Weakly Supervised 3D Classification of Chest CT using Aggregated Multi-Resolution Deep Segmentation Features
Universitat de Girona（赫罗纳大学）；Université de Bourgogne（勃艮第大学）；Università degli studi di Cassino（卡西诺大学）；Duke University School of Medicine（杜克大学医学院）；Duke University（杜克大学）
Anindo Saha, Fakrul I. Tushar, Khrystyna Faryna, Vincent M. D'Anniballe, Rui Hou, Maciej A. Mazurowski, Geoffrey D. Rubin, Joseph Y. Lo
备注：
Accepted to 2020 SPIE Medical Imaging: Computer-Aided Diagnosis [oral presentation]
Weakly supervised disease classification of CT imaging suffers from poor localization owing to case-level annotations, where even a positive scan can hold hundreds to thousands of negative slices along multiple planes. Furthermore, although deep learning segmentation and classification models extract distinctly unique combinations of anatomical features from the same target class(es), they are typically seen as two independent processes in a computer-aided diagnosis (CAD) pipeline, with little to no feature reuse. In this research, we propose a medical classifier that leverages the semantic structural concepts learned via multi-resolution segmentation feature maps, to guide weakly supervised 3D classification of chest CT volumes. Additionally, a comparative analysis is drawn across two different types of feature aggregation to explore the vast possibilities surrounding feature fusion. Using a dataset of 1593 scans labeled on a case-level basis via rule-based model, we train a dual-stage convolutional neural network (CNN) to perform organ segmentation and binary classification of four representative diseases (emphysema, pneumonia/atelectasis, mass and nodules) in lungs. The baseline model, with separate stages for segmentation and classification, results in AUC of 0.791. Using identical hyperparameters, the connected architecture using static and dynamic feature aggregation improves performance to AUC of 0.832 and 0.851, respectively. This study advances the field in two key ways. First, case-level report data is used to weakly supervise a 3D CT classifier of multiple, simultaneous diseases for an organ. Second, segmentation and classification models are connected with two different feature aggregation strategies to enhance the classification performance.
The University of Texas at Arlington（德克萨斯大学阿灵顿分校）；Tencent AI Lab（腾讯人工智能实验室）
Chest X-rays is one of the most commonly available and affordable radiological examinations in clinical practice. While detecting thoracic diseases on chest X-rays is still a challenging task for machine intelligence, due to 1) the highly varied appearance of lesion areas on X-rays from patients of different thoracic disease and 2) the shortage of accurate pixel-level annotations by radiologists for model training. Existing machine learning methods are unable to deal with the challenge that thoracic diseases usually happen in localized disease-specific areas. In this article, we propose a weak…
Deep Convolutional Neural Networks have proven effective in solving the task of semantic segmentation. However, their efficiency heavily relies on the pixel-level annotations that are expensive to get and often require domain expertise, especially in medical imaging. Weakly supervised semantic segmentation helps to overcome these issues and also provides explainable deep learning models. In this paper, we propose a novel approach to the semantic segmentation of medical chest X-ray images with only image-level class labels as supervision. We improve the disease localization accuracy by combinin…
We consider the problem of abnormality localization for clinical applications. While deep learning has driven much recent progress in medical imaging, many clinical challenges are not fully addressed, limiting its broader usage. While recent methods report high diagnostic accuracies, physicians have concerns trusting these algorithm results for diagnostic decision-making purposes because of a general lack of algorithm decision reasoning and interpretability. One potential way to address this problem is to further train these models to localize abnormalities in addition to just classifying them…
