We propose a novel deep neural network architecture for normalcy detection in chest X-ray images. This architecture treats the problem as fine-grained binary classification in which the normal cases are well-defined as a class while leaving all other cases in the broad class of abnormal. It employs several components that allow generalization and prevent overfitting across demographics. The model is trained and validated on a large public dataset of frontal chest X-ray images. It is then tested independently on images from a clinical institution of differing patient demographics using a three radiologist consensus for ground truth labeling. The model provides an area under ROC curve of 0.96 when tested on 1271 images. We can automatically remove nearly a third of disease-free chest X-ray screening images from the workflow, without introducing any false negatives (100% sensitivity to disease) thus raising the potential of expediting radiology workflows in hospitals in future.
Chest radiographs are among the most frequently acquired images in radiology and are often the subject of computer vision research. However, most of the models used to classify chest radiographs are derived from openly available deep neural networks, trained on large image-datasets. These datasets routinely differ from chest radiographs in that they are mostly color images and contain several possible image classes, while radiographs are greyscale images and often only contain fewer image classes. Therefore, very deep neural networks, which can represent more complex relationships in image-fea…
National University of Sciences and Technology (NUST)(国立科技大学)
Among various medical imaging tools, chest radiographs are the most important and widely used diagnostic tool for detection of thoracic pathologies. Research is being carried out in order to propose robust automatic diagnostic tool for detection of pathologies from chest radiographs. Artificial Intelligence techniques especially deep learning methodologies have found to be giving promising results in automating the field of medicine. Lot of research has been done for automatic and fast detection of pneumothorax from chest radiographs while proposing several frameworks based on artificial intel…
Lung nodules can be an alarming precursor to potential lung cancer. Missed nodule detections during chest radiograph analysis remains a common challenge among thoracic radiologists. In this work, we present a multi-task lung nodule detection algorithm for chest radiograph analysis. Unlike past approaches, our algorithm predicts a global-level label indicating nodule presence along with local-level labels predicting nodule locations using a Dual Head Network (DHN). We demonstrate the favorable nodule detection performance that our multi-task formulation yields in comparison to conventional meth…
Technical University of Munich(慕尼黑工业大学);Stanford University(斯坦福大学)
Interpreting chest radiograph, a.ka. chest x-ray, images is a necessary and crucial diagnostic tool used by medical professionals to detect and identify many diseases that may plague a patient. Although the images themselves contain a wealth of valuable information, their usefulness may be limited by how well they are interpreted, especially when the reviewing radiologist may be fatigued or when or an experienced radiologist is unavailable. Research in the use of deep learning models to analyze chest radiographs yielded impressive results where, in some instances, the models outperformed pract…
Total lung volume is an important quantitative biomarker and is used for the assessment of restrictive lung diseases. In this study, we investigate the performance of several deep-learning approaches for automated measurement of total lung volume from chest radiographs. 7621 posteroanterior and lateral view chest radiographs (CXR) were collected from patients with chest CT available. Similarly, 928 CXR studies were chosen from patients with pulmonary function test (PFT) results. The reference total lung volume was calculated from lung segmentation on CT or PFT data, respectively. This dataset …
Lung nodules are commonly missed in chest radiographs. We propose and evaluate P-AnoGAN, an unsupervised anomaly detection approach for lung nodules in radiographs. P-AnoGAN modifies the fast anomaly detection generative adversarial network (f-AnoGAN) by utilizing a progressive GAN and a convolutional encoder-decoder-encoder pipeline. Model training uses only unlabelled healthy lung patches extracted from the Indiana University Chest X-Ray Collection. External validation and testing are performed using healthy and unhealthy patches extracted from the ChestX-ray14 and Japanese Society for Radio…
Beth Israel Deaconess Medical Center(贝斯以色列女执事医疗中心);Harvard Medical School(哈佛医学院);Massachusetts Institute of Technology(麻省理工学院);Philips Research(飞利浦研究院)
