COVID-19 Infection Segmentation from Chest CT Images Based on Scale Uncertainty
Nagoya University（名古屋大学）；Nara Institute of Science and Technology（奈良先端科学技术大学院大学）；National Institute of Informatics（国立信息学研究所）；Keio University School of Medicine（庆应义塾大学医学部）；Juntendo University（顺天堂大学）
This paper proposes a segmentation method of infection regions in the lung from CT volumes of COVID-19 patients. COVID-19 spread worldwide, causing many infected patients and deaths. CT image-based diagnosis of COVID-19 can provide quick and accurate diagnosis results. An automated segmentation method of infection regions in the lung provides a quantitative criterion for diagnosis. Previous methods employ whole 2D image or 3D volume-based processes. Infection regions have a considerable variation in their sizes. Such processes easily miss small infection regions. Patch-based process is effective for segmenting small targets. However, selecting the appropriate patch size is difficult in infection region segmentation. We utilize the scale uncertainty among various receptive field sizes of a segmentation FCN to obtain infection regions. The receptive field sizes can be defined as the patch size and the resolution of volumes where patches are clipped from. This paper proposes an infection segmentation network (ISNet) that performs patch-based segmentation and a scale uncertainty-aware prediction aggregation method that refines the segmentation result. We design ISNet to segment infection regions that have various intensity values. ISNet has multiple encoding paths to process patch volumes normalized by multiple intensity ranges. We collect prediction results generated by ISNets having various receptive field sizes. Scale uncertainty among the prediction results is extracted by the prediction aggregation method. We use an aggregation FCN to generate a refined segmentation result considering scale uncertainty among the predictions. In our experiments using 199 chest CT volumes of COVID-19 cases, the prediction aggregation method improved the dice similarity score from 47.6% to 62.1%.
Saratoga High School（萨拉托加高中）；Stanford University（斯坦福大学）
Chest X-rays of coronavirus disease 2019 (COVID-19) patients are frequently obtained to determine the extent of lung disease and are a valuable source of data for creating artificial intelligence models. Most work to date assessing disease severity on chest imaging has focused on segmenting computed tomography (CT) images; however, given that CTs are performed much less frequently than chest X-rays for COVID-19 patients, automated lung lesion segmentation on chest X-rays could be clinically valuable. There currently exists a universal shortage of chest X-rays with ground truth COVID-19 lung le…
The global outbreak of the Coronavirus 2019 (COVID-19) has overloaded worldwide healthcare systems. Computer-aided diagnosis for COVID-19 fast detection and patient triage is becoming critical. This paper proposes a novel self-knowledge distillation based self-supervised learning method for COVID-19 detection from chest X-ray images. Our method can use self-knowledge of images based on similarities of their visual features for self-supervised learning. Experimental results show that our method achieved an HM score of 0.988, an AUC of 0.999, and an accuracy of 0.957 on the largest open COVID-19…
We introduce a new dataset called Synthetic COVID-19 Chest X-ray Dataset for training machine learning models. The dataset consists of 21,295 synthetic COVID-19 chest X-ray images to be used for computer-aided diagnosis. These images, generated via an unsupervised domain adaptation approach, are of high quality. We find that the synthetic images not only improve performance of various deep learning architectures when used as additional training data under heavy imbalance conditions, but also detect the target class with high confidence. We also find that comparable performance can also be achi…
COVID-19 is a global pandemic, and detecting them is a momentous task for medical professionals today due to its rapid mutations. Current methods of examining chest X-rays and CT scan requires profound knowledge and are time consuming, which suggests that it shrinks the precious time of medical practitioners when people's lives are at stake. This study tries to assist this process by achieving state-of-the-art performance in classifying chest X-rays by fine-tuning Vision Transformer(ViT). The proposed approach uses pretrained models, fine-tuned for detecting the presence of COVID-19 disease on…
Concordia Institute for Information Systems Engineering（康考迪亚大学信息系统工程研究所）；Concordia University（康考迪亚大学）
Motivated by the lack of publicly available datasets of chest radiographs of positive patients with Coronavirus disease 2019 (COVID-19), we build the first-of-its-kind open dataset of synthetic COVID-19 chest X-ray images of high fidelity using an unsupervised domain adaptation approach by leveraging class conditioning and adversarial training. Our contributions are twofold. First, we show considerable performance improvements on COVID-19 detection using various deep learning architectures when employing synthetic images as additional training set. Second, we show how our image synthesis metho…