Anatomy-Structured Hierarchical MIL for Weakly-Supervised Thoracic Disease Detection in Chest X-rays
Ewha Womans University（梨花女子大学）；Ewha Medical Artificial Intelligence Research Institute（梨花女子大学医学人工智能研究所）；REMEDI Inc.（瑞美迪公司）；Ewha Womans University Seoul Hospital（梨花女子大学首尔医院）
National Institutes of Health, Clinical Center（美国国立卫生研究院临床中心）；Ping An Technology Co., Ltd.（平安科技有限公司）
In this work, we exploit the task of joint classification and weakly supervised localization of thoracic diseases from chest radiographs, with only image-level disease labels coupled with disease severity-level (DSL) information of a subset. A convolutional neural network (CNN) based attention-guided curriculum learning (AGCL) framework is presented, which leverages the severity-level attributes mined from radiology reports. Images in order of difficulty (grouped by different severity-levels) are fed to CNN to boost the learning gradually. In addition, highly confident samples (measured by cla…
The University of Texas at Austin（德克萨斯大学奥斯汀分校）；Weill Cornell Medical College（威尔康奈尔医学院）
Before the recent success of deep learning methods for automated medical image analysis, practitioners used handcrafted radiomic features to quantitatively describe local patches of medical images. However, extracting discriminative radiomic features relies on accurate pathology localization, which is difficult to acquire in real-world settings. Despite advances in disease classification and localization from chest X-rays, many approaches fail to incorporate clinically-informed domain knowledge. For these reasons, we propose a Radiomics-Guided Transformer (RGT) that fuses \textit{global} image…
Accurate abnormality localization in chest X-rays (CXR) can benefit the clinical diagnosis of various thoracic diseases. However, the lesion-level annotation can only be performed by experienced radiologists, and it is tedious and time-consuming, thus difficult to acquire. Such a situation results in a difficulty to develop a fully-supervised abnormality localization system for CXR. In this regard, we propose to train the CXR abnormality localization framework via a weakly semi-supervised strategy, termed Point Beyond Class (PBC), which utilizes a small number of fully annotated CXRs with lesi…
Given image labels as the only supervisory signal, we focus on harvesting, or mining, thoracic disease localizations from chest X-ray images. Harvesting such localizations from existing datasets allows for the creation of improved data sources for computer-aided diagnosis and retrospective analyses. We train a convolutional neural network (CNN) for image classification and propose an attention mining (AM) strategy to improve the model's sensitivity or saliency to disease patterns. The intuition of AM is that once the most salient disease area is blocked or hidden from the CNN model, it will pa…
Carnegie Mellon University（卡内基梅隆大学）；University of Pennsylvania（宾夕法尼亚大学）
We present a weakly supervised deep learning model for classifying thoracic diseases and identifying abnormalities in chest radiography. In this work, instead of learning from medical imaging data with region-level annotations, our model was merely trained on imaging data with image-level labels to classify diseases, and is able to identify abnormal image regions simultaneously. Our model consists of a customized pooling structure and an adaptive DenseNet front-end, which can effectively recognize possible disease features for classification and localization tasks. Our method has been validate…
The University of Hong Kong（香港大学）；University of Chinese Academy of Sciences（中国科学院大学）
Locating lesions is important in the computer-aided diagnosis of X-ray images. However, box-level annotation is time-consuming and laborious. How to locate lesions accurately with few, or even without careful annotations is an urgent problem. Although several works have approached this problem with weakly-supervised methods, the performance needs to be improved. One obstacle is that general weakly-supervised methods have failed to consider the characteristics of X-ray images, such as the highly-structural attribute. We therefore propose the Cross-chest Graph (CCG), which improves the performan…
