胶体微球流过微加工屏障的快速积聚
Rapid accumulation of colloidal microspheres flowing over microfabricated barriers
摘要：
在不同的系统中，当流过收缩部时颗粒的积聚是普遍存在的现象。一些常见的例子是堵塞的盐结晶附近的盐振荡器的孔，过滤系统堵塞，交通堵塞等的控制研究，积累的事件往往是检查堵塞过程中的微流体通道。迄今为止的实验研究提供了各种物理见解，然而，它们未能解决与人类健康相关的常见累积事件，例如牙齿和动脉斑块。我们通过在微流体环境中使胶体微球流过微结构屏障来模拟动脉斑块样积聚事件。我们的实验揭示了静电力、接触力和流体动力在促进斑块样积聚事件中的作用。相互作用表面之间的德拜长度（静电斥力）减小两个数量级，导致累积量仅略有增加。相比之下，粗糙度增加3倍导致累积量急剧增加。
英文摘要：
Accumulation of particles while flowing past constrictions is a ubiquitous phenomenon observed in diverse systems. Some of the common examples are jamming of salt crystals near the orifice of salt shakers, clogging of filter systems, gridlock in traffics etc. For controlled studies, accumulation events are often examined as clogging process in microfluidic channels. Experimental studies thus far have provided with various physical insights, however, they fail to address commonly encountered accumulation events relevant to human health such as dental and arterial plaques. We simulate arterial plaque like accumulation events by flowing colloidal microspheres over micro-structured barriers in microfluidic environment. Our experiments reveal the role of electrostatic, contact and hydrodynamic forces in facilitating plaque-like build up events. A decrease in Debye length (electrostatic repulsion) between interacting surface by two orders leads to only a minor increase in accumulation. In contrast, an increase in the roughness by 3 times results in dramatic rise of accumulation.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
