Myocardium segmentation of late gadolinium enhancement (LGE) Cardiac MR images is important for evaluation of infarction regions in clinical practice. The pathological myocardium in LGE images presents distinctive brightness and textures compared with the healthy tissues, making it much more challenging to be segment. Instead, the balanced-Steady State Free Precession (bSSFP) cine images show clearly boundaries and can be easily segmented. Given this fact, we propose a novel shape-transfer GAN for LGE images, which can 1) learn to generate realistic LGE images from bSSFP with the anatomical shape preserved, and 2) learn to segment the myocardium of LGE images from these generated images. It's worth to note that no segmentation label of the LGE images is used during this procedure. We test our model on dataset from the Multi-sequence Cardiac MR Segmentation Challenge. The results show that the proposed Shape-Transfer GAN can achieve accurate myocardium masks of LGE images.
TAI-GAN: A Temporally and Anatomically Informed Generative Adversarial Network for early-to-late frame conversion in dynamic cardiac PET inter-frame motion correction
Yale University（耶鲁大学）；IBM Research（IBM研究院）；Yale New Haven Hospital（耶鲁-纽黑文医院）；Yale School of Medicine（耶鲁医学院）
Existing conditional image synthesis frameworks generate images based on user inputs in a single modality, such as text, segmentation, sketch, or style reference. They are often unable to leverage multimodal user inputs when available, which reduces their practicality. To address this limitation, we propose the Product-of-Experts Generative Adversarial Networks (PoE-GAN) framework, which can synthesize images conditioned on multiple input modalities or any subset of them, even the empty set. PoE-GAN consists of a product-of-experts generator and a multimodal multiscale projection discriminator…
University of Electronic Science and Technology of China（电子科技大学）
Recently, generative adversarial networks (GANs) have shown great advantages in synthesizing images, leading to a boost of explorations of using faked images to augment data. This paper proposes a multimodal cascaded generative adversarial networks (PMC-GANs) to generate realistic and diversified pedestrian images and augment pedestrian detection data. The generator of our model applies a residual U-net structure, with multi-scale residual blocks to encode features, and attention residual blocks to help decode and rebuild pedestrian images. The model constructs in a coarse-to-fine fashion and …
Generating Multimodal Images with GAN: Integrating Text, Image, and Style
Northeastern University（东北大学）；Washington University in St. Louis（圣路易斯华盛顿大学）；Tsinghua University（清华大学）；Montclair State University（蒙特克莱尔州立大学）；Northern Arizona University（北亚利桑那大学）
提出一种基于 GAN 的多模态图像生成方法，通过文本、图像与风格编码模块及多重一致性损失，在多个公开数据集上显著提升生成图像的清晰度与风格一致性。
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；Shenzhen University（深圳大学）；Renmin University of China（中国人民大学）；Harbin Engineering University（哈尔滨工程大学）
Using multimodal neuroimaging data to characterize brain network is currently an advanced technique for Alzheimer's disease(AD) Analysis. Over recent years the neuroimaging community has made tremendous progress in the study of resting-state functional magnetic resonance imaging (rs-fMRI) derived from blood-oxygen-level-dependent (BOLD) signals and Diffusion Tensor Imaging (DTI) derived from white matter fiber tractography. However, Due to the heterogeneity and complexity between BOLD signals and fiber tractography, Most existing multimodal data fusion algorithms can not sufficiently take adva…
In this paper, we present Goal-GAN, an interpretable and end-to-end trainable model for human trajectory prediction. Inspired by human navigation, we model the task of trajectory prediction as an intuitive two-stage process: (i) goal estimation, which predicts the most likely target positions of the agent, followed by a (ii) routing module which estimates a set of plausible trajectories that route towards the estimated goal. We leverage information about the past trajectory and visual context of the scene to estimate a multi-modal probability distribution over the possible goal positions, whic…
Understanding and predicting the intention of pedestrians is essential to enable autonomous vehicles and mobile robots to navigate crowds. This problem becomes increasingly complex when we consider the uncertainty and multimodality of pedestrian motion, as well as the implicit interactions between members of a crowd, including any response to a vehicle. Our approach, Probabilistic Crowd GAN, extends recent work in trajectory prediction, combining Recurrent Neural Networks (RNNs) with Mixture Density Networks (MDNs) to output probabilistic multimodal predictions, from which likely modal paths a…