Nanjing University（南京大学）；Drum Tower Hospital, Nanjing University（南京大学医学院附属鼓楼医院）；Chinese Academy of Medical Sciences and Peking Union Medical College（中国医学科学院北京协和医学院）
The chest X-Ray (CXR) is the one of the most common clinical exam used to diagnose thoracic diseases and abnormalities. The volume of CXR scans generated daily in hospitals is huge. Therefore, an automated diagnosis system able to save the effort of doctors is of great value. At present, the applications of artificial intelligence in CXR diagnosis usually use pattern recognition to classify the scans. However, such methods rely on labeled databases, which are costly and usually have large error rates. In this work, we built a database containing more than 12,000 CXR scans and radiological repo…
Department of Radiology and Imaging Sciences, Clinical Center（临床中心放射学与影像科学系）
The chest X-ray is one of the most commonly accessible radiological examinations for screening and diagnosis of many lung diseases. A tremendous number of X-ray imaging studies accompanied by radiological reports are accumulated and stored in many modern hospitals' Picture Archiving and Communication Systems (PACS). On the other side, it is still an open question how this type of hospital-size knowledge database containing invaluable imaging informatics (i.e., loosely labeled) can be used to facilitate the data-hungry deep learning paradigms in building truly large-scale high precision compute…
Localization of chest pathologies in chest X-ray images is a challenging task because of their varying sizes and appearances. We propose a novel weakly supervised method to localize chest pathologies using class aware deep multiscale feature learning. Our method leverages intermediate feature maps from CNN layers at different stages of a deep network during the training of a classification model using image level annotations of pathologies. During the training phase, a set of \emph{layer relevance weights} are learned for each pathology class and the CNN is optimized to perform pathology class…
MILA（蒙特利尔学习算法研究所）；Université de Montréal（蒙特利尔大学）；Imagia Inc.（Imagia公司）；School of Computing Science, Simon Fraser University（西蒙弗雷泽大学计算科学学院）
The scarcity of richly annotated medical images is limiting supervised deep learning based solutions to medical image analysis tasks, such as localizing discriminatory radiomic disease signatures. Therefore, it is desirable to leverage unsupervised and weakly supervised models. Most recent weakly supervised localization methods apply attention maps or region proposals in a multiple instance learning formulation. While attention maps can be noisy, leading to erroneously highlighted regions, it is not simple to decide on an optimal window/bag size for multiple instance learning approaches. In th…
HIDSS4Health - Helmholtz Information and Data Science School for Health（HIDSS4Health——亥姆霍兹健康信息与数据科学学院）；Karlsruhe Institute of Technology（卡尔斯鲁厄理工学院）；German Cancer Research Center Heidelberg（海德堡德国癌症研究中心）
The lack of fine-grained annotations hinders the deployment of automated diagnosis systems, which require human-interpretable justification for their decision process. In this paper, we address the problem of weakly supervised identification and localization of abnormalities in chest radiographs. To that end, we introduce a novel loss function for training convolutional neural networks increasing the \emph{localization confidence} and assisting the overall \emph{disease identification}. The loss leverages both image- and patch-level predictions to generate auxiliary supervision. Rather than fo…
Instance level detection of thoracic diseases or abnormalities are crucial for automatic diagnosis in chest X-ray images. Most existing works on chest X-rays focus on disease classification and weakly supervised localization. In order to push forward the research on disease classification and localization on chest X-rays. We provide a new benchmark called ChestX-Det10, including box-level annotations of 10 categories of disease/abnormality of $\sim$ 3,500 images. The annotations are located at https://github.com/Deepwise-AILab/ChestX-Det10-Dataset.
