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arXiv 2410.19682stat.MEstat.CO
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trajmsm:一个用于轨迹分析和因果建模的 R 包

trajmsm: An R package for Trajectory Analysis and Causal Modeling

Awa Diop, Caroline Sirois, Jason R. Guertin, Mireille E. Schnitzer, James M. Brophy, Denis Talbot

AI总结:

本文介绍 R 包 trajmsm,用于实现 LCGA 与 MSM/HRMSM 结合的轨迹因果建模,并支持 IPW、g-计算和 pooled LTMLE 三种估计方法。

摘要:

R 包 trajmsm 提供了一系列函数,旨在简化结合潜在类别增长分析(LCGA,一种轨迹分析技术)与边际结构模型(MSM)的模型(称为 LCGA-MSM)的参数估计。LCGA 将随时间变化的相似变化模式归纳为少数几个不同的类别,称为轨迹组,随后这些轨迹组作为“处理”被纳入 MSM。MSM 是一类能够正确处理处理—混杂因素反馈的因果模型。LCGA-MSM 的参数可以使用不同的估计量进行一致估计,例如逆概率加权(IPW)、g-计算以及合并纵向靶向最大似然估计(pooled LTMLE)。目前,我们的包已实现 LCGA-MSM 参数的这三种估计量。在时间依赖结局的背景下,我们此前提出了 LCGA 与历史受限 MSM(LCGA-HRMSM)的组合。本包还提供了额外的函数来估计此类模型的参数。该包的 0.1.3 版本目前已在 CRAN 上提供。

英文摘要:

The R package trajmsm provides functions designed to simplify the estimation of the parameters of a model combining latent class growth analysis (LCGA), a trajectory analysis technique, and marginal structural models (MSMs) called LCGA-MSM. LCGA summarizes similar patterns of change over time into a few distinct categories called trajectory groups, which are then included as "treatments" in the MSM. MSMs are a class of causal models that correctly handle treatment-confounder feedback. The parameters of LCGA-MSMs can be consistently estimated using different estimators, such as inverse probability weighting (IPW), g-computation, and pooled longitudinal targeted maximum likelihood estimation (pooled LTMLE). These three estimators of the parameters of LCGA-MSMs are currently implemented in our package. In the context of a time-dependent outcome, we previously proposed a combination of LCGA and history-restricted MSMs (LCGA-HRMSMs). Our package provides additional functions to estimate the parameters of such models. Version 0.1.3 of the package is currently available on CRAN.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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