We propose an algorithm for electrocardiogram (ECG) segmentation using a UNet-like full-convolutional neural network. The algorithm receives an arbitrary sampling rate ECG signal as an input, and gives a list of onsets and offsets of P and T waves and QRS complexes as output. Our method of segmentation differs from others in speed, a small number of parameters and a good generalization: it is adaptive to different sampling rates and it is generalized to various types of ECG monitors. The proposed approach is superior to other state-of-the-art segmentation methods in terms of quality. In particular, F1-measures for detection of onsets and offsets of P and T waves and for QRS-complexes are at least 97.8%, 99.5%, and 99.9%, respectively.
Department of Control Theory（控制理论系）；Nizhny Novgorod State University（下诺夫哥罗德州立大学）
In this study we examined the question of how error correction occurs in an ensemble of deep convolutional networks, trained for an important applied problem: segmentation of Electrocardiograms(ECG). We also explore the possibility of using the information about ensemble errors to evaluate a quality of data representation, built by the network. This possibility arises from the effect of distillation of outliers, which was demonstarted for the ensemble, described in this paper.
Electrocardiogram (ECG) signal is the most commonly used non-invasive tool in the assessment of cardiovascular diseases. Segmentation of the ECG signal to locate its constitutive waves, in particular the R-peaks, is a key step in ECG processing and analysis. Over the years, several segmentation and QRS complex detection algorithms have been proposed with different features; however, their performance highly depends on applying preprocessing steps which makes them unreliable in real-time data analysis of ambulatory care settings and remote monitoring systems, where the collected data is highly …
Objectives: With the technological advancements in the field of tele-health monitoring, it is now possible to gather huge amounts of electro-physiological signals such as electrocardiogram (ECG). It is therefore necessary to develop models/algorithms that are capable of analysing these massive amounts of data in real-time. This paper proposes a deep learning model for real-time segmentation of heartbeats. Methods: The proposed algorithm, named as the DENS-ECG algorithm, combines convolutional neural network (CNN) and long short-term memory (LSTM) model to detect onset, peak, and offset of diff…
Hangzhou Dianzi University（杭州电子科技大学）；University of Science and Technology of China（中国科学技术大学）
Early recognition of abnormal rhythms in ECG signals is crucial for monitoring and diagnosing patients' cardiac conditions, increasing the success rate of the treatment. Classifying abnormal rhythms into exact categories is very challenging due to the broad taxonomy of rhythms, noises and lack of large-scale real-world annotated data. Different from previous methods that utilize hand-crafted features or learn features from the original signal domain, we propose a novel ECG classification method by learning deep time-frequency representation and progressive decision fusion at different temporal…
The electrocardiogram (ECG) follows a characteristic shape, which has led to the development of several mathematical models for extracting clinically important information. Our main objective is to resolve limitations of previous approaches, that means to simultaneously cope with various noise sources, perform exact beat segmentation, and to retain diagnostically important morphological information. Methods: We therefore propose a model that is based on Hermite and sigmoid functions combined with piecewise polynomial interpolation for exact segmentation and low-dimensional representation of in…
Universitat Pompeu Fabra（庞培法布拉大学）；Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN)（生物工程、生物材料与纳米医学生物医学研究网络中心（CIBER-BBN））；Aragón Institute of Engineering Research（阿拉贡工程研究所）；University of Zaragoza（萨拉戈萨大学）
Electrocardiogram (ECG) detection and delineation are key steps for numerous tasks in clinical practice, as ECG is the most performed non-invasive test for assessing cardiac condition. State-of-the-art algorithms employ digital signal processing (DSP), which require laborious rule adaptation to new morphologies. In contrast, deep learning (DL) algorithms, especially for classification, are gaining weight in academic and industrial settings. However, the lack of model explainability and small databases hinder their applicability. We demonstrate DL can be successfully applied to low interpretati…
Deep learning based ECG segmentation for delineation of diverse arrhythmias
Seoul National University（首尔大学）；Asan Medical Center, University of Ulsan College of Medicine（蔚山大学医学院附属峨山医院）；Pusan National University Hospital, Pusan National University School of Medicine（釜山大学医学院附属釜山国立大学医院）；AI Institute, Seoul National University（首尔大学人工智能研究院）；Seoul National University Hospital（首尔大学医院）；Medifarmsoft Co., Ltd.（Medifarmsoft有限公司）
本文提出一种类 U-Net 的心电图分割模型及后处理算法，用于在多种心律失常条件下准确 delineation P、QRS 和 T 波，并针对标准基准中代表性不足的心律失常提出改进策略。
In this article, we propose a novel ECG classification framework for atrial fibrillation (AF) detection using spectro-temporal representation (i.e., time varying spectrum) and deep convolutional networks. In the first step we use a Bayesian spectro-temporal representation based on the estimation of time-varying coefficients of Fourier series using Kalman filter and smoother. Next, we derive an alternative model based on a stochastic oscillator differential equation to accelerate the estimation of the spectro-temporal representation in lengthy signals. Finally, after comparative evaluations of …
