Updated to correct typos and add a few new statements including one about the resolution of projectional radiology and one discussing experimental requirements for the desired X-ray source. Totaled at 17 pages with four figures. Submitted to Optics Express for consideration
X-ray imaging allows for a non-invasive image of the internal structure of an object. The most common form of X-ray imaging, projectional radiography, is simply a projection or "shadow" of the object rather than a point-to-point image possible with a lens. This technique fails to take advantage of the resolving capabilities of short-wavelength X rays. Various X-ray microscopes, typically operating with soft X rays (< 10 keV), use focusing X-ray optics to obtain higher resolution images of the internal structure of an object. Due to the short focal length of focusing X-ray optics, it becomes difficult to focus on the internal structure of larger objects in such a way to provide significant magnification to be resolvable. Here we present an imaging mechanism that utilizes two-photon X-ray ghost imaging to produce a true point-to-point image of the internal structure of an object, with the potential to introduce focusing X-ray optics or a scintillator-lens pairing to produce a magnified secondary ghost image. The focusing X-ray optics would image the primary ghost image (which has no physical structure to it) allowing the imaging of internal structures deeper than a standard X-ray microscope would allow. In principle, once some experimental barriers are overcome, this X-ray "ghost microscope" may achieve nanometer spatial resolution and open up new capabilities that would be of interest to the fields of physics, material science, and medical imaging.
Terahertz (THz) wave shows great potential in non-destructive testing, bio detection and cancer imaging. Recent progresses on THz wave near-field probes/apertures enable mechanically raster scanning of an object's surface in the near-field region, while an efficient, non-scanning, non-invasive, deeply sub-diffraction-limited imaging still remains challenging. Here, we demonstrate a THz near-field microscopy using a reconfigurable spintronic THz emitter array (STEA) with computational ghost imaging. By illuminating an object with the reconfigurable STEA in near field and computing the correlati…
In quantum mechanics, entanglement and correlations are not just a mere sporadic curiosity, but rather common phenomena at the basis of an interacting quantum system. In electron microscopy, such concepts have not been extensively explored yet in all their implications; in particular, inelastic scattering can be reanalyzed in terms of correlation between the electron beam and the sample. While classical inelastic scattering simply implies loss of coherence in the electron beam, performing a joint measurement on the electron beam and the sample excitation could restore the coherence and the los…
We demonstrate wavelength-wavelength correlations of classical broad-band amplified spontaneous emission (ASE) photons emitted by an erbium-doped fiber amplifier (EDFA) in a wavelength regime around 1530nm. We then apply these classical correlated photons in the framework of a real-world ghost spectroscopy experiment at a wavelength of 1533nm to acetylene (C2H2) reproducing the characteristic absorption features of the C-H stretch and rotational bands. This proof-of-principle experiment confirms the generalization of an ASE source concept offering an attractive light source for classical ghost…
Conventional imaging at low light level requires hundreds of detected photons per pixel to suppress the Poisson noise for accurate reflectivity inference. In this letter, we propose a high-efficiency photon-limited imaging technique, called first-photon ghost imaging, which recovers image from the first-photon detection by exploiting the physics of low-flux measurements and the framework of ghost imaging. The experimental results demonstrated that it could retrieve an image by only 0.1 photon detection per pixel, which is three orders lower than the conventional imaging technique. The SNR mode…
Temporal ghost diffraction (TGD) is observed by taking two-photon cross-correlation in the configuration of reciprocal two-slit diffraction (2SD) where interference fringes develop on the light source side as opposed to the detector side. To this end, a narrow-band chaotic light source and a gated detector are used in the frequency-time domain, which emulate a randomly pointing incoherent light source and a stationary pinhole detector in the momentum-space domain, respectively. Spectral fringes with visibility that closely follows a sinc function of spectral bandwidth are clear evidence that l…
Characterisation of the signal to noise ratio of 2-photon microscopes
Nanyang Technological University（南洋理工大学）；Singapore Centre for Environmental Life Sciences Engineering (SCELSE)（新加坡环境生命科学工程中心）；Institute for Digital Molecular Analytics and Science (IDMxS)（数字分子分析与科学研究所）；Lee Kong Chian School of Medicine（李光前医学院）；School of Physical and Mathematical Sciences（物理与数学科学学院）
An experiment demonstrating single-pixel single-arm complementary compressive microscopic ghost imaging based on a digital micromirror device (DMD) has been performed. To solve the difficulty of projecting speckles or modulated light patterns onto tiny biological objects, we instead focus the microscopic image onto the DMD. With this system, we have successfully obtained a magnified image of micron-sized objects illuminated by the microscope's own incandescent lamp. The image quality of our scheme is more than an order of magnitude better than that obtained by conventional compressed sensing w…
While transmission electron microscopes (TEM) can achieve a much higher resolution than optical microscopes, they face challenges of damage to samples during the high energy processes involved. Here, we explore using computational ghost imaging techniques in electron microscopy to reduce the total required intensity. The technological lack of the equivalent high-resolution, optical spatial light modulator for electrons means that a different approach needs to be pursued. To this end, we show a beam shaping technique based on the use of a distribution of electrically charged metal needles to st…
We use twin photons generated by spontaneous parametric down conversion (SPDC) to perform temporal ghost imaging of a single time signal. The retrieval of a binary signal containing eight bits is performed with an error rate below 1%.