Stanford University（斯坦福大学）；Aibee Inc（Aibee公司）；University of Adelaide（阿德莱德大学）
Predicting the future trajectories of multiple interacting agents in a scene has become an increasingly important problem for many different applications ranging from control of autonomous vehicles and social robots to security and surveillance. This problem is compounded by the presence of social interactions between humans and their physical interactions with the scene. While the existing literature has explored some of these cues, they mainly ignored the multimodal nature of each human's future trajectory. In this paper, we present Social-BiGAT, a graph-based generative adversarial network …
Disentangled Multimodal Brain MR Image Translation via Transformer-based Modality Infuser
Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School（马萨诸塞州总医院与哈佛医学院戈登医学影像中心）；Korea Advanced Institute of Science and Technology（韩国科学技术院）
A Tactical Behaviour Recognition Framework Based on Causal Multimodal Reasoning: A Study on Covert Audio-Video Analysis Combining GAN Structure Enhancement and Phonetic Accent Modelling
Dhurakij Pundit University（易三仓大学）；The University of Western Australia（西澳大利亚大学）；Association for Computing Machinery（美国计算机协会）；Royal Anthropological Institute（英国皇家人类学学会）
University of Electronic Science and Technology of China（电子科技大学）
We study the problem of multimodal generative modelling of images based on generative adversarial networks (GANs). Despite the success of existing methods, they often ignore the underlying structure of vision data or its multimodal generation characteristics. To address this problem, we introduce the Dirichlet prior for multimodal image generation, which leads to a new Latent Dirichlet Allocation based GAN (LDAGAN). In detail, for the generative process modelling, LDAGAN defines a generative mode for each sample, determining which generative sub-process it belongs to. For the adversarial train…
School of Computing Science（计算科学学院）；Google（谷歌）；Simon Fraser University（西蒙弗雷泽大学）
A persistent challenge in conditional image synthesis has been to generate diverse output images from the same input image despite only one output image being observed per input image. GAN-based methods are prone to mode collapse, which leads to low diversity. To get around this, we leverage Implicit Maximum Likelihood Estimation (IMLE) which can overcome mode collapse fundamentally. IMLE uses the same generator as GANs but trains it with a different, non-adversarial objective which ensures each observed image has a generated sample nearby. Unfortunately, to generate high-fidelity images, prio…
Uppsala University（乌普萨拉大学）；University of Copenhagen（哥本哈根大学）
Despite current advancement in the field of biomedical image processing, propelled by the deep learning revolution, multimodal image registration, due to its several challenges, is still often performed manually by specialists. The recent success of image-to-image (I2I) translation in computer vision applications and its growing use in biomedical areas provide a tempting possibility of transforming the multimodal registration problem into a, potentially easier, monomodal one. We conduct an empirical study of the applicability of modern I2I translation methods for the task of rigid registration…
Korea University（高丽大学）；University of North Carolina at Charlotte（北卡罗来纳大学夏洛特分校）
Recently, generative adversarial networks (GANs) have shown promising performance in generating realistic images. However, they often struggle in learning complex underlying modalities in a given dataset, resulting in poor-quality generated images. To mitigate this problem, we present a novel approach called mixture of experts GAN (MEGAN), an ensemble approach of multiple generator networks. Each generator network in MEGAN specializes in generating images with a particular subset of modalities, e.g., an image class. Instead of incorporating a separate step of handcrafted clustering of multiple…
The University of Tokyo（东京大学）；National Institute of Informatics（国立信息学研究所）；University of Cambridge（剑桥大学）；Cancer Research UK Cambridge Institute（英国癌症研究院剑桥研究所）；University of Milano-Bicocca（米兰比可卡大学）；Chubu University（中部大学）；Jikei University School of Medicine（东京慈惠会医科大学）；Kyushu University（九州大学）