Technion - Israel Institute of Technology（以色列理工学院）；Google Research（谷歌研究院）
Generating training examples for supervised tasks is a long sought after goal in AI. We study the problem of heart signal electrocardiogram (ECG) synthesis for improved heartbeat classification. ECG synthesis is challenging: the generation of training examples for such biological-physiological systems is not straightforward, due to their dynamic nature in which the various parts of the system interact in complex ways. However, an understanding of these dynamics has been developed for years in the form of mathematical process simulators. We study how to incorporate this knowledge into the gener…
School of Electrical and Electronics Engineering（电气与电子工程学院）；University of Manchester（曼彻斯特大学）
Effective and powerful methods for denoising real electrocardiogram (ECG) signals are important for wearable sensors and devices. Deep Learning (DL) models have been used extensively in image processing and other domains with great success but only very recently have been used in processing ECG signals. This paper presents several DL models namely Convolutional Neural Networks (CNNs), Long Short-Term Memory (LSTM), Restricted Boltzmann Machine (RBM) together with the more conventional filtering methods (low pass filtering, high pass filtering, Notch filtering) and the standard wavelet-based te…
IBM Research - Africa（IBM非洲研究院）；University of Oxford（牛津大学）；Guangdong Cardiovascular Institute（广东省心血管病研究所）
Myocardial Infarction (MI) has the highest mortality of all cardiovascular diseases (CVDs). Detection of MI and information regarding its occurrence-time in particular, would enable timely interventions that may improve patient outcomes, thereby reducing the global rise in CVD deaths. Electrocardiogram (ECG) recordings are currently used to screen MI patients. However, manual inspection of ECGs is time-consuming and prone to subjective bias. Machine learning methods have been adopted for automated ECG diagnosis, but most approaches require extraction of ECG beats or consider leads independentl…
School of Computer Science and Technology, Harbin Institute of Technology (HIT)（哈尔滨工业大学计算机科学与技术学院）；School of Physics and Astronomy, The University of Manchester（曼彻斯特大学物理与天文学院）；SPACEnter Space Science and Technology Institute（SPACEnter空间科学与技术研究院）；Northeastern University（东北大学）；Beijing Electric Power Hospital（北京电力医院）
Heart disease is one of the most common diseases causing morbidity and mortality. Electrocardiogram (ECG) has been widely used for diagnosing heart diseases for its simplicity and non-invasive property. Automatic ECG analyzing technologies are expected to reduce human working load and increase diagnostic efficacy. However, there are still some challenges to be addressed for achieving this goal. In this study, we develop an algorithm to identify multiple abnormalities from 12-lead ECG recordings. In the algorithm pipeline, several preprocessing methods are firstly applied on the ECG data for de…
The classification of electrocardiogram (ECG) signals, which takes much time and suffers from a high rate of misjudgment, is recognized as an extremely challenging task for cardiologists. The major difficulty of the ECG signals classification is caused by the long-term sequence dependencies. Most existing approaches for ECG signal classification use Recurrent Neural Network models, e.g., LSTM and GRU, which are unable to extract accurate features for such long sequences. Other approaches utilize 1-Dimensional Convolutional Neural Network (CNN), such as ResNet or its variant, and they can not m…
The complexity of the patterns associated with Atrial Fibrillation (AF) and the high level of noise affecting these patterns have significantly limited the current signal processing and shallow machine learning approaches to get accurate AF detection results. Deep neural networks have shown to be very powerful to learn the non-linear patterns in the data. While a deep learning approach attempts to learn complex pattern related to the presence of AF in the ECG, they can benefit from knowing which parts of the signal is more important to focus during learning. In this paper, we introduce a two-c…
Universidade Federal de Minas Gerais（米纳斯吉拉斯联邦大学）；Uppsala University（乌普萨拉大学）；Telehealth Center from Hospital das Clínicas da Universidade Federal de Minas Gerais（米纳斯吉拉斯联邦大学医院临床中心远程医疗中心）；Hospital das Clínicas da Universidade Federal de Minas Gerais（米纳斯吉拉斯联邦大学医院临床中心（注：此处原文本中“Telehealth Center from Hospital das Clínicas da Universidade Federal de Minas Gerais”中的“Hospital das Clínicas da Universidade Federal de Minas Gerais”是更基础的机构，按要求提取到大学级别或包含的独立机构，此处直接提取该医院作为机构名））
We present a model for predicting electrocardiogram (ECG) abnormalities in short-duration 12-lead ECG signals which outperformed medical doctors on the 4th year of their cardiology residency. Such exams can provide a full evaluation of heart activity and have not been studied in previous end-to-end machine learning papers. Using the database of a large telehealth network, we built a novel dataset with more than 2 million ECG tracings, orders of magnitude larger than those used in previous studies. Moreover, our dataset is more realistic, as it consist of 12-lead ECGs recorded during standard i…
