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arXiv 1801.09810cs.LGcs.AI
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基于上下文解释网络的个性化生存预测

Personalized Survival Prediction with Contextual Explanation Networks

Carnegie Mellon University(卡内基梅隆大学)

Maruan Al-Shedivat, Avinava Dubey, Eric P. Xing

摘要:

在个体患者水平上准确和透明地预测癌症存活时间可以告知和改善患者护理和治疗实践。在本文中,我们设计了一个模型,同时学习准确预测患者特定的生存分布,并解释其预测的患者属性,如临床测试或评估。我们的模型是灵活的,并基于一个循环网络,可以处理各种形式的数据,包括时间测量,但构造和使用简单的解释,在病人和时间特定的线性回归的形式。为了进行分析,我们使用了两个公开的数据集,并表明我们的网络在预测方面优于许多基线,同时提供了一种检查每个预测背后原因的方法。

英文摘要:

Accurate and transparent prediction of cancer survival times on the level of individual patients can inform and improve patient care and treatment practices. In this paper, we design a model that concurrently learns to accurately predict patient-specific survival distributions and to explain its predictions in terms of patient attributes such as clinical tests or assessments. Our model is flexible and based on a recurrent network, can handle various modalities of data including temporal measurements, and yet constructs and uses simple explanations in the form of patient- and time-specific linear regression. For analysis, we use two publicly available datasets and show that our networks outperform a number of baselines in prediction while providing a way to inspect the reasons behind each prediction.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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