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arXiv 2008.00710cs.CV
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医学图像复杂场景配准和Few-Shot分割的深度互补联合模型

Deep Complementary Joint Model for Complex Scene Registration and Few-shot Segmentation on Medical Images

Southeast University(东南大学);Centre de Recherche en Information Biomédicale Sino-Français (CRIBs)(中法生物医学信息研究中心);Univ Rennes(雷恩大学);Inserm(法国国家健康与医学研究院);LTSI - UMR1099(信号与图像处理实验室)

Yuting He, Tiantian Li, Guanyu Yang, Youyong Kong, Yang Chen, Huazhong Shu, Jean-Louis Coatrieux, Jean-Louis Dillenseger, Shuo Li

摘要:

基于深度学习的医学图像配准和分割联合模型利用互补性(配准的增强数据或弱监督数据、分割的区域约束)在复杂场景和Few-Shot情况下带来相互改进。然而,联合模型的进一步采用受到阻碍:1)增强数据的多样性降低,限制了分割的进一步增强,2)弱监督数据中的未对齐区域干扰训练过程,3)在Few-Shot情况下缺乏基于标签的区域约束限制了配准性能。提出了一种新的深度互补联合模型(DeepRS),用于复杂场景的配准和Few-Shot分割。我们在配准中嵌入扰动因子以增加变形的活跃性,从而保持增强数据的多样性。我们采用逐像素的加权方法来提取对齐置信度图,该置信度图突出了弱监督数据中的对齐区域,从而通过加权来抑制未对齐区域的干扰。分割模型的输出被用来实现基于深度的区域约束,从而减轻了标签的要求,并带来精细的配准。在MM-WHS 2017 Challenge的CT数据集上进行的大量实验显示了我们的DeepRS的巨大优势,其性能优于现有的最先进模型。

英文摘要:

Deep learning-based medical image registration and segmentation joint models utilize the complementarity (augmentation data or weakly supervised data from registration, region constraints from segmentation) to bring mutual improvement in complex scene and few-shot situation. However, further adoption of the joint models are hindered: 1) the diversity of augmentation data is reduced limiting the further enhancement of segmentation, 2) misaligned regions in weakly supervised data disturb the training process, 3) lack of label-based region constraints in few-shot situation limits the registration performance. We propose a novel Deep Complementary Joint Model (DeepRS) for complex scene registration and few-shot segmentation. We embed a perturbation factor in the registration to increase the activity of deformation thus maintaining the augmentation data diversity. We take a pixel-wise discriminator to extract alignment confidence maps which highlight aligned regions in weakly supervised data so the misaligned regions' disturbance will be suppressed via weighting. The outputs from segmentation model are utilized to implement deep-based region constraints thus relieving the label requirements and bringing fine registration. Extensive experiments on the CT dataset of MM-WHS 2017 Challenge show great advantages of our DeepRS that outperforms the existing state-of-the-art models.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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