Convolutional Neural Networks (CNNs) achieve excellent computer-assisted diagnosis with sufficient annotated training data. However, most medical imaging datasets are small and fragmented. In this context, Generative Adversarial Networks (GANs) can synthesize realistic/diverse additional training images to fill the data lack in the real image distribution; researchers have improved classification by augmenting data with noise-to-image (e.g., random noise samples to diverse pathological images) or image-to-image GANs (e.g., a benign image to a malignant one). Yet, no research has reported resul…
Generative adversarial networks (GANs) are unsupervised Deep Learning approach in the computer vision community which has gained significant attention from the last few years in identifying the internal structure of multimodal medical imaging data. The adversarial network simultaneously generates realistic medical images and corresponding annotations, which proven to be useful in many cases such as image augmentation, image registration, medical image generation, image reconstruction, and image-to-image translation. These properties bring the attention of the researcher in the field of medical…
Pedestrian trajectory prediction is challenging due to its uncertain and multimodal nature. While generative adversarial networks can learn a distribution over future trajectories, they tend to predict out-of-distribution samples when the distribution of future trajectories is a mixture of multiple, possibly disconnected modes. To address this issue, we propose a multi-generator model for pedestrian trajectory prediction. Each generator specializes in learning a distribution over trajectories routing towards one of the primary modes in the scene, while a second network learns a categorical dis…
When trained on multimodal image datasets, normal Generative Adversarial Networks (GANs) are usually outperformed by class-conditional GANs and ensemble GANs, but conditional GANs is restricted to labeled datasets and ensemble GANs lack efficiency. We propose a novel GAN variant called virtual conditional GAN (vcGAN) which is not only an ensemble GAN with multiple generative paths while adding almost zero network parameters, but also a conditional GAN that can be trained on unlabeled datasets without explicit clustering steps or objectives other than the adversary loss. Inside the vcGAN's gene…
Stanford University（斯坦福大学）；École Polytechnique Fédérate de Lausanne（洛桑联邦理工学院）
Understanding human motion behavior is critical for autonomous moving platforms (like self-driving cars and social robots) if they are to navigate human-centric environments. This is challenging because human motion is inherently multimodal: given a history of human motion paths, there are many socially plausible ways that people could move in the future. We tackle this problem by combining tools from sequence prediction and generative adversarial networks: a recurrent sequence-to-sequence model observes motion histories and predicts future behavior, using a novel pooling mechanism to aggregat…
University of California, Berkeley（加州大学伯克利分校）；University of Toronto（多伦多大学）；Nanjing University（南京大学）
Many tasks in computer vision and graphics fall within the framework of conditional image synthesis. In recent years, generative adversarial nets (GANs) have delivered impressive advances in quality of synthesized images. However, it remains a challenge to generate both diverse and plausible images for the same input, due to the problem of mode collapse. In this paper, we develop a new generic multimodal conditional image synthesis method based on Implicit Maximum Likelihood Estimation (IMLE) and demonstrate improved multimodal image synthesis performance on two tasks, single image super-resol…
This paper addresses the problem of media retrieval using a multimodal query (a query which combines visual input with additional semantic information in natural language feedback). We propose a SynthTriplet GAN framework which resolves this task by expanding the multimodal query with a synthetically generated image that captures semantic information from both image and text input. We introduce a novel triplet mining method that uses a synthetic image as an anchor to directly optimize for embedding distances of generated and target images. We demonstrate that apart from the added value of retr…
Echocardiography to Cardiac MRI View Transformation for Real-Time Blind Restoration
Tampere University（坦佩雷大学）；Qatar University（卡塔尔大学）；VTT Technical Research Centre of Finland（芬兰国家技术研究中心）；Hamad Medical Corporation Hospital（哈马德医疗公司医院）；Hayatabad Medical Complex（海亚特阿巴德医疗中心）
Institute of Computing Technology, CAS（中国科学院计算技术研究所）；University of Chinese Academy of Sciences（中国科学院大学）；Peng Cheng Laboratory（鹏城实验室）
