Asim Smailagic, Pedro Costa, Alex Gaudio, Kartik Khandelwal, Mostafa Mirshekari, Jonathon Fagert, Devesh Walawalkar, Susu Xu, Adrian Galdran, Pei Zhang, Aurélio… 展开作者
Asim Smailagic, Pedro Costa, Alex Gaudio, Kartik Khandelwal, Mostafa Mirshekari, Jonathon Fagert, Devesh Walawalkar, Susu Xu, Adrian Galdran, Pei Zhang, Aurélio Campilho, Hae Young Noh
Active Learning methods create an optimized labeled training set from unlabeled data. We introduce a novel Online Active Deep Learning method for Medical Image Analysis. We extend our MedAL active learning framework to present new results in this paper. Our novel sampling method queries the unlabeled examples that maximize the average distance to all training set examples. Our online method enhances performance of its underlying baseline deep network. These novelties contribute significant performance improvements, including improving the model's underlying deep network accuracy by 6.30%, using only 25% of the labeled dataset to achieve baseline accuracy, reducing backpropagated images during training by as much as 67%, and demonstrating robustness to class imbalance in binary and multi-class tasks.
Deep learning models have been successfully used in medical image analysis problems but they require a large amount of labeled images to obtain good performance.Deep learning models have been successfully used in medical image analysis problems but they require a large amount of labeled images to obtain good performance. However, such large labeled datasets are costly to acquire. Active learning techniques can be used to minimize the number of required training labels while maximizing the model's performance.In this work, we propose a novel sampling method that queries the unlabeled examples t…
One of the biggest challenges that prohibit the use of many current NLP methods in clinical settings is the availability of public datasets. In this work, we present MeDAL, a large medical text dataset curated for abbreviation disambiguation, designed for natural language understanding pre-training in the medical domain. We pre-trained several models of common architectures on this dataset and empirically showed that such pre-training leads to improved performance and convergence speed when fine-tuning on downstream medical tasks.
In order to be able to use artificial intelligence (AI) in medicine without scepticism and to recognise and assess its growing potential, a basic understanding of this topic is necessary among current and future medical staff. Under the premise of "trust through understanding", we developed an innovative online course as a learning opportunity within the framework of the German KI Campus (AI campus) project, which is a self-guided course that teaches the basics of AI for the analysis of medical image data. The main goal is to provide a learning environment for a sufficient understanding of AI …
The Chinese University of Hong Kong（香港中文大学）；Department of Computer Science and Engineering, The Chinese University of Hong Kong（香港中文大学计算机科学与工程学系）；Guangdong Provincial Key Laboratory of Computer Vision and Virtual Reality Technology（广东省计算机视觉与虚拟现实技术重点实验室）；Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）
The success of deep convolutional neural networks is partially attributed to the massive amount of annotated training data. However, in practice, medical data annotations are usually expensive and time-consuming to be obtained. Considering multi-modality data with the same anatomic structures are widely available in clinic routine, in this paper, we aim to exploit the prior knowledge (e.g., shape priors) learned from one modality (aka., assistant modality) to improve the segmentation performance on another modality (aka., target modality) to make up annotation scarcity. To alleviate the learni…
Transformer has achieved impressive successes for various computer vision tasks. However, most of existing studies require to pretrain the Transformer backbone on a large-scale labeled dataset (e.g., ImageNet) for achieving satisfactory performance, which is usually unavailable for medical images. Additionally, due to the gap between medical and natural images, the improvement generated by the ImageNet pretrained weights significantly degrades while transferring the weights to medical image processing tasks. In this paper, we propose Bootstrap Own Latent of Transformer (BOLT), a self-supervise…
Segmentation is a key step in analyzing and processing medical images. Due to the low fault tolerance in medical imaging, manual segmentation remains the de facto standard in this domain. Besides, efforts to automate the segmentation process often rely on large amounts of manually labeled data. While existing software supporting manual segmentation is rich in features and delivers accurate results, the necessary time to set it up and get comfortable using it can pose a hurdle for the collection of large datasets. This work introduces a client/server based online environment, referred to as Stu…
MetaLR: Meta-tuning of Learning Rates for Transfer Learning in Medical Imaging
The Chinese University of Hong Kong (Shenzhen)（香港中文大学（深圳））；Shenzhen Research Institute of Big Data（深圳大数据研究院）；The Hong Kong University of Science and Technology (Guangzhou)（香港科技大学（广州））；Fudan University（复旦大学）；Johns Hopkins University（约翰斯·霍普金斯大学）