Purpose: To develop a machine learning model to classify the severity grades of pulmonary edema on chest radiographs. Materials and Methods: In this retrospective study, 369,071 chest radiographs and associated radiology reports from 64,581 (mean age, 51.71; 54.51% women) patients from the MIMIC-CXR chest radiograph dataset were included. This dataset was split into patients with and without congestive heart failure (CHF). Pulmonary edema severity labels from the associated radiology reports were extracted from patients with CHF as four different ordinal levels: 0, no edema; 1, vascular conges…
In this paper, we present a deep learning-based image processing technique for extraction of bone structures in chest radiographs using a U-Net FCNN. The U-Net was trained to accomplish the task in a fully supervised setting. To create the training image pairs, we employed simulated X-Ray or Digitally Reconstructed Radiographs (DRR), derived from 664 CT scans belonging to the LIDC-IDRI dataset. Using HU based segmentation of bone structures in the CT domain, a synthetic 2D "Bone x-ray" DRR is produced and used for training the network. For the reconstruction loss, we utilize two loss functions…
Imaging Biomarkers and Computer-aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center(美国国立卫生研究院临床中心放射学与成像科学部成像生物标志物和计算机辅助诊断实验室);Ping An Technology Co., Ltd.(平安科技有限公司)
Dual-energy (DE) chest radiography provides the capability of selectively imaging two clinically relevant materials, namely soft tissues, and osseous structures, to better characterize a wide variety of thoracic pathology and potentially improve diagnosis in posteroanterior (PA) chest radiographs. However, DE imaging requires specialized hardware and a higher radiation dose than conventional radiography, and motion artifacts sometimes happen due to involuntary patient motion. In this work, we learn the mapping between conventional radiographs and bone suppressed radiographs. Specifically, we p…
Chest radiographs are frequently used to verify the correct intubation of patients in the emergency room. Fast and accurate identification and localization of the endotracheal (ET) tube is critical for the patient. In this study we propose a novel automated deep learning scheme for accurate detection and segmentation of the ET tubes. Development of automatic systems using deep learning networks for classification and segmentation require large annotated data which is not always available. Here we present an approach for synthesizing ET tubes in real X-ray images. We suggest a method for traini…
Deformable Image Registration of Dark-Field Chest Radiographs for Local Lung Signal Change Assessment
Technical University of Munich(慕尼黑工业大学);Munich Institute for Biomedical Engineering, Technical University of Munich(慕尼黑工业大学慕尼黑生物医学工程研究所);Klinikum rechts der Isar, Technical University of Munich(慕尼黑工业大学右岸医院);TUM University Hospital(慕尼黑工业大学大学医院);Philips Innovative Technologies(飞利浦创新技术公司);Institute for Advanced Study, Technical University of Munich(慕尼黑工业大学高等研究院)
Chest radiographs are commonly performed low-cost exams for screening and diagnosis. However, radiographs are 2D representations of 3D structures causing considerable clutter impeding visual inspection and automated image analysis. Here, we propose a Fully Convolutional Network to suppress, for a specific task, undesired visual structure from radiographs while retaining the relevant image information such as lung-parenchyma. The proposed algorithm creates reconstructed radiographs and ground-truth data from high resolution CT-scans. Results show that removing visual variation that is irrelevan…
Dartmouth College(达特茅斯学院);Dartmouth-Hitchcock Medical Center(达特茅斯-希区柯克医疗中心)
Background: Deep learning has great potential to assist with detecting and triaging critical findings such as pneumoperitoneum on medical images. To be clinically useful, the performance of this technology still needs to be validated for generalizability across different types of imaging systems. Materials and Methods: This retrospective study included 1,287 chest X-ray images of patients who underwent initial chest radiography at 13 different hospitals between 2011 and 2019. The chest X-ray images were labelled independently by four radiologist experts as positive or negative for pneumoperito…
Large, labeled datasets have driven deep learning methods to achieve expert-level performance on a variety of medical imaging tasks. We present CheXpert, a large dataset that contains 224,316 chest radiographs of 65,240 patients. We design a labeler to automatically detect the presence of 14 observations in radiology reports, capturing uncertainties inherent in radiograph interpretation. We investigate different approaches to using the uncertainty labels for training convolutional neural networks that output the probability of these observations given the available frontal and lateral radiogra…
