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arXiv 2107.06503stat.ME
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半监督双组分混合模型的矩置信区间方法

Method of Moments Confidence Intervals for a Semi-Supervised Two-Component Mixture Model

Bradley Lubich, Daniel Jeske, Weixin Yao

摘要:

来自未治疗患者的反应分布和该分布的偏移的混合物是来自一组治疗患者的反应的有用模型。混合模型解释了这样一个事实,即并非治疗组中的所有患者都会对治疗产生应答,因此其应答遵循与未治疗患者的应答相同的分布。在这种情况下,处理效应包括作为应答者的治疗患者的分数和应答者分布的变化幅度。在本文中,我们调查的处理效应的矩估计方法的性质,并证明其有用性获得近似置信区间,而无需任何参数假设的响应分布。

英文摘要:

A mixture of a distribution of responses from untreated patients and a shift of that distribution is a useful model for the responses from a group of treated patients. The mixture model accounts for the fact that not all the patients in the treated group will respond to the treatment and consequently their responses follow the same distribution as the responses from untreated patients. The treatment effect in this context consists of both the fraction of the treated patients that are responders and the magnitude of the shift in the distribution for the responders. In this paper, we investigate properties of the method of moment estimators for the treatment effect and demonstrate their usefulness for obtaining approximate confidence intervals without any parametric assumptions about the distribution of responses.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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