Neural networks often require large amounts of expert annotated data to train. When changes are made in the process of medical imaging, trained networks may not perform as well, and obtaining large amounts of expert annotations for each change in the imaging process can be time consuming and expensive. Online unsupervised learning is a method that has been proposed to deal with situations where there is a domain shift in incoming data, and a lack of annotations. The aim of this study is to see whether online unsupervised learning can help COVID-19 CT scan classification models adjust to slight…
Fueled by recent advances in machine learning, there has been tremendous progress in the field of semantic segmentation for the medical image computing community. However, developed algorithms are often optimized and validated by hand based on one task only. In combination with small datasets, interpreting the generalizability of the results is often difficult. The Medical Segmentation Decathlon challenge addresses this problem, and aims to facilitate development of generalizable 3D semantic segmentation algorithms that require no manual parametrization. Such an algorithm was developed and is …
Graz University of Technology（格拉茨工业大学）；Medical University of Graz（格拉茨医科大学）
We introduce a fully automatic system for cranial implant design, a common task in cranioplasty operations. The system is currently integrated in Studierfenster (http://studierfenster.tugraz.at/), an online, cloud-based medical image processing platform for medical imaging applications. Enhanced by deep learning algorithms, the system automatically restores the missing part of a skull (i.e., skull shape completion) and generates the desired implant by subtracting the defective skull from the completed skull. The generated implant can be downloaded in the STereoLithography (.stl) format directl…
The Chinese University of Hong Kong（香港中文大学）；Imsight Medical Technology Inc（视见医疗科技公司）
Deep neural networks (DNNs) have achieved great success in a wide variety of medical image analysis tasks. However, these achievements indispensably rely on the accurately-annotated datasets. If with the noisy-labeled images, the training procedure will immediately encounter difficulties, leading to a suboptimal classifier. This problem is even more crucial in the medical field, given that the annotation quality requires great expertise. In this paper, we propose an effective iterative learning framework for noisy-labeled medical image classification, to combat the lacking of high quality anno…
University of Illinois, Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）；University of Michigan, Ann Arbor（密歇根大学安娜堡分校）
Techniques exploiting the sparsity of images in a transform domain have been effective for various applications in image and video processing. Transform learning methods involve cheap computations and have been demonstrated to perform well in applications such as image denoising and medical image reconstruction. Recently, we proposed methods for online learning of sparsifying transforms from streaming signals, which enjoy good convergence guarantees, and involve lower computational costs than online synthesis dictionary learning. In this work, we apply online transform learning to video denois…
Modern deep learning systems for medical image classification have demonstrated exceptional capabilities for distinguishing between image based medical categories. However, they are severely hindered by their ina-bility to explain the reasoning behind their decision making. This is partly due to the uninterpretable continuous latent representations of neural net-works. Emergent languages (EL) have recently been shown to enhance the capabilities of neural networks by equipping them with symbolic represen-tations in the framework of referential games. Symbolic representations are one of the corn…
MedDIFT: Multi-Scale Diffusion-Based Correspondence in 3D Medical Imaging
1 School of Computation, Information；Technology, Technical University of Munich 2 Institute of Machine Learning in Biomedical Imaging, Helmholtz Munich 3 Munich Center for Machine Learning (MCML) 4 Institute for Diagnostic；Interventional Radiology, Klinkum Rechts der Isar 5 School of Biomedical Engineering \& Imaging Sciences, King’s College London
Deep learning has demonstrated significant improvements in medical image segmentation using a sufficiently large amount of training data with manual labels. Acquiring well-representative labels requires expert knowledge and exhaustive labors. In this paper, we aim to boost the performance of semi-supervised learning for medical image segmentation with limited labels using a self-ensembling contrastive learning technique. To this end, we propose to train an encoder-decoder network at image-level with small amounts of labeled images, and more importantly, we learn latent representations directly…
BSDA: Bayesian Random Semantic Data Augmentation for Medical Image Classification
Chengdu Institute of Computer Application, Chinese Academy of Sciences（中国科学院成都计算机应用研究所）；School of Computer Science and Technology, University of Chinese Academy of Sciences（中国科学院大学计算机科学与技术学院）
Improving Segment Anything on the Fly: Auxiliary Online Learning and Adaptive Fusion for Medical Image Segmentation
School of Computer Science and Engineering, Nanjing University of Science and Technology（南京理工大学计算机科学与工程学院）；Digital Medical Research Center, School of Basic Medical Sciences, Fudan University（复旦大学基础医学院数字医学研究中心）；Shanghai Jiaotong University（上海交通大学）；the Chinese University of Hong Kong（香港中文大学）
University of Michigan（密歇根大学）；NYU Langone Health（纽约大学朗格尼医学中心）
