Volumetric measurements of fetal structures in MRI are time consuming and error prone and therefore require automatic segmentation. Placenta segmentation and accurate fetal brain segmentation for gyrification assessment are particularly challenging because of the placenta fuzzy boundaries and the fetal brain cortex complex foldings. In this paper, we study the use of the Contour Dice loss for both problems and compare it to other boundary losses and to the combined Dice and Cross-Entropy loss. The loss is computed efficiently for each slice via erosion, dilation and XOR operators. We describe a new formulation of the loss akin to the Contour Dice metric. The combination of the Dice loss and the Contour Dice yielded the best performance for placenta segmentation. For fetal brain segmentation, the best performing loss was the combined Dice with Cross-Entropy loss followed by the Dice with Contour Dice loss, which performed better than other boundary losses.
University Hospitals Leuven（鲁汶大学医院）；University Hospitals Tanta（坦塔大学医院）；University College London（伦敦大学学院）
Deep neural networks have increased the accuracy of automatic segmentation, however, their accuracy depends on the availability of a large number of fully segmented images. Methods to train deep neural networks using images for which some, but not all, regions of interest are segmented are necessary to make better use of partially annotated datasets. In this paper, we propose the first axiomatic definition of label-set loss functions that are the loss functions that can handle partially segmented images. We prove that there is one and only one method to convert a classical loss function for fu…
The Hebrew University of Jerusalem（耶路撒冷希伯来大学）；Sagol Brain Institute, Tel Aviv Medical Center（特拉维夫医疗中心萨戈尔脑研究所）；Tel Aviv Medical Center（特拉维夫医疗中心）；Tel Aviv University（特拉维夫大学）；Tel Aviv Sourasky Medical Center（特拉维夫苏拉斯基医疗中心）
Normal fetal adipose tissue (AT) development is essential for perinatal well-being. AT, or simply fat, stores energy in the form of lipids. Malnourishment may result in excessive or depleted adiposity. Although previous studies showed a correlation between the amount of AT and perinatal outcome, prenatal assessment of AT is limited by lacking quantitative methods. Using magnetic resonance imaging (MRI), 3D fat- and water-only images of the entire fetus can be obtained from two point Dixon images to enable AT lipid quantification. This paper is the first to present a methodology for developing …
Imperial College London（伦敦帝国学院）；King’s College London（伦敦国王学院）；FAU Erlangen-Nürnberg（埃尔朗根-纽伦堡大学）；Technical University of Munich（慕尼黑工业大学）
Fetal Magnetic Resonance Imaging (MRI) is used in prenatal diagnosis and to assess early brain development. Accurate segmentation of the different brain tissues is a vital step in several brain analysis tasks, such as cortical surface reconstruction and tissue thickness measurements. Fetal MRI scans, however, are prone to motion artifacts that can affect the correctness of both manual and automatic segmentation techniques. In this paper, we propose a novel network structure that can simultaneously generate conditional atlases and predict brain tissue segmentation, called CAS-Net. The condition…
Northeastern University（东北大学）；Boston Children’s Hospital（波士顿儿童医院）；Harvard Medical School（哈佛医学院）
Fetal brain segmentation is an important first step for slice-level motion correction and slice-to-volume reconstruction in fetal MRI. Fast and accurate segmentation of the fetal brain on fetal MRI is required to achieve real-time fetal head pose estimation and motion tracking for slice re-acquisition and steering. To address this critical unmet need, in this work we analyzed the speed-accuracy performance of a variety of deep neural network models, and devised a symbolically small convolutional neural network that combines spatial details at high resolution with context features extracted at …
Evaluating Synthetic Data Generation for Domain Generalization in Fetal Brain MRI Segmentation
