Horacio Corral, Javier Melchor, Balam Sotelo, Jorge Vera
An algorithm capable of processing NMR images was developed for analysis using machine learning techniques to detect the presence of brain tumors.
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The magnetic resonance (MR) analysis of brain tumors is widely used for diagnosis and examination of tumor subregions. The overlapping area among the intensity distribution of healthy, enhancing, non-enhancing, and edema regions makes the automatic segmentation a challenging task. Here, we show that a convolutional neural network trained on high-contrast images can transform the intensity distribution of brain lesions in its internal subregions. Specifically, a generative adversarial network (GAN) is extended to synthesize high-contrast images. A comparison of these synthetic images and real i…
Brain tumor segmentation intends to delineate tumor tissues from healthy brain tissues. The tumor tissues include necrosis, peritumoral edema, and active tumor. In contrast, healthy brain tissues include white matter, gray matter, and cerebrospinal fluid. The MRI based brain tumor segmentation research is gaining popularity as; 1. It does not irradiate ionized radiation like X-ray or computed tomography imaging. 2. It produces detailed pictures of internal body structures. The MRI scans are input to deep learning-based approaches which are useful for automatic brain tumor segmentation. The fea…
Magnetic resonance imaging (MRI) is routinely used for brain tumor diagnosis, treatment planning, and post-treatment surveillance. Recently, various models based on deep neural networks have been proposed for the pixel-level segmentation of tumors in brain MRIs. However, the structural variations, spatial dissimilarities, and intensity inhomogeneity in MRIs make segmentation a challenging task. We propose a new end-to-end brain tumor segmentation architecture based on U-Net that integrates Inception modules and dilated convolutions into its contracting and expanding paths. This allows us to ex…
Brain Tumor Classification From MRI Images Using Machine Learning
针对脑肿瘤早期检测与分类的临床需求，本项目提出开发基于集成学习的机器学习预测系统，用于从MRI图像中定位并分类脑肿瘤，助力精准诊断与治疗规划。
In the past few years, deep learning (DL) models have drawn great attention and shown superior performance on brain tumor and subregion segmentation tasks. However, the success is limited to segmentation of adult gliomas, where sufficient data have been collected, manually labeled, and published for training DL models. It is still challenging to segment pediatric tumors, because the appearances are different from adult gliomas. Hence, directly applying a pretained DL model on pediatric data usually generates unacceptable results. Because pediatric data is very limited, both labeled and unlabel…
In this paper, a convolutional neural network (CNN) was used to classify NMR images of human brains with 4 different types of tumors: meningioma, glioma and pituitary gland tumors. During the training phase of this project, an accuracy of 100% was obtained, meanwhile, in the evaluation phase the precision was 96%.
Automatic brain tumor segmentation from Magnetic Resonance Imaging (MRI) data plays an important role in assessing tumor response to therapy and personalized treatment stratification.Manual segmentation is tedious and subjective.Deep-learning-based algorithms for brain tumor segmentation have the potential to provide objective and fast tumor segmentation.However, the training of such algorithms requires large datasets which are not always available. Data augmentation techniques may reduce the need for large datasets.However current approaches are mostly parametric and may result in suboptimal …
Generative models have been very successful over the years and have received significant attention for synthetic data generation. As deep learning models are getting more and more complex, they require large amounts of data to perform accurately. In medical image analysis, such generative models play a crucial role as the available data is limited due to challenges related to data privacy, lack of data diversity, or uneven data distributions. In this paper, we present a method to generate brain tumor MRI images using generative adversarial networks. We have utilized StyleGAN2 with ADA methodol…
Deep learning methods for brain tumor segmentation are typically trained in an ad hoc fashion on all available data. Brain tumors are tremendously heterogeneous in image appearance and labeled training data is limited. We argue that incorporation of additional prior information, specifically tumor grade, associated with tumor imaging phenotypes during model training can significantly improve segmentation performance. Two strategies for incorporation of tumor grade during model training are proposed and their impact on segmentation performance is demonstrated on the BRATS 2018 dataset.
