Graz University of Technology（格拉茨工业大学）；University Medical Center Göttingen（哥廷根大学医学中心）；German Centre for Cardiovascular Research (DZHK)（德国心血管研究中心）；University of Göttingen（哥廷根大学）；BioTechMed-Graz
Moritz Blumenthal, Guanxiong Luo, Martin Schilling, H. Christian M. Holme, Martin Uecker
Purpose: To develop a deep-learning-based image reconstruction framework for reproducible research in MRI.
Methods: The BART toolbox offers a rich set of implementations of calibration and reconstruction algorithms for parallel imaging and compressed sensing. In this work, BART was extended by a non-linear operator framework that provides automatic differentiation to allow computation of gradients. Existing MRI-specific operators of BART, such as the non-uniform fast Fourier transform, are directly integrated into this framework and are complemented by common building blocks used in neural networks. To evaluate the use of the framework for advanced deep-learning-based reconstruction, two state-of-the-art unrolled reconstruction networks, namely the Variational Network [1] and MoDL [2], were implemented.
Results: State-of-the-art deep image-reconstruction networks can be constructed and trained using BART's gradient based optimization algorithms. The BART implementation achieves a similar performance in terms of training time and reconstruction quality compared to the original implementations based on TensorFlow.
Conclusion: By integrating non-linear operators and neural networks into BART, we provide a general framework for deep-learning-based reconstruction in MRI.
Purpose: To develop a deep learning-based Bayesian inference for MRI reconstruction. Methods: We modeled the MRI reconstruction problem with Bayes's theorem, following the recently proposed PixelCNN++ method. The image reconstruction from incomplete k-space measurement was obtained by maximizing the posterior possibility. A generative network was utilized as the image prior, which was computationally tractable, and the k-space data fidelity was enforced by using an equality constraint. The stochastic backpropagation was utilized to calculate the descent gradient in the process of maximum a pos…
Beijing-Dublin International College（北京-都柏林国际学院）；University College Dublin（都柏林大学）
This technical report presents a comparative analysis of existing deep learning (DL) based approaches for brain tumor segmentation with missing MRI modalities. Approaches evaluated include the Adversarial Co-training Network (ACN) and a combination of mmGAN and DeepMedic. A more stable and easy-to-use version of mmGAN is also open-sourced at a GitHub repository. Using the BraTS2018 dataset, this work demonstrates that the state-of-the-art ACN performs better especially when T1c is missing. While a simple combination of mmGAN and DeepMedic also shows strong potentials when only one MRI modality…
The need for fast acquisition and automatic analysis of MRI data is growing in the age of big data. Although compressed sensing magnetic resonance imaging (CS-MRI) has been studied to accelerate MRI by reducing k-space measurements, in current CS-MRI techniques MRI applications such as segmentation are overlooked when doing image reconstruction. In this paper, we test the utility of CS-MRI methods in automatic segmentation models and propose a unified deep neural network architecture called SegNetMRI which we apply to the combined CS-MRI reconstruction and segmentation problem. SegNetMRI is bu…
Dalian University of Technology（大连理工大学）；Guilin University of Electronic Technology（桂林电子科技大学）
Magnetic Resonance Imaging (MRI) is one of the most dynamic and safe imaging techniques available for clinical applications. However, the rather slow speed of MRI acquisitions limits the patient throughput and potential indi cations. Compressive Sensing (CS) has proven to be an efficient technique for accelerating MRI acquisition. The most widely used CS-MRI model, founded on the premise of reconstructing an image from an incompletely filled k-space, leads to an ill-posed inverse problem. In the past years, lots of efforts have been made to efficiently optimize the CS-MRI model. Inspired by de…
Computational Radiology Laboratory, Boston Children’s Hospital（波士顿儿童医院计算放射实验室）；Harvard Medical School（哈佛医学院）
Fast data acquisition in Magnetic Resonance Imaging (MRI) is vastly in demand and scan time directly depends on the number of acquired k-space samples. Recently, the deep learning-based MRI reconstruction techniques were suggested to accelerate MR image acquisition. The most common issues in any deep learning-based MRI reconstruction approaches are generalizability and transferability. For different MRI scanner configurations using these approaches, the network must be trained from scratch every time with new training dataset, acquired under new configurations, to be able to provide good recon…