Recent years have witnessed a significant increase in the online sharing of medical information, with videos representing a large fraction of such online sources. Previous studies have however shown that more than half of the health-related videos on platforms such as YouTube contain misleading information and biases. Hence, it is crucial to build computational tools that can help evaluate the quality of these videos so that users can obtain accurate information to help inform their decisions. In this study, we focus on the automatic detection of misinformation in YouTube videos. We select pro…
In medical diagnosis, physicians predict the state of a patient by checking measurements (features) obtained from a sequence of tests, e.g., blood test, urine test, followed by invasive tests. As tests are often costly, one would like to obtain only those features (tests) that can establish the presence or absence of the state conclusively. Another aspect of medical diagnosis is that we are often faced with unsupervised prediction tasks as the true state of the patients may not be known. Motivated by such medical diagnosis problems, we consider a {\it Cost-Sensitive Medical Diagnosis} (CSMD) p…
Shenzhen University（深圳大学）；The Chinese University of Hong Kong（香港中文大学）；University of Leeds（利兹大学）；Shenzhen RayShape Medical Technology Co., Ltd（深圳睿影医疗科技有限公司）
Deep segmentation models often face the failure risks when the testing image presents unseen distributions. Improving model robustness against these risks is crucial for the large-scale clinical application of deep models. In this study, inspired by human learning cycle, we propose a novel online reflective learning framework (RefSeg) to improve segmentation robustness. Based on the reflection-on-action conception, our RefSeg firstly drives the deep model to take action to obtain semantic segmentation. Then, RefSeg triggers the model to reflect itself. Because making deep models realize their …
Dalhousie University（达尔豪斯大学）；University of Ottawa（渥太华大学）；Technical University of Moldova（摩尔多瓦技术大学）
We propose the Echo-Chamber Effect assessment of an online forum. Sentiments perceived by the forum readers are at the core of the analysis; a complete message is the unit of the study. We build 14 models and apply those to represent discussions gathered from an online medical forum. We use four multi-class sentiment classification applications and two Machine Learning algorithms to evaluate prowess of the assessment models.
Telehealth helps to facilitate access to medical professionals by enabling remote medical services for the patients. These services have become gradually popular over the years with the advent of necessary technological infrastructure. The benefits of telehealth have been even more apparent since the beginning of the COVID-19 crisis, as people have become less inclined to visit doctors in person during the pandemic. In this paper, we focus on facilitating the chat sessions between a doctor and a patient. We note that the quality and efficiency of the chat experience can be critical as the dema…
Social media has been considered as a data source for tracking disease. However, most analyses are based on models that prioritize strong correlation with population-level disease rates over determining whether or not specific individual users are actually sick. Taking a different approach, we develop a novel system for social-media based disease detection at the individual level using a sample of professionally diagnosed individuals. Specifically, we develop a system for making an accurate influenza diagnosis based on an individual's publicly available Twitter data. We find that about half (1…
The medical domain is often subject to information overload. The digitization of healthcare, constant updates to online medical repositories, and increasing availability of biomedical datasets make it challenging to effectively analyze the data. This creates additional work for medical professionals who are heavily dependent on medical data to complete their research and consult their patients. This paper aims to show how different text highlighting techniques can capture relevant medical context. This would reduce the doctors' cognitive load and response time to patients by facilitating them …
Massachusetts General Hospital（麻省总医院）；Harvard Medical School（哈佛医学院）；Massachusetts Institute of Technology（麻省理工学院）；Univ. Lille（里尔大学）；Inserm（法国国家健康与医学研究院）；CHU Lille（里尔大学医院）
Image synthesis via Generative Adversarial Networks (GANs) of three-dimensional (3D) medical images has great potential that can be extended to many medical applications, such as, image enhancement and disease progression modeling. However, current GAN technologies for 3D medical image synthesis need to be significantly improved to be readily adapted to real-world medical problems. In this paper, we extend the state-of-the-art StyleGAN2 model, which natively works with two-dimensional images, to enable 3D image synthesis. In addition to the image synthesis, we investigate the controllability a…
The rate at which medical questions are asked online far exceeds the capacity of qualified people to answer them, and many of these questions are not unique. Identifying same-question pairs could enable questions to be answered more effectively. While many research efforts have focused on the problem of general question similarity for non-medical applications, these approaches do not generalize well to the medical domain, where medical expertise is often required to determine semantic similarity. In this paper, we show how a semi-supervised approach of pre-training a neural network on medical …