A thermal ghost imaging scheme between two distant parties is proposed and experimentally demonstrated over long-distance optical fibers. In the scheme, the weak thermal light is split into two paths. Photons in one path are spatially diffused according to their frequencies by a spatial dispersion component, then illuminate the object and record its spatial transmission information. Photons in the other path are temporally diffused by a temporal dispersion component. By the coincidence measurement between photons of two paths, the object can be imaged in a way of ghost imaging, based on the fr…
Remote focusing is widely used in 3D two-photon microscopy and 3D photostimulation because it enables fast axial scanning without moving the objective lens or specimen. However, due to the design constraints of microscope optics, remote focus units are often located in non-telecentric positions in the optical path, leading to significant depth dependent 3D field distortions in the imaging volume. To address this limitation, we characterized 3D field distortions arising from non-telecentric remote focusing and present a method for distortion precompensation. We demonstrate its applicability for…
State Key Laboratory of Precision Spectroscopy, and Hainan Institute, East China Normal University（精密光谱学国家重点实验室和华南研究院，华东师范大学）；Chongqing Key Laboratory of Precision Optics, Chongqing Institute of East China Normal University（精密光学重庆市重点实验室，华东师范大学重庆研究院）；Collaborative Innovation Center of Extreme Optics, Shanxi University（极端光学协同创新中心，山西大学）
Mid-infrared temporal ghost imaging via two-photon structured encoding
East China Normal University（华东师范大学）；Chongqing Institute of East China Normal University（华东师范大学重庆研究院）；Shanxi University（山西大学）；Shanghai Research Center for Quantum Sciences（上海量子科学研究中心）；Guangyang Bay Laboratory
We present an overview of the performances of a plenoptic microscope which combines the high sensitivity of a laser optical feedback imaging setup , the high resolution of optical synthetic aperture and a shot noise limited signal to noise ratio by using acoustic photon tagging. By using an adapted phase filtering, this microscope allows phase drift correction and numerical aberration compensation (defocusing, coma, astigmatism ...). This new kind of microscope seems to be well adapted to make deep imaging through scattering and heterogeneous media.
We describe the apparatus of a fluorescence optical microscope with both single-photon and two-photon non-diffracting light sheets excitation for large volume imaging. With special design to accommodate two different wavelength ranges (visible: 400-700 nm, and near infrared: 800-1200 nm), we combine the line-Bessel sheet (LBS, for single-photon excitation) and the scanning Bessel beam (SBB, for two-photon excitation) light sheet together in a single microscope setup. For a transparent thin sample where the scattering can be ignored, the LBS single-photon excitation is the optimal imaging solut…
East China Normal University（华东师范大学）；Chongqing Institute of East China Normal University（华东师范大学重庆研究院）；Shanxi University（山西大学）；Shanghai Research Center for Quantum Sciences（上海量子科学研究中心）；Guangyang Bay Laboratory
We report on the experimental demonstration of single photon state generation and characterization in an electron microscope. In this aim we have used low intensity relativistic (energy between 60kV and 100 keV) electrons beams focused in a ca 1 nm probe to excite diamond nanoparticles. This triggered individual neutral Nitrogen-vacancies (NV0) centers to emit photon which could be gathered and sent to a Hanbury Brown Twiss intensity interferometer. The detection of a dip in the correlation function at small time delays clearly demonstrates antibunching and thus the creation of non-classical l…
Ghost imaging allows to image an object without directly seeing this object. Origi- nally demonstrated in the spatial domain using classical or entangled-photon sources, it was recently shown that ghost imaging can be transposed into the time domain to detect ultrafast signals with high temporal resolution. Here, using an incoherent supercontinuum light source whose spectral fluctuations are imaged using spectrum- to-time transformation in a dispersive fiber, we experimentally demonstrate magnified ghost imaging in the time domain. Our approach is scalable and allows to overcome the resolution…
A test on quantum mechanics proposed long ago by Karl Popper is reconsidered with further detail and new insight. An ambiguity in the proposal, which turns out to be essential in order to make the test conclusive, is identified and taken into account for the first time. Its implications for recently performed photon experiments [such as in D. V. Strekalov \textit{et al.}, Phys. Rev.\ Lett. {\bf 74}, 3600 (1995)] are briefly analyzed.