Conditional image generation is an active research topic including text2image and image translation. Recently image manipulation with linguistic instruction brings new challenges of multimodal conditional generation. However, traditional conditional image generation models mainly focus on generating high-quality and visually realistic images, and lack resolving the partial consistency between image and instruction. To address this issue, we propose an Increment Reasoning Generative Adversarial Network (IR-GAN), which aims to reason the consistency between visual increment in images and semanti…
King Abdullah University for Science and Technology (KAUST)（阿卜杜拉国王科技大学）
In multimodal unsupervised image-to-image translation tasks, the goal is to translate an image from the source domain to many images in the target domain. We present a simple method that produces higher quality images than current state-of-the-art while maintaining the same amount of multimodal diversity. Previous methods follow the unconditional approach of trying to map the latent code directly to a full-size image. This leads to complicated network architectures with several introduced hyperparameters to tune. By treating the latent code as a modifier of the convolutional filters, we produc…
Effective fusion of data from multiple modalities, such as video, speech, and text, is challenging due to the heterogeneous nature of multimodal data. In this paper, we propose adaptive fusion techniques that aim to model context from different modalities effectively. Instead of defining a deterministic fusion operation, such as concatenation, for the network, we let the network decide "how" to combine a given set of multimodal features more effectively. We propose two networks: 1) Auto-Fusion, which learns to compress information from different modalities while preserving the context, and 2) …
Longitudinal NSCLC Treatment Progression via Multimodal Generative Models
Unit of Artificial Intelligence and Computer Systems, Department of Engineering, Università Campus Bio-Medico di Roma, Italy（人工智能与计算机系统单位，工程系，罗马大学生物医学学院）；Multi-Specialist Clinical Institute for Orthopaedic Trauma Care (COT), Messina, Italy（骨科创伤护理多学科临床研究所（COT），意大利Messina）；Department of Diagnostics and Intervention, Radiation Physics, Biomedical Engineering, Umeå University, Sweden（诊断与介入系，放射物理，生物医学工程，乌梅大学，瑞典）；Operative Research Unit of Radiation Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy（放射肿瘤手术研究单位，大学生物医学学院基金会，罗马，意大利）；Research Unit of Radiation Oncology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Italy（放射肿瘤研究单位，医学与外科系，罗马大学生物医学学院，意大利）；Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland（生物医学工程系，巴塞尔大学，瑞士Allschwil）；Department of Naval, Electrical, Electronics and Telecommunications Engineering, University of Genoa, Italy（海军、电气、电子与电信工程系，热那亚大学，意大利）
We propose contrastive coding to learn shared, dense image representations, referred to as CoMIRs (Contrastive Multimodal Image Representations). CoMIRs enable the registration of multimodal images where existing registration methods often fail due to a lack of sufficiently similar image structures. CoMIRs reduce the multimodal registration problem to a monomodal one, in which general intensity-based, as well as feature-based, registration algorithms can be applied. The method involves training one neural network per modality on aligned images, using a contrastive loss based on noise-contrasti…
a Division of Medical Informatics, Department of Biomedical Engineering, Link\" o ping University, Link\" o ping, Sweden b Division of Statistics；Machine Learning, Department of Computer；Information Science, Link\" o ping University, Link\" o ping, Sweden c Center for Medical Image Science；Visualization (CMIV), Link\" o ping University, Link\" o ping, Sweden
In medical imaging, a general problem is that it is costly and time consuming to collect high quality data from healthy and diseased subjects. Generative adversarial networks (GANs) is a deep learning method that has been developed for synthesizing data. GANs can thereby be used to generate more realistic training data, to improve classification performance of machine learning algorithms. Another application of GANs is image-to-image translations, e.g. generating magnetic resonance (MR) images from computed tomography (CT) images, which can be used to obtain multimodal datasets from a single m…