The Ohio State University（俄亥俄州立大学）；Wuhan University of Technology（武汉理工大学）
Electrocardiogram (ECG) is a widely used reliable, non-invasive approach for cardiovascular disease diagnosis. With the rapid growth of ECG examinations and the insufficiency of cardiologists, accurate and automatic diagnosis of ECG signals has become a hot research topic. Deep learning methods have demonstrated promising results in predictive healthcare tasks. In this paper, we developed a deep neural network for multi-label classification of cardiac arrhythmias in 12-lead ECG recordings. Experiments on a public 12-lead ECG dataset showed the effectiveness of our method. The proposed model ac…
University of Alberta（阿尔伯塔大学）；Canadian VIGOUR Centre（加拿大VIGOUR中心）；Alberta Machine Intelligence Institute（阿尔伯塔机器智能研究所）
Electrocardiogram (ECG) abnormalities are linked to cardiovascular diseases, but may also occur in other non-cardiovascular conditions such as mental, neurological, metabolic and infectious conditions. However, most of the recent success of deep learning (DL) based diagnostic predictions in selected patient cohorts have been limited to a small set of cardiac diseases. In this study, we use a population-based dataset of >250,000 patients with >1000 medical conditions and >2 million ECGs to identify a wide range of diseases that could be accurately diagnosed from the patient's first in-hospital …
Deep Neural Networks Generalization and Fine-Tuning for 12-lead ECG Classification
Ivannikov Institute for System Programming of the Russian Academy of Sciences（俄罗斯科学院伊万尼科夫系统编程研究所）；Russian-Armenian University（俄罗斯-亚美尼亚大学）；Novgorod State University（诺夫哥罗德国立大学）
The University of Tennessee（田纳西大学）；University of Oklahoma Health Sciences Center（俄克拉荷马大学健康科学中心）
Cardiac disease is the leading cause of death in the US. Accurate heart disease detection is of critical importance for timely medical treatment to save patients' lives. Routine use of electrocardiogram (ECG) is the most common method for physicians to assess the electrical activities of the heart and detect possible abnormal cardiac conditions. Fully utilizing the ECG data for reliable heart disease detection depends on developing effective analytical models. In this paper, we propose a two-level hierarchical deep learning framework with Generative Adversarial Network (GAN) for automatic diag…
University of Arizona（亚利桑那大学）；Rowan University（罗文大学）；Bio5 Institute（Bio5研究所）
Objective: Electrocardiogram (ECG) signals commonly suffer noise interference, such as baseline wander. High-quality and high-fidelity reconstruction of the ECG signals is of great significance to diagnosing cardiovascular diseases. Therefore, this paper proposes a novel ECG baseline wander and noise removal technology. Methods: We extended the diffusion model in a conditional manner that was specific to the ECG signals, namely the Deep Score-Based Diffusion model for Electrocardiogram baseline wander and noise removal (DeScoD-ECG). Moreover, we deployed a multi-shots averaging strategy that i…
Electrocardiogram (ECG) is the most crucial monitoring modality to diagnose cardiovascular events. Precise and automatic detection of abnormal ECG patterns is beneficial to both physicians and patients. In the automatic detection of abnormal ECG patterns, deep neural networks (DNNs) have shown significant achievements. However, DNNs require large amount of labeled data, which are often expensive to obtain. On the other hand, recent research have shown by randomly combining data augmentations can improve image classification accuracy. Thus, in this work we explore data augmentation suitable for…
Atrial fibrillation (AF) is the most prevalent heart arrhythmia. AF manifests on the electrocardiogram (ECG) though irregular beat-to-beat time interval variation, the absence of P-wave and the presence of fibrillatory waves (f-wave). We hypothesize that a deep learning (DL) approach trained on the raw ECG will enable robust detection of AF events and the estimation of the AF burden (AFB). We further hypothesize that the performance reached leveraging the raw ECG will be superior to previously developed methods using the beat-to-beat interval variation time series. Consequently, we develop a n…
Universidade Federal de Minas Gerais（米纳斯吉拉斯联邦大学）；Uppsala University（乌普萨拉大学）；Hospital das Clínicas da Universidade Federal de Minas Gerais（米纳斯吉拉斯联邦大学临床医院）；Glasgow University（格拉斯哥大学）
The role of automatic electrocardiogram (ECG) analysis in clinical practice is limited by the accuracy of existing models. Deep Neural Networks (DNNs) are models composed of stacked transformations that learn tasks by examples. This technology has recently achieved striking success in a variety of task and there are great expectations on how it might improve clinical practice. Here we present a DNN model trained in a dataset with more than 2 million labeled exams analyzed by the Telehealth Network of Minas Gerais and collected under the scope of the CODE (Clinical Outcomes in Digital Electroca…
Due to the multiple imperfections during the signal acquisition, Electrocardiogram (ECG) datasets are typically contaminated with numerous types of noise, like salt and pepper and baseline drift. These datasets may contain different recordings with various types of noise [1] and thus, denoising may not be the easiest task. Furthermore, usually, the number of labeled bio-signals is very limited for a proper classification task.
