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arXiv 2504.02408eess.IVcs.AIcs.CV
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使用人工智能将胎儿脑超声图像转换为伪MRI图像

Translation of Fetal Brain Ultrasound Images into Pseudo-MRI Images using Artificial Intelligence

Technion Institute of Technology(以色列理工学院);Rambam Health Care Campus(兰巴姆医疗中心)

Naomi Silverstein, Efrat Leibowitz, Ron Beloosesky, Haim Azhari

AI总结:

提出基于扩散模型的DDIC方法,将胎儿脑超声图像转换为伪MRI图像,在多项指标上显著优于其他方法,并在视觉辨别和医学意见测试中展现临床应用潜力。

摘要:

超声是一种广泛普及且具有成本效益的医学成像工具,通常用于胎儿大脑的产前评估。然而,它存在局限性,特别是在妊娠晚期,胎儿大脑的复杂性需要高图像质量才能提取定量数据。相比之下,磁共振成像(MRI)提供了卓越的图像质量和组织分化能力,但其普及度较低、价格昂贵且采集耗时。因此,将超声图像转换为类似MRI的显示方式可能具有优势,并能更好地呈现组织解剖结构。为实现这一目标,我们研究了人工智能的应用,采用以生成高质量图像而闻名的扩散模型。所提出的方法被称为“双重扩散施加相关性”(DDIC),利用基于扩散的转换方法,假设超声和MRI域之间存在共享的潜在空间。模型训练利用超声“HC18”数据集以及MRI的“CRL fetal brain atlas”和“FeTA”数据集进行。生成的伪MRI图像在脑组织的视觉辨别方面提供了显著改进,特别是在侧脑室和外侧裂,表现为对比度清晰度的增强。在互信息、峰值信噪比、Fréchet Inception Distance和对比度噪声比方面展示了改进。这些评估的发现表明,与其他转换方法相比,DDIC具有统计学上显著的优越性能。此外,还获得了5位妇产科医生的医学意见测试。结果显示,在81%的测试图像中展示出显示改进。总之,所提出的伪MRI图像通过改进的表示,具有简化诊断和改善临床结果的潜力。

英文摘要:

Ultrasound is a widely accessible and cost-effective medical imaging tool commonly used for prenatal evaluation of the fetal brain. However, it has limitations, particularly in the third trimester, where the complexity of the fetal brain requires high image quality for extracting quantitative data. In contrast, magnetic resonance imaging (MRI) offers superior image quality and tissue differentiation but is less available, expensive, and requires time-consuming acquisition. Thus, transforming ultrasonic images into an MRI-mimicking display may be advantageous and allow better tissue anatomy presentation. To address this goal, we have examined the use of artificial intelligence, implementing a diffusion model renowned for generating high-quality images. The proposed method, termed "Dual Diffusion Imposed Correlation" (DDIC), leverages a diffusion-based translation methodology, assuming a shared latent space between ultrasound and MRI domains. Model training was obtained utilizing the "HC18" dataset for ultrasound and the "CRL fetal brain atlas" along with the "FeTA " datasets for MRI. The generated pseudo-MRI images provide notable improvements in visual discrimination of brain tissue, especially in the lateral ventricles and the Sylvian fissure, characterized by enhanced contrast clarity. Improvement was demonstrated in Mutual information, Peak signal-to-noise ratio, Fréchet Inception Distance, and Contrast-to-noise ratio. Findings from these evaluations indicate statistically significant superior performance of the DDIC compared to other translation methodologies. In addition, a Medical Opinion Test was obtained from 5 gynecologists. The results demonstrated display improvement in 81% of the tested images. In conclusion, the presented pseudo-MRI images hold the potential for streamlining diagnosis and enhancing clinical outcomes through improved representation.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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