Deep generative models such as GANs have driven impressive advances in conditional image synthesis in recent years. A persistent challenge has been to generate diverse versions of output images from the same input image, due to the problem of mode collapse: because only one ground truth output image is given per input image, only one mode of the conditional distribution is modelled. In this paper, we focus on this problem of multimodal conditional image synthesis and build on the recently proposed technique of Implicit Maximum Likelihood Estimation (IMLE). Prior IMLE-based methods required dif…
Segmenting the fine structure of the mouse brain on magnetic resonance (MR) images is critical for delineating morphological regions, analyzing brain function, and understanding their relationships. Compared to a single MRI modality, multimodal MRI data provide complementary tissue features that can be exploited by deep learning models, resulting in better segmentation results. However, multimodal mouse brain MRI data is often lacking, making automatic segmentation of mouse brain fine structure a very challenging task. To address this issue, it is necessary to fuse multimodal MRI data to produ…
Multimodal image-to-image translation (I2IT) aims to learn a conditional distribution that explores multiple possible images in the target domain given an input image in the source domain. Conditional generative adversarial networks (cGANs) are often adopted for modeling such a conditional distribution. However, cGANs are prone to ignore the latent code and learn a unimodal distribution in conditional image synthesis, which is also known as the mode collapse issue of GANs. To solve the problem, we propose a simple yet effective method that explicitly estimates and maximizes the mutual informat…
Fast Fourier Convolutional GAN for 30 m Clear-Sky Land Surface Temperature Gap-Free Reconstruction
Technical University of Munich（慕尼黑工业大学）；Helmholtz Centre for Polar and Marine Research, Alfred Wegener Institute（亥姆霍兹极地与海洋研究中心阿尔弗雷德·韦格纳研究所）；Swiss Federal Institute of Technology Zurich (ETH Zurich)（瑞士联邦理工学院苏黎世分校）
University of Illinois at Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）
We show how to learn a map that takes a content code, derived from a face image, and a randomly chosen style code to an anime image. We derive an adversarial loss from our simple and effective definitions of style and content. This adversarial loss guarantees the map is diverse -- a very wide range of anime can be produced from a single content code. Under plausible assumptions, the map is not just diverse, but also correctly represents the probability of an anime, conditioned on an input face. In contrast, current multimodal generation procedures cannot capture the complex styles that appear …
Story visualization aims to generate a sequence of images to narrate each sentence in a multi-sentence story, where the images should be realistic and keep global consistency across dynamic scenes and characters. Current works face the problem of semantic misalignment because of their fixed architecture and diversity of input modalities. To address this problem, we explore the semantic alignment between text and image representations by learning to match their semantic levels in the GAN-based generative model. More specifically, we introduce dynamic interactions according to learning to dynami…
Shanghai AI Laboratory（上海人工智能实验室）；Tencent AI Lab（腾讯人工智能实验室）；CUHK（香港中文大学）；SenseTime Research（商汤科技研究院）
Multimodal ambiguity and color bleeding remain challenging in colorization. To tackle these problems, we propose a new GAN-based colorization approach PalGAN, integrated with palette estimation and chromatic attention. To circumvent the multimodality issue, we present a new colorization formulation that estimates a probabilistic palette from the input gray image first, then conducts color assignment conditioned on the palette through a generative model. Further, we handle color bleeding with chromatic attention. It studies color affinities by considering both semantic and intensity correlation…
Virginia Tech（弗吉尼亚理工大学）；U. S. Army Corps of Engineers（美国陆军工程兵团）；Google Inc.（谷歌公司）
Deriving event storylines is an effective summarization method to succinctly organize extensive information, which can significantly alleviate the pain of information overload. The critical challenge is the lack of widely recognized definition of storyline metric. Prior studies have developed various approaches based on different assumptions about users' interests. These works can extract interesting patterns, but their assumptions do not guarantee that the derived patterns will match users' preference. On the other hand, their exclusiveness of single modality source misses cross-modality info…