Fraunhofer Institute for Integrated Circuits IIS（弗劳恩霍夫集成电路研究所）；Friedrich-Alexander University Erlangen-Nürnberg（埃尔朗根-纽伦堡弗里德里希-亚历山大大学）；University of Leeds（利兹大学）
Cardiovascular diseases are the most common cause of mortality worldwide. Detection of atrial fibrillation (AF) in the asymptomatic stage can help prevent strokes. It also improves clinical decision making through the delivery of suitable treatment such as, anticoagulant therapy, in a timely manner. The clinical significance of such early detection of AF in electrocardiogram (ECG) signals has inspired numerous studies in recent years, of which many aim to solve this task by leveraging machine learning algorithms. ECG datasets containing AF samples, however, usually suffer from severe class imb…
Monitoring medical data, e.g., Electrocardiogram (ECG) signals, is a common application of Internet of Things (IoT) devices. Compression methods are often applied on the massive amounts of sensor data generated prior to sending it to the Cloud to reduce the storage and delivery costs. A lossy compression provides high compression gain (CG), but may reduce the performance of an ECG application (downstream task) due to information loss. Previous works on ECG monitoring focus either on optimizing the signal reconstruction or the task's performance. Instead, we advocate a self-adapting lossy compr…
Explaining Deep Learning for ECG Analysis: Building Blocks for Auditing and Knowledge Discovery
Fraunhofer Heinrich Hertz Institute（弗劳恩霍夫海因里希·赫兹研究所）；Physikalisch-Technische Bundesanstalt（德国联邦物理技术研究院）；Charité Universitätsmedizin Berlin（柏林夏里特医学院）；Carl von Ossietzky Universität Oldenburg（奥尔登堡卡尔·冯·奥西茨基大学）
Healthcare Technology and Innovation Center (HTIC), Indian Institute of Technology (IIT-M)（印度理工学院（马德拉斯）医疗技术与创新中心）；Indian Institute of Technology, Madras (IITM)（印度理工学院马德拉斯分校）
Automatic detection of R-peaks in an Electrocardiogram signal is crucial in a multitude of applications including Heart Rate Variability (HRV) analysis and Cardio Vascular Disease(CVD) diagnosis. Although there have been numerous approaches that have successfully addressed the problem, there has been a notable dip in the performance of these existing detectors on ECG episodes that contain noise and HRV Irregulates. On the other hand, Deep Learning(DL) based methods have shown to be adept at modelling data that contain noise. In image to image translation, Unet is the fundamental block in many …
Electrocardiogram (ECG) signals are beneficial in diagnosing cardiovascular diseases, which are one of the leading causes of death. However, they are often contaminated by noise artifacts and affect the automatic and manual diagnosis process. Automatic deep learning-based examination of ECG signals can lead to inaccurate diagnosis, and manual analysis involves rejection of noisy ECG samples by clinicians, which might cost extra time. To address this limitation, we present a two-stage deep learning-based framework to automatically detect the noisy ECG samples. Through extensive experiments and …
ECGrecover: a Deep Learning Approach for Electrocardiogram Signal Completion
IRD（法国发展研究院）；Sorbonne Université（索邦大学）；University Paris-Saclay（巴黎-萨克雷大学）；INSERM（法国国家健康与医学研究院）；Pitié-Salpêtrière University Hospital（皮蒂-萨尔皮特里大学医院）；Vanderbilt University Medical Center（范德堡大学医学中心）；AP-HP（巴黎公共医疗集团）；Hôpital Pitié-Salpêtrière（皮蒂-萨尔皮特里医院）
Currently, the telehealth monitoring field has gained huge attention due to its noteworthy use in day-to-day life. This advancement has led to an increase in the data collection of electrophysiological signals. Due to this advancement, electrocardiogram (ECG) signal monitoring has become a leading task in the medical field. ECG plays an important role in the medical field by analysing cardiac physiology and abnormalities. However, these signals are affected due to numerous varieties of noises, such as electrode motion, baseline wander and white noise etc., which affects the diagnosis accuracy.…
