arXivDaily arXiv每日学术速递 周一至周五更新
arXiv周末暂无论文更新,休息一下吧,周末愉快~~
arXiv 2308.07495eess.IVeess.SP

基于肿瘤像素分布新型高质量预测的脑肿瘤检测

Brain Tumor Detection Based on a Novel and High-Quality Prediction of the Tumor Pixel Distributions

Yanming Sun, Chunyan Wang

AI总结:

本文提出一种基于2D直方图与左右不对称性、分三步预测肿瘤像素分布并生成掩膜的脑肿瘤检测系统,无需训练,计算成本低,在BraTS 2018~21上性能媲美CNN。

摘要:

本文提出了一种在Flair模态的3D MRI脑部扫描中检测脑肿瘤的系统。该系统执行两个功能:(a)预测肿瘤区域像素的灰度级和位置分布;(b)生成像素级精度的肿瘤掩膜。为便于3D数据的分析和处理,我们引入了一种2D直方图表示方法,该方法综合了3D物体的灰度级分布和像素位置分布。在所提出的系统中,通过利用大脑结构的左右不对称性,建立了特定的2D直方图,其中肿瘤相关特征数据得以集中。根据每个患者病例的输入数据生成调制函数,并将其应用于2D直方图,以衰减与肿瘤区域无关的元素。肿瘤像素分布的预测分三步进行,分别在轴向、冠状和矢状切片序列上进行。在每一步中,预测结果有助于识别/去除无肿瘤切片,从而提高剩余数据中的肿瘤信息密度,以供下一步使用。经过三步去除后,3D输入被缩减为肿瘤区域的最小包围盒。该包围盒用于完成预测,并通过灰度阈值化和基于低通滤波的形态学操作转换为3D肿瘤掩膜。最终的预测结果用于确定关键阈值。该系统已使用BraTS 2018~21数据集中超过一千个患者病例的数据进行了广泛测试。测试结果表明,预测的2D直方图与真实直方图具有高度相似性。该系统还提供了非常好的肿瘤检测结果,与使用单模态输入的先进CNN系统相当,且计算成本极低,无需训练。

英文摘要:

In this paper, we propose a system to detect brain tumor in 3D MRI brain scans of Flair modality. It performs 2 functions: (a) predicting gray-level and locational distributions of the pixels in the tumor regions and (b) generating tumor mask in pixel-wise precision. To facilitate 3D data analysis and processing, we introduced a 2D histogram presentation that comprehends the gray-level distribution and pixel-location distribution of a 3D object. In the proposed system, particular 2D histograms, in which tumor-related feature data get concentrated, are established by exploiting the left-right asymmetry of a brain structure. A modulation function is generated from the input data of each patient case and applied to the 2D histograms to attenuate the element irrelevant to the tumor regions. The prediction of the tumor pixel distribution is done in 3 steps, on the axial, coronal and sagittal slice series, respectively. In each step, the prediction result helps to identify/remove tumor-free slices, increasing the tumor information density in the remaining data to be applied to the next step. After the 3-step removal, the 3D input is reduced to a minimum bounding box of the tumor region. It is used to finalize the prediction and then transformed into a 3D tumor mask, by means of gray level thresholding and low-pass-based morphological operations. The final prediction result is used to determine the critical threshold. The proposed system has been tested extensively with the data of more than one thousand patient cases in the datasets of BraTS 2018~21. The test results demonstrate that the predicted 2D histograms have a high degree of similarity with the true ones. The system delivers also very good tumor detection results, comparable to those of state-of-the-art CNN systems with mono-modality inputs, which is achieved at an extremely low computation cost and no need for training.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