University of Southern California（南加州大学）；Pinscreen；USC Institute for Creative Technologies（南加州大学创新技术研究院）
Generative adversarial networks (GANs) are highly effective unsupervised learning frameworks that can generate very sharp data, even for data such as images with complex, highly multimodal distributions. However GANs are known to be very hard to train, suffering from problems such as mode collapse and disturbing visual artifacts. Batch normalization (BN) techniques have been introduced to address the training. Though BN accelerates the training in the beginning, our experiments show that the use of BN can be unstable and negatively impact the quality of the trained model. The evaluation of BN …
Chinese Academy of Sciences（中国科学院）；University of Chinese Academy of Sciences（中国科学院大学）；Walton Institute for Information and Communication Systems Science（沃尔顿信息与通信系统科学研究所）；Waterford Institute of Technology（沃特福德理工学院）；University of Johannesburg（约翰内斯堡大学）；University of Sindh（信德大学）；Sungkyunkwan University（成均馆大学）
Deep learning based single image super resolution (SISR) algorithms has revolutionized the overall diagnosis framework by continually improving the architectural components and training strategies associated with convolutional neural networks (CNN) on low-resolution images. However, existing work lacks in two ways: i) the SR output produced exhibits poor texture details, and often produce blurred edges, ii) most of the models have been developed for a single modality, hence, require modification to adapt to a new one. This work addresses (i) by proposing generative adversarial network (GAN) wi…
Centre for Medical Image Computing, University College London（伦敦大学学院医学图像计算中心）；Institute of Biomedical Engineering, University of Oxford（牛津大学生物医学工程研究所）；Department of Diagnostic Imaging, Royal Free London NHS Foundation Trust（伦敦皇家自由NHS基金会信托诊断影像科）
Sonography synthesis has a wide range of applications, including medical procedure simulation, clinical training and multimodality image registration. In this paper, we propose a machine learning approach to simulate ultrasound images at given 3D spatial locations (relative to the patient anatomy), based on conditional generative adversarial networks (GANs). In particular, we introduce a novel neural network architecture that can sample anatomically accurate images conditionally on spatial position of the (real or mock) freehand ultrasound probe. To ensure an effective and efficient spatial in…
Research Institute of Trustworthy Autonomous Systems, Southern University of Science and Technology（南方科技大学可信自主系统研究院）；Southern University of Science and Technology（南方科技大学）；School of Electrical and Electronic Engineering, Huazhong University of Science and Technology（华中科技大学电气与电子工程学院）；Huazhong University of Science and Technology（华中科技大学）
Despite significant advances in image-to-image (I2I) translation with generative adversarial networks (GANs), it remains challenging to effectively translate an image to a set of diverse images in multiple target domains using a single pair of generator and discriminator. Existing I2I translation methods adopt multiple domain-specific content encoders for different domains, where each domain-specific content encoder is trained with images from the same domain only. Nevertheless, we argue that the content (domain-invariance) features should be learned from images among all of the domains. Conse…
A Survey on fMRI-based Brain Decoding for Reconstructing Multimodal Stimuli
Beijing Institute of Basic Medical Sciences（北京基础医学研究所）；School of Computer Science and Information Engineering, Hefei University of Technology (HFUT)（合肥工业大学计算机与信息工程学院）；Institute of Artificial Intelligence, Hefei Comprehensive National Science Center（合肥综合性国家科学中心人工智能研究院）；Zhejiang University（浙江大学）；Australian Artificial Intelligence Institute, Faculty of Engineering and Information Technology, University of Technology Sydney（悉尼科技大学工程与信息技术学院澳大利亚人工智能研究所）；School of Information Science and Technology, University of Science and Technology of China（中国科学技术大学信息科学技术学院）
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). A reliable measure of the tissue myelin content is therefore essential for the understanding of the physiopathology of MS, tracking progression and assessing treatment efficacy. Positron emission tomography (PET) with $[^{11} \mbox{C}] \mbox{PIB}$ has been proposed as a promising biomarker for measuring myelin content changes in-vivo in MS. However, PET imaging is expensive and invasive due to the injection of a radioactive tracer. On the contrary, magnetic resonance imaging (MRI) is a non-invasive, widely …