The number of IoT devices in healthcare is expected to rise sharply due to increased demand since the COVID-19 pandemic. Deep learning and IoT devices are being employed to monitor body vitals and automate anomaly detection in clinical and non-clinical settings. Most of the current technology requires the transmission of raw data to a remote server, which is not efficient for resource-constrained IoT devices and embedded systems. Additionally, it is challenging to develop a machine learning model for ECG classification due to the lack of an extensive open public database. To an extent, to over…
Zhejiang University（浙江大学）；The First Affiliated Hospital of University of Science and Technology of China（中国科学技术大学附属第一医院）；HeartVoice Medical Technology（心声医疗科技）；University of Science and Technology of China（中国科学技术大学）；Peking University（北京大学）
With the development of deep learning-based methods, automated classification of electrocardiograms (ECGs) has recently gained much attention. Although the effectiveness of deep neural networks has been encouraging, the lack of information given by the outputs restricts clinicians' reexamination. If the uncertainty estimation comes along with the classification results, cardiologists can pay more attention to "uncertain" cases. Our study aims to classify ECGs with rejection based on data uncertainty and model uncertainty. We perform experiments on a real-world 12-lead ECG dataset. First, we es…
Healthcare Technology Innovation Centre Indian Institute of Technology Madras（印度理工学院马德拉斯分校医疗技术创新中心）；Department of Electrical Engineering Indian Institute of Technology Madras（印度理工学院马德拉斯分校电气工程系）
Continuous monitoring of cardiac health under free living condition is crucial to provide effective care for patients undergoing post operative recovery and individuals with high cardiac risk like the elderly. Capacitive Electrocardiogram (cECG) is one such technology which allows comfortable and long term monitoring through its ability to measure biopotential in conditions without having skin contact. cECG monitoring can be done using many household objects like chairs, beds and even car seats allowing for seamless monitoring of individuals. This method is unfortunately highly susceptible to …
China Academy of Electronics and Information Technology（中国电子科技集团公司电子科学研究院）
The traditional method of diagnosing heart disease on ECG signal is artificial observation. Some have tried to combine expertise and signal processing to classify ECG signal by heart disease type. However, the currency is not so sufficient that it can be used in medical applications. We develop an algorithm that combines signal processing and deep learning to classify ECG signals into Normal AF other rhythm and noise, which help us solve this problem. It is demonstrated that we can obtain the time-frequency diagram of ECG signal by wavelet transform, and use DNN to classify the time-frequency …
Personality Trait Recognition using ECG Spectrograms and Deep Learning
University of Engineering and Technology, Taxila（塔克西拉工程技术大学）；Sheikh Zayed Institute for Pediatric Surgical Innovation（谢赫·扎耶德儿科外科创新研究所）；Children’s National Hospital（儿童国家医院）；School of Medicine and Health Sciences, George Washington University（乔治·华盛顿大学医学与健康科学学院）
HeartVoice Medical Technology（心音医疗科技）；University of Science and Technology of China（中国科学技术大学）
Electrocardiogram (ECG) is one of the most convenient and non-invasive tools for monitoring peoples' heart condition, which can use for diagnosing a wide range of heart diseases, including Cardiac Arrhythmia, Acute Coronary Syndrome, et al. However, traditional ECG disease detection models show substantial rates of misdiagnosis due to the limitations of the abilities of extracted features. Recent deep learning methods have shown significant advantages, but they do not provide publicly available services for those who have no training data or computational resources. In this paper, we demonstra…
Cardiovascular disease has become one of the most significant threats endangering human life and health. Recently, Electrocardiogram (ECG) monitoring has been transformed into remote cardiac monitoring by Holter surveillance. However, the widely used Holter can bring a great deal of discomfort and inconvenience to the individuals who carry them. We developed a new wireless ECG patch in this work and applied a deep learning framework based on the Convolutional Neural Network (CNN) and Long Short-term Memory (LSTM) models. However, we find that the models using the existing techniques are not ab…