Sun Yat-Sen University（中山大学）；University of Edinburgh（爱丁堡大学）；Cardiovascular Research Centre, Royal Brompton Hospital（皇家布朗普顿医院心血管研究中心）；National Heart & Lung Institute, Imperial College London（帝国理工学院国家心肺研究所）
The performance of traditional compressive sensing-based MRI (CS-MRI) reconstruction is affected by its slow iterative procedure and noise-induced artefacts. Although many deep learning-based CS-MRI methods have been proposed to mitigate the problems of traditional methods, they have not been able to achieve more robust results at higher acceleration factors. Most of the deep learning-based CS-MRI methods still can not fully mine the information from the k-space, which leads to unsatisfactory results in the MRI reconstruction. In this study, we propose a new deep learning-based CS-MRI reconstr…
Compressed sensing for magnetic resonance imaging (CS-MRI) exploits image sparsity properties to reconstruct MRI from very few Fourier k-space measurements. The goal is to minimize any structural errors in the reconstruction that could have a negative impact on its diagnostic quality. To this end, we propose a deep error correction network (DECN) for CS-MRI. The DECN model consists of three parts, which we refer to as modules: a guide, or template, module, an error correction module, and a data fidelity module. Existing CS-MRI algorithms can serve as the template module for guiding the reconst…
Generative Adversarial Neural Networks (GANs) are applied to the synthetic generation of prostate lesion MRI images. GANs have been applied to a variety of natural images, is shown show that the same techniques can be used in the medical domain to create realistic looking synthetic lesion images. 16mm x 16mm patches are extracted from 330 MRI scans from the SPIE ProstateX Challenge 2016 and used to train a Deep Convolutional Generative Adversarial Neural Network (DCGAN) utilizing cutting edge techniques. Synthetic outputs are compared to real images and the implicit latent representations indu…
Compressed sensing MRI is a classic inverse problem in the field of computational imaging, accelerating the MR imaging by measuring less k-space data. The deep neural network models provide the stronger representation ability and faster reconstruction compared with "shallow" optimization-based methods. However, in the existing deep-based CS-MRI models, the high-level semantic supervision information from massive segmentation-labels in MRI dataset is overlooked. In this paper, we proposed a segmentation-aware deep fusion network called SADFN for compressed sensing MRI. The multilayer feature ag…
In multi-contrast magnetic resonance imaging (MRI), compressed sensing theory can accelerate imaging by sampling fewer measurements within each contrast. The conventional optimization-based models suffer several limitations: strict assumption of shared sparse support, time-consuming optimization and "shallow" models with difficulties in encoding the rich patterns hiding in massive MRI data. In this paper, we propose the first deep learning model for multi-contrast MRI reconstruction. We achieve information sharing through feature sharing units, which significantly reduces the number of paramet…
In most medical image processing tasks, the orientation of an image would affect computing result. However, manually reorienting images wastes time and effort. In this paper, we study the problem of recognizing orientation in cardiac MRI and using deep neural network to solve this problem. For multiple sequences and modalities of MRI, we propose a transfer learning strategy, which adapts our proposed model from a single modality to multiple modalities. We also propose a prediction method that uses voting. The results shows that deep neural network is an effective way in recognition of cardiac …
We propose a 2D Encoder-Decoder based deep learning architecture for semantic segmentation, that incorporates anatomical priors by imitating the encoder component of an autoencoder in latent space. The autoencoder is additionally enhanced by means of hierarchical features, extracted by an U-Net module. Our suggested architecture is trained in an end-to-end manner and is evaluated on the example of pelvic bone segmentation in MRI. A comparison to the standard U-Net architecture shows promising improvements.
For several years, numerous attempts have been made to reduce noise and artifacts in MRI. Although there have been many successful methods to address these problems, practical implementation for clinical images is still challenging because of its complicated mechanism. Recently, deep learning received considerable attention, emerging as a machine learning approach in delivering robust MR image processing. The purpose here is therefore to explore further and review noise and artifact reduction using deep learning for MRI.
