lesions using CT data from the ProTECTIII multicenter clinical trial
Warren Alpert Medical School of Brown University（布朗大学沃伦·阿尔珀特医学院）；Emory University School of Medicine（埃默里大学医学院）；University of Florida School of Medicine（佛罗里达大学医学院）；Brown University（布朗大学）
Shruti Jadon, Owen P. Leary, Ian Pan, Tyler J. Harder, David W. Wright, Lisa H. Merck, Derek L. Merck
Automated segmentation of medical imaging is of broad interest to clinicians and machine learning researchers alike. The goal of segmentation is to increase efficiency and simplicity of visualization and quantification of regions of interest within a medical image. Image segmentation is a difficult task because of multiparametric heterogeneity within the images, an obstacle that has proven especially challenging in efforts to automate the segmentation of brain lesions from non-contrast head computed tomography (CT). In this research, we have experimented with multiple available deep learning architectures to segment different phenotypes of hemorrhagic lesions found after moderate to severe traumatic brain injury (TBI). These include: intraparenchymal hemorrhage (IPH), subdural hematoma (SDH), epidural hematoma (EDH), and traumatic contusions. We were able to achieve an optimal Dice Coefficient1 score of 0.94 using UNet++ 2D Architecture with Focal Tversky Loss Function, an increase from 0.85 using UNet 2D with Binary Cross-Entropy Loss Function in intraparenchymal hemorrhage (IPH) cases. Furthermore, using the same setting, we were able to achieve the Dice Coefficient score of 0.90 and 0.86 in cases of Extra-Axial bleeds and Traumatic contusions, respectively.
Universidad de Buenos Aires（布宜诺斯艾利斯大学）；Universidad Nacional del Litoral（国立滨海大学）
Automatic segmentation of white matter hyperintensities in magnetic resonance images is of paramount clinical and research importance. Quantification of these lesions serve as a predictor for risk of stroke, dementia and mortality. During the last years, convolutional neural networks (CNN) specifically tailored for biomedical image segmentation have outperformed all previous techniques in this task. However, they are extremely data-dependent, and maintain a good performance only when data distribution between training and test datasets remains unchanged. When such distribution changes but we s…
The Chinese University of Hong Kong（香港中文大学）；The Hong Kong University of Science and Technology（香港科技大学）；Imsight Technology, Co., Ltd.（深圳视见科技有限公司）；The University of Hong Kong（香港大学）；Shenzhen People's Hospital（深圳市人民医院）；Guangdong Provincial People's Hospital（广东省人民医院）；Guangdong Academy of Medical Sciences（广东省医学科学院）；Queen Marry Hospital（玛丽医院）；Hospital Authority（医院管理局）；Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）
Two DL models were developed using radiograph-level annotations (yes or no disease) and fine-grained lesion-level annotations (lesion bounding boxes), respectively named CheXNet and CheXDet. The models' internal classification performance and lesion localization performance were compared on a testing set (n=2,922), external classification performance was compared on NIH-Google (n=4,376) and PadChest (n=24,536) datasets, and external lesion localization performance was compared on NIH-ChestX-ray14 dataset (n=880). The models were also compared to radiologists on a subset of the internal testing…
OvAi Focus: AI-based Multi-class Segmentation of Functional Ovaries and Adnexal Masses in Gynecological Ultrasound
Academic Division of Gynecology and Obstetrics, University of Turin（妇科与产科学术部，都灵大学）；Obstetric and Gynecology Unit, Ospedale Sant'Anna, Department of Surgical Sciences, University of Turin（妇产科单元，圣安娜医院，外科科学系，都灵大学）；Tel Aviv Sourasky Medical Center, Tel Aviv, Israel（特拉维夫 Sourasky 医疗中心，特拉维夫，以色列）
Shanghai Jiao Tong University（上海交通大学）；Huashan Hospital, Shanghai Medical College, Fudan University（复旦大学上海医学院华山医院）；National Center for Neurological Disorders（国家神经疾病中心）；Fudan University（复旦大学）；ShanghaiTech University（上海科技大学）
Brain network analysis for traumatic brain injury (TBI) patients is critical for its consciousness level assessment and prognosis evaluation, which requires the segmentation of certain consciousness-related brain regions. However, it is difficult to construct a TBI segmentation model as manually annotated MR scans of TBI patients are hard to collect. Data augmentation techniques can be applied to alleviate the issue of data scarcity. However, conventional data augmentation strategies such as spatial and intensity transformation are unable to mimic the deformation and lesions in traumatic brain…
Imperial College London（帝国理工学院）；University of Cambridge（剑桥大学）；Lund University（隆德大学）；Cambridge Univ. Hospitals NHS Foundation Trust（剑桥大学医院NHS基金会信托）；Technical University of Munich（慕尼黑工业大学）
