Sparse regression is frequently employed in diverse scientific settings as a feature selection method. A pervasive aspect of scientific data that hampers both feature selection and estimation is the presence of strong correlations between predictive features. These fundamental issues are often not appreciated by practitioners, and jeapordize conclusions drawn from estimated models. On the other hand, theoretical results on sparsity-inducing regularized regression such as the Lasso have largely addressed conditions for selection consistency via asymptotics, and disregard the problem of model selection, whereby regularization parameters are chosen. In this numerical study, we address these issues through exhaustive characterization of the performance of several regression estimators, coupled with a range of model selection strategies. These estimators and selection criteria were examined across correlated regression problems with varying degrees of signal to noise, distribution of the non-zero model coefficients, and model sparsity. Our results reveal a fundamental tradeoff between false positive and false negative control in all regression estimators and model selection criteria examined. Additionally, we are able to numerically explore a transition point modulated by the signal-to-noise ratio and spectral properties of the design covariance matrix at which the selection accuracy of all considered algorithms degrades. Overall, we find that SCAD coupled with BIC or empirical Bayes model selection performs the best feature selection across the regression problems considered.
Leading methods for support recovery in high-dimensional regression, such as Lasso, have been well-studied and their limitations in the context of correlated design have been characterized with precise incoherence conditions. In this work, we present a similar treatment of selection consistency for marginal regression (MR), a computationally efficient family of methods with connections to decision trees. Selection based on marginal regression is also referred to as covariate screening or independence screening and is a popular approach in applied work, especially in ultra high-dimensional sett…
Functional neuroimaging can measure the brain?s response to an external stimulus. It is used to perform brain mapping: identifying from these observations the brain regions involved. This problem can be cast into a linear supervised learning task where the neuroimaging data are used as predictors for the stimulus. Brain mapping is then seen as a support recovery problem. On functional MRI (fMRI) data, this problem is particularly challenging as i) the number of samples is small due to limited acquisition time and ii) the variables are strongly correlated. We propose to overcome these difficult…
Heavy-tailed continuous shrinkage priors, such as the horseshoe prior, are widely used for sparse estimation problems. However, there is limited work extending these priors to predictors with grouping structures. Of particular interest in this article, is regression coefficient estimation where pockets of high collinearity in the covariate space are contained within known covariate groupings. To assuage variance inflation due to multicollinearity we propose the group inverse-gamma gamma (GIGG) prior, a heavy-tailed prior that can trade-off between local and group shrinkage in a data adaptive f…
Sparse recovery and subset selection are fundamental problems in varied communities, including signal processing, statistics and machine learning. Herein, we focus on an important greedy algorithm for these problems: Backward Stepwise Regression. We present novel guarantees for the algorithm, propose an efficient, numerically stable implementation, and put forth Stepwise Regression with Replacement (SRR), a new family of two-stage algorithms that employs both forward and backward steps for compressed sensing problems. Prior work on the backward algorithm has proven its optimality for the subse…
Lasso is a popular and efficient approach to simultaneous estimation and variable selection in high-dimensional regression models. In this paper, a robust LAD-lasso method for multiple outcomes is presented that addresses the challenges of non-normal outcome distributions and outlying observations. Measured covariate data from space or time, or spectral bands or genomic positions often have natural correlation structure arising from measuring distance between the covariates. The proposed multi-outcome approach includes handling of such covariate blocks by a group fusion penalty, which encourag…
In this paper, we investigate a multivariate multi-response (MVMR) linear regression problem, which contains multiple linear regression models with differently distributed design matrices, and different regression and output vectors. The goal is to recover the support union of all regression vectors using $l_1/l_2$-regularized Lasso. We characterize sufficient and necessary conditions on sample complexity \emph{as a sharp threshold} to guarantee successful recovery of the support union. Namely, if the sample size is above the threshold, then $l_1/l_2$-regularized Lasso correctly recovers the s…
We demonstrate that the primal-dual witness proof method may be used to establish variable selection consistency and $\ell_\infty$-bounds for sparse regression problems, even when the loss function and/or regularizer are nonconvex. Using this method, we derive two theorems concerning support recovery and $\ell_\infty$-guarantees for the regression estimator in a general setting. Our results provide rigorous theoretical justification for the use of nonconvex regularization: For certain nonconvex regularizers with vanishing derivative away from the origin, support recovery consistency may be gua…