The abundance of overlapping anatomical structures appearing in chest radiographs can reduce the performance of lung pathology detection by automated algorithms (CAD) as well as the human reader. In this paper, we present a deep learning based image processing technique for enhancing the contrast of soft lung structures in chest radiographs using Fully Convolutional Neural Networks (FCNN). Two 2D FCNN architectures were trained to accomplish the task: The first performs 2D lung segmentation which is used for normalization of the lung area. The second FCNN is trained to extract lung structures.…
We propose an automated method based on deep learning to compute the cardiothoracic ratio and detect the presence of cardiomegaly from chest radiographs. We develop two separate models to demarcate the heart and chest regions in an X-ray image using bounding boxes and use their outputs to calculate the cardiothoracic ratio. We obtain a sensitivity of 0.96 at a specificity of 0.81 with a mean absolute error of 0.0209 on a held-out test dataset and a sensitivity of 0.84 at a specificity of 0.97 with a mean absolute error of 0.018 on an independent dataset from a different hospital. We also compa…
HIDSS4Health - Helmholtz Information and Data Science School for Health(HIDSS4Health——亥姆霍兹健康信息与数据科学学院);Karlsruhe Institute of Technology(卡尔斯鲁厄理工学院);German Cancer Research Center Heidelberg(海德堡德国癌症研究中心)
The lack of fine-grained annotations hinders the deployment of automated diagnosis systems, which require human-interpretable justification for their decision process. In this paper, we address the problem of weakly supervised identification and localization of abnormalities in chest radiographs. To that end, we introduce a novel loss function for training convolutional neural networks increasing the \emph{localization confidence} and assisting the overall \emph{disease identification}. The loss leverages both image- and patch-level predictions to generate auxiliary supervision. Rather than fo…
Indian Institute of Technology Kharagpur(印度理工学院卡哈拉格普尔分校);Apollo Gleneagles Hospital(阿波罗格伦伊格尔斯医院);Intel Technology India Pvt. Ltd.(英特尔技术印度私人有限公司)
Chest radiographs are primarily employed for the screening of cardio, thoracic and pulmonary conditions. Machine learning based automated solutions are being developed to reduce the burden of routine screening on Radiologists, allowing them to focus on critical cases. While recent efforts demonstrate the use of ensemble of deep convolutional neural networks(CNN), they do not take disease comorbidity into consideration, thus lowering their screening performance. To address this issue, we propose a Graph Neural Network (GNN) based solution to obtain ensemble predictions which models the dependen…
Philips Research(飞利浦研究院);Hamburg University of Technology(汉堡工业大学);Philips Healthcare(飞利浦医疗);University of Washington Medical Center(华盛顿大学医学中心)
Pneumothorax is a critical condition that requires timely communication and immediate action. In order to prevent significant morbidity or patient death, early detection is crucial. For the task of pneumothorax detection, we study the characteristics of three different deep learning techniques: (i) convolutional neural networks, (ii) multiple-instance learning, and (iii) fully convolutional networks. We perform a five-fold cross-validation on a dataset consisting of 1003 chest X-ray images. ROC analysis yields AUCs of 0.96, 0.93, and 0.92 for the three methods, respectively. We review the clas…
Institute of Medical Engineering & Science, Massachusetts Institute of Technology(麻省理工学院医学工程与科学研究所);Beth Israel Deaconess Medical Center(贝斯以色列女执事医疗中心);Stanford University(斯坦福大学);Harvard Medical School(哈佛医学院);National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health(美国国立卫生研究院国家医学图书馆国家生物技术信息中心)
Chest radiography is an extremely powerful imaging modality, allowing for a detailed inspection of a patient's thorax, but requiring specialized training for proper interpretation. With the advent of high performance general purpose computer vision algorithms, the accurate automated analysis of chest radiographs is becoming increasingly of interest to researchers. However, a key challenge in the development of these techniques is the lack of sufficient data. Here we describe MIMIC-CXR-JPG v2.0.0, a large dataset of 377,110 chest x-rays associated with 227,827 imaging studies sourced from the B…
Cleveland Clinic London Hospital(伦敦克利夫兰诊所医院);Mid South Essex NHS Foundation Trust(中埃塞克斯南部国民保健服务基金会信托);King’s College Hospital NHS Foundation Trust(国王学院医院国民保健服务基金会信托);London South Bank University(伦敦南岸大学)
Objectives: The present study evaluated the impact of a commercially available explainable AI algorithm in augmenting the ability of clinicians to identify lung cancer on chest X-rays (CXR). Design: This retrospective study evaluated the performance of 11 clinicians for detecting lung cancer from chest radiographs, with and without assistance from a commercially available AI algorithm (red dot, Behold.ai) that predicts suspected lung cancer from CXRs. Clinician performance was evaluated against clinically confirmed diagnoses. Setting: The study analysed anonymised patient data from an NHS hosp…
The Coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China, in early December 2019 and now becoming a pandemic. When COVID-19 patients undergo radiography examination, radiologists can observe the present of radiographic abnormalities from their chest X-ray (CXR) images. In this study, a deep convolutional neural network (CNN) model was proposed to aid radiologists in diagnosing COVID-19 patients. First, this work conducted a comparative study on the performance of modified VGG-16, ResNet-50 and DenseNet-121 to classify CXR images into normal, COVID-19 and viral pneumonia. Th…
National University of Sciences and Technology(国立科技大学);Khalifa University(哈利法大学)
Pulmonary diseases can cause severe respiratory problems, leading to sudden death if not treated timely. Many researchers have utilized deep learning systems to diagnose pulmonary disorders using chest X-rays (CXRs). However, such systems require exhaustive training efforts on large-scale data to effectively diagnose chest abnormalities. Furthermore, procuring such large-scale data is often infeasible and impractical, especially for rare diseases. With the recent advances in incremental learning, researchers have periodically tuned deep neural networks to learn different classification tasks w…
NYU Abu Dhabi(纽约大学阿布扎比分校);NYU Grossman School of Medicine(纽约大学格罗斯曼医学院)
The healthcare domain is characterized by heterogeneous data modalities, such as imaging and physiological data. In practice, the variety of medical data assists clinicians in decision-making. However, most of the current state-of-the-art deep learning models solely rely upon carefully curated data of a single modality. In this paper, we propose a dynamic training approach to learn modality-specific data representations and to integrate auxiliary features, instead of solely relying on a single modality. Our preliminary experiments results for a patient phenotyping task using physiological data…
University of Waterloo(滑铁卢大学);National Research Council Canada(加拿大国家研究委员会)
Building AI models with trustworthiness is important especially in regulated areas such as healthcare. In tackling COVID-19, previous work uses convolutional neural networks as the backbone architecture, which has shown to be prone to over-caution and overconfidence in making decisions, rendering them less trustworthy -- a crucial flaw in the context of medical imaging. In this study, we propose a feature learning approach using Vision Transformers, which use an attention-based mechanism, and examine the representation learning capability of Transformers as a new backbone architecture for medi…
Microsoft Research(微软研究院);University Hospitals Birmingham(伯明翰大学医院)
Chest radiography has been a recommended procedure for patient triaging and resource management in intensive care units (ICUs) throughout the COVID-19 pandemic. The machine learning efforts to augment this workflow have been long challenged due to deficiencies in reporting, model evaluation, and failure mode analysis. To address some of those shortcomings, we model radiological features with a human-interpretable class hierarchy that aligns with the radiological decision process. Also, we propose the use of a data-driven error analysis methodology to uncover the blind spots of our model, provi…
Phu Tho Department of Health(富寿省卫生厅);Vingroup Big Data Institute(Vingroup大数据研究院);VinUniversity(VinUniversity大学);Phu Tho General Hospital(富寿综合医院)
Computer-Aided Diagnosis (CAD) systems for chest radiographs using artificial intelligence (AI) have recently shown a great potential as a second opinion for radiologists. The performances of such systems, however, were mostly evaluated on a fixed dataset in a retrospective manner and, thus, far from the real performances in clinical practice. In this work, we demonstrate a mechanism for validating an AI-based system for detecting abnormalities on X-ray scans, VinDr-CXR, at the Phu Tho General Hospital - a provincial hospital in the North of Vietnam. The AI system was directly integrated into …
Recent advances in deep learning have led to a promising performance in many medical image analysis tasks. As the most commonly performed radiological exam, chest radiographs are a particularly important modality for which a variety of applications have been researched. The release of multiple, large, publicly available chest X-ray datasets in recent years has encouraged research interest and boosted the number of publications. In this paper, we review all studies using deep learning on chest radiographs, categorizing works by task: image-level prediction (classification and regression), segme…
Paul G. Allen School of Computer Science and Engineering(保罗·G·艾伦计算机科学与工程学院)