Department of Radiology, Lausanne University Hospital and University of Lausanne (UNIL)（拉沃斯大学医院放射科和洛桑大学（UNIL））；CIBM Center for Biomedical Imaging（生物医学成像中心）；Institute for Information Processing, Leibniz University Hannover（汉诺威莱比锡大学信息处理研究所）；Department of Biomedical Engineering, School of Biomedical Engineering & Imaging Sciences, King’s College London（伦敦国王学院生物医学工程系）；Department of Biomedical Imaging and Image-Guided Therapy, Division of Neuroradiology and Musculoskeletal Radiology, Medical University of Vienna（维也纳医学大学生物医学成像与影像引导治疗系）；Department of Biomedical Imaging and Image-guided Therapy, Computational Imaging Research Lab (CIR), Medical University of Vienna（维也纳医学大学生物医学成像与影像引导治疗系，计算成像研究实验室（CIR））；Christian Doppler Laboratory for Mathematical Modelling and Simulation of Next-Generation Medical Ultrasound Devices, Medical University of Vienna（维也纳医学大学下一代医学超声设备数学建模与仿真克里斯蒂安多普勒实验室）；Comprehensive Center for Artificial Intelligence in Medicine, Medical University of Vienna（维也纳医学大学人工智能在医学中的综合中心）；Division of Neuroradiology and Musculoskeletal Radiology, Department of Biomedical Imaging and Image–guided Therapy, Medical University of Vienna（维也纳医学大学生物医学成像与影像引导治疗系，神经放射学和骨科放射学系）
Enhancing Generalized Fetal Brain MRI Segmentation using A Cascade Network with Depth-wise Separable Convolution and Attention Mechanism
Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University（复旦大学类脑智能科学与技术研究院）；MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence（教育部计算神经科学与类脑智能重点实验室）；MOE Frontiers Center for Brain Science（教育部脑科学前沿中心）
Fetal cortical plate segmentation is essential in quantitative analysis of fetal brain maturation and cortical folding. Manual segmentation of the cortical plate, or manual refinement of automatic segmentations is tedious and time-consuming. Automatic segmentation of the cortical plate, on the other hand, is challenged by the relatively low resolution of the reconstructed fetal brain MRI scans compared to the thin structure of the cortical plate, partial voluming, and the wide range of variations in the morphology of the cortical plate as the brain matures during gestation. To reduce the burde…
AtlasSeg: Atlas Prior Guided Dual-U-Net for Cortical Segmentation in Fetal Brain MRI
College of Biomedical Engineering & Instrument Science, Zhejiang University（浙江大学生物医学工程与仪器科学学院）；Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences（中国医学科学院北京医院国家老年医学中心老年医学研究所）；Shandong Provincial Hospital Affiliated to Shandong First Medical University（山东第一医科大学附属山东省立医院）；State Key Lab of CAD&CG, Zhejiang University（浙江大学CAD&CG国家重点实验室）
Deep Learning-Based Fetal Lung Segmentation from Diffusion-weighted MRI Images and Lung Maturity Evaluation for Fetal Growth Restriction
School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK（生物医学工程与成像科学学院，伦敦国王学院）；Elizabeth Garrett Anderson Institute for Women’s Health, University College, London, UK（埃利扎贝塔·加德纳妇女健康研究所，大学学院，伦敦）；University College London Hospital NHS Foundation Trust, London, UK（伦敦大学学院医院国家健康服务信托基金）；Department of Medical Physics and Biomedical Engineering, University College London Hospitals, London, UK（医学物理与生物医学工程系，伦敦大学学院医院）；Department of Radiology, University College London Hospitals NHS Foundation Trust, London, United Kingdom（放射科，伦敦大学学院医院国家健康服务信托基金）
Detailed delineation of the fetal brain in diffusion MRI via multi-task learning
Harvard Medical School（哈佛医学院）；Elmhurst Hospital Center（埃尔姆赫斯特医院中心）；Icahn School of Medicine at Mount Sinai（西奈山伊坎医学院）；Massachusetts General Hospital（麻省总医院）；University of California Irvine（加州大学欧文分校）
Boston Children’s Hospital（波士顿儿童医院）；Harvard Medical School（哈佛医学院）
Automatic fetal brain tissue segmentation can enhance the quantitative assessment of brain development at this critical stage. Deep learning methods represent the state of the art in medical image segmentation and have also achieved impressive results in brain segmentation. However, effective training of a deep learning model to perform this task requires a large number of training images to represent the rapid development of the transient fetal brain structures. On the other hand, manual multi-label segmentation of a large number of 3D images is prohibitive. To address this challenge, we segm…
ResNet-34 with Lightweight Decoder for Accurate and Efficient Segmentation of Fetal Brain MRI