The 2019 novel coronavirus (COVID-19) has spread rapidly all over the world and it is affecting the whole society. The current gold standard test for screening COVID-19 patients is the polymerase chain reaction test. However, the COVID-19 test kits are not widely available and time-consuming. Thus, as an alternative, chest X-rays are being considered for quick screening. Since the presentation of COVID-19 in chest X-rays is varied in features and specialization in reading COVID-19 chest X-rays are required thus limiting its use for diagnosis. To address this challenge of reading chest X-rays b…
University of South Florida（南佛罗里达大学）；University of California, San Francisco（加利福尼亚大学旧金山分校）
Testing for COVID-19 has been unable to keep up with the demand. Further, the false negative rate is projected to be as high as 30% and test results can take some time to obtain. X-ray machines are widely available and provide images for diagnosis quickly. This paper explores how useful chest X-ray images can be in diagnosing COVID-19 disease. We have obtained 122 chest X-rays of COVID-19 and over 4,000 chest X-rays of viral and bacterial pneumonia. A pretrained deep convolutional neural network has been tuned on 102 COVID-19 cases and 102 other pneumonia cases in a 10-fold cross validation. T…
University of Saskatchewan（萨斯喀彻温大学）；International Road Dynamics（国际道路动力学公司）；National Institute of Technology, Trichy（特里奇国家理工学院）
One of the primary clinical observations for screening the infectious by the novel coronavirus is capturing a chest x-ray image. In most of the patients, a chest x-ray contains abnormalities, such as consolidation, which are the results of COVID-19 viral pneumonia. In this study, research is conducted on efficiently detecting imaging features of this type of pneumonia using deep convolutional neural networks in a large dataset. It is demonstrated that simple models, alongside the majority of pretrained networks in the literature, focus on irrelevant features for decision-making. In this paper,…
SARS-CoV-2, also known as COVID-19 or Coronavirus, is a viral contagious disease that is infected by a novel coronavirus, and has been rapidly spreading across the globe. It is very important to test and isolate people to reduce spread, and from here comes the need to do this quickly and efficiently. According to some studies, Chest-CT outperforms RT-PCR lab testing, which is the current standard, when diagnosing COVID-19 patients. Due to this, computer vision researchers have developed various deep learning systems that can predict COVID-19 using a Chest-CT scan correctly to a certain degree.…
IIIT-Delhi（印度德里信息技术学院）；IIT Jodhpur（印度焦特布尔理工学院）；Ashwini Hospital（阿什维尼医院）；Ramakant Heart Care Centre（拉马坎特心脏护理中心）；TeleRadiology Solutions（远程放射学解决方案公司）
With increasing number of COVID-19 cases globally, all the countries are ramping up the testing numbers. While the RT-PCR kits are available in sufficient quantity in several countries, others are facing challenges with limited availability of testing kits and processing centers in remote areas. This has motivated researchers to find alternate methods of testing which are reliable, easily accessible and faster. Chest X-Ray is one of the modalities that is gaining acceptance as a screening modality. Towards this direction, the paper has two primary contributions. Firstly, we present the COVID-1…
Amirkabir University of Technology（阿米尔卡比尔理工大学）；Semnan University（塞姆南大学）
In late 2019 and after COVID-19 pandemic in the world, many researchers and scholars have tried to provide methods for detection of COVID-19 cases. Accordingly, this study focused on identifying COVID-19 cases from chest X-ray images. In this paper, a novel approach to diagnosing coronavirus disease from X-ray images was proposed. In the proposed method, DenseNet169 deep neural network was used to extract the features of X-ray images taken from the patients' chest and the extracted features were then given as input to the Extreme Gradient Boosting (XGBoost) algorithm so that it could perform t…
Early and reliable COVID-19 diagnosis based on chest 3-D CT scans can assist medical specialists in vital circumstances. Deep learning methodologies constitute a main approach for chest CT scan analysis and disease prediction. However, large annotated databases are necessary for developing deep learning models that are able to provide COVID-19 diagnosis across various medical environments in different countries. Due to privacy issues, publicly available COVID-19 CT datasets are highly difficult to obtain, which hinders the research and development of AI-enabled diagnosis methods of COVID-19 ba…
The Coronavirus Disease 2019 (COVID-19) has spread globally and caused serious damage. Chest X-ray images are widely used for COVID-19 diagnosis and the Artificial Intelligence method can increase efficiency and accuracy. In the Challenge of Chest XR COVID-19 detection in Ethics and Explainability for Responsible Data Science (EE-RDS) conference 2021, we proposed a method that combined Swin Transformer and Transformer in Transformer to classify chest X-ray images as three classes: COVID-19, Pneumonia, and Normal (healthy) and achieved 0.9475 accuracies on the test set.