Brain tumor segmentation is a challenging problem in medical image analysis. The endpoint is to generate the salient masks that accurately identify brain tumor regions in an fMRI screening. In this paper, we propose a novel attention gate (AG model) for brain tumor segmentation that utilizes both the edge detecting unit and the attention gated network to highlight and segment the salient regions from fMRI images. This feature enables us to eliminate the necessity of having to explicitly point towards the damaged area(external tissue localization) and classify(classification) as per classical c…
Hybrid Multihead Attentive Unet-3D for Brain Tumor Segmentation
本文提出一种混合多头注意力U-Net架构，用于提高脑肿瘤分割的准确性，在BraTS 2020数据集上优于SegNet、FCN-8s和Dense121 U-Net。
Glioma is the most deadly brain tumor with high mortality. Treatment planning by human experts depends on the proper diagnosis of physical symptoms along with Magnetic Resonance(MR) image analysis. Highly variability of a brain tumor in terms of size, shape, location, and a high volume of MR images makes the analysis time-consuming. Automatic segmentation methods achieve a reduction in time with excellent reproducible results. The article aims to survey the advancement of automated methods for Glioma brain tumor segmentation. It is also essential to make an objective evaluation of various mode…
The growth of abnormal cells in the brain's tissue causes brain tumors. Brain tumors are considered one of the most dangerous disorders in children and adults. It develops quickly, and the patient's survival prospects are slim if not appropriately treated. Proper treatment planning and precise diagnoses are essential to improving a patient's life expectancy. Brain tumors are mainly diagnosed using magnetic resonance imaging (MRI). As part of a convolution neural network (CNN)-based illustration, an architecture containing five convolution layers, five max-pooling layers, a Flatten layer, and t…
Multimodal brain tumor segmentation challenge (BraTS) brings together researchers to improve automated methods for 3D MRI brain tumor segmentation. Tumor segmentation is one of the fundamental vision tasks necessary for diagnosis and treatment planning of the disease. Previous years winning methods were all deep-learning based, thanks to the advent of modern GPUs, which allow fast optimization of deep convolutional neural network architectures. In this work, we explore best practices of 3D semantic segmentation, including conventional encoder-decoder architecture, as well combined loss functio…
Brain tumor multi classification and segmentation in MRI images using deep learning
本研究提出基于EfficientNetB1的分类模型和基于U-Net的分割模型，用于MRI图像中脑肿瘤的四分类与准确分割，实验表明其高准确率具有临床应用潜力。
Diagnosing Brain Tumor with the aid of Magnetic Resonance Imaging (MRI) has gained enormous prominence over the years, primarily in the field of medical science. Detection and/or partitioning of brain tumors solely with the aid of MR imaging is achieved at the cost of immense time and effort and demands a lot of expertise from engaged personnel. This substantiates the necessity of fabricating an autonomous model brain tumor diagnosis. Our work involves implementing a deep convolutional neural network (DCNN) for diagnosing brain tumors from MR images. The dataset used in this paper consists of …
Brain tumor segmentation from magnetic resonance imaging (MRI) plays an important role in diagnostic radiology. To overcome the practical issues in manual approaches, there is a huge demand for building automatic tumor segmentation algorithms. This work introduces an efficient brain tumor summation model by exploiting the advancement in MRI and graph neural networks (GNNs). The model represents the volumetric MRI as a region adjacency graph (RAG) and learns to identify the type of tumors through a graph attention network (GAT) -- a variant of GNNs. The ablation analysis conducted on two benchm…
Fully Automated Tumor Segmentation for Brain MRI data using Multiplanner UNet
本文评估了多平面U-Net（MPUnet）在PED、MET和SSA三个脑肿瘤数据集上的分割性能，发现肿瘤核心分割精度较高，而水肿和增强肿瘤区域分割存在变异性，表明该方法仍需进一步改进并纳入更多MRI数据。
Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In this regard, a novel two-phase deep learning-based framework is proposed to detect and categorize brain tumors in magnetic resonance images (MRIs). In the first phase, a novel deep boosted features and ensemble classifiers (DBF-EC) scheme is proposed to detect tumor MRI images from healthy individuals effectively. The deep boosted feature space is achieved t…
Unified HT-CNNs Architecture: Transfer Learning for Segmenting Diverse Brain Tumors in MRI from Gliomas to Pediatric Tumors