Department of Biomedical Physics and Technology, University of Dhaka（达卡大学生物医学物理与技术系）；Department of Electrical Engineering, College of Engineering, Qatar University（卡塔尔大学工程学院电气工程系）；Department of Biomedical Engineering, Jashore University of Science and Technology（贾沙尔大学科学与技术学院生物医学工程系）
One of the main requirements of tumor extraction is the annotation and segmentation of tumor boundaries correctly. For this purpose, we present a threefold deep learning architecture. First classifiers are implemented with a deep convolutional neural network(CNN) andsecond a region-based convolutional neural network (R-CNN) is performed on the classified images to localize the tumor regions of interest. As the third and final stage, the concentratedtumor boundary is contoured for the segmentation process by using the Chan-Vesesegmentation algorithm. As the typical edge detection algorithms bas…
Medical Image Segmentation based on Deep Active Contour and Mean Curvature Loss Function
Henan Provincial Center for Applied Mathematics, Henan University（河南大学河南省应用数学中心）；College of Mathematics and Statistics, Henan University（河南大学数学与统计学院）；Advanced Institute of Finance, Henan University（河南大学高等金融研究院）；School of Software, Henan Agricultural University（河南农业大学软件学院）
Isfahan University of Technology（伊斯法罕理工大学）；University of Michigan（密歇根大学）
Ultrasound imaging is a standard examination during pregnancy that can be used for measuring specific biometric parameters towards prenatal diagnosis and estimating gestational age. Fetal head circumference (HC) is one of the significant factors to determine the fetus growth and health. In this paper, a multi-task deep convolutional neural network is proposed for automatic segmentation and estimation of HC ellipse by minimizing a compound cost function composed of segmentation dice score and MSE of ellipse parameters. Experimental results on fetus ultrasound dataset in different trimesters of …
Detecting acoustic shadows in ultrasound images is important in many clinical and engineering applications. Real-time feedback of acoustic shadows can guide sonographers to a standardized diagnostic viewing plane with minimal artifacts and can provide additional information for other automatic image analysis algorithms. However, automatically detecting shadow regions using learning-based algorithms is challenging because pixel-wise ground truth annotation of acoustic shadows is subjective and time consuming. In this paper we propose a weakly supervised method for automatic confidence estimatio…
Although supervised deep-learning has achieved promising performance in medical image segmentation, many methods cannot generalize well on unseen data, limiting their real-world applicability. To address this problem, we propose a deep learning-based Bayesian framework, which jointly models image and label statistics, utilizing the domain-irrelevant contour of a medical image for segmentation. Specifically, we first decompose an image into components of contour and basis. Then, we model the expected label as a variable only related to the contour. Finally, we develop a variational Bayesian fra…
IBM Research – Almaden Research Center（IBM阿尔马登研究中心）；Eastern Virginia Medical School（东弗吉尼亚医学院）
Congenital heart disease (CHD) is the most common congenital abnormality associated with birth defects in the United States. Despite training efforts and substantial advancement in ultrasound technology over the past years, CHD remains an abnormality that is frequently missed during prenatal ultrasonography. Therefore, computer-aided detection of CHD can play a critical role in prenatal care by improving screening and diagnosis. Since many CHDs involve structural abnormalities, automatic segmentation of anatomical structures is an important step in the analysis of fetal echocardiograms. While …
The Hebrew University of Jerusalem（耶路撒冷希伯来大学）；Tel Aviv Sourasky Medical Center（特拉维夫苏拉斯基医疗中心）；Tel Aviv University（特拉维夫大学）；Children’s Hospital of Eastern Ontario（东安大略儿童医院）；University of Ottawa（渥太华大学）
