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arXiv 2202.03595eess.IVcs.CV
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使用大脑白质特征对健康受试者的年龄和性别进行建模和预测:一种深度学习方法

Model and predict age and sex in healthy subjects using brain white matter features: A deep learning approach

Glasgow College, University of Electronic Science and Technology of China(电子科技大学格拉斯哥学院);Brigham and Women's Hospital, Harvard Medical School(哈佛医学院布莱根妇女医院)

Hao He, Fan Zhang, Steve Pieper, Nikos Makris, Yogesh Rathi, William Wells, Lauren J. O'Donnell

摘要:

人类大脑的白质(WM)结构是科学界非常感兴趣的。弥散MRI为无创性描述脑WM结构提供了有力的工具。为了潜在地监测与年龄相关的变化和调查与性别相关的脑结构差异,在脑连接体与健康受试者的年龄和性别之间的映射上,我们提取基于纤维簇的扩散特征,并使用新型集成神经网络分类器预测性别和年龄。我们在人类连接组计划(HCP)的年轻成人数据集上进行了实验,结果表明,我们的模型在性别预测方面达到了94.82%的准确率,在年龄预测方面达到了2.51年的MAE。我们还表明,分数各向异性(FA)是最具预测性的性别,而纤维的数量是最具预测性的年龄和不同功能的组合可以提高模型的性能。

英文摘要:

The human brain's white matter (WM) structure is of immense interest to the scientific community. Diffusion MRI gives a powerful tool to describe the brain WM structure noninvasively. To potentially enable monitoring of age-related changes and investigation of sex-related brain structure differences on the mapping between the brain connectome and healthy subjects' age and sex, we extract fiber-cluster-based diffusion features and predict sex and age with a novel ensembled neural network classifier. We conduct experiments on the Human Connectome Project (HCP) young adult dataset and show that our model achieves 94.82% accuracy in sex prediction and 2.51 years MAE in age prediction. We also show that the fractional anisotropy (FA) is the most predictive of sex, while the number of fibers is the most predictive of age and the combination of different features can improve the model performance.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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