本文提出统一迁移学习架构HT-CNNs，通过集成混合Transformer与卷积神经网络并结合迁移学习，在多种脑肿瘤MRI分割任务上超越BraTS以往获胜方法，为医学图像分割及临床应用提供新方案。
Detecting Glioma, Meningioma, and Pituitary Tumors, and Normal Brain Tissues based on Yolov11 and Yolov8 Deep Learning Models
本文提出基于YoloV11和YoloV8深度学习模型及迁移学习微调的AI驱动方法，在CE-MRI Figshare数据集上实现胶质瘤、脑膜瘤、垂体瘤及正常脑组织的高精度四分类检测。
Brain tumor segmentation from Magnetic Resonance Images (MRIs) is an important task to measure tumor responses to treatments. However, automatic segmentation is very challenging. This paper presents an automatic brain tumor segmentation method based on a Normalized Gaussian Bayesian classification and a new 3D Fluid Vector Flow (FVF) algorithm. In our method, a Normalized Gaussian Mixture Model (NGMM) is proposed and used to model the healthy brain tissues. Gaussian Bayesian Classifier is exploited to acquire a Gaussian Bayesian Brain Map (GBBM) from the test brain MR images. GBBM is further p…
Brain tumor detection can make the difference between life and death. Recently, deep learning-based brain tumor detection techniques have gained attention due to their higher performance. However, obtaining the expected performance of such deep learning-based systems requires large amounts of classified images to train the deep models. Obtaining such data is usually boring, time-consuming, and can easily be exposed to human mistakes which hinder the utilization of such deep learning approaches. This paper introduces a novel framework for brain tumor detection and classification. The basic idea…
We propose a novel, simple and effective method to integrate lesion prior and a 3D U-Net for improving brain tumor segmentation. First, we utilize the ground-truth brain tumor lesions from a group of patients to generate the heatmaps of different types of lesions. These heatmaps are used to create the volume-of-interest (VOI) map which contains prior information about brain tumor lesions. The VOI map is then integrated with the multimodal MR images and input to a 3D U-Net for segmentation. The proposed method is evaluated on a public benchmark dataset, and the experimental results show that th…
Non-invasive techniques such as magnetic resonance imaging (MRI) are widely employed in brain tumor diagnostics. However, manual segmentation of brain tumors from 3D MRI volumes is a time-consuming task that requires trained expert radiologists. Due to the subjectivity of manual segmentation, there is low inter-rater reliability which can result in diagnostic discrepancies. As the success of many brain tumor treatments depends on early intervention, early detection is paramount. In this context, a fully automated segmentation method for brain tumor segmentation is necessary as an efficient and…
This paper proposes a novel cascaded U-Net for brain tumor segmentation. Inspired by the distinct hierarchical structure of brain tumor, we design a cascaded deep network framework, in which the whole tumor is segmented firstly and then the tumor internal substructures are further segmented. Considering that the increase of the network depth brought by cascade structures leads to a loss of accurate localization information in deeper layers, we construct many skip connections to link features at the same resolution and transmit detailed information from shallow layers to the deeper layers. Then…
The brain is a complex organ controlling cognitive process and physical functions. Tumors in the brain are accelerated cell growths affecting the normal function and processes in the brain. MRI scans provides detailed images of the body being one of the most common tests to diagnose brain tumors. The process of segmentation of brain tumors from magnetic resonance imaging can provide a valuable guide for diagnosis, treatment planning and prediction of results. Here we consider the problem brain tumor segmentation using a Deep learning architecture for use in tumor segmentation. Although the pro…
Automatic brain tumor segmentation in 2D intra-operative ultrasound images using magnetic resonance imaging tumor annotations
本文提出利用更易获取的MRI肿瘤标注，通过图像配准转移至iUS图像来训练nnU-Net模型，实现术中超声脑肿瘤自动分割，其效果与iUS标注训练的模型相当。
Detection and Classification of Glioblastoma Brain Tumor
本文提出 UNet 和 Deeplabv3 两种深度学习模型用于胶质母细胞瘤脑肿瘤的检测与分割，实验表明两者均能准确分割，且 Deeplabv3 准确率更高但计算开销更大，为临床早期治疗提供了有效辅助方法。
Automatic MRI brain tumor segmentation is of vital importance for the disease diagnosis, monitoring, and treatment planning. In this paper, we propose a two-stage encoder-decoder based model for brain tumor subregional segmentation. Variational autoencoder regularization is utilized in both stages to prevent the overfitting issue. The second-stage network adopts attention gates and is trained additionally using an expanded dataset formed by the first-stage outputs. On the BraTS 2020 validation dataset, the proposed method achieves the mean Dice score of 0.9041, 0.8350, and 0.7958, and Hausdorf…