Deep learning methods have been shown to be effective for the automatic segmentation of structures and pathologies in medical imaging. However, they require large annotated datasets, whose manual segmentation is a tedious and time-consuming task, especially for large structures. We present a new method of partial annotations that uses a small set of consecutive annotated slices from each scan with an annotation effort that is equal to that of only few annotated cases. The training with partial annotations is performed by using only annotated blocks, incorporating information about slices outsi…
Massachusetts Institute of Technology（麻省理工学院）；MGH/HST Martinos Center for Biomedical Imaging（麻省总医院/健康科学与技术部马蒂诺斯生物医学成像中心）；Harvard Medical School（哈佛医学院）；Boston Children’s Hospital（波士顿儿童医院）
Blood oxygen level dependent (BOLD) MRI with maternal hyperoxia can assess oxygen transport within the placenta and has emerged as a promising tool to study placental function. Measuring signal changes over time requires segmenting the placenta in each volume of the time series. Due to the large number of volumes in the BOLD time series, existing studies rely on registration to map all volumes to a manually segmented template. As the placenta can undergo large deformation due to fetal motion, maternal motion, and contractions, this approach often results in a large number of discarded volumes,…
University of Electronic Science and Technology of China（电子科技大学）；SenseTime Research（商汤科技研究院）；University Hospitals Leuven（鲁汶大学医院）；King’s College London（伦敦国王学院）；University College London（伦敦大学学院）
Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are still challenged by complicated conditions where the segmentation target has large variations of position, shape and scale, and existing CNNs have a poor explainability that limits their application to clinical decisions. In this work, we make extensive use of multiple attentions in a CNN architecture and propose a comprehensive attention-based CNN (CA-Net) f…
Automatic segmentation of myocardial contours and relevant areas like infraction and no-reflow is an important step for the quantitative evaluation of myocardial infarction. In this work, we propose a cascaded convolutional neural network for automatic myocardial infarction segmentation from delayed-enhancement cardiac MRI. We first use a 2D U-Net to focus on the intra-slice information to perform a preliminary segmentation. After that, we use a 3D U-Net to utilize the volumetric spatial information for a subtle segmentation. Our method is evaluated on the MICCAI 2020 EMIDEC challenge dataset …
Entropy-Guided Agreement-Diversity: A Semi-Supervised Active Learning Framework for Fetal Head Segmentation in Ultrasound
Taighde \' E ireann – Research Ireland Centre for Research Training in Machine Learning, Ireland School of Computer Science, University College Dublin, Ireland School of Medicine, University College Dublin, Ireland
The Chinese University of Hong Kong（香港中文大学）；Shenzhen University（深圳大学）；Affiliated Shenzhen Maternal and Child Healthcare Hospital of Nanfang Medical University（南方医科大学附属深圳妇幼保健院）
Background and Objective: Biometric measurements of fetal head are important indicators for maternal and fetal health monitoring during pregnancy. 3D ultrasound (US) has unique advantages over 2D scan in covering the whole fetal head and may promote the diagnoses. However, automatically segmenting the whole fetal head in US volumes still pends as an emerging and unsolved problem. The challenges that automated solutions need to tackle include the poor image quality, boundary ambiguity, long-span occlusion, and the appearance variability across different fetal poses and gestational ages. In this…
Dual Agreement Consistency Learning for Semi-Supervised Fetal Ultrasound Segmentation
Research Ireland Centre for Research Training in Machine Learning（爱尔兰研究机器学习研究中心）；School of Medicine, University College Dublin（都柏林大学医学院）；School of Computer Science, University College Dublin（都柏林大学计算机科学学院）；School of Computer Science and Digital Technologies, Aston University（阿斯顿大学计算机科学与数字技术学院）
Diffusion Model-based Data Augmentation Method for Fetal Head Ultrasound Segmentation