Harvard Medical School（哈佛医学院）；Boston Children’s Hospital（波士顿儿童医院）
Fast data acquisition in Magnetic Resonance Imaging (MRI) is vastly in demand and scan time directly depends on the number of acquired k-space samples. Conventional MRI reconstruction methods for fast MRI acquisition mostly relied on different regularizers which represent analytical models of sparsity. However, recent data-driven methods based on deep learning has resulted in promising improvements in image reconstruction algorithms. In this paper, we propose a deep plug-and-play prior framework for parallel MRI reconstruction problems which utilize a deep neural network (DNN) as an advanced d…
Shanghai Starriver Bilingual School（上海星河湾双语学校）；University of California, Los Angeles（加利福尼亚大学洛杉矶分校）
Magnetic Resonance Imaging (MRI) is important in clinic to produce high resolution images for diagnosis, but its acquisition time is long for high resolution images. Deep learning based MRI super resolution methods can reduce scan time without complicated sequence programming, but may create additional artifacts due to the discrepancy between training data and testing data. Data consistency layer can improve the deep learning results but needs raw k-space data. In this work, we propose a magnitude-image based data consistency deep learning MRI super resolution method to improve super resolutio…
Technical University of Munich（慕尼黑工业大学）；Ludwig-Maximilians-University Munich（慕尼黑路德维希-马克西米利安大学）
The reconstruction of cortical surfaces from brain magnetic resonance imaging (MRI) scans is essential for quantitative analyses of cortical thickness and sulcal morphology. Although traditional and deep learning-based algorithmic pipelines exist for this purpose, they have two major drawbacks: lengthy runtimes of multiple hours (traditional) or intricate post-processing, such as mesh extraction and topology correction (deep learning-based). In this work, we address both of these issues and propose Vox2Cortex, a deep learning-based algorithm that directly yields topologically correct, three-di…
Compressed sensing (CS) is an efficient method to reconstruct MR image from small sampled data in $k$-space and accelerate the acquisition of MRI. In this work, we propose a novel deep geometric distillation network which combines the merits of model-based and deep learning-based CS-MRI methods, it can be theoretically guaranteed to improve geometric texture details of a linear reconstruction. Firstly, we unfold the model-based CS-MRI optimization problem into two sub-problems that consist of image linear approximation and image geometric compensation. Secondly, geometric compensation sub-prob…
Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University（复旦大学类脑智能科学与技术研究院）
In this paper, the problem of orientation correction in cardiac MRI images is investigated and a framework for orientation recognition via deep neural networks is proposed. For multi-modality MRI, we introduce a transfer learning strategy to transfer our proposed model from single modality to multi-modality. We embed the proposed network into the orientation correction command-line tool, which can implement orientation correction on 2D DICOM and 3D NIFTI images. Our source code, network models and tools are available at https://github.com/Jy-stdio/MSCMR_orient/
Compressive sensing (CS) is an effective approach for fast Magnetic Resonance Imaging (MRI). It aims at reconstructing MR images from a small number of under-sampled data in k-space, and accelerating the data acquisition in MRI. To improve the current MRI system in reconstruction accuracy and speed, in this paper, we propose two novel deep architectures, dubbed ADMM-Nets in basic and generalized versions. ADMM-Nets are defined over data flow graphs, which are derived from the iterative procedures in Alternating Direction Method of Multipliers (ADMM) algorithm for optimizing a general CS-based …
United Imaging Intelligence（联影智能）；UIH America, Inc.（联影美国公司）；United Imaging Healthcare（联影医疗）
Retrospectively gated cine (retro-cine) MRI is the clinical standard for cardiac functional analysis. Deep learning (DL) based methods have been proposed for the reconstruction of highly undersampled MRI data and show superior image quality and magnitude faster reconstruction time than CS-based methods. Nevertheless, it remains unclear whether DL reconstruction is suitable for cardiac function analysis. To address this question, in this study we evaluate and compare the cardiac functional values (EDV, ESV and EF for LV and RV, respectively) obtained from highly accelerated MRI acquisition usin…
Facebook AI Research（Facebook人工智能研究）；fastMRI team（fastMRI团队）
Deep learning approaches to accelerated MRI take a matrix of sampled Fourier-space lines as input and produce a spatial image as output. In this work we show that by careful choice of the offset used in the sampling procedure, the symmetries in k-space can be better exploited, producing higher quality reconstructions than given by standard equally-spaced samples or randomized samples motivated by compressed sensing.