Computer-aided techniques may lead to more accurate and more acces-sible diagnosis of thorax diseases on chest radiography. Despite the success of deep learning-based solutions, this task remains a major challenge in smart healthcare, since it is intrinsically a weakly supervised learning problem. In this paper, we incorporate the attention mechanism into a deep convolutional neural network, and thus propose the ChestNet model to address effective diagnosis of thorax diseases on chest radiography. This model consists of two branches: a classification branch serves as a uniform feature extracti…
Weakly Supervised Anomaly Detection for Chest X-Ray Image
School of Artificial Intelligence, Beijing University of Posts and Telecommunications（北京邮电大学人工智能学院）；College of Information and Engineering, Capital Normal University（首都师范大学信息与工程学院）；Peking University Third Hospital（北京大学第三医院）
University of Pittsburgh（匹兹堡大学）；University of Pittsburgh Medical Center（匹兹堡大学医学中心）
Creating a large-scale dataset of abnormality annotation on medical images is a labor-intensive and costly task. Leveraging weak supervision from readily available data such as radiology reports can compensate lack of large-scale data for anomaly detection methods. However, most of the current methods only use image-level pathological observations, failing to utilize the relevant anatomy mentions in reports. Furthermore, Natural Language Processing (NLP)-mined weak labels are noisy due to label sparsity and linguistic ambiguity. We propose an Anatomy-Guided chest X-ray Network (AGXNet) to addr…
Localizing thoracic diseases on chest X-ray plays a critical role in clinical practices such as diagnosis and treatment planning. However, current deep learning based approaches often require strong supervision, e.g. annotated bounding boxes, for training such systems, which is infeasible to harvest in large-scale. We present Probabilistic Class Activation Map (PCAM) pooling, a novel global pooling operation for lesion localization with only image-level supervision. PCAM pooling explicitly leverages the excellent localization ability of CAM during training in a probabilistic fashion. Experimen…
Deep Omni-supervised Learning for Rib Fracture Detection from Chest Radiology Images
Imsight AI Research Lab（Imsight AI 研究实验室）；The Hong Kong University of Science and Technology（香港科技大学）；HKUST Shenzhen-Hong Kong Collaborative Innovation Research Institute（香港科技大学深圳-香港协同创新研究院）；The Chinese University of Hong Kong（香港中文大学）
Technical University of Munich（慕尼黑工业大学）；Johns Hopkins University（约翰斯·霍普金斯大学）
Neural networks are proven to be remarkably successful for classification and diagnosis in medical applications. However, the ambiguity in the decision-making process and the interpretability of the learned features is a matter of concern. In this work, we propose a method for improving the feature interpretability of neural network classifiers. Initially, we propose a baseline convolutional neural network with state of the art performance in terms of accuracy and weakly supervised localization. Subsequently, the loss is modified to integrate robustness to adversarial examples into the trainin…
University of New South Wales（新南威尔士大学）；Stanford University（斯坦福大学）
The novel coronavirus disease 2019 (COVID-19) has been spreading rapidly around the world and caused significant impact on the public health and economy. However, there is still lack of studies on effectively quantifying the lung infection caused by COVID-19. As a basic but challenging task of the diagnostic framework, segmentation plays a crucial role in accurate quantification of COVID-19 infection measured by computed tomography (CT) images. To this end, we proposed a novel deep learning algorithm for automated segmentation of multiple COVID-19 infection regions. Specifically, we use the Ag…
National Center for Biotechnology Information (NCBI)（美国国家生物技术信息中心）；National Library of Medicine (NLM)（美国国家医学图书馆）；National Institutes of Health (NIH)（美国国立卫生研究院）；Weill Cornell Medicine（威尔康奈尔医学院）；University of Texas at Arlington（德克萨斯大学阿灵顿分校）
The latest threat to global health is the COVID-19 outbreak. Although there exist large datasets of chest X-rays (CXR) and computed tomography (CT) scans, few COVID-19 image collections are currently available due to patient privacy. At the same time, there is a rapid growth of COVID-19-relevant articles in the biomedical literature. Here, we present COVID-19-CT-CXR, a public database of COVID-19 CXR and CT images, which are automatically extracted from COVID-19-relevant articles from the PubMed Central Open Access (PMC-OA) Subset. We extracted figures, associated captions, and relevant figure…
The University of Hong Kong（香港大学）；Xidian University（西安电子科技大学）；Sun Yat-Sen University（中山大学）；DeepWise AI Lab（深睿医疗人工智能实验室）