Research Ireland Centre for Research Training in Machine Learning（爱尔兰研究机器学习研究中心）；School of Medicine, University College Dublin（都柏林大学医学院）；School of Computer Science, University College Dublin（都柏林大学计算机科学学院）
University of Idaho（爱达荷大学）；Hunan University of Technology of Business（湖南工商大学）
Separating overlapped nuclei is a major challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on nuclei segmentation; however, their performance on separating overlapped nuclei is quite limited. To address the issue, we propose a novel multitask learning network with a bending loss regularizer to separate overlapped nuclei accurately. The newly proposed multitask learning architecture enhances the generalization by learning shared representation from three tasks: instance segmentation, nuclei distance map prediction, and overlappe…
The pandemic of novel SARS-CoV-2 also known as COVID-19 has been spreading worldwide, causing rampant loss of lives. Medical imaging such as CT, X-ray, etc., plays a significant role in diagnosing the patients by presenting the visual representation of the functioning of the organs. However, for any radiologist analyzing such scans is a tedious and time-consuming task. The emerging deep learning technologies have displayed its strength in analyzing such scans to aid in the faster diagnosis of the diseases and viruses such as COVID-19. In the present article, an automated deep learning based mo…
University of Electronic Science and Technology of China（电子科技大学）；SenseTime Research（商汤科技研究院）
Despite that deep learning has achieved state-of-the-art performance for medical image segmentation, its success relies on a large set of manually annotated images for training that are expensive to acquire. In this paper, we propose an annotation-efficient learning framework for segmentation tasks that avoids annotations of training images, where we use an improved Cycle-Consistent Generative Adversarial Network (GAN) to learn from a set of unpaired medical images and auxiliary masks obtained either from a shape model or public datasets. We first use the GAN to generate pseudo labels for our …
Conditional Fetal Brain Atlas Learning for Automatic Tissue Segmentation
Computational Imaging Research Lab（计算成像研究实验室）；Department of Biomedical Imaging and Image-guided Therapy（生物医学成像与影像引导治疗部门）；Medical University of Vienna（维也纳医科大学）；Comprehensive Center for Artificial Intelligence in Medicine（医学人工智能综合中心）；Division of General Radiology（普通放射学分会）；Medical University Vienna（维也纳医科大学）；Christian Doppler Laboratory for Mathematical Modelling and Simulation of Next-Generation Medical Ultrasound Devices（基督教·多普勒医学影像建模与模拟实验室）
Universitair Ziekenhuis Leuven（鲁汶大学医院）；Medical University of Vienna（维也纳医科大学）；King’s College London（伦敦国王学院）
In fetal Magnetic Resonance Imaging, Super Resolution Reconstruction (SRR) algorithms are becoming popular tools to obtain high-resolution 3D volume reconstructions from low-resolution stacks of 2D slices, acquired at different orientations. To be effective, these algorithms often require accurate segmentation of the region of interest, such as the fetal brain in suspected pathological cases. In the case of Spina Bifida, Ebner, Wang et al. (NeuroImage, 2020) combined their SRR algorithm with a 2-step segmentation pipeline (2D localisation followed by a 2D segmentation network). However, if the…
HES-SO Valais-Wallis University of Applied Sciences and Arts Western Switzerland（瑞士西部应用科学与艺术大学瓦莱州分校）；Centre Hospitalier Universitaire Vaudois (CHUV)（沃州大学中心医院）；Centre Hospitalier Universitaire de Poitiers (CHUP)（普瓦捷大学中心医院）；Univ Brest（布雷斯特大学）；INSERM（法国国家健康与医学研究院）；LaTIM（医学信息处理实验室）；Cleveland Clinic Foundation（克利夫兰医学中心基金会）；University of Sherbrooke（舍布鲁克大学）
This paper presents an overview of the second edition of the HEad and neCK TumOR (HECKTOR) challenge, organized as a satellite event of the 24th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI) 2021. The challenge is composed of three tasks related to the automatic analysis of PET/CT images for patients with Head and Neck cancer (H&N), focusing on the oropharynx region. Task 1 is the automatic segmentation of H&N primary Gross Tumor Volume (GTVt) in FDG-PET/CT images. Task 2 is the automatic prediction of Progression Free Survival (PFS) from the s…