Technical University of Munich（慕尼黑工业大学）；Stanford University（斯坦福大学）
Interpreting chest radiograph, a.ka. chest x-ray, images is a necessary and crucial diagnostic tool used by medical professionals to detect and identify many diseases that may plague a patient. Although the images themselves contain a wealth of valuable information, their usefulness may be limited by how well they are interpreted, especially when the reviewing radiologist may be fatigued or when or an experienced radiologist is unavailable. Research in the use of deep learning models to analyze chest radiographs yielded impressive results where, in some instances, the models outperformed pract…
A newly identified coronavirus disease called COVID-19 mainly affects the human respiratory system. COVID-19 is an infectious disease caused by a virus originating in Wuhan, China, in December 2019. Early diagnosis is the primary challenge of health care providers. In the earlier stage, medical organizations were dazzled because there were no proper health aids or medicine to detect a COVID-19. A new diagnostic tool RT-PCR (Reverse Transcription Polymerase Chain Reaction), was introduced. It collects swab specimens from the patient's nose or throat, where the COVID-19 virus gathers. This metho…
Mohamed bin Zayed University of Artificial Intelligence（穆罕默德·本·扎耶德人工智能大学）
Quick and accurate diagnosis is of paramount importance to mitigate the effects of COVID-19 infection, particularly for severe cases. Enormous effort has been put towards developing deep learning methods to classify and detect COVID-19 infections from chest radiography images. However, recently some questions have been raised surrounding the clinical viability and effectiveness of such methods. In this work, we investigate the impact of multi-task learning (classification and segmentation) on the ability of CNNs to differentiate between various appearances of COVID-19 infections in the lung. W…
In 2019, the entire world is facing a situation of health emergency due to a newly emerged coronavirus (COVID-19). Almost 196 countries are affected by covid-19, while USA, Italy, China, Spain, Iran, and France have the maximum active cases of COVID-19. The issues, medical and healthcare departments are facing in delay of detecting the COVID-19. Several artificial intelligence based system are designed for the automatic detection of COVID-19 using chest x-rays. In this article we will discuss the different approaches used for the detection of COVID-19 and the challenges we are facing. It is ma…
There are multiple papers published about different AI models for the COVID-19 diagnosis with promising results. Unfortunately according to the reviews many of the papers do not reach the level of sophistication needed for a clinically usable model. In this paper I go through multiple review papers, guidelines, and other relevant material in order to generate more comprehensive requirements for the future papers proposing a AI based diagnosis of the COVID-19 from chest X-ray data (CXR). Main findings are that a clinically usable AI needs to have an extremely good documentation, comprehensive s…
One of the critical tools for early detection and subsequent evaluation of the incidence of lung diseases is chest radiography. This study presents a real-world implementation of a convolutional neural network (CNN) based Carebot Covid app to detect COVID-19 from chest X-ray (CXR) images. Our proposed model takes the form of a simple and intuitive application. Used CNN can be deployed as a STOW-RS prediction endpoint for direct implementation into DICOM viewers. The results of this study show that the deep learning model based on DenseNet and ResNet architecture can detect SARS-CoV-2 from CXR …
Indian Institute of Technology Delhi（德里印度理工学院）；University of Bath（巴斯大学）；Indian Institute of Technology Kanpur（坎普尔印度理工学院）；All India Institute of Medical Sciences Delhi（德里全印度医学科学研究所）
The exponential increase in COVID-19 patients is overwhelming healthcare systems across the world. With limited testing kits, it is impossible for every patient with respiratory illness to be tested using conventional techniques (RT-PCR). The tests also have long turn-around time, and limited sensitivity. Detecting possible COVID-19 infections on Chest X-Ray may help quarantine high risk patients while test results are awaited. X-Ray machines are already available in most healthcare systems, and with most modern X-Ray systems already digitized, there is no transportation time involved for the …
Carnegie Mellon University（卡内基梅隆大学）；University of Illinois at Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）；Petuum Inc.（Petuum 公司）
Due to the shortage of COVID-19 viral testing kits and the long waiting time, radiology imaging is used to complement the screening process and triage patients into different risk levels. Deep learning based methods have taken an active role in automatically detecting COVID-19 disease in chest x-ray images, as witnessed in many recent works in early 2020. Most of these works first train a Convolutional Neural Network (CNN) on an existing large-scale chest x-ray image dataset and then fine-tune it with a COVID-19 dataset at a much smaller scale. However, direct transfer across datasets from dif…