In multivariate regression, a $K$-dimensional response vector is regressed upon a common set of $p$ covariates, with a matrix $B^*\in\mathbb{R}^{p\times K}$ of regression coefficients. We study the behavior of the multivariate group Lasso, in which block regularization based on the $\ell_1/\ell_2$ norm is used for support union recovery, or recovery of the set of $s$ rows for which $B^*$ is nonzero. Under high-dimensional scaling, we show that the multivariate group Lasso exhibits a threshold for the recovery of the exact row pattern with high probability over the random design and noise that …
We consider the high-dimensional sparse linear regression problem of accurately estimating a sparse vector using a small number of linear measurements that are contaminated by noise. It is well known that the standard cadre of computationally tractable sparse regression algorithms---such as the Lasso, Orthogonal Matching Pursuit (OMP), and their extensions---perform poorly when the measurement matrix contains highly correlated columns. To address this shortcoming, we develop a simple greedy algorithm, called SWAP, that iteratively swaps variables until convergence. SWAP is surprisingly effecti…
We consider estimation in a high-dimensional linear model with strongly correlated variables. We propose to cluster the variables first and do subsequent sparse estimation such as the Lasso for cluster-representatives or the group Lasso based on the structure from the clusters. Regarding the first step, we present a novel and bottom-up agglomerative clustering algorithm based on canonical correlations, and we show that it finds an optimal solution and is statistically consistent. We also present some theoretical arguments that canonical correlation based clustering leads to a better-posed comp…
Identifying homogeneous subgroups of variables can be challenging in high dimensional data analysis with highly correlated predictors. We propose a new method called Hexagonal Operator for Regression with Shrinkage and Equality Selection, HORSES for short, that simultaneously selects positively correlated variables and identifies them as predictive clusters. This is achieved via a constrained least-squares problem with regularization that consists of a linear combination of an L_1 penalty for the coefficients and another L_1 penalty for pairwise differences of the coefficients. This specificat…
The linear model, in which a set of observations is assumed to be given by a linear combination of columns of a matrix, has long been the mainstay of the statistics and signal processing literature. One particular challenge for inference under linear models is understanding the conditions on the dictionary under which reliable inference is possible. This challenge has attracted renewed attention in recent years since many modern inference problems deal with the "underdetermined" setting, in which the number of observations is much smaller than the number of columns in the dictionary. This pape…
This paper introduces a simple principle for robust high-dimensional statistical inference via an appropriate shrinkage on the data. This widens the scope of high-dimensional techniques, reducing the moment conditions from sub-exponential or sub-Gaussian distributions to merely bounded second or fourth moment. As an illustration of this principle, we focus on robust estimation of the low-rank matrix $Θ^*$ from the trace regression model $Y=Tr (Θ^{*T}X) +ε$. It encompasses four popular problems: sparse linear models, compressed sensing, matrix completion and multi-task regression. We propose to…
A regularized risk minimization procedure for regression function estimation is introduced that achieves near optimal accuracy and confidence under general conditions, including heavy-tailed predictor and response variables. The procedure is based on median-of-means tournaments, introduced by the authors in [8]. It is shown that the new procedure outperforms standard regularized empirical risk minimization procedures such as lasso or slope in heavy-tailed problems.
Many complex disease syndromes such as asthma consist of a large number of highly related, rather than independent, clinical phenotypes, raising a new technical challenge in identifying genetic variations associated simultaneously with correlated traits. In this study, we propose a new statistical framework called graph-guided fused lasso (GFlasso) to address this issue in a principled way. Our approach explicitly represents the dependency structure among the quantitative traits as a network, and leverages this trait network to encode structured regularizations in a multivariate regression mod…
Zhejiang University（浙江大学）；Shenzhen University（深圳大学）；The Hong Kong Polytechnic University（香港理工大学）；Chinese Academy of Sciences（中国科学院）
In this paper, we discuss the statistical properties of the $\ell_q$ optimization methods $(0<q\leq 1)$, including the $\ell_q$ minimization method and the $\ell_q$ regularization method, for estimating a sparse parameter from noisy observations in high-dimensional linear regression with either a deterministic or random design. For this purpose, we introduce a general $q$-restricted eigenvalue condition (REC) and provide its sufficient conditions in terms of several widely-used regularity conditions such as sparse eigenvalue condition, restricted isometry property, and mutual incoherence prope…
We study the problem of Robust Least Squares Regression (RLSR) where several response variables can be adversarially corrupted. More specifically, for a data matrix X \in R^{p x n} and an underlying model w*, the response vector is generated as y = X'w* + b where b \in R^n is the corruption vector supported over at most C.n coordinates. Existing exact recovery results for RLSR focus solely on L1-penalty based convex formulations and impose relatively strict model assumptions such as requiring the corruptions b to be selected independently of X. In this work, we study a simple hard-thresholding…