Stanford University（斯坦福大学）；University of California, San Diego Medical Center（加州大学圣地亚哥医学中心）
We propose a novel method, the adaptive local window, for improving level set segmentation technique. The window is estimated separately for each contour point, over iterations of the segmentation process, and for each individual object. Our method considers the object scale, the spatial texture, and changes of the energy functional over iterations. Global and local statistics are considered by calculating several gray level co-occurrence matrices. We demonstrate the capabilities of the method in the domain of medical imaging for segmenting 233 images with liver lesions. To illustrate the stre…
UPL-SFDA: Uncertainty-aware Pseudo Label Guided Source-Free Domain Adaptation for Medical Image Segmentation
School of Mechanical and Electrical Engineering, University of Electronic Science and Technology of China（电子科技大学机械与电气工程学院）；Shanghai AI laboratory（上海人工智能实验室）；Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China（电子科技大学附属四川省人民医院）；SenseTime Research（商汤科技研究院）；Zhejiang Laboratory（浙江实验室）；School of Biomedical Engineering & Imaging Sciences, King’s College London（伦敦国王学院生物医学工程与影像科学学院）
National Heart & Lung Institute, Imperial College London（伦敦帝国理工学院国家心肺研究所）；Royal Brompton Hospital（皇家布朗普顿医院）
Four-dimensional (4D) left ventricular myocardial velocity mapping (MVM) is a cardiac magnetic resonance (CMR) technique that allows assessment of cardiac motion in three orthogonal directions. Accurate and reproducible delineation of the myocardium is crucial for accurate analysis of peak systolic and diastolic myocardial velocities. In addition to the conventionally available magnitude CMR data, 4D MVM also acquires three velocity-encoded phase datasets which are used to generate velocity maps. These can be used to facilitate and improve myocardial delineation. Based on the success of deep l…
Origin Health India（印度Origin Health）；Bangalore Fetal Medicine Center（班加罗尔胎儿医学中心）；Prime Imaging and Prenatal Diagnostics（Prime影像与产前诊断中心）；Kasturba Medical College, Manipal Academy of Higher Education（马尼帕尔高等教育学院卡斯特尔巴医学院）；Origin Health；Universiti Malaya（马来亚大学）；Aarthi Scans and Labs（Aarthi扫描与实验室）
Quality assessment of prenatal ultrasonography is essential for the screening of fetal central nervous system (CNS) anomalies. The interpretation of fetal brain structures is highly subjective, expertise-driven, and requires years of training experience, limiting quality prenatal care for all pregnant mothers. With recent advancement in Artificial Intelligence (AI), specifically deep learning (DL), assistance in precise anatomy identification through semantic segmentation essential for the reliable assessment of growth and neurodevelopment, and detection of structural abnormalities have been p…
University of Texas Southwestern Medical Center（德克萨斯大学西南医学中心）；Mayo Clinic（梅奥诊所）；Southern Methodist University（南卫理公会大学）
Automatic segmentation of medical images with DL algorithms has proven to be highly successful. With most of these algorithms, inter-observer variation is an acknowledged problem, leading to sub-optimal results. This problem is even more significant in post-operative clinical target volume (post-op CTV) segmentation due to the absence of macroscopic visual tumor in the image. This study, using post-op CTV segmentation as the test bed, tries to determine if physician styles are consistent and learnable, if there is an impact of physician styles on treatment outcome and toxicity; and how to expl…
Three-dimensional (3D) integrated renal structures (IRS) segmentation is important in clinical practice. With the advancement of deep learning techniques, many powerful frameworks focusing on medical image segmentation are proposed. In this challenge, we utilized the nnU-Net framework, which is the state-of-the-art method for medical image segmentation. To reduce the outlier prediction for the tumor label, we combine contour regularization (CR) loss of the tumor label with Dice loss and cross-entropy loss to improve this phenomenon.