Sierra Research S.L（塞拉研究有限公司）；Universidad de Alicante（阿利坎特大学）；Medbravo（Medbravo医疗公司）；Fundación para el Fomento de la Investigación Sanitario y Biomédica de la Comunidad Valenciana（瓦伦西亚自治区卫生与生物医学研究促进基金会）；Hospital San Juan de Alicante（阿利坎特圣胡安医院）；Universidad Miguel Hernández（米格尔·埃尔南德斯大学）
In this work we present a method for the detection of radiological findings, their location and differential diagnoses from chest x-rays. Unlike prior works that focus on the detection of few pathologies, we use a hierarchical taxonomy mapped to the Unified Medical Language System (UMLS) terminology to identify 189 radiological findings, 22 differential diagnosis and 122 anatomic locations, including ground glass opacities, infiltrates, consolidations and other radiological findings compatible with COVID-19. We train the system on one large database of 92,594 frontal chest x-rays (AP or PA, st…
Indian Institute of Information Technology, Sri City, Chittoor（印度信息技术学院，斯里城，奇图尔）；Indian Institute of Information Technology, Allahabad（印度信息技术学院，阿拉哈巴德）
Covid-19 global pandemic continues to devastate health care systems across the world. At present, the Covid-19 testing is costly and time-consuming. Chest X-Ray (CXR) testing can be a fast, scalable, and non-invasive method. The existing methods suffer due to the limited CXR samples available from Covid-19. Thus, inspired by the limitations of the open-source work in this field, we propose attention guided contrastive CNN architecture (AC-CovidNet) for Covid-19 detection in CXR images. The proposed method learns the robust and discriminative features with the help of contrastive loss. Moreover…
Warsaw University of Technology（华沙理工大学）；Sano Centre for Computational Medicine（萨诺计算医学中心）；Jagiellonian University（雅盖隆大学）；Tooploox
A critical step in the fight against COVID-19, which continues to have a catastrophic impact on peoples lives, is the effective screening of patients presented in the clinics with severe COVID-19 symptoms. Chest radiography is one of the promising screening approaches. Many studies reported detecting COVID-19 in chest X-rays accurately using deep learning. A serious limitation of many published approaches is insufficient attention paid to explaining decisions made by deep learning models. Using explainable artificial intelligence methods, we demonstrate that model decisions may rely on confoun…
University of Chittagong（吉大港大学）；Charles Sturt University（查尔斯特大学）
The COVID-19 pandemic continues to severely undermine the prosperity of the global health system. To combat this pandemic, effective screening techniques for infected patients are indispensable. There is no doubt that the use of chest X-ray images for radiological assessment is one of the essential screening techniques. Some of the early studies revealed that the patient's chest X-ray images showed abnormalities, which is natural for patients infected with COVID-19. In this paper, we proposed a parallel-dilated convolutional neural network (CNN) based COVID-19 detection system from chest x-ray…
Spreading of COVID-19 virus has increased the efforts to provide testing kits. Not only the preparation of these kits had been hard, rare, and expensive but also using them is another issue. Results have shown that these kits take some crucial time to recognize the virus, in addition to the fact that they encounter with 30% loss. In this paper, we have studied the usage of x-ray pictures which are ubiquitous, for the classification of COVID-19 chest Xray images, by the existing convolutional neural networks (CNNs). We intend to train chest x-rays of infected and not infected ones with differen…
The current COVID-19 pandemic is a serious threat to humanity that directly affects the lungs. Automatic identification of COVID-19 is a challenge for health care officials. The standard gold method for diagnosing COVID-19 is Reverse Transcription Polymerase Chain Reaction (RT-PCR) to collect swabs from affected people. Some limitations encountered while collecting swabs are related to accuracy and longtime duration. Chest CT (Computed Tomography) is another test method that helps healthcare providers quickly identify the infected lung areas. It was used as a supporting tool for identifying CO…
University of Leeds（利兹大学）；Leeds Teaching Hospitals NHS Trust（利兹教学医院 NHS 信托基金）
Since the emergence of COVID-19, deep learning models have been developed to identify COVID-19 from chest X-rays. With little to no direct access to hospital data, the AI community relies heavily on public data comprising numerous data sources. Model performance results have been exceptional when training and testing on open-source data, surpassing the reported capabilities of AI in pneumonia-detection prior to the COVID-19 outbreak. In this study impactful models are trained on a widely used open-source data and tested on an external test set and a hospital dataset, for the task of classifyin…
Beijing University of Posts and Telecommunications（北京邮电大学）