Correlated-photon imaging, popularly known as ghost imaging, is a technique whereby an image is formed from light that has never interacted with the object. In ghost imaging experiments two correlated light fields are produced. One of these fields illuminates the object, and the other field is measured by a spatially resolving detector. In the quantum regime, these correlated light fields are produced by entangled photons created by spontaneous parametric down-conversion. To date, all correlated-photon ghost-imaging experiments have scanned a single-pixel detector through the field of view to …
In this paper it is shown that the key to understanding the ghost imaging mystery are the crossing symmetric photon reactions in the nonlinear media. Then, an intuitive mechanism for the description of the ghost imaging in terms of the quantum mirror (QM) is presented. Moreover, we prove that the ghost imaging laws depend only on the energy-momentum conservation and not on the photons entanglement.
Monte Carlo Framework for Physics-Based Design and Optimization of X-Ray Compressive Ghost Imaging Systems
Physics Department and Institute of Nanotechnology, Bar-Ilan University（巴伊兰大学物理系与纳米技术研究所）；Radiation Safety Department, Soreq Nuclear Research Center（索雷克核研究中心辐射安全部）
Shanghai University（上海大学）；Inner Mongolia University of Technology（内蒙古工业大学）；KACST（沙特阿拉伯国王科学技术大学）；Institute of Quantum Technologies and Advanced Computing, KACST（沙特阿拉伯国王科学技术大学量子技术与先进计算研究所）
Vienna Center for Quantum Science and Technology, Atominstitut, TU Wien（维也纳量子科学中心，原子研究所，维也纳工业大学）；University Service Centre for Transmission Electron Microscopy, TU Wien（透射电子显微镜大学服务中心，维也纳工业大学）；Institute of Production Engineering and Photonic Technologies, TU Wien（生产工程与光子技术研究所，维也纳工业大学）
We investigate the effect of turbulence on quantum ghost imaging. We use entangled photons and demonstrate that for a novel experimental configuration the effect of turbulence can be greatly diminished. By decoupling the entangled photon source from the ghost imaging central image plane, we are able to dramatically increase the ghost image quality. When imaging a test pattern through turbulence, this method increased the imaged pattern visibility from V = 0.14 +/- 0.04 to V = 0.29 +/- 0.04.
3D printing allows rapid fabrication of complex objects from digital designs. One 3D-printing process, direct laser writing, polymerises a light-sensitive material by steering a focused laser beam through the shape of the object to be created. The highest-resolution direct laser writing systems use a femtosecond laser to effect two-photon polymerisation. The focal (polymerisation) point is steered over the shape of the desired object with mechanised stages or galvanometer-controlled mirrors. Here we report a new high-resolution direct laser writing system that employs a resonant mirror scanner…
We present a wide-field homodyne imaging system capable of recovering intensity and phase images of an object from a single camera frame at an illumination intensity significantly below the noise floor of the camera. By interfering a weak imaging signal with a much brighter reference beam we are able to image objects in the short-wave infrared down to signal intensity of $\sim$$1.1$ photons per pixel per frame incident on the sensor despite the camera having a noise floor of $\sim$$200$ photons per pixel. At this illumination level we operate under the conditions of a reference beam to probe b…
Traditional ghost imaging experiments exploit position correlations between correlated states of light. These correlations occur directly in spontaneous parametric down-conversion (SPDC), and in such a scenario, the two-photon state used for ghost imaging is symmetric. Here we perform ghost imaging using an anti-symmetric state, engineering the two-photon state symmetry by means of Hong-Ou-Mandel interference. We use both symmetric and anti-symmetric states and show that the ghost imaging setup configuration results in object-image rotations depending on the state selected. Further, the object…
Ghost imaging is an unconventional optical imaging technique that reconstructs the shape of an object combining the measurement of two signals: one that interacted with the object, but without any spatial information, the other containing spatial information, but that never interacted with the object. Ghost imaging is a very flexible technique, that has been generalized to the single-photon regime, to the time domain, to infrared and terahertz frequencies, and many more conditions. Here we demonstrate that ghost imaging can be performed without ever knowing the patterns illuminating the object…
Certification of nonlocality of quantum mechanics is an important fundamental test that typically requires prolonged data collection and is only revealed in an in-depth analysis. These features are often particularly exposed in hybrid systems, such as interfaces between light and atomic ensembles. Certification of entanglement from images acquired with single-photon camera can mitigate this issue by exploiting multiplexed photon generation. Here we demonstrate this feature in a quantum memory (QM) operating in a real-time feedback mode. Through spatially-multimode spin-wave storage the QM enab…