Identifying and locating diseases in chest X-rays are very challenging, due to the low visual contrast between normal and abnormal regions, and distortions caused by other overlapping tissues. An interesting phenomenon is that there exist many similar structures in the left and right parts of the chest, such as ribs, lung fields and bronchial tubes. This kind of similarities can be used to identify diseases in chest X-rays, according to the experience of broad-certificated radiologists. Aimed at improving the performance of existing detection methods, we propose a deep end-to-end module to exp…
Pre-trained models, e.g., from ImageNet, have proven to be effective in boosting the performance of many downstream applications. It is too demanding to acquire large-scale annotations to build such models for medical imaging. Meanwhile, there are numerous clinical data (in the form of images and text reports) stored in the hospital information systems. The paired image-text data from the same patient study could be utilized for the pre-training task in a weakly supervised manner. However, the integrity, accessibility, and amount of such raw data vary across different institutes, e.g., paired …
Image representation is a fundamental task in computer vision. However, most of the existing approaches for image representation ignore the relations between images and consider each input image independently. Intuitively, relations between images can help to understand the images and maintain model consistency over related images, leading to better explainability. In this paper, we consider modeling the image-level relations to generate more informative image representations, and propose ImageGCN, an end-to-end graph convolutional network framework for inductive multi-relational image modelin…
HwaMei Hospital, University of Chinese Academy of Sciences（中国科学院大学华美医院）；Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences（中国科学院大学宁波生命与健康产业研究院）；The University of Hong Kong（香港大学）；Institute of Automation, Chinese Academy of Sciences（中国科学院自动化研究所）；Beihang University（北京航空航天大学）
Locating diseases in chest X-ray images with few careful annotations saves large human effort. Recent works approached this task with innovative weakly-supervised algorithms such as multi-instance learning (MIL) and class activation maps (CAM), however, these methods often yield inaccurate or incomplete regions. One of the reasons is the neglection of the pathological implications hidden in the relationship across anatomical regions within each image and the relationship across images. In this paper, we argue that the cross-region and cross-image relationship, as contextual and compensating in…
To enable a deep learning-based system to be used in the medical domain as a computer-aided diagnosis system, it is essential to not only classify diseases but also present the locations of the diseases. However, collecting instance-level annotations for various thoracic diseases is expensive. Therefore, weakly supervised localization methods have been proposed that use only image-level annotation. While the previous methods presented the disease location as the most discriminative part for classification, this causes a deep network to localize wrong areas for indistinguishable X-ray images. T…
Imsight AI Research Lab（Imsight人工智能研究实验室）；The Chinese University of Hong Kong（香港中文大学）；Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；The Hong Kong University of Science and Technology（香港科技大学）
Most of the existing object detection works are based on the bounding box annotation: each object has a precise annotated box. However, for rib fractures, the bounding box annotation is very labor-intensive and time-consuming because radiologists need to investigate and annotate the rib fractures on a slice-by-slice basis. Although a few studies have proposed weakly-supervised methods or semi-supervised methods, they could not handle different forms of supervision simultaneously. In this paper, we proposed a novel omni-supervised object detection network, which can exploit multiple different f…
In medical imaging, Class-Activation Map (CAM) serves as the main explainability tool by pointing to the region of interest. Since the localization accuracy from CAM is constrained by the resolution of the model's feature map, one may expect that segmentation models, which generally have large feature maps, would produce more accurate CAMs. However, we have found that this is not the case due to task mismatch. While segmentation models are developed for datasets with pixel-level annotation, only image-level annotation is available in most medical imaging datasets. Our experiments suggest that …
Beihang University（北京航空航天大学）；The University of Hong Kong（香港大学）；Deepwise AI Lab（深睿人工智能实验室）；Hwa Mei Hospital, UCAS（中国科学院大学华美医院）；Ningbo Institute of Life and Health Industry, UCAS（中国科学院大学宁波生命与健康产业研究院）；Xidian University（西安电子科技大学）；Northwestern Polytechnical University（西北工业大学）
