arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 1806.01899stat.MLcs.LG
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MRPC:一个用于因果图精确推理的R软件包

MRPC: An R package for accurate inference of causal graphs

University of Idaho(爱达荷大学)

Md. Bahadur Badsha, Evan A Martin, Audrey Qiuyan Fu

摘要:

我们提出了MRPC,这是一个R包,它可以学习因果图,并且比现有的包(如pcalg和bnlearn)具有更高的准确性。我们的算法建立在功能强大的PC算法,在计算机科学中学习有向无环图的规范算法。准确性的提高来自于减少假阳性边缘的错误发现率(FDR)的在线控制,这是识别v结构(即,$T_1 \rightarrow T_2 \leftarrow T_3$)和节点间相关矩阵的稳健估计。对于包含每个样本的基因型和基因表达的基因组数据,MRPC采用孟德尔随机化原则来定位边缘。我们的软件包可以应用于连续和离散数据。

英文摘要:

We present MRPC, an R package that learns causal graphs with improved accuracy over existing packages, such as pcalg and bnlearn. Our algorithm builds on the powerful PC algorithm, the canonical algorithm in computer science for learning directed acyclic graphs. The improvement in accuracy results from online control of the false discovery rate (FDR) that reduces false positive edges, a more accurate approach to identifying v-structures (i.e., $T_1 \rightarrow T_2 \leftarrow T_3$), and robust estimation of the correlation matrix among nodes. For genomic data that contain genotypes and gene expression for each sample, MRPC incorporates the principle of Mendelian randomization to orient the edges. Our package can be applied to continuous and discrete data.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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