We present a general architecture for the acquisition of ensembles of correlated signals. The signals are multiplexed onto a single line by mixing each one against a different code and then adding them together, and the resulting signal is sampled at a high rate. We show that if the $M$ signals, each bandlimited to $W/2$ Hz, can be approximated by a superposition of $R < M$ underlying signals, then the ensemble can be recovered by sampling at a rate within a logarithmic factor of $RW$ (as compared to the Nyquist rate of $MW$). This sampling theorem shows that the correlation structure of the s…
We consider high dimensional sparse regression, and develop strategies able to deal with arbitrary -- possibly, severe or coordinated -- errors in the covariance matrix $X$. These may come from corrupted data, persistent experimental errors, or malicious respondents in surveys/recommender systems, etc. Such non-stochastic error-in-variables problems are notoriously difficult to treat, and as we demonstrate, the problem is particularly pronounced in high-dimensional settings where the primary goal is {\em support recovery} of the sparse regressor. We develop algorithms for support recovery in s…
We formulate sparse support recovery as a salient set identification problem and use information-theoretic analyses to characterize the recovery performance and sample complexity. We consider a very general model where we are not restricted to linear models or specific distributions. We state non-asymptotic bounds on recovery probability and a tight mutual information formula for sample complexity. We evaluate our bounds for applications such as sparse linear regression and explicitly characterize effects of correlation or noisy features on recovery performance. We show improvements upon previ…
Random non-linear Fourier features have recently shown remarkable performance in a wide-range of regression and classification applications. Motivated by this success, this article focuses on a sparse non-linear Fourier feature (NFF) model. We provide a characterization of the sufficient number of data points that guarantee perfect recovery of the unknown parameters with high-probability. In particular, we show how the sufficient number of data points depends on the kernel matrix associated with the probability distribution function of the input data. We compare our results with the recoverabi…
Indian Institute of Technology Madras（印度理工学院马德拉斯分校）
Recovering the support of sparse vectors in underdetermined linear regression models, \textit{aka}, compressive sensing is important in many signal processing applications. High SNR consistency (HSC), i.e., the ability of a support recovery technique to correctly identify the support with increasing signal to noise ratio (SNR) is an increasingly popular criterion to qualify the high SNR optimality of support recovery techniques. The HSC results available in literature for support recovery techniques applicable to underdetermined linear regression models like least absolute shrinkage and select…
In this paper we introduce a new optimization formulation for sparse regression and compressed sensing, called CLOT (Combined L-One and Two), wherein the regularizer is a convex combination of the $\ell_1$- and $\ell_2$-norms. This formulation differs from the Elastic Net (EN) formulation, in which the regularizer is a convex combination of the $\ell_1$- and $\ell_2$-norm squared. It is shown that, in the context of compressed sensing, the EN formulation does not achieve robust recovery of sparse vectors, whereas the new CLOT formulation achieves robust recovery. Also, like EN but unlike LASSO…
In this note we compare two recently proposed semidefinite relaxations for the sparse linear regression problem by Pilanci, Wainwright and El Ghaoui (Sparse learning via boolean relaxations, 2015) and Dong, Chen and Linderoth (Relaxation vs. Regularization A conic optimization perspective of statistical variable selection, 2015). We focus on the cardinality constrained formulation, and prove that the relaxation proposed by Dong, etc. is theoretically no weaker than the one proposed by Pilanci, etc. Therefore any sufficient condition of exact recovery derived by Pilanci can be readily applied t…
We apply the OSCAR (octagonal selection and clustering algorithms for regression) in recovering group-sparse matrices (two-dimensional---2D---arrays) from compressive measurements. We propose a 2D version of OSCAR (2OSCAR) consisting of the $\ell_1$ norm and the pair-wise $\ell_{\infty}$ norm, which is convex but non-differentiable. We show that the proximity operator of 2OSCAR can be computed based on that of OSCAR. The 2OSCAR problem can thus be efficiently solved by state-of-the-art proximal splitting algorithms. Experiments on group-sparse 2D array recovery show that 2OSCAR regularization …
In this paper, we study a new notion of scaled minimaxity for sparse estimation in high-dimensional linear regression model. We present more optimistic lower bounds than the one given by the classical minimax theory and hence improve on existing results. We recover sharp results for the global minimaxity as a consequence of our study. Fixing the scale of the signal-to-noise ratio, we prove that the estimation error can be much smaller than the global minimax error. We construct a new optimal estimator for the scaled minimax sparse estimation. An optimal adaptive procedure is also described.