Brain tumor classification is crucial for clinical analysis and an effective treatment plan to cure patients. Deep learning models help radiologists to accurately and efficiently analyze tumors without manual intervention. However, brain tumor analysis is challenging because of its complex structure, texture, size, location, and appearance. Therefore, a novel deep residual and regional-based Res-BRNet Convolutional Neural Network (CNN) is developed for effective brain tumor (Magnetic Resonance Imaging) MRI classification. The developed Res-BRNet employed Regional and boundary-based operations …
Tumor Location-weighted MRI-Report Contrastive Learning: A Framework for Improving the Explainability of Pediatric Brain Tumor Diagnosis
针对卷积神经网络在脑肿瘤MRI诊断中可解释性不足的问题，提出整合肿瘤位置的MRI-放射报告对比学习框架，提升了儿童低级别胶质瘤基因标记分类的性能与可解释性。
Accurate intraoperative diagnosis is essential for providing safe and effective care during brain tumor surgery. Our standard-of-care diagnostic methods are time, resource, and labor intensive, which restricts access to optimal surgical treatments. To address these limitations, we propose an alternative workflow that combines stimulated Raman histology (SRH), a rapid optical imaging method, with deep learning-based automated interpretation of SRH images for intraoperative brain tumor diagnosis and real-time surgical decision support. Here, we present OpenSRH, the first public dataset of clinic…
Deep Learning is the newest and the current trend of the machine learning field that paid a lot of the researchers' attention in the recent few years. As a proven powerful machine learning tool, deep learning was widely used in several applications for solving various complex problems that require extremely high accuracy and sensitivity, particularly in the medical field. In general, brain tumor is one of the most common and aggressive malignant tumor diseases which is leading to a very short expected life if it is diagnosed at higher grade. Based on that, brain tumor grading is a very critica…
Automated brain tumor segmentation plays an important role in the diagnosis and prognosis of the patient. In addition, features from the tumorous brain help in predicting patients overall survival. The main focus of this paper is to segment tumor from BRATS 2018 benchmark dataset and use age, shape and volumetric features to predict overall survival of patients. The random forest classifier achieves overall survival accuracy of 59% on the test dataset and 67% on the dataset with resection status as gross total resection. The proposed approach uses fewer features but achieves better accuracy th…
Learning to Learn Unlearned Feature for Brain Tumor Segmentation
提出基于主动学习和元学习的微调算法，仅需少量样本即可在高级别胶质瘤到脑转移瘤的迁移学习中实现领域参数平衡，防止遗忘原始任务。
A Biophysically-Conditioned Generative Framework for 3D Brain Tumor MRI Synthesis
本文提出了一种基于生物物理条件的生成框架，用于生成高保真的3D脑肿瘤MRI，通过条件生成模型实现肿瘤合成和健康组织修复，实验结果显示在PSNR指标上取得良好效果。
In brain tumor diagnosis and surgical planning, segmentation of tumor regions and accurate analysis of surrounding normal tissues are necessary for physicians. Pathological variability often renders difficulty to register a well-labeled normal atlas to such images and to automatic segment/label surrounding normal brain tissues. In this paper, we propose a new registration approach that first segments brain tumor using a U-Net and then simulates missed normal tissues within the tumor region using a partial convolutional network. Then, a standard normal brain atlas image is registered onto such …
Multi-modal magnetic resonance imaging (MRI) is a crucial method for analyzing the human brain. It is usually used for diagnosing diseases and for making valuable decisions regarding the treatments - for instance, checking for gliomas in the human brain. With varying degrees of severity and detection, properly diagnosing gliomas is one of the most daunting and significant analysis tasks in modern-day medicine. Our primary focus is on working with different approaches to perform the segmentation of brain tumors in multimodal MRI scans. Now, the quantity, variability of the data used for trainin…
Accurate detection of brain tumors could save lots of lives and increasing the accuracy of this binary classification even as much as a few percent has high importance. Neural Gas Networks (NGN) is a fast, unsupervised algorithm that could be used in data clustering, image pattern recognition, and image segmentation. In this research, we used the metaheuristic Firefly Algorithm (FA) for image contrast enhancement as pre-processing and NGN weights for feature extraction and segmentation of Magnetic Resonance Imaging (MRI) data on two brain tumor datasets from the Kaggle platform. Also, tumor cl…
