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arXiv 2112.04047cond-mat.softcond-mat.mtrl-sciphysics.bio-ph
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二维顶点模型的流变学

Rheology of 2D vertex model

Doron Grossman, Jean-Francois Joanny

AI总结:

该研究采用解析粗粒化连续介质公式,理论探究二维上皮组织顶点模型的流变特性,揭示其剪切变稀等流变规律及振荡基底支撑下的取向变化与三临界点特征。

摘要:

组织的力学特性对细胞分裂、分化或形态发生等所有组织特性发挥着至关重要。本文采用解析粗粒化连续介质公式,从理论上研究了由离散类顶点模型描述的二维上皮组织的流变学特性。研究表明,上皮组织在恒定剪切速率下大多表现为剪切稀化,且在特定条件下会从低剪切速率下的剪切增稠转变为高剪切速率下的剪切稀化。本文给出了线性区域内振荡应变实验中组织响应的解析表达式,并通过数值计算得到了非线性区域的响应。当组织由振荡基底支撑时,其取向会随频率和基底泊松比发生变化。取向变化可能是渐进的,也可能是突变的,这取决于组织和基底参数,且构型相空间存在一个三临界点。

英文摘要:

The mechanical properties of tissues play an essential role for all tissue properties such as cell division, and differentiation or morphogenesis. Here, we study theoretically the rheology of 2-dimensional epithelial tissues described by a discrete vertex-like model, using an analytical coarsegrained continuum formulation. We show that epithelial tissues are most often shear-thinning under constant shear rate, and in certain circumstances cross over from shear thickening at low shear rates to shear thinning at high shear rates. We give an analytical expression of the tissue response in an oscillating strain experiment in the linear regime, and calculate it numerically in the non-linear regime. When the tissue is supported by an oscillating substrate, it reorients depending on frequency and substrate's Poisson's ratio. Reorientation could be gradual or abrupt, depending on tissue and substrate parameters, and the configuration phase space exhibits a tricritical point.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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