A recently introduced two-channel confocal microscope with correlated detection promises up to 50% improvement in transverse spatial resolution [Simon, Sergienko, Optics Express {\bf 18}, 9765 (2010)] via the use of photon correlations. Here we achieve similar results in a different manner, introducing a triple-confocal correlated microscope which exploits the correlations present in optical parametric amplifiers. It is based on tight focusing of pump radiation onto a thin sample positioned in front of a nonlinear crystal, followed by coincidence detection of signal and idler photons, each foc…
We develop a concept of metasurface-assisted ghost imaging for non-local discrimination between a set of polarization objects. The specially designed metasurfaces are incorporated in the imaging system to perform parallel state transformations in general elliptical bases of quantum-entangled or classically-correlated photons. Then, only four or fewer correlation measurements between multiple metasurface outputs and a simple polarization-insensitive bucket detector after the object can allow for the identification of fully or partially transparent polarization elements and their arbitrary orien…
Ghost imaging with thermal fermions is calculated based on two-particle interference in Feynman's path integral theory. It is found that ghost imaging with thermal fermions can be simulated by ghost imaging with thermal bosons and classical particles. Photons in pseudothermal light are employed to experimentally study fermionic ghost imaging. Ghost imaging with thermal bosons and fermions is discussed based on the point-to-point (spot) correlation between the object and image planes. The employed method offers an efficient guidance for future ghost imaging with real thermal fermions, which may…
Turbulence-free images cannot be produced by conventional computational ghost imaging because calculated light is not affected by the same atmospheric turbulence as real light. In this article, we first addressed this issue by measuring the photon number fluctuation autocorrelation of the signals generated by a conventional computational ghost imaging device. Our results illustrate how conventional computational ghost imaging without structural changes can be used to produce turbulence-free images.
An integrated microscope that combines different optical techniques for simultaneous imaging is demonstrated. The microscope enables spectral-domain optical coherence microscopy based on optical backscatter, and multi-photon microscopy for the detection of two-photon fluorescence and second harmonic generation signals. The unique configuration of this integrated microscope allows for the simultaneous acquisition of both anatomical (structural) and functional imaging information with particular emphasis for applications in the fields of tissue engineering and cell biology. In addition, the cont…
Classical ghost imaging is a computational imaging technique that employs patterned illumination. It is very similar in concept to the single-pixel camera in that an image may be reconstructed from a set of measurements even though all imaging quanta that pass through that sample are never recorded with a position resolving detector. The method was first conceived and applied for visible-wavelength photons and was subsequently translated to other probes such as x rays, atomic beams, electrons and neutrons. In the context of ghost imaging using penetrating probes that enable transmission measur…
The X-ray free electron lasers (XFEL) can enable diffractive structural determination of protein crystals or single molecules that are too radiation-sensitive for conventional X-ray analysis. However the electronic form factor could have been modified during the ultrashort X-ray pulse due to photoionization and electron cascade caused by the intense X-ray pulse. For general X-ray imaging techniques, to minimize radiation damage effect is of major concern to ensure faithful reconstruction of the structure. Here we show that a radiation-damage-free diffraction can be achieved with an atomic spat…
We show that, when the integration time of the single photon detectors is longer than the correlation time of the biphoton, the attainable spatial resolution in ghost imaging with entangled signal idler pairs generated in type II spontaneous parametric down conversion is limited by the angular spread of single-frequency-signal idler pairs. If, however, the detector integration time is shorter than the biphoton correlation time, the transverse k-vectors of different spectral components combine coherently in the image, improving the spatial resolution.
