Complementary Capabilities of Photoacoustic Imaging to Existing Optical Ocular Imaging Techniques

Label-free, non-contact, in-vivo ophthalmic imaging using photoacoustic remote sensing microscopy

We present the first label-free, non-contact, in-vivo imaging of the ocular vasculature using photoacoustic remote sensing (PARS) microscopy. Both anterior and posterior segments mouse eye were imaged. Vasculature of iris, sclera and retina tissues were clearly resolved. To best of our knowledge this the first study showing non-contact photoacoustic imaging conducted on in-vivo ocular tissue. We believe that PARS microscopy has the potential to advance the diagnosis and treatment of ocular diseases.

Non-contact, in-vivo, functional, and structural ophthalmic imaging using multimodal photoacoustic remote sensing (PARS) microscopy and optical coherence tomography (OCT)

Early diagnosis of ocular diseases improves the understanding of pathophysiology and helps with accurate monitoring and effective treatment. Advanced multimodal ocular imaging platforms play a crucial role in the visualization of the ocular components and provide clinicians with a valuable tool for evaluating different eye diseases. Here, for the first time, we present a non-contact, multimodal photoacoustic remote sensing (PARS) microscopy and swept-source optical coherence tomography (SS-OCT) for in-vivo functional and structural imaging of the eye. The system provides complementary imaging …

使用光声反转信标的声速分布横截面成像

Cross-sectional imaging of speed-of-sound distribution using photoacoustic reversal beacons

提出基于光声反转信标（PRBs）的声速分布重建方法，仅利用PAT成像模态，通过激发外围PRB产生的光声波实现内部SOS空间采样，并构建线性逆模型进行逐像素重建，显著提升了PAT图像质量。

定量多模态光学相干光声弹性成像

Quantitative Multi-Modal Optical Coherence Photoacoustic Elastography

提出结合光学相干断层扫描（OCT）和光声断层扫描（PAT）的多模态弹性成像框架，通过混合反演算法融合互补信息，在硅胶体模上实现更高信噪比和更准确的刚度估计。

利用可见光光声检眼镜和近红外二区光学相干断层扫描对小鼠眼睛进行多模态成像

Multimodal imaging of the mouse eye using visible light photoacoustic ophthalmoscopy and near-infrared-II optical coherence tomography

本研究结合玫瑰红增强的可见光PAOM与NIR-II OCT，并开发3D打印眼模和小鼠平台，实现小鼠眼深层结构的多模态无创成像。

结合ULM、光声成像与平面矩阵阵列实现三维共配准的灌注与氧合同步成像

Simultaneous 3D co-registered perfusion and oxygenation with ULM, photoacoustic imaging, and a planar matrix array

本研究开发了基于平面超声矩阵阵列的双模态成像平台，同步实现共配准的三维组织氧合与微血管灌注成像，经体外仿体与小鼠体内验证，为相关生物医学研究奠定基础。