While deep learning has shown promise in the domain of disease classification from medical images, models based on state-of-the-art convolutional neural network architectures often exhibit performance loss due to dataset shift. Models trained using data from one hospital system achieve high predictive performance when tested on data from the same hospital, but perform significantly worse when they are tested in different hospital systems. Furthermore, even within a given hospital system, deep learning models have been shown to depend on hospital- and patient-level confounders rather than meani…
National Library of Medicine, National Institutes of Health(美国国立卫生研究院国家医学图书馆)
Automated segmentation of tuberculosis (TB)-consistent lesions in chest X-rays (CXRs) using deep learning (DL) methods can help reduce radiologist effort, supplement clinical decision-making, and potentially result in improved patient treatment. The majority of works in the literature discuss training automatic segmentation models using coarse bounding box annotations. However, the granularity of the bounding box annotation could result in the inclusion of a considerable fraction of false positives and negatives at the pixel level that may adversely impact overall semantic segmentation perform…
Lung X-ray images, if processed using statistical and computational methods, can distinguish pneumonia from COVID-19. The present work shows that it is possible to extract lung X-ray characteristics to improve the methods of examining and diagnosing patients with suspected COVID-19, distinguishing them from malaria, dengue, H1N1, tuberculosis, and Streptococcus pneumonia. More precisely, an intelligent computational model was developed to process lung X-ray images and classify whether the image is of a patient with COVID-19. The images were processed and extracted their characteristics. These …
Over the last decade, convolutional neural networks (CNNs) have emerged as the leading algorithms in image classification and segmentation. Recent publication of large medical imaging databases have accelerated their use in the biomedical arena. While training data for photograph classification benefits from aggressive geometric augmentation, medical diagnosis -- especially in chest radiographs -- depends more strongly on feature location. Diagnosis classification results may be artificially enhanced by reliance on radiographic annotations. This work introduces a general pre-processing step fo…
Bharti School of Telecommunications Technology & Management, Indian Institute of Technology Delhi(印度理工学院德里分校巴蒂电信技术与管理学院);Teleradiology Solutions(远程放射学解决方案公司);CSIR-Institute of Genomics and Integrative Biology(CSIR基因组学与整合生物学研究所);Christian Medical College, Vellore(韦洛尔基督教医学院)
A chest radiograph, commonly called chest x-ray (CxR), plays a vital role in the diagnosis of various lung diseases, such as lung cancer, tuberculosis, pneumonia, and many more. Automated segmentation of the lungs is an important step to design a computer-aided diagnostic tool for examination of a CxR. Precise lung segmentation is considered extremely challenging because of variance in the shape of the lung caused by health issues, age, and gender. The proposed work investigates the use of an efficient deep convolutional neural network for accurate segmentation of lungs from CxR. We attempt an…
University of Rochester(罗切斯特大学);Ludwig Maximilian University(路德维希马克西米利安大学)
Chest x-rays are the most common radiology studies for diagnosing lung and heart disease. Hence, a system for automated pre-reporting of pathologic findings on chest x-rays would greatly enhance radiologists' productivity. To this end, we investigate a deep-learning framework with novel training schemes for classification of different thoracic pathology labels from chest x-rays. We use the currently largest publicly available annotated dataset ChestX-ray14 of 112,120 chest radiographs of 30,805 patients. Each image was annotated with either a 'NoFinding' class, or one or more of 14 thoracic pa…
Perelman School of Medicine, University of Pennsylvania(宾夕法尼亚大学佩雷尔曼医学院);Siemens Healthineers(西门子医疗)
Purpose: To leverage volumetric quantification of airspace disease (AD) derived from a superior modality (CT) serving as ground truth, projected onto digitally reconstructed radiographs (DRRs) to: 1) train a convolutional neural network to quantify airspace disease on paired CXRs; and 2) compare the DRR-trained CNN to expert human readers in the CXR evaluation of patients with confirmed COVID-19. Materials and Methods: We retrospectively selected a cohort of 86 COVID-19 patients (with positive RT-PCR), from March-May 2020 at a tertiary hospital in the northeastern USA, who underwent chest CT a…