Semi-supervised learning (SSL) uses unlabeled data during training to learn better models. Previous studies on SSL for medical image segmentation focused mostly on improving model generalization to unseen data. In some applications, however, our primary interest is not generalization but to obtain optimal predictions on a specific unlabeled database that is fully available during model development. Examples include population studies for extracting imaging phenotypes. This work investigates an often overlooked aspect of SSL, transduction. It focuses on the quality of predictions made on the un…
Autopet III challenge: Incorporating anatomical knowledge into nnUNet for lesion segmentation in PET/CT
Institute for AI in Medicine (IKIM)（医学人工智能研究所）；University Hospital Essen (AöR)（埃森大学医院）；Department of Nuclear Medicine（核医学科）；Cancer Research Center Cologne Essen (CCCE)（科隆埃森癌症研究中心）；West German Cancer Center Essen University Hospital Essen (AöR)（埃森大学医院西德癌症中心）；TU Dortmund（多特蒙德工业大学）；German Cancer Consortium (DKTK, Partner site Essen)（德国癌症联盟（埃森合作站点））
本研究针对 PET/CT 病变分割，提出基于示踪剂分类和集成 nnUNet 的方法，融合解剖标签，在 autoPET III 挑战中取得高 Dice 分数。
Clinical Melanoma Diagnosis with Artificial Intelligence: Insights from a Prospective Multicenter Study
German Cancer Research Center (DKFZ)（德国癌症研究中心（DKFZ））；University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg（海德堡鲁普雷希特-卡尔大学曼海姆医学中心）；DKFZ Hector Cancer Institute at the University Medical Center Mannheim（曼海姆医学中心DKFZ赫克托癌症研究所）；Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden（德累斯顿工业大学卡尔·古斯塔夫·卡鲁斯医学院暨大学医院）；University Hospital (UKSH), Kiel（基尔大学医院（UKSH））
Ultrasound-based detection and malignancy prediction of breast lesions eligible for biopsy: A multi-center clinical-scenario study using nomograms, large language models, and radiologist evaluation
Shahid Beheshti University of Medical Sciences（沙希德·贝赫什提医科大学）；Urmia University of Medical Science（乌尔米耶医科大学）；University of Health Sciences（健康科学大学）；Kartal Dr. Lütfi Kırdar City Hospital（卡尔塔尔·吕特菲·克尔达尔市医院）；University of Padova（帕多瓦大学）；Universal Scientific Education and Research Network (USERN)（全球科学教育与研究网络（USERN））；Tehran University of Medical Sciences（德黑兰医科大学）；Danube Private University（多瑙河私立大学）；Austrian Center for Medical Innovation and Technology (ACMIT)（奥地利医学创新与技术中心（ACMIT））；University of Southern Queensland（南昆士兰大学）
Background and objective: Parotid gland tumors account for approximately 2% to 10% of head and neck tumors. Preoperative tumor localization, differential diagnosis, and subsequent selection of appropriate treatment for parotid gland tumors are critical. However, the relative rarity of these tumors and the highly dispersed tissue types have left an unmet need for a subtle differential diagnosis of such neoplastic lesions based on preoperative radiomics. Recently, deep learning methods have developed rapidly, especially Transformer beats the traditional convolutional neural network in computer v…
Fed-NDIF: A Noise-Embedded Federated Diffusion Model For Low-Count Whole-Body PET Denoising
Yale University（耶鲁大学）；Northwestern University（西北大学）；Ruijin Hospital, Shanghai Jiao Tong University School of Medicine（上海交通大学医学院附属瑞金医院）；Inselspital, Bern University Hospital, University of Bern（伯尔尼大学医院 Inselspital，伯尔尼大学）；Technical University of Munich（慕尼黑工业大学）；Yale School of Medicine（耶鲁医学院）
University of Girona（赫罗纳大学）；Technical University of Munich（慕尼黑工业大学）；Antwerp University Hospital（安特卫普大学医院）；University of Antwerp（安特卫普大学）；KU Leuven（鲁汶大学）
Anomaly detection (AD) is the identification of data samples that do not fit a learned data distribution. As such, AD systems can help physicians to determine the presence, severity, and extension of a pathology. Deep generative models, such as Generative Adversarial Networks (GANs), can be exploited to capture anatomical variability. Consequently, any outlier (i.e., sample falling outside of the learned distribution) can be detected as an abnormality in an unsupervised fashion. By using this method, we can not only detect expected or known lesions, but we can even unveil previously unrecogniz…
The MYOSAIQ Challenge: Myocardial Segmentation with Automated Infarct Quantification
INSA-Lyon, Universite Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1294（里昂国立应用科学学院、里昂第一大学克洛德·贝尔纳大学、圣艾蒂安大学、法国国家科学研究中心、法国国家健康与医学研究院、CREATIS联合研究机构）；Institut Universitaire de France (IUF)（法兰西大学研究院）；University of Sherbrooke（谢布鲁克大学）；Huazhong University of Science and Technology（华中科技大学）；Sunnybrook Research Institute, University of Toronto（多伦多大学桑尼布鲁克研究所）；Imperial College London（伦敦帝国理工学院）；University College London（伦敦大学学院）；Fudan University（复旦大学）；Medical University of Graz（格拉茨医科大学）；Graz University of Technology（格拉茨技术大学）；Universidad de Zaragoza（萨拉戈萨大学）；Instituto de Investigación Sanitaria de Aragón (IIS Aragón)（阿拉贡卫生研究所）；Centre Hospitalier Annecy Genevois（阿讷西日内瓦中心医院）；Hôpital Universitaire Cardiologique Louis Pradel（路易·普拉德尔大学心脏病医院）
