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arXiv 2101.09986cs.LGcs.AI
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不规则采样临床时间序列的多视图集成学习

Multi-view Integration Learning for Irregularly-sampled Clinical Time Series

Korea University(高丽大学)

Yurim Lee, Eunji Jun, Heung-Il Suk

摘要:

电子健康记录(EHR)数据是稀疏和不规则的,因为它是在不规则的时间间隔记录的,并且在每个观察点测量不同的临床变量。在这项工作中,我们提出了一个多视图的功能集成学习不规则的多元时间序列数据的自注意机制,在一个插补的方式。具体来说,我们设计了一种新的多整合注意模块(MIAM),以提取复杂的信息,不规则的时间序列数据。特别是,我们显式地学习观察值,缺失指标和连续观察之间的时间间隔之间的关系,同时。我们的方法背后的基本原理是使用人类知识,例如在不同情况下测量什么以及何时测量,这些知识间接地反映在数据中。此外,我们构建了一个基于注意力的解码器作为缺失值输入器,它有助于增强预测任务的多视图观察之间的相互关系的表示学习,该任务仅在训练阶段操作。我们通过与最先进的院内死亡率预测方法进行比较,验证了我们的方法在公共MIMIC-III和PhysioNet挑战2012数据集上的有效性。

英文摘要:

Electronic health record (EHR) data is sparse and irregular as it is recorded at irregular time intervals, and different clinical variables are measured at each observation point. In this work, we propose a multi-view features integration learning from irregular multivariate time series data by self-attention mechanism in an imputation-free manner. Specifically, we devise a novel multi-integration attention module (MIAM) to extract complex information inherent in irregular time series data. In particular, we explicitly learn the relationships among the observed values, missing indicators, and time interval between the consecutive observations, simultaneously. The rationale behind our approach is the use of human knowledge such as what to measure and when to measure in different situations, which are indirectly represented in the data. In addition, we build an attention-based decoder as a missing value imputer that helps empower the representation learning of the inter-relations among multi-view observations for the prediction task, which operates at the training phase only. We validated the effectiveness of our method over the public MIMIC-III and PhysioNet challenge 2012 datasets by comparing with and outperforming the state-of-the-art methods for in-hospital mortality prediction.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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