Open-Source Manually Annotated Vocal Tract Database for Automatic Segmentation from 3D MRI Using Deep Learning: Benchmarking 2D and 3D Convolutional and Transformer Networks
University of Iowa（爱荷华大学）；Shenandoah University（谢南多厄大学）
We introduce a model-based reconstruction framework with deep learned (DL) and smoothness regularization on manifolds (STORM) priors to recover free breathing and ungated (FBU) cardiac MRI from highly undersampled measurements. The DL priors enable us to exploit the local correlations, while the STORM prior enables us to make use of the extensive non-local similarities that are subject dependent. We introduce a novel model-based formulation that allows the seamless integration of deep learning methods with available prior information, which current deep learning algorithms are not capable of. …
Fast data acquisition in Magnetic Resonance Imaging (MRI) is vastly in demand and scan time directly depends on the number of acquired k-space samples. The data-driven methods based on deep neural networks have resulted in promising improvements, compared to the conventional methods, in image reconstruction algorithms. The connection between deep neural network and Ordinary Differential Equation (ODE) has been observed and studied recently. The studies show that different residual networks can be interpreted as Euler discretization of an ODE. In this paper, we propose an ODE-based deep network…
Image-based brain cancer prediction models, based on radiomics, quantify the radiologic phenotype from magnetic resonance imaging (MRI). However, these features are difficult to reproduce because of variability in acquisition and preprocessing pipelines. Despite evidence of intra-tumor phenotypic heterogeneity, the spatial diversity between different slices within an MRI scan has been relatively unexplored using such methods. In this work, we propose a deep anchor attention aggregation strategy with a Vision Transformer to predict survival risk for brain cancer patients. A Deep Anchor Attentio…
Paul C. Lauterbur Research Center for Biomedical Imaging（保罗·C·劳特伯生物医学成像研究中心）；Shenzhen College of Advanced Technology, University of Chinese Academy of Sciences（中国科学院大学深圳先进技术学院）；University at Buffalo, the State University of New York（纽约州立大学布法罗分校）
Image reconstruction from undersampled k-space data has been playing an important role for fast MRI. Recently, deep learning has demonstrated tremendous success in various fields and also shown potential to significantly speed up MR reconstruction with reduced measurements. This article gives an overview of deep learning-based image reconstruction methods for MRI. Three types of deep learning-based approaches are reviewed, the data-driven, model-driven and integrated approaches. The main structure of each network in three approaches is explained and the analysis of common parts of reviewed net…
The extent to which the arbitrarily selected L2 regularization hyperparameter value affects the outcome of semantic segmentation with deep learning is demonstrated. Demonstrations rely on training U-net on small LGE-MRI datasets using the arbitrarily selected L2 regularization values. The remaining hyperparameters are to be manually adjusted or tuned only when 10 % of all epochs are reached before the training validation accuracy reaches 90%. Semantic segmentation with deep learning outcomes are objectively and subjectively evaluated against the manual ground truth segmentation.
University of Florida（佛罗里达大学）；National Institutes of Health Clinical Center（国立卫生研究院临床中心）
Deep neural networks have demonstrated very promising performance on accurate segmentation of challenging organs (e.g., pancreas) in abdominal CT and MRI scans. The current deep learning approaches conduct pancreas segmentation by processing sequences of 2D image slices independently through deep, dense per-pixel masking for each image, without explicitly enforcing spatial consistency constraint on segmentation of successive slices. We propose a new convolutional/recurrent neural network architecture to address the contextual learning and segmentation consistency problem. A deep convolutional …
Benchmarking MRI Representations for Deep Learning-Based Focal Cortical Dysplasia Segmentation
The University of Queensland（昆士兰大学）；I-MED Radiology（I-MED放射学）；Bennett University（贝内特大学）；Indian Institute of Technology Madras（印度马德拉斯理工学院）；University College of Engineering, Osmania University（奥斯曼尼亚大学工程学院）；Mater Hospital（玛特医院）；Royal Brisbane and Women’s Hospital（皇家布里斯班和妇女医院）
University of Ottawa（渥太华大学）；Children’s Hospital of Eastern Ontario（东安大略儿童医院）
Polymicrogyria (PMG) is a disorder of cortical organization mainly seen in children, which can be associated with seizures, developmental delay and motor weakness. PMG is typically diagnosed on magnetic resonance imaging (MRI) but some cases can be challenging to detect even for experienced radiologists. In this study, we create an open pediatric MRI dataset (PPMR) with PMG and controls from the Children's Hospital of Eastern Ontario (CHEO), Ottawa, Canada. The differences between PMG MRIs and control MRIs are subtle and the true distribution of the features of the disease is unknown. This mak…