Consider the use of $\ell_{1}/\ell_{\infty}$-regularized regression for joint estimation of a $\pdim \times \numreg$ matrix of regression coefficients. We analyze the high-dimensional scaling of $\ell_1/\ell_\infty$-regularized quadratic programming, considering both consistency in $\ell_\infty$-norm, and variable selection. We begin by establishing bounds on the $\ell_\infty$-error as well sufficient conditions for exact variable selection for fixed and random designs. Our second set of results applies to $\numreg = 2$ linear regression problems with standard Gaussian designs whose supports o…
Many state-of-the-art machine learning models such as deep neural networks have recently shown to be vulnerable to adversarial perturbations, especially in classification tasks. Motivated by adversarial machine learning, in this paper we investigate the robustness of sparse regression models with strongly correlated covariates to adversarially designed measurement noises. Specifically, we consider the family of ordered weighted $\ell_1$ (OWL) regularized regression methods and study the case of OSCAR (octagonal shrinkage clustering algorithm for regression) in the adversarial setting. Under a …
Principal loading analysis is a dimension reduction method that discards variables which have only a small distorting effect on the covariance matrix. As a special case, principal loading analysis discards variables that are not correlated with the remaining ones. In multivariate linear regression on the other hand, predictors that are neither correlated with both the remaining predictors nor with the dependent variables have a regression coefficients equal to zero. Hence, if the goal is to select a number of predictors, variables that do not correlate are discarded as it is also done in princ…
In this paper, we consider the problem of recovering a sparse signal from noisy linear measurements using the so called LASSO formulation. We assume a correlated Gaussian design matrix with additive Gaussian noise. We precisely analyze the high dimensional asymptotic performance of the LASSO under correlated design matrices using the Convex Gaussian Min-max Theorem (CGMT). We define appropriate performance measures such as the mean-square error (MSE), probability of support recovery, element error rate (EER) and cosine similarity. Numerical simulations are presented to validate the derived the…
Infrastructure recovery time estimation is critical to disaster management and planning. Inspired by recent resilience planning initiatives, we consider a situation where experts are asked to estimate the time for different infrastructure systems to recover to certain functionality levels after a scenario hazard event. We propose a methodological framework to use expert-elicited data to estimate the expected recovery time curve of a particular infrastructure system. This framework uses the Gaussian process regression (GPR) to capture the experts' estimation-uncertainty and satisfy known physic…
Log-symmetric regression models are particularly useful when the response variable is continuous, strictly positive and asymmetric. In this paper, we proposed a class of log-symmetric regression models in the context of correlated errors. The proposed models provide a novel alternative to the existing log-symmetric regression models due to its flexibility in accommodating correlation. We discuss some properties, parameter estimation by the conditional maximum likelihood method and goodness of fit of the proposed model. We also provide expressions for the observed Fisher information matrix. A M…
Traditionally, the least squares regression is mainly concerned with studying the effects of individual predictor variables, but strongly correlated variables generate multicollinearity which makes it difficult to study their effects. Existing methods for handling multicollinearity such as ridge regression are complicated. To resolve the multicollinearity issue without abandoning the simple least squares regression, for situations where predictor variables are in groups with strong within-group correlations but weak between-group correlations, we propose to study the effects of the groups with…
Considering parallel tempering and comparing post-treatment procedures in Bayesian Profile Regression Models for a survival outcome and correlated exposures
Autorité de Sûreté Nucléaire et de Radioprotection (ASNR)（核安全与辐射防护局）；PSE-SANTE/SESANE/LEPID；Université Paris Cité（巴黎西岱大学）；CNRS, Inserm, P-MIM, BioSTM（法国国家科学研究中心、INSERM、P-MIM、BioSTM）
We consider the problem of efficient statistical inference for comparing two regression curves estimated from two samples of dependent measurements. Based on a representation of the best pair of linear unbiased estimators in continuous time models as a stochastic integral, an efficient pair of linear unbiased estimators with corresponding optimal designs for finite sample size is constructed. This pair minimises the width of the confidence band for the difference between the estimated curves. We thus extend results readily available in the literature to the case of correlated observations and …
This paper studies optimal designs for linear regression models with correlated effects for single responses. We introduce the concept of rhombic design to reduce the computational complexity and find a semi-algebraic description for the D-optimality of a rhombic design via the Kiefer-Wolfowitz equivalence theorem. Subsequently, we show that the structure of an optimal rhombic design depends directly on the correlation structure of the random coefficients.