The COVID-19 epidemic has become a major safety and health threat worldwide. Imaging diagnosis is one of the most effective ways to screen COVID-19. This project utilizes several open-source or public datasets to present an open-source dataset of COVID-19 CXRs, named COVID-19-CXR-Dataset, and introduces a deep convolutional neural network model. The model validates on 740 test images and achieves 87.3% accuracy, 89.67 % precision, and 84.46% recall, and correctly classifies 98 out of 100 COVID-19 x-ray images in test set with more than 81% prediction probability under the condition of 95% conf…
Amirkabir University of Technology（阿米尔卡比尔理工大学）；Semnan University（塞姆南大学）
The new coronavirus (known as COVID-19) was first identified in Wuhan and quickly spread worldwide, wreaking havoc on the economy and people's everyday lives. Fever, cough, sore throat, headache, exhaustion, muscular aches, and difficulty breathing are all typical symptoms of COVID-19. A reliable detection technique is needed to identify affected individuals and care for them in the early stages of COVID-19 and reduce the virus's transmission. The most accessible method for COVID-19 identification is RT-PCR; however, due to its time commitment and false-negative results, alternative options mu…
Shandong University of Traditional Chinese Medicine（山东中医药大学）；Qingdao Academy of Chinese Medical Sciences（青岛中医科学院）；Shandong University（山东大学）；Shandong Normal University（山东师范大学）；Affiliated Hospital of Shandong University of Traditional Chinese Medicine（山东中医药大学附属医院）
This paper addresses the new problem of automated screening of coronavirus disease 2019 (COVID-19) based on chest X-rays, which is urgently demanded toward fast stopping the pandemic. However, robust and accurate screening of COVID-19 from chest X-rays is still a globally recognized challenge because of two bottlenecks: 1) imaging features of COVID-19 share some similarities with other pneumonia on chest X-rays, and 2) the misdiagnosis rate of COVID-19 is very high, and the misdiagnosis cost is expensive. While a few pioneering works have made much progress, they underestimate both crucial bot…
Universidad Autónoma de Manizales（马尼萨莱斯自治大学）；Universidad Nacional de Colombia（哥伦比亚国立大学）
There is a necessity to develop affordable, and reliable diagnostic tools, which allow containing the COVID-19 spreading. Machine Learning (ML) algorithms have been proposed to design support decision-making systems to assess chest X-ray images, which have proven to be useful to detect and evaluate disease progression. Many research articles are published around this subject, which makes it difficult to identify the best approaches for future work. This paper presents a systematic review of ML applied to COVID-19 detection using chest X-ray images, aiming to offer a baseline for researchers in…
West Bengal State University（西孟加拉邦立大学）；Indian Statistical Institute（印度统计研究所）；Jamia Hamdard (Deemed University)（贾米亚哈姆达德大学）
With the ever increasing demand for screening millions of prospective "novel coronavirus" or COVID-19 cases, and due to the emergence of high false negatives in the commonly used PCR tests, the necessity for probing an alternative simple screening mechanism of COVID-19 using radiological images (like chest X-Rays) assumes importance. In this scenario, machine learning (ML) and deep learning (DL) offer fast, automated, effective strategies to detect abnormalities and extract key features of the altered lung parenchyma, which may be related to specific signatures of the COVID-19 virus. However, …
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；Hainan University（海南大学）；University of Macau（澳门大学）
AI plays an important role in COVID-19 identification. Computer vision and deep learning techniques can assist in determining COVID-19 infection with Chest X-ray Images. However, for the protection and respect of the privacy of patients, the hospital's specific medical-related data did not allow leakage and sharing without permission. Collecting such training data was a major challenge. To a certain extent, this has caused a lack of sufficient data samples when performing deep learning approaches to detect COVID-19. Federated Learning is an available way to address this issue. It can effective…
In a worldwide health crisis as exigent as COVID-19, there has become a pressing need for rapid, reliable diagnostics. Currently, popular testing methods such as reverse transcription polymerase chain reaction (RT-PCR) can have high false negative rates. Consequently, COVID-19 patients are not accurately identified nor treated quickly enough to prevent transmission of the virus. However, the recent rise of medical CT data has presented promising avenues, since CT manifestations contain key characteristics indicative of COVID-19. This study aimed to take a novel approach in the machine learning…
Coronavirus disease (COVID-19) is a contagious infection caused by severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) and it has infected and killed millions of people across the globe. In the absence of specific drugs or vaccines for the treatment of COVID-19 and the limitation of prevailing diagnostic techniques, there is a requirement for some alternate automatic screening systems that can be used by the physicians to quickly identify and isolate the infected patients. A chest X-ray (CXR) image can be used as an alternative modality to detect and diagnose the COVID-19. In this stu…