Although deep learning algorithms have been intensively developed for computer-aided tuberculosis diagnosis (CTD), they mainly depend on carefully annotated datasets, leading to much time and resource consumption. Weakly supervised learning (WSL), which leverages coarse-grained labels to accomplish fine-grained tasks, has the potential to solve this problem. In this paper, we first propose a new large-scale tuberculosis (TB) chest X-ray dataset, namely the tuberculosis chest X-ray attribute dataset (TBX-Att), and then establish an attribute-assisted weakly-supervised framework to classify and …
Tsinghua University（清华大学）；Huazhong University of Science and Technology（华中科技大学）
Segmentation of infected areas in chest CT volumes is of great significance for further diagnosis and treatment of COVID-19 patients. Due to the complex shapes and varied appearances of lesions, a large number of voxel-level labeled samples are generally required to train a lesion segmentation network, which is a main bottleneck for developing deep learning based medical image segmentation algorithms. In this paper, we propose a weakly-supervised lesion segmentation framework by embedding the Generative Adversarial training process into the Segmentation Network, which is called GASNet. GASNet …
Diagnostic imaging often requires the simultaneous identification of a multitude of findings of varied size and appearance. Beyond global indication of said findings, the prediction and display of localization information improves trust in and understanding of results when augmenting clinical workflow. Medical training data rarely includes more than global image-level labels as segmentations are time-consuming and expensive to collect. We introduce an approach to managing these practical constraints by applying a novel architecture which learns at multiple resolutions while generating saliency…
A weakly-supervised semantic segmentation framework with a tied deconvolutional neural network is presented. Each deconvolution layer in the framework consists of unpooling and deconvolution operations. 'Unpooling' upsamples the input feature map based on unpooling switches defined by corresponding convolution layer's pooling operation. 'Deconvolution' convolves the input unpooled features by using convolutional weights tied with the corresponding convolution layer's convolution operation. The unpooling-deconvolution combination helps to eliminate less discriminative features in a feature extr…
The increased availability and accuracy of eye-gaze tracking technology has sparked attention-related research in psychology, neuroscience, and, more recently, computer vision and artificial intelligence. The attention mechanism in artificial neural networks is known to improve learning tasks. However, no previous research has combined the network attention and human attention. This paper describes a gaze-guided class activation mapping (GG-CAM) method to directly regulate the formation of network attention based on expert radiologists' visual attention for the chest X-ray pathology classifica…
Recent advances of deep learning have achieved remarkable performances in various challenging computer vision tasks. Especially in object localization, deep convolutional neural networks outperform traditional approaches based on extraction of data/task-driven features instead of hand-crafted features. Although location information of region-of-interests (ROIs) gives good prior for object localization, it requires heavy annotation efforts from human resources. Thus a weakly supervised framework for object localization is introduced. The term "weakly" means that this framework only uses image-l…
Khulna University of Engineering & Technology (KUET)（库尔纳工程技术大学）
The novel Coronavirus Disease 2019 (COVID-19) is a global pandemic disease spreading rapidly around the world. A robust and automatic early recognition of COVID-19, via auxiliary computer-aided diagnostic tools, is essential for disease cure and control. The chest radiography images, such as Computed Tomography (CT) and X-ray, and deep Convolutional Neural Networks (CNNs), can be a significant and useful material for designing such tools. However, designing such an automated tool is challenging as a massive number of manually annotated datasets are not publicly available yet, which is the core…
Vanderbilt University（范德堡大学）；Vanderbilt University Medical Center（范德堡大学医学中心）
Coronary artery calcium (CAC) is biomarker of advanced subclinical coronary artery disease and predicts myocardial infarction and death prior to age 60 years. The slice-wise manual delineation has been regarded as the gold standard of coronary calcium detection. However, manual efforts are time and resource consuming and even impracticable to be applied on large-scale cohorts. In this paper, we propose the attention identical dual network (AID-Net) to perform CAC detection using scan-rescan longitudinal non-contrast CT scans with weakly supervised attention by only using per scan level labels.…