Prototype-Driven and Multi-Expert Integrated Multi-Modal MR Brain Tumor Image Segmentation
针对多模态MR脑肿瘤分割中肿瘤子区域信息混叠、单区域特征未被强化的问题，提出原型驱动结合多专家集成的分割方法，通过模态互传获取完整原型、原型激活强化子区域特征、多专家融合多层特征，在三个竞赛数据集上验证了方法优越性。
We present a joint graph convolution-image convolution neural network as our submission to the Brain Tumor Segmentation (BraTS) 2021 challenge. We model each brain as a graph composed of distinct image regions, which is initially segmented by a graph neural network (GNN). Subsequently, the tumorous volume identified by the GNN is further refined by a simple (voxel) convolutional neural network (CNN), which produces the final segmentation. This approach captures both global brain feature interactions via the graphical representation and local image details through the use of convolutional filte…
Brain Tumor Detection using Convolutional Neural Networks with Skip Connections
该研究面向MRI脑肿瘤良恶性分类，比较加宽、加深及跳跃连接等CNN优化方式，证明合理组合可超越基线模型。
Glioma, the malignant brain tumor, requires immediate treatment to improve the survival of patients. Gliomas heterogeneous nature makes the segmentation difficult, especially for sub-regions like necrosis, enhancing tumor, non-enhancing tumor, and Edema. Deep neural networks like full convolution neural networks and ensemble of fully convolution neural networks are successful for Glioma segmentation. The paper demonstrates the use of a 3D fully convolution neural network with a three layer encoder decoder approach for layer arrangement. The encoder blocks include the dense modules, and decoder…
Convolutional Neural Networks (CNNs) have demonstrated state-of-the-art performance in medical image segmentation tasks. A common feature in most top-performing CNNs is an encoder-decoder architecture inspired by the U-Net. For multi-region brain tumor segmentation, 3D U-Net architecture and its variants provide the most competitive segmentation performances. In this work, we propose an interesting extension of the standard 3D U-Net architecture, specialized for brain tumor segmentation. The proposed network, called E1D3 U-Net, is a one-encoder, three-decoder fully-convolutional neural network…
In the clinical diagnosis and treatment of brain tumors, manual image reading consumes a lot of energy and time. In recent years, the automatic tumor classification technology based on deep learning has entered people's field of vision. Brain tumors can be divided into primary and secondary intracranial tumors according to their source. However, to our best knowledge, most existing research on brain tumors are limited to primary intracranial tumor images and cannot classify the source of the tumor. In order to solve the task of tumor source type classification, we analyze the existing technolo…
Brain tumor analysis in MRI images is a significant and challenging issue because misdiagnosis can lead to death. Diagnosis and evaluation of brain tumors in the early stages increase the probability of successful treatment. However, the complexity and variety of tumors, shapes, and locations make their segmentation and classification complex. In this regard, numerous researchers have proposed brain tumor segmentation and classification methods. This paper presents an approach that simultaneously segments and classifies brain tumors in MRI images using a framework that contains MRI image enhan…
The brain tumor is the most aggressive kind of tumor and can cause low life expectancy if diagnosed at the later stages. Manual identification of brain tumors is tedious and prone to errors. Misdiagnosis can lead to false treatment and thus reduce the chances of survival for the patient. Medical resonance imaging (MRI) is the conventional method used to diagnose brain tumors and their types. This paper attempts to eliminate the manual process from the diagnosis process and use machine learning instead. We proposed the use of pretrained convolutional neural networks (CNN) for the diagnosis and …
We propose an optimized U-Net architecture for a brain tumor segmentation task in the BraTS21 challenge. To find the optimal model architecture and the learning schedule, we have run an extensive ablation study to test: deep supervision loss, Focal loss, decoder attention, drop block, and residual connections. Additionally, we have searched for the optimal depth of the U-Net encoder, number of convolutional channels and post-processing strategy. Our method won the validation phase and took third place in the test phase. We have open-sourced the code to reproduce our BraTS21 submission at the N…