High visibility temporal ghost imaging with classical light is possible when superbunching pseudothermal light is employed. In the numerical simulation, the visibility of temporal ghost imaging with pseudothermal light equaling ($4.7\pm 0.2$)\% can be increased to ($75\pm 8$)\% in the same scheme with superbunching pseudothermal light. The reasons for the difference in visibility and quality of the retrieved images in different situations are discussed in detail. It is concluded that high visibility and high quality temporal ghost image can be obtained by collecting large enough number of data…
Hyperspectral imaging (HSI) has a wide range of applications from environmental monitoring to biotechnology. Current snapshot HSI techniques all require a trade-off between spatial and spectral resolution and are thus unable to achieve high resolutions in both simultaneously. Additionally, the techniques are resource inefficient with most of the photons lost through spectral filtering. Here, we demonstrate a snapshot HSI technique utilizing the strong spectro-temporal correlations inherent in entangled photons using a modified quantum ghost spectroscopy system, where the target is directly ima…
Samples for single-emitter spectroscopy are usually prepared by spin-coating a dilute solution of emitters on a microscope cover slip of silicate based glass (such as quartz). Here, we show that both borosilicate glass and quartz contain intrinsic defect colour centres that fluoresce when excited at 532 nm. In a microscope image the defect emission is indistinguishable from spin-coated emitters. The emission spectrum is characterised by multiple peaks, most likely due to coupling to a silica vibration with an energy of 160-180 meV. The defects are single-photon emitters, do not blink, and have…
Frequency correlations are a versatile and powerful tool which can be exploited to perform spectral analysis of objects whose direct measurement might be unfeasible. This is achieved through a so-called ghost spectrometer, that can be implemented with quantum and classical resources alike. While there are some known advantages associated to either choice, an analysis of their metrological capabilities has not yet been performed. Here we report on the metrological comparison between a quantum and a classical ghost spectrometer. We perform the estimation of the transmittivity of a bandpass filte…
Ghost imaging is a quantum optics technique that uses correlations between two beams to reconstruct an image in one beam from photons that do not interact with the object being imaged. While pairwise (second order) correlations are usually used to create the image, higher order correlations can be utilized to improve the performance of ghost imaging. In this paper, we demonstrate higher order atomic ghost imaging, using entangled ultracold metastable helium atoms from an s-wave collision halo. We construct higher order ghost images up to 5th order and show that using higher order correlations …
The concept of quantum entanglement and hyper-entanglement, lying at the heart of quantum information science and technologies, is physically counter-intuitive and mathematically elusive. We design a polarization-encoded ghost imaging system based on the frame of Hardy nonlocality paradox to visualize the evidence of quantum hyper-entanglement by capturing purely nonlocal photonic events. In two-photon polarization-spatial-mode hyper-entangled state, spatial entanglement con-veys the ghost images while polarization entanglement encodes the imaging channels. Then whether imaging the single ghos…
It is shown that the use of phase conjugation in one arm of a correlated two-photon imaging apparatus allows undistorted ghost imaging through a region with randomly-varying phase shifts. The images are formed from correlated pairs of photons in such a way that turbulence-induced phase shifts gained by the photons during passage through the medium cancel pairwise.
In this work, we propose a structured illumination (SI) method based on a two-photon excitation (TPE) scanning laser beam. Advantages of TPE methods include optical sectioning, low photo-toxicity, and robustness in the face of sample induced scattering. We designed a novel multi-spot point spread function (PSF) for a fast, two-photon scanning SIM microscope. Our multi-spot PSF is generated with a phase retrieval algorithm. We show how to obtain the phase distribution and then simulate the effect of this distribution on a spatial light modulator (SLM), which produces the multi-spot PSF in the o…
Control of light through a microscope objective with a high numerical aperture is a common requirement in applications such as optogenetics, adaptive optics, or laser processing. Light propagation, including polarization effects, can be described under these conditions using the Debye-Wolf diffraction integral. Here, we take advantage of differentiable optimization and machine learning for efficiently optimizing the Debye-Wolf integral for such applications. For light shaping we show that this optimization approach is suitable for engineering arbitrary three-dimensional point spread functions …
Two-Photon Laser-Scanning Microscopy is a powerful tool for exploring biological structure and function because of its ability to optically section through a sample with a tight focus. While it is possible to obtain 3D image stacks by moving a stage, this perframe imaging process is time consuming. Here, we present a method for an easy to implement and inexpensive modification of an existing two-photon microscope to rapidly image in 3D using an electrically tunable lens to create a tessellating scan pattern which repeats with the volume rate. Using appropriate interpolating algorithms, the vol…
Quantum Ghost Imaging (QGI) is an intriguing imaging protocol that exploits photon-pair correlations stemming from spontaneous parametric down-conversion (SPDC). QGI retrieves images from two-path joint measurements, where single-path detection does not allow to reconstruct the target image. This technique, has been so far limited in terms of acquisition speed either by raster scanning, or by the slow electronics of intensified cameras. Here we report on a fast QGI implementation exploiting a SPAD array detector for the spatially resolving path, enabling the acquisition of a ghost image in und…
