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arXiv 2002.03073eess.IVcs.CVcs.LG

Bone Suppression on Chest Radiographs With Adversarial Learning

Imaging Biomarkers and Computer-aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center(美国国立卫生研究院临床中心放射学与成像科学部成像生物标志物和计算机辅助诊断实验室);Ping An Technology Co., Ltd.(平安科技有限公司)

Jia Liang, Yuxing Tang, Youbao Tang, Jing Xiao, Ronald M. Summers

英文摘要:

Dual-energy (DE) chest radiography provides the capability of selectively imaging two clinically relevant materials, namely soft tissues, and osseous structures, to better characterize a wide variety of thoracic pathology and potentially improve diagnosis in posteroanterior (PA) chest radiographs. However, DE imaging requires specialized hardware and a higher radiation dose than conventional radiography, and motion artifacts sometimes happen due to involuntary patient motion. In this work, we learn the mapping between conventional radiographs and bone suppressed radiographs. Specifically, we propose to utilize two variations of generative adversarial networks (GANs) for image-to-image translation between conventional and bone suppressed radiographs obtained by DE imaging technique. We compare the effectiveness of training with patient-wisely paired and unpaired radiographs. Experiments show both training strategies yield "radio-realistic'' radiographs with suppressed bony structures and few motion artifacts on a hold-out test set. While training with paired images yields slightly better performance than that of unpaired images when measuring with two objective image quality metrics, namely Structural Similarity Index (SSIM) and Peak Signal-to-Noise Ratio (PSNR), training with unpaired images demonstrates better generalization ability on unseen anteroposterior (AP) radiographs than paired training.

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