Center for Translational Research in Neuroimaging and Data Science (TReNDS)（神经影像与数据科学转化研究中心（TReNDS））
Deep learning has become a prominent computational modeling tool in the areas of computer vision and image processing in recent years. This research comprehensively analyzes the different deep-learning methods used for image-to-image translation and reconstruction in the natural and medical imaging domains. We examine the famous deep learning frameworks, such as convolutional neural networks and generative adversarial networks, and their variants, delving into the fundamental principles and difficulties of each. In the field of natural computer vision, we investigate the development and extens…
In this paper, we study the problem of imaging orientation in cardiac MRI, and propose a framework to categorize the orientation for recognition and standardization via deep neural networks. The method uses a new multi-tasking strategy, where both the tasks of cardiac segmentation and orientation recognition are simultaneously achieved. For multiple sequences and modalities of MRI, we propose a transfer learning strategy, which adapts our proposed model from a single modality to multiple modalities. We embed the orientation recognition network in a Cardiac MRI Orientation Adjust Tool, i.e., CM…
Evaluating ADC-only deep learning pipelines for breast cancer detection and segmentation using standalone diffusion-weighted MRI
University of Oviedo（奥维耶多大学）；University of A Coruña（拉科鲁尼亚大学）；The University of Texas at Austin（德克萨斯大学奥斯汀分校）；Purdue University（普渡大学）；Asturias Central University Hospital (HUCA)（阿斯图里亚斯中央大学医院）
Fiber orientation distribution (FOD) is an advanced diffusion MRI modeling technique that represents complex white matter fiber configurations, and a key step for subsequent brain tractography and connectome analysis. Its reliability and accuracy, however, heavily rely on the quality of the MRI acquisition and the subsequent estimation of the FODs at each voxel. Generating reliable FODs from widely available clinical protocols with single-shell and low-angular-resolution acquisitions remains challenging but could potentially be addressed with recent advances in deep learning-based enhancement …
Adhesions are an important cause of chronic pain following abdominal surgery. Recent developments in abdominal cine-MRI have enabled the non-invasive diagnosis of adhesions. Adhesions are identified on cine-MRI by the absence of sliding motion during movement. Diagnosis and mapping of adhesions improves the management of patients with pain. Detection of abdominal adhesions on cine-MRI is challenging from both a radiological and deep learning perspective. We focus on classifying presence or absence of adhesions in sagittal abdominal cine-MRI series. We experimented with spatio-temporal deep lea…
Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School（哈佛医学院麻省总医院Martinos生物医学影像中心）；Massachusetts Institute of Technology（麻省理工学院）；Cornell University（康奈尔大学）；University College London（伦敦大学学院）
Probabilistic atlas priors have been commonly used to derive adaptive and robust brain MRI segmentation algorithms. Widely-used neuroimage analysis pipelines rely heavily on these techniques, which are often computationally expensive. In contrast, there has been a recent surge of approaches that leverage deep learning to implement segmentation tools that are computationally efficient at test time. However, most of these strategies rely on learning from manually annotated images. These supervised deep learning methods are therefore sensitive to the intensity profiles in the training dataset. To…
Institute of Medical Technology and Intelligent Systems, Hamburg University of Technology（汉堡工业大学医疗技术与智能系统研究所）；jung diagnostics GmbH（jung diagnostics GmbH公司）；Hamburg University of Technology（汉堡工业大学）
Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD) in brain MRI with deep learning has shown promising results to provide a quick, initial assessment. So far, these methods only rely on the visual appearance of healthy brain anatomy for anomaly detection. Another biomarker for abnormal brain development is the deviation between the brain age and the chronological age, which is unexplored in combination with …
Segmentation of the left ventricle (LV) from cardiac magnetic resonance imaging (MRI) datasets is an essential step for calculation of clinical indices such as ventricular volume and ejection fraction. In this work, we employ deep learning algorithms combined with deformable models to develop and evaluate a fully automatic segmentation tool for the LV from short-axis cardiac MRI datasets. The method employs deep learning algorithms to learn the segmentation task from the ground true data. Convolutional networks are employed to automatically detect the LV chamber in MRI dataset. Stacked autoenc…
Technical University of Munich（慕尼黑工业大学）；D’Annunzio University（邓南遮大学）