This paper discusses the problem of determining optimal designs for regression models, when the observations are dependent and taken on an interval. A complete solution of this challenging optimal design problem is given for a broad class of regression models and covariance kernels. We propose a class of estimators which are only slightly more complicated than the ordinary least-squares estimators. We then demonstrate that we can design the experiments, such that asymptotically the new estimators achieve the same precision as the best linear unbiased estimator computed for the whole trajectory…
We propose a distributed quadratic inference function framework to jointly estimate regression parameters from multiple potentially heterogeneous data sources with correlated vector outcomes. The primary goal of this joint integrative analysis is to estimate covariate effects on all outcomes through a marginal regression model in a statistically and computationally efficient way. We develop a data integration procedure for statistical estimation and inference of regression parameters that is implemented in a fully distributed and parallelized computational scheme. To overcome computational and…
We present a nonparametric method for estimating the value and several derivatives of an unknown, sufficiently smooth real-valued function of real-valued arguments from a finite sample of points, where both the function arguments and the corresponding values are known only up to measurement errors having some assumed distribution and correlation structure. The method, Moving Taylor Bayesian Regression (MOTABAR), uses Bayesian updating to find the posterior mean of the coefficients of a Taylor polynomial of the function at a moving position of interest. When measurement errors are neglected, MO…
In this paper we investigate the problem of designing experiments for series estimators in nonparametric regression models with correlated observations. We use projection based estimators to derive an explicit solution of the best linear oracle estimator in the continuous time model for all Markovian-type error processes. These solutions are then used to construct estimators, which can be calculated from the available data along with their corresponding optimal design points. Our results are illustrated by means of a simulation study, which demonstrates that the new series estimator has a bett…
This paper presents a new approach for trees-based regression, such as simple regression tree, random forest and gradient boosting, in settings involving correlated data. We show the problems that arise when implementing standard trees-based regression models, which ignore the correlation structure. Our new approach explicitly takes the correlation structure into account in the splitting criterion, stopping rules and fitted values in the leaves, which induces some major modifications of standard methodology. The superiority of our new approach over trees-based models that do not account for th…
The problem of estimating censored linear regression models with autocorrelated errors arises in many environmental and social studies. The present work proposes a Bayesian approach to estimate censored regression models with AR(p) errors. The algorithm developed here considers the Gibbs sampler with data augmentation(GDA), in which, at each iteration, both the model parameters and the latent variables are sampled. The data augmentation is achieved from multiple sampling of the latent variables from the corresponding conditional distributions. A suitable variable transformation allows the full…
Measurement error arises through a variety of mechanisms. A rich literature exists on the bias introduced by covariate measurement error and on methods of analysis to address this bias. By comparison, less attention has been given to errors in outcome assessment and non-classical covariate measurement error. We consider an extension of the regression calibration method to settings with errors in a continuous outcome, where the errors may be correlated with prognostic covariates or with covariate measurement error. This method adjusts for the measurement error in the data and can be applied wit…
Medical studies that depend on electronic health records (EHR) data are often subject to measurement error, as the data are not collected to support research questions under study. These data errors, if not accounted for in study analyses, can obscure or cause spurious associations between patient exposures and disease risk. Methodology to address covariate measurement error has been well developed; however, time-to-event error has also been shown to cause significant bias but methods to address it are relatively underdeveloped. More generally, it is possible to observe errors in both the cova…
Testing procedures for assessing a parametric regression model with circular response and $\mathbb{R}^d$-valued covariate are proposed and analyzed in this work both for independent and for spatially correlated data. The test statistics are based on a circular distance comparing a (non-smoothed or smoothed) parametric circular estimator and a nonparametric one. Properly designed bootstrap procedures for calibrating the tests in practice are also presented. Finite sample performance of the tests in different scenarios with independent and spatially correlated samples, is analyzed by simulations…
New York University（纽约大学）；Shanghai Jiao Tong University（上海交通大学）；Fundan University（复旦大学）
This paper studies distributed estimation and support recovery for high-dimensional linear regression model with heavy-tailed noise. To deal with heavy-tailed noise whose variance can be infinite, we adopt the quantile regression loss function instead of the commonly used squared loss. However, the non-smooth quantile loss poses new challenges to high-dimensional distributed estimation in both computation and theoretical development. To address the challenge, we transform the response variable and establish a new connection between quantile regression and ordinary linear regression. Then, we p…