Indian Institute of Technology, Jammu（印度理工学院贾姆姆分校）；University of Pennsylvania（宾夕法尼亚大学）
We propose a two-stage Convolutional Neural Network (CNN) based classification framework for detecting COVID-19 and Community-Acquired Pneumonia (CAP) using the chest Computed Tomography (CT) scan images. In the first stage, an infection - COVID-19 or CAP, is detected using a pre-trained DenseNet architecture. Then, in the second stage, a fine-grained three-way classification is done using EfficientNet architecture. The proposed COVID+CAP-CNN framework achieved a slice-level classification accuracy of over 94% at identifying COVID-19 and CAP. Further, the proposed framework has the potential t…
During the COVID-19 pandemic, there has been an emerging need for rapid, dedicated, and point-of-care COVID-19 patient disposition techniques to optimize resource utilization and clinical workflow. In view of this need, we present COVID-MobileXpert: a lightweight deep neural network (DNN) based mobile app that can use chest X-ray (CXR) for COVID-19 case screening and radiological trajectory prediction. We design and implement a novel three-player knowledge transfer and distillation (KTD) framework including a pre-trained attending physician (AP) network that extracts CXR imaging features from …
National Institute of Technology, Hamirpur（国家理工学院哈米尔布尔分校）；Emory University School of Medicine（埃默里大学医学院）
The COVID-19 (coronavirus disease 2019) pandemic affected more than 186 million people with over 4 million deaths worldwide by June 2021. The magnitude of which has strained global healthcare systems. Chest Computed Tomography (CT) scans have a potential role in the diagnosis and prognostication of COVID-19. Designing a diagnostic system which is cost-efficient and convenient to operate on resource-constrained devices like mobile phones would enhance the clinical usage of chest CT scans and provide swift, mobile, and accessible diagnostic capabilities. This work proposes developing a novel And…
University of Waterloo（滑铁卢大学）；Waterloo Artificial Intelligence Institute（滑铁卢人工智能研究所）；DarwinAI Corp.（达尔文人工智能公司）
The COVID-19 pandemic continues to have a devastating effect on the health and well-being of the global population. A critical step in the fight against COVID-19 is effective screening of infected patients, with one of the key screening approaches being radiology examination using chest radiography. Motivated by this and inspired by the open source efforts of the research community, in this study we introduce COVID-Net, a deep convolutional neural network design tailored for the detection of COVID-19 cases from chest X-ray (CXR) images that is open source and available to the general public. T…
Université de Haute-Alsace（上阿尔萨斯大学）；Université de Strasbourg（斯特拉斯堡大学）；University of Lille（里尔大学）；YNCREA-ISEN Lille（里尔YNCREA-ISEN工程学院）；University of the Basque Country（巴斯克大学）；IKERBASQUE, Basque Foundation for Science（伊克尔巴斯克巴斯克科学基金会）；The University of Tokyo（东京大学）；CNRS（法国国家科学研究中心）；Inserm（法国国家健康与医学研究院）；CHU Lille（里尔大学医院）
Coronavirus disease 2019 (COVID-19) is an infectious disease with first symptoms similar to the flu. COVID-19 appeared first in China and very quickly spreads to the rest of the world, causing then the 2019-20 coronavirus pandemic. In many cases, this disease causes pneumonia. Since pulmonary infections can be observed through radiography images, this paper investigates deep learning methods for automatically analyzing query chest X-ray images with the hope to bring precision tools to health professionals towards screening the COVID-19 and diagnosing confirmed patients. In this context, traini…
University of Turin（都灵大学）；Azienda Ospedaliera Città della Salute e della Scienza（健康与科学城医院）
The possibility to use widespread and simple chest X-ray (CXR) imaging for early screening of COVID-19 patients is attracting much interest from both the clinical and the AI community. In this study we provide insights and also raise warnings on what is reasonable to expect by applying deep-learning to COVID classification of CXR images. We provide a methodological guide and critical reading of an extensive set of statistical results that can be obtained using currently available datasets. In particular, we take the challenge posed by current small size COVID data and show how significant can …
One of the most contentious areas of research in Medical Image Preprocessing is 3D CT-scan. With the rapid spread of COVID-19, the function of CT-scan in properly and swiftly diagnosing the disease has become critical. It has a positive impact on infection prevention. There are many tasks to diagnose the illness through CT-scan images, include COVID-19. In this paper, we propose a method that using a Stacking Deep Neural Network to detect the Covid 19 through the series of 3D CT-scans images . In our method, we experiment with two backbones are DenseNet 121 and ResNet 101. This method achieves…
