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arXiv 1608.07014math.STstat.MEstat.TH
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广义差错控制序贯多重检验的渐近最优性理论

Sequential multiple testing with generalized error control: an asymptotic optimality theory

Yanglei Song, Georgios Fellouris

摘要:

在两个广义误差度量下研究了序贯多重检验问题。在第一种情况下,至少控制任何类型的$k$错误的概率。在第二种情况下,同时控制至少$k_1$假阳性和至少$k_2$假阴性的概率。对于每个配方,最佳预期的样本量的特点,一阶渐近近似的误差概率为0,并提出了一种新的多重检验程序,并证明是渐近有效的每个信号配置下。当各种假设的数据流是独立的并且每个局部对数似然比统计量满足某个强大数律时,这些结果成立。在i.i.d.的特殊情况下。在每个流中的观察,所提出的顺序程序超过固定样本量计划的收益进行了量化。

英文摘要:

The sequential multiple testing problem is considered under two generalized error metrics. Under the first one, the probability of at least $k$ mistakes, of any kind, is controlled. Under the second, the probabilities of at least $k_1$ false positives and at least $k_2$ false negatives are simultaneously controlled. For each formulation, the optimal expected sample size is characterized, to a first-order asymptotic approximation as the error probabilities go to 0, and a novel multiple testing procedure is proposed and shown to be asymptotically efficient under every signal configuration. These results are established when the data streams for the various hypotheses are independent and each local log-likelihood ratio statistic satisfies a certain Strong Law of Large Numbers. In the special case of i.i.d. observations in each stream, the gains of the proposed sequential procedures over fixed-sample size schemes are quantified.

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