arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2006.12017q-bio.GNq-bio.PEq-bio.QM
收藏

转座因子的动力学在遗传序列中产生结构和对称性

Dynamics of transposable elements generates structure and symmetries in genetic sequences

Giampaolo Cristadoro, Mirko Degli Esposti, Eduardo G. Altmann

摘要:

已知基因序列具有非平凡的组成以及它们的组成部分的频率的对称性。最近的研究表明,DNA的对称性和结构在层次上是相互交织的,这表明这两个特征有着共同的起源。然而,导致这种关系的机制尚不清楚。在这里,我们调查了生物学动机的动态进化的基因序列。我们发现,一个亚稳态(长寿)政权出现在序列的对称性和结构交错的方式相匹配的现存基因组。

英文摘要:

Genetic sequences are known to possess non-trivial composition together with symmetries in the frequencies of their components. Recently, it has been shown that symmetry and structure are hierarchically intertwined in DNA, suggesting a common origin for both features. However, the mechanism leading to this relationship is unknown. Here we investigate a biologically motivated dynamics for the evolution of genetic sequences. We show that a metastable (long-lived) regime emerges in which sequences have symmetry and structure interlaced in a way that matches that of extant genomes.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