Because the infection by Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19) causes the pneumonia-like effect in the lungs, the examination of chest x-rays can help to diagnose the diseases. For automatic analysis of images, they are represented in machines by a set of semantic features. Deep Learning (DL) models are widely used to extract features from images. General deep features may not be appropriate to represent chest x-rays as they have a few semantic regions. Though the Bag of Visual Words (BoVW) based features are shown to be more appropriate for x-ray type of images, existing …
Christian Brothers University（基督教兄弟大学）；University of Dayton（代顿大学）
With a Coronavirus disease (COVID-19) case count exceeding 10 million worldwide, there is an increased need for a diagnostic capability. The main variables in increasing diagnostic capability are reduced cost, turnaround or diagnosis time, and upfront equipment cost and accessibility. Two candidates for machine learning COVID-19 diagnosis are Computed Tomography (CT) scans and plain chest X-rays. While CT scans score higher in sensitivity, they have a higher cost, maintenance requirement, and turnaround time as compared to plain chest X-rays. The use of portable chest X-radiograph (CXR) is rec…
Clínica Universidad de Navarra（纳瓦拉大学诊所）；Health Time；Hôpital Foch（福煦医院）；Houston Methodist（休斯顿卫理公会医院）；Donald and Barbara Zucker School of Medicine, Feinstein Institutes for Medical Research, Northwell Health（诺斯韦尔健康唐纳德和芭芭拉·祖克医学院，费因斯坦医学研究所）；Penn Medicine（宾夕法尼亚医学院）；Siemens Healthineers（西门子医疗）；University Hospital Basel（巴塞尔大学医院）；Vancouver General Hospital（温哥华总医院）
Objectives: To investigate machine-learning classifiers and interpretable models using chest CT for detection of COVID-19 and differentiation from other pneumonias, ILD and normal CTs. Methods: Our retrospective multi-institutional study obtained 2096 chest CTs from 16 institutions (including 1077 COVID-19 patients). Training/testing cohorts included 927/100 COVID-19, 388/33 ILD, 189/33 other pneumonias, and 559/34 normal (no pathologies) CTs. A metric-based approach for classification of COVID-19 used interpretable features, relying on logistic regression and random forests. A deep learning-b…
Hong Kong Baptist University（香港浸会大学）；Hong Kong University of Science and Technology（香港科技大学）；Hangzhou Dianzi University（杭州电子科技大学）；Tsinghua University（清华大学）
The COVID-19 pandemic has spread globally for several months. Because its transmissibility and high pathogenicity seriously threaten people's lives, it is crucial to accurately and quickly detect COVID-19 infection. Many recent studies have shown that deep learning (DL) based solutions can help detect COVID-19 based on chest CT scans. However, most existing work focuses on 2D datasets, which may result in low quality models as the real CT scans are 3D images. Besides, the reported results span a broad spectrum on different datasets with a relatively unfair comparison. In this paper, we first u…
Isfahan University of Technology（伊斯法罕理工大学）；Snap Inc.（Snap公司）；Isfahan University of Medical Sciences（伊斯法罕医科大学）；The University of Iowa（爱荷华大学）
The novel corona-virus disease (COVID-19) pandemic has caused a major outbreak in more than 200 countries around the world, leading to a severe impact on the health and life of many people globally. As of Aug 25th of 2020, more than 20 million people are infected, and more than 800,000 death are reported. Computed Tomography (CT) images can be used as a as an alternative to the time-consuming "reverse transcription polymerase chain reaction (RT-PCR)" test, to detect COVID-19. In this work we developed a deep learning framework to predict COVID-19 from CT images. We propose to use an attentiona…
Nagoya University（名古屋大学）；Nara Institute of Science and Technology（奈良先端科学技术大学院大学）；National Institute of Informatics（国立信息学研究所）；Keio University School of Medicine（庆应义塾大学医学部）；Juntendo University（顺天堂大学）
This paper proposes an automated segmentation method of infection and normal regions in the lung from CT volumes of COVID-19 patients. From December 2019, novel coronavirus disease 2019 (COVID-19) spreads over the world and giving significant impacts to our economic activities and daily lives. To diagnose the large number of infected patients, diagnosis assistance by computers is needed. Chest CT is effective for diagnosis of viral pneumonia including COVID-19. A quantitative analysis method of condition of the lung from CT volumes by computers is required for diagnosis assistance of COVID-19.…
Birla Institute of Technology and Science, Pilani, Dubai Campus（比尔拉技术与科学学院皮拉尼分校迪拜校区）
The COVID-19 (coronavirus) is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus was first identified in mid-December 2019 in the Hubei province of Wuhan, China and by now has spread throughout the planet with more than 75.5 million confirmed cases and more than 1.67 million deaths. With limited number of COVID-19 test kits available in medical facilities, it is important to develop and implement an automatic detection system as an alternative diagnosis option for COVID-19 detection that can used on a commercial scale. Chest X-ray is the first…
University of Chittagong（吉大港大学）；Charles Sturt University（查尔斯特大学）