Convolutional networks are successful, but they have recently been outperformed by new neural networks that are equivariant under rotations and translations. These new networks work better because they do not struggle with learning each possible orientation of each image feature separately. So far, they have been proposed for 2D and 3D data. Here we generalize them to 6D diffusion MRI data, ensuring joint equivariance under 3D roto-translations in image space and the matching 3D rotations in $q$-space, as dictated by the image formation. Such equivariant deep learning is appropriate for diffus…
Effective and accurate diagnosis of Alzheimer's disease (AD) or mild cognitive impairment (MCI) can be critical for early treatment and thus has attracted more and more attention nowadays. Since first introduced, machine learning methods have been gaining increasing popularity for AD related research. Among the various identified biomarkers, magnetic resonance imaging (MRI) are widely used for the prediction of AD or MCI. However, before a machine learning algorithm can be applied, image features need to be extracted to represent the MRI images. While good representations can be pivotal to the…
Technische Universität München（慕尼黑工业大学）；University of Edinburgh（爱丁堡大学）；University of Sheffield（谢菲尔德大学）
Dynamic contrast-enhanced (DCE) MRI is an evolving imaging technique that provides a quantitative measure of pharmacokinetic (PK) parameters in body tissues, in which series of T1-weighted images are collected following the administration of a paramagnetic contrast agent. Unfortunately, in many applications, conventional clinical DCE-MRI suffers from low spatiotemporal resolution and insufficient volume coverage. In this paper, we propose a novel deep learning based approach to directly estimate the PK parameters from undersampled DCE-MRI data. Specifically, we design a custom loss function wh…
BrainFusionNet: a deep learning and XAI model to understand local, global, and sequential features of MRI images for improved brain tumour detection
School of Mathematics, Physics and Computing, University of Southern Queensland（南方昆士兰大学数学、物理与计算学院）；School of Engineering, University of Southern Queensland（南方昆士兰大学工程学院）
MRI Super-Resolution with Deep Learning: A Comprehensive Survey
A. I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences, University of Eastern Finland（A.I.维塔内恩分子科学研究所，健康科学学院，东芬兰大学）；Harvard Medical School and Boston Children’s Hospital（哈佛医学院和波士顿儿童医院）；Department of Radiology, Technical University of Munich（医学影像学系，慕尼黑技术大学）；Department of Radiology, Massachusetts General Hospital（医学影像学系，麻省总医院）
To our knowledge, all deep computer-aided detection and diagnosis (CAD) systems for prostate cancer (PCa) detection consider bi-parametric magnetic resonance imaging (bp-MRI) only, including T2w and ADC sequences while excluding the 4D perfusion sequence,which is however part of standard clinical protocols for this diagnostic task. In this paper, we question strategies to integrate information from perfusion imaging in deep neural architectures. To do so, we evaluate several ways to encode the perfusion information in a U-Net like architecture, also considering early versus mid fusion strategi…
Institute of Medical Technology and Intelligent Systems, Hamburg University of Technology（汉堡工业大学医学技术与智能系统研究所）；jung diagnostics GmbH（jung diagnostics 有限公司）
Purpose. Brain Magnetic Resonance Images (MRIs) are essential for the diagnosis of neurological diseases. Recently, deep learning methods for unsupervised anomaly detection (UAD) have been proposed for the analysis of brain MRI. These methods rely on healthy brain MRIs and eliminate the requirement of pixel-wise annotated data compared to supervised deep learning. While a wide range of methods for UAD have been proposed, these methods are mostly 2D and only learn from MRI slices, disregarding that brain lesions are inherently 3D and the spatial context of MRI volumes remains unexploited. Metho…
Imperial College London（伦敦帝国理工学院）；City University London（伦敦城市大学）；University of Lincoln（林肯大学）；University College London（伦敦大学学院）
Fast Magnetic Resonance Imaging (MRI) is highly in demand for many clinical applications in order to reduce the scanning cost and improve the patient experience. This can also potentially increase the image quality by reducing the motion artefacts and contrast washout. However, once an image field of view and the desired resolution are chosen, the minimum scanning time is normally determined by the requirement of acquiring sufficient raw data to meet the Nyquist-Shannon sampling criteria. Compressive Sensing (CS) theory has been perfectly matched to the MRI scanning sequence design with much l…
Duke Kunshan University（昆山杜克大学）；Duke University（杜克大学）
We developed a deep ensemble learning model with a radiomics spatial encoding execution for improved glioma segmentation accuracy using multi-parametric MRI (mp-MRI). This model was developed using 369 glioma patients with a 4-modality mp-MRI protocol: T1, contrast-enhanced T1 (T1-Ce), T2, and FLAIR. In each modality volume, a 3D sliding kernel was implemented across the brain to capture image heterogeneity: fifty-six radiomic features were extracted within the kernel, resulting in a 4th order tensor. Each radiomic feature can then be encoded as a 3D image volume, namely a radiomic feature map…