Segment Anything Model for Brain Tumor Segmentation
本研究针对脑肿瘤精准分割的临床需求，评估了零样本图像分割基础模型SAM在脑肿瘤分割任务上的性能，发现未微调的SAM与当前SOTA模型仍有差距。
Automatic segmentation of glioma and its subregions is of great significance for diagnosis, treatment and monitoring of disease. In this paper, an augmentation method, called TensorMixup, was proposed and applied to the three dimensional U-Net architecture for brain tumor segmentation. The main ideas included that first, two image patches with size of 128 in three dimensions were selected according to glioma information of ground truth labels from the magnetic resonance imaging data of any two patients with the same modality. Next, a tensor in which all elements were independently sampled from…
Brain Tumor Detection Using Deep Learning Approaches
本研究比较 VGG16、VGG19、DenseNet121、ResNet50 和 YOLO V4 五种迁移学习模型在 MRI 脑肿瘤检测中的表现，发现 ResNet50 准确率最高，达 99.54%，为自动化脑肿瘤检测提供了参考。
An Optimization Framework for Processing and Transfer Learning for the Brain Tumor Segmentation
针对脑肿瘤分割的准确性与泛化性不足，提出基于3D U-Net的优化框架，结合预处理、后处理与迁移学习，在BraTS 2023三个挑战验证集上取得0.79、0.72、0.74的Dice分数。
Attention-Enhanced Hybrid Feature Aggregation Network for 3D Brain Tumor Segmentation
本文提出GLIMS模型，通过多尺度特征提取、Swin Transformer和注意力引导解码器实现3D脑肿瘤分割，在BraTS验证集上取得高Dice分数。
Gliomas are among the most aggressive and deadly brain tumors. This paper details the proposed Deep Neural Network architecture for brain tumor segmentation from Magnetic Resonance Images. The architecture consists of a cascade of three Deep Layer Aggregation neural networks, where each stage elaborates the response using the feature maps and the probabilities of the previous stage, and the MRI channels as inputs. The neuroimaging data are part of the publicly available Brain Tumor Segmentation (BraTS) 2020 challenge dataset, where we evaluated our proposal in the BraTS 2020 Validation and Tes…
According to the World Health Organization (WHO), cancer is the second leading cause of death worldwide, responsible for over 9.5 million deaths in 2018 alone. Brain tumors count for one out of every four cancer deaths. Therefore, accurate and timely diagnosis of brain tumors will lead to more effective treatments. Physicians classify brain tumors only with biopsy operation by brain surgery, and after diagnosing the type of tumor, a treatment plan is considered for the patient. Automatic systems based on machine learning algorithms can allow physicians to diagnose brain tumors with noninvasive…
Brain tumor segmentation is highly contributive in diagnosing and treatment planning. The manual brain tumor delineation is a time-consuming and tedious task and varies depending on the radiologists skill. Automated brain tumor segmentation is of high importance, and does not depend on either inter or intra-observation. The objective of this study is to automate the delineation of brain tumors from the FLAIR, T1 weighted, T2 weighted, and T1 weighted contrast-enhanced MR sequences through a deep learning approach, with a focus on determining which MR sequence alone or which combination thereof…
Brain tumor segmentation plays an essential role in medical image analysis. In recent studies, deep convolution neural networks (DCNNs) are extremely powerful to tackle tumor segmentation tasks. We propose in this paper a novel training method that enhances the segmentation results by adding an additional classification branch to the network. The whole network was trained end-to-end on the Multimodal Brain Tumor Segmentation Challenge (BraTS) 2020 training dataset. On the BraTS's validation set, it achieved an average Dice score of 78.43%, 89.99%, and 84.22% respectively for the enhancing tumo…
Past few years have witnessed the prevalence of deep learning in many application scenarios, among which is medical image processing. Diagnosis and treatment of brain tumors requires an accurate and reliable segmentation of brain tumors as a prerequisite. However, such work conventionally requires brain surgeons significant amount of time. Computer vision techniques could provide surgeons a relief from the tedious marking procedure. In this paper, a 3D U-net based deep learning model has been trained with the help of brain-wise normalization and patching strategies for the brain tumor segmenta…
Promptable Counterfactual Diffusion Model for Unified Brain Tumor Segmentation and Generation with MRIs
提出可提示反事实扩散模型，统一脑肿瘤MRI分割与生成，通过掩码级提示实现双向推理，在BRATS2021上分割性能显著优于传统方法。
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