This paper proposed an ensemble of deep convolutional neural networks (CNN) based on EfficientNet, named ECOVNet, to detect COVID-19 using a large chest X-ray data set. At first, the open-access large chest X-ray collection is augmented, and then ImageNet pre-trained weights for EfficientNet is transferred with some customized fine-tuning top layers that are trained, followed by an ensemble of model snapshots to classify chest X-rays corresponding to COVID-19, normal, and pneumonia. The predictions of the model snapshots, which are created during a single training, are combined through two ens…
University of Waterloo（滑铁卢大学）；Niagara Health（尼亚加拉医疗）；McMaster University（麦克马斯特大学）；Hamilton Health Sciences（汉密尔顿健康科学中心）；Waterloo Artificial Intelligence Institute（滑铁卢人工智能研究院）；DarwinAI Corp.（达尔文人工智能公司）
The COVID-19 pandemic continues to rage on, with multiple waves causing substantial harm to health and economies around the world. Motivated by the use of CT imaging at clinical institutes around the world as an effective complementary screening method to RT-PCR testing, we introduced COVID-Net CT, a neural network tailored for detection of COVID-19 cases from chest CT images as part of the open source COVID-Net initiative. However, one potential limiting factor is restricted quantity and diversity given the single nation patient cohort used. In this study, we introduce COVID-Net CT-2, enhance…
Reliable COVID-19 Detection Using Chest X-ray Images
Faculty of Information Technology and Communication Sciences, Tampere University（坦佩雷大学信息技术与通信科学学院）；Department of Electrical Engineering, Qatar University（卡塔尔大学电气工程学院）
Intelligent Medical Image Computing Systems (IMICS) Lab（智能医学影像计算系统实验室）；The Hospital for Sick Children（病童医院）；University of Toronto（多伦多大学）
COVID-19 spread across the globe at an immense rate has left healthcare systems incapacitated to diagnose and test patients at the needed rate. Studies have shown promising results for detection of COVID-19 from viral bacterial pneumonia in chest X-rays. Automation of COVID-19 testing using medical images can speed up the testing process of patients where health care systems lack sufficient numbers of the reverse-transcription polymerase chain reaction (RT-PCR) tests. Supervised deep learning models such as convolutional neural networks (CNN) need enough labeled data for all classes to correct…
Beijing Jingzhen Medical Technology Ltd.（北京精诊医疗科技有限公司）；Tsinghua University（清华大学）；Australian Institute for Machine Learning, The University of Adelaide（阿德莱德大学澳大利亚机器学习研究所）；Xidian University（西安电子科技大学）
A novel coronavirus disease 2019 (COVID-19) was detected and has spread rapidly across various countries around the world since the end of the year 2019, Computed Tomography (CT) images have been used as a crucial alternative to the time-consuming RT-PCR test. However, pure manual segmentation of CT images faces a serious challenge with the increase of suspected cases, resulting in urgent requirements for accurate and automatic segmentation of COVID-19 infections. Unfortunately, since the imaging characteristics of the COVID-19 infection are diverse and similar to the backgrounds, existing med…
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). Imaging tests such as chest X-ray (CXR) and computed tomography (CT) can provide useful information to clinical staff for facilitating a diagnosis of COVID-19 in a more efficient and comprehensive manner. As a breakthrough of artificial intelligence (AI), deep learning has been applied to perform COVID-19 infection region segmentation and disease classification by analyzing CXR and CT data. However, prediction uncertainty of deep learning models for these tasks, which is very important to s…
University of New South Wales（新南威尔士大学）；Inception Institute of Artificial Intelligence（Inception人工智能研究院）；Stanford University（斯坦福大学）
The current pandemic, caused by the outbreak of a novel coronavirus (COVID-19) in December 2019, has led to a global emergency that has significantly impacted economies, healthcare systems and personal wellbeing all around the world. Controlling the rapidly evolving disease requires highly sensitive and specific diagnostics. While real-time RT-PCR is the most commonly used, these can take up to 8 hours, and require significant effort from healthcare professionals. As such, there is a critical need for a quick and automatic diagnostic system. Diagnosis from chest CT images is a promising direct…
University of Dhaka（达卡大学）；Qatar University（卡塔尔大学）；Qatar Foundation（卡塔尔基金会）；Universiti Kebangsaan Malaysia（马来西亚国民大学）；College of Medicine（医学院）；University of Engineering and Technology, Peshawar（白沙瓦工程技术大学）
The use of computer-aided diagnosis in the reliable and fast detection of coronavirus disease (COVID-19) has become a necessity to prevent the spread of the virus during the pandemic to ease the burden on the medical infrastructure. Chest X-ray (CXR) imaging has several advantages over other imaging techniques as it is cheap, easily accessible, fast and portable. This paper explores the effect of various popular image enhancement techniques and states the effect of each of them on the detection performance. We have compiled the largest X-ray dataset called COVQU-20, consisting of 18,479 normal…