Nanjing University of Science and Technology（南京理工大学）；Nanjing University（南京大学）
Automatic segmentation of head and neck tumors plays an important role in radiomics analysis. In this short paper, we propose an automatic segmentation method for head and neck tumors from PET and CT images based on the combination of convolutional neural networks (CNNs) and hybrid active contours. Specifically, we first introduce a multi-channel 3D U-Net to segment the tumor with the concatenated PET and CT images. Then, we estimate the segmentation uncertainty by model ensembles and define a segmentation quality score to select the cases with high uncertainties. Finally, we develop a hybrid …
Detecting and segmenting individual cells from microscopy images is critical to various life science applications. Traditional cell segmentation tools are often ill-suited for applications in brightfield microscopy due to poor contrast and intensity heterogeneity, and only a small subset are applicable to segment cells in a cluster. In this regard, we introduce a novel supervised technique for cell segmentation in a multi-task learning paradigm. A combination of a multi-task loss, based on the region and cell boundary detection, is employed for an improved prediction efficiency of the network.…
ImViA Laboratory, University of Burgundy（勃艮第大学ImViA实验室）；CHU Dijon（第戎大学医院）；CGFL；Institut Curie（居里研究所）
In this paper, we propose a new deep learning framework for an automatic myocardial infarction evaluation from clinical information and delayed enhancement-MRI (DE-MRI). The proposed framework addresses two tasks. The first task is automatic detection of myocardial contours, the infarcted area, the no-reflow area, and the left ventricular cavity from a short-axis DE-MRI series. It employs two segmentation neural networks. The first network is used to segment the anatomical structures such as the myocardium and left ventricular cavity. The second network is used to segment the pathological area…
University of Toronto（多伦多大学）；Lunenfeld-Tanenbaum Research Institute, Sinai Health System（Sinai Health System 伦内菲尔德-塔嫩鲍姆研究所）；Brigham and Women’s Hospital（布莱根妇女医院）；The Hospital for Sick Children（SickKids 医院）
The segmentation of prostate whole gland and transition zone in Diffusion Weighted MRI (DWI) are the first step in designing computer-aided detection algorithms for prostate cancer. However, variations in MRI acquisition parameters and scanner manufacturing result in different appearances of prostate tissue in the images. Convolutional neural networks (CNNs) which have shown to be successful in various medical image analysis tasks including segmentation are typically sensitive to the variations in imaging parameters. This sensitivity leads to poor segmentation performance of CNNs trained on a …
Carotid artery vessel wall thickness measurement is an essential step in the monitoring of patients with atherosclerosis. This requires accurate segmentation of the vessel wall, i.e., the region between an artery's lumen and outer wall, in black-blood magnetic resonance (MR) images. Commonly used convolutional neural networks (CNNs) for semantic segmentation are suboptimal for this task as their use does not guarantee a contiguous ring-shaped segmentation. Instead, in this work, we cast vessel wall segmentation as a multi-task regression problem in a polar coordinate system. For each carotid a…
Segmentation of the left ventricle (LV) from cardiac magnetic resonance imaging (MRI) datasets is an essential step for calculation of clinical indices such as ventricular volume and ejection fraction. In this work, we employ deep learning algorithms combined with deformable models to develop and evaluate a fully automatic segmentation tool for the LV from short-axis cardiac MRI datasets. The method employs deep learning algorithms to learn the segmentation task from the ground true data. Convolutional networks are employed to automatically detect the LV chamber in MRI dataset. Stacked autoenc…
Quantitative analysis of vessel wall structures by automated vessel wall segmentation provides useful imaging biomarkers in evaluating atherosclerotic lesions and plaque progression time-efficiently. To quantify vessel wall features, drawing lumen and outer wall contours of the artery of interest is required. To alleviate manual labor in contour drawing, some computer-assisted tools exist, but manual preprocessing steps, such as region of interest identification and boundary initialization are needed. In addition, the prior knowledge of the ring shape of vessel wall is not taken into considera…
