通过脉动流缓解微流体阵列中的堵塞
Clog mitigation in a microfluidic array via pulsatile flows
摘要：
堵塞是悬浮液运输过程中遇到的常见障碍，并且代表了包括水净化、灌溉、生物制药加工和含水层补给在内的应用中的显著能量和材料成本。与稳定流相比，脉动压力驱动流可以帮助减轻堵塞。在这里，我们实验研究脉动$0.25\,P_0 \leq δP \leq 1.25\,P_0$，其中$P_0$是平均压力的振幅的影响，和脉动$10^{-3}\,{\rm Hz} \leq f \leq 10^{-1}\,{\rm Hz}$的频率对堵塞缓解在使用胶体颗粒的稀悬浮液的平行通道的微流体阵列。阵列几何形状代表经典过滤器，具有随时间推移堵塞的平行孔，产生继续生长并可与其他孔相互作用的滤饼。我们将流速测量与孔隙尺度的直接可视化相结合，以将所观察到的堵塞动态与流速变化相关联。我们观察到，与稳定流动相比，在$0.1$ Hz下的所有脉动振幅产生增加的通量。当经受动态剪切环境时，颗粒的重排可以延迟孔的堵塞或甚至去除现有的堵塞物。然而，这种益处在$10^{-2}$ Hz下急剧降低，并且在$10^{-3}$ Hz下消失，因为与该系统中与堵塞和滤饼生长相关的时间尺度相比，脉动时间尺度变得太大。本研究表明，脉动流是一种很有前途的方法，以延迟堵塞在孔隙和系统规模。
英文摘要：
Clogging is a common obstacle encountered during the transport of suspensions and represents a significant energy and material cost across applications, including water purification, irrigation, biopharmaceutical processing, and aquifer recharge. Pulsatile pressure-driven flows can help mitigate clogging when compared to steady flows. Here, we study experimentally the influence of the amplitude of pulsation $0.25\,P_0 \leq δP \leq 1.25\,P_0$, where $P_0$ is the mean pressure, and of the frequency of pulsation $10^{-3}\,{\rm Hz} \leq f \leq 10^{-1}\,{\rm Hz}$ on clog mitigation in a microfluidic array of parallel channels using a dilute suspension of colloidal particles. The array geometry is representative of a classical filter, with parallel pores that clog over time, yielding a filter cake that continues to grow and can interact with other pores. We combine flow rate measurements with direct visualizations at the pore scale to correlate the observed clogging dynamics with the changes in flow rate. We observe that all pulsatile amplitudes at $0.1$ Hz yield increased throughput compared to steady flows. The rearrangement of particles when subject to a dynamic shear environment can delay the clogging of a pore or even remove an existing clog. However, this benefit is drastically reduced at $10^{-2}$ Hz and disappears at $10^{-3}$ Hz as the pulsatile timescale becomes too large compared to the timescale associated with the clogging and the growth of the filter cakes in this system. The present study demonstrates that pulsatile flows are a promising method to delay clogging at both the pore and system scale.
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