The image captioning task is increasingly prevalent in artificial intelligence applications for medicine. One important application is clinical report generation from chest radiographs. The clinical writing of unstructured reports is time consuming and error-prone. An automated system would improve standardization, error reduction, time consumption, and medical accessibility. In this paper we demonstrate the importance of domain specific pre-training and propose a modified transformer architecture for the medical image captioning task. To accomplish this, we train a series of modified transfor…
Florida International University(佛罗里达国际大学);Technical University of Munich(慕尼黑工业大学);Stanford University(斯坦福大学)
Chest X-ray radiography is one of the earliest medical imaging technologies and remains one of the most widely-used for diagnosis, screening, and treatment follow up of diseases related to lungs and heart. The literature in this field of research reports many interesting studies dealing with the challenging tasks of bone suppression and organ segmentation but performed separately, limiting any learning that comes with the consolidation of parameters that could optimize both processes. This study, and for the first time, introduces a multitask deep learning model that generates simultaneously t…
University of Alicante(阿利坎特大学);Hospital San Juan de Alicante(阿利坎特圣胡安医院);Regional Ministry of Health, Valencia(瓦伦西亚地区卫生部)
We present a labeled large-scale, high resolution chest x-ray dataset for the automated exploration of medical images along with their associated reports. This dataset includes more than 160,000 images obtained from 67,000 patients that were interpreted and reported by radiologists at Hospital San Juan Hospital (Spain) from 2009 to 2017, covering six different position views and additional information on image acquisition and patient demography. The reports were labeled with 174 different radiographic findings, 19 differential diagnoses and 104 anatomic locations organized as a hierarchical ta…
SHAMSUL: Systematic Holistic Analysis to investigate Medical Significance Utilizing Local interpretability methods in deep learning for chest radiography pathology prediction
Stockholm University(斯德哥尔摩大学);Skatturinn (Iceland Revenue and Customs)(冰岛税务总局(冰岛税收和海关局))
Evaluating the Impact of Radiographic Noise on Chest X-ray Semantic Segmentation and Disease Classification Using a Scalable Noise Injection Framework
The University of Texas Health Science Center at Houston(德克萨斯大学休斯顿健康科学中心);Stanford University School of Medicine(斯坦福大学医学院);Algoverse AI Research(Algoverse AI 研究院)
PURPOSE: This study aimed to develop a deep learning-based tool to detect and localize lung nodules with chest radiographs(CXRs). We expected it to enhance the efficiency of interpreting CXRs and reduce the possibilities of delayed diagnosis of lung cancer. MATERIALS AND METHODS: We collected CXRs from NCKUH database and VBD, an open-source medical image dataset, as our training and validation data. A number of CXRs from the Ministry of Health and Welfare(MOHW) database served as our test data. We built a segmentation model to identify lung areas from CXRs, and sliced them into 16 patches. Phy…
Northwestern University(西北大学);Northwestern Memorial Hospital(西北纪念医院)
Propose: To present DeepCOVID-Fuse, a deep learning fusion model to predict risk levels in patients with confirmed coronavirus disease 2019 (COVID-19) and to evaluate the performance of pre-trained fusion models on full or partial combination of chest x-ray (CXRs) or chest radiograph and clinical variables. Materials and Methods: The initial CXRs, clinical variables and outcomes (i.e., mortality, intubation, hospital length of stay, ICU admission) were collected from February 2020 to April 2020 with reverse-transcription polymerase chain reaction (RT-PCR) test results as the reference standard…
We propose a data collecting and annotation pipeline that extracts information from Vietnamese radiology reports to provide accurate labels for chest X-ray (CXR) images. This can benefit Vietnamese radiologists and clinicians by annotating data that closely match their endemic diagnosis categories which may vary from country to country. To assess the efficacy of the proposed labeling technique, we built a CXR dataset containing 9,752 studies and evaluated our pipeline using a subset of this dataset. With an F1-score of at least 0.9923, the evaluation demonstrates that our labeling tool perform…
Google Health, Google(谷歌健康,谷歌);Apollo Radiology International(阿波罗国际放射医学);Northwestern Medicine(西北医学)
Chest radiography (CXR) is the most widely-used thoracic clinical imaging modality and is crucial for guiding the management of cardiothoracic conditions. The detection of specific CXR findings has been the main focus of several artificial intelligence (AI) systems. However, the wide range of possible CXR abnormalities makes it impractical to build specific systems to detect every possible condition. In this work, we developed and evaluated an AI system to classify CXRs as normal or abnormal. For development, we used a de-identified dataset of 248,445 patients from a multi-city hospital networ…