Nanjing University of Aeronautics and Astronautics（南京航空航天大学）
Deep neural networks are discovered to be non-robust when attacked by imperceptible adversarial examples, which is dangerous for it applied into medical diagnostic system that requires high reliability. However, the defense methods that have good effect in natural images may not be suitable for medical diagnostic tasks. The preprocessing methods (e.g., random resizing, compression) may lead to the loss of the small lesions feature in the medical image. Retraining the network on the augmented data set is also not practical for medical models that have already been deployed online. Accordingly, …
Graz University of Technology（格拉茨工业大学）；Medical University of Graz（格拉茨医科大学）；University Medicine Essen（埃森大学医学院）；German Cancer Consortium (DKTK)（德国癌症联盟（DKTK））
Deep learning (DL) has remarkably impacted several different scientific disciplines over the last few years. E.g., in image processing and analysis, DL algorithms were able to outperform other cutting-edge methods. Additionally, DL has delivered state-of-the-art results in tasks like autonomous driving, outclassing previous attempts. There are even instances where DL outperformed humans, for example with object recognition and gaming. DL is also showing vast potential in the medical domain. With the collection of large quantities of patient records and data, and a trend towards personalized tr…
University of Copenhagen（哥本哈根大学）；Rigshospitalet（哥本哈根大学国立医院）
Medical imaging plays a vital role in modern diagnostics and treatment. The temporal nature of disease or treatment progression often results in longitudinal data. Due to the cost and potential harm, acquiring large medical datasets necessary for deep learning can be difficult. Medical image synthesis could help mitigate this problem. However, until now, the availability of GANs capable of synthesizing longitudinal volumetric data has been limited. To address this, we use the recent advances in latent space-based image editing to propose a novel joint learning scheme to explicitly embed tempor…
Dalian University of Technology（大连理工大学）；Worcester Polytechnic Institute（伍斯特理工学院）；Indiana University（印第安纳大学）；Alibaba DAMO Academy（阿里巴巴达摩院）
Objective: Ubiquitous internet access is reshaping the way we live, but it is accompanied by unprecedented challenges in preventing chronic diseases that are usually planted by long exposure to unhealthy lifestyles. This paper proposes leveraging online shopping behaviors as a proxy for personal lifestyle choices to improve chronic disease prevention literacy, targeted for times when e-commerce user experience has been assimilated into most people's everyday lives. Methods: Longitudinal query logs and purchase records from 15 million online shoppers were accessed, constructing a broad spectrum…
People increasingly search online for answers to their medical questions but the rate at which medical questions are asked online significantly exceeds the capacity of qualified people to answer them. This leaves many questions unanswered or inadequately answered. Many of these questions are not unique, and reliable identification of similar questions would enable more efficient and effective question answering schema. COVID-19 has only exacerbated this problem. Almost every government agency and healthcare organization has tried to meet the informational need of users by building online FAQs,…
University of Texas at Austin（德克萨斯大学奥斯汀分校）；Snap Inc.（Snap公司）
Concept shift is a prevailing problem in natural tasks like medical image segmentation where samples usually come from different subpopulations with variant correlations between features and labels. One common type of concept shift in medical image segmentation is the "information imbalance" between label-sparse samples with few (if any) segmentation labels and label-dense samples with plentiful labeled pixels. Existing distributionally robust algorithms have focused on adaptively truncating/down-weighting the "less informative" (i.e., label-sparse in our context) samples. To exploit data feat…
Sparsity and low-rank models have been popular for reconstructing images and videos from limited or corrupted measurements. Dictionary or transform learning methods are useful in applications such as denoising, inpainting, and medical image reconstruction. This paper proposes a framework for online (or time-sequential) adaptive reconstruction of dynamic image sequences from linear (typically undersampled) measurements. We model the spatiotemporal patches of the underlying dynamic image sequence as sparse in a dictionary, and we simultaneously estimate the dictionary and the images sequentially…
Satbayev University（萨塔巴耶夫大学）；Assiut University（艾斯尤特大学）；International IT University（国际信息技术大学）
Artificial intelligence can now provide more solutions for different problems, especially in the medical field. One of those problems the lack of answers to any given medical/health-related question. The Internet is full of forums that allow people to ask some specific questions and get great answers for them. Nevertheless, browsing these questions in order to locate one similar to your own, also finding a satisfactory answer is a difficult and time-consuming task. This research will introduce a solution to this problem by automating the process of generating qualified answers to these questio…