Christian Brothers University（基督教兄弟大学）；University of Dayton（代顿大学）
With a Coronavirus disease (COVID-19) case count exceeding 10 million worldwide, there is an increased need for a diagnostic capability. The main variables in increasing diagnostic capability are reduced cost, turnaround or diagnosis time, and upfront equipment cost and accessibility. Two candidates for machine learning COVID-19 diagnosis are Computed Tomography (CT) scans and plain chest X-rays. While CT scans score higher in sensitivity, they have a higher cost, maintenance requirement, and turnaround time as compared to plain chest X-rays. The use of portable chest X-radiograph (CXR) is rec…
Australian Institute for Machine Learning, The University of Adelaide（阿德莱德大学澳大利亚机器学习研究所）；Institute for Systems and Robotics, Instituto Superior Tecnico（高等技术学院系统与机器人研究所）
The deployment of automated systems to diagnose diseases from medical images is challenged by the requirement to localise the diagnosed diseases to justify or explain the classification decision. This requirement is hard to fulfil because most of the training sets available to develop these systems only contain global annotations, making the localisation of diseases a weakly supervised approach. The main methods designed for weakly supervised disease classification and localisation rely on saliency or attention maps that are not specifically trained for localisation, or on region proposals tha…
Group activity recognition is the task of understanding the activity conducted by a group of people as a whole in a multi-person video. Existing models for this task are often impractical in that they demand ground-truth bounding box labels of actors even in testing or rely on off-the-shelf object detectors. Motivated by this, we propose a novel model for group activity recognition that depends neither on bounding box labels nor on object detector. Our model based on Transformer localizes and encodes partial contexts of a group activity by leveraging the attention mechanism, and represents a v…
Peng Cheng Laboratory（鹏城实验室）；Sun Yat-sen University（中山大学）；Harbin Institute of Technology, Shenzhen（哈尔滨工业大学（深圳））；Shenzhen People's Hospital（深圳市人民医院）；Shenzhen Institute of Respiratory Diseases（深圳呼吸疾病研究所）；Peking University Shenzhen Graduate School（北京大学深圳研究生院）
Despite tremendous efforts, it is very challenging to generate a robust model to assist in the accurate quantification assessment of COVID-19 on chest CT images. Due to the nature of blurred boundaries, the supervised segmentation methods usually suffer from annotation biases. To support unbiased lesion localisation and to minimise the labeling costs, we propose a data-driven framework supervised by only image-level labels. The framework can explicitly separate potential lesions from original images, with the help of a generative adversarial network and a lesion-specific decoder. Experiments o…
Johns Hopkins University（约翰斯·霍普金斯大学）；Technical University of Munich（慕尼黑工业大学）；Kyung Hee University（庆熙大学）
Convolutional neural networks are showing promise in the automatic diagnosis of thoracic pathologies on chest x-rays. Their black-box nature has sparked many recent works to explain the prediction via input feature attribution methods (aka saliency methods). However, input feature attribution methods merely identify the importance of input regions for the prediction and lack semantic interpretation of model behavior. In this work, we first identify the semantics associated with internal units (feature maps) of the network. We proceed to investigate the following questions; Does a regression mo…
From Classification to Localization and Clinical Validation: Large-Scale Development of a Deep Learning System for Thoracic Disease Detection on Chest Radiographs in Thailand
Perceptra Co., Ltd.（Perceptra有限公司）；Radiology Department, Faculty of Medicine Siriraj Hospital, Mahidol University（玛希隆大学诗里拉吉医院医学院放射科）；Institute of Field Robotics, King Mongkut’s University of Technology Thonburi（泰国国王科技大学吞武里分校野外机器人研究所）
LASTIG, Univ. Gustave Eiffel, IGN-ENSG（古斯塔夫·埃菲尔大学LASTIG实验室，法国国家地理与林业信息学院）；INRAE, UMR 1202 BIOGECO, Université de Bordeaux（法国国家农业食品与环境研究院，波尔多大学生物地球化学与生态学联合研究中心）；EA G&E Bordeaux INP, Université Bordeaux Montaigne（波尔多蒙田大学，波尔多国立高等电子、计算机、电信、数学与机械学院环境与地理空间工程研究团队）
We propose a new deep learning-based method for estimating the occupancy of vegetation strata from airborne 3D LiDAR point clouds. Our model predicts rasterized occupancy maps for three vegetation strata corresponding to lower, medium, and higher cover. Our weakly-supervised training scheme allows our network to only be supervised with vegetation occupancy values aggregated over cylindrical plots containing thousands of points. Such ground truth is easier to produce than pixel-wise or point-wise annotations. Our method outperforms handcrafted and deep learning